Search Results - (Author, Cooperation:H. Hahn)
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1M. R. Gardner ; L. M. Kattenhorn ; H. R. Kondur ; M. von Schaewen ; T. Dorfman ; J. J. Chiang ; K. G. Haworth ; J. M. Decker ; M. D. Alpert ; C. C. Bailey ; E. S. Neale, Jr. ; C. H. Fellinger ; V. R. Joshi ; S. P. Fuchs ; J. M. Martinez-Navio ; B. D. Quinlan ; A. Y. Yao ; H. Mouquet ; J. Gorman ; B. Zhang ; P. Poignard ; M. C. Nussenzweig ; D. R. Burton ; P. D. Kwong ; M. Piatak, Jr. ; J. D. Lifson ; G. Gao ; R. C. Desrosiers ; D. T. Evans ; B. H. Hahn ; A. Ploss ; P. M. Cannon ; M. S. Seaman ; M. Farzan
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AIDS Vaccines/genetics/immunology ; Animals ; Antibodies, Neutralizing/immunology ; Antigens, CD4/genetics/*immunology ; CCR5 Receptor Antagonists/immunology ; Dependovirus/*genetics ; Female ; Genetic Therapy ; HIV Antibodies/immunology ; HIV-1/immunology ; HIV-2/immunology ; Immunoglobulins/genetics/*immunology ; Macaca mulatta ; Male ; Neutralization Tests ; Receptors, CCR5/metabolism ; Simian Acquired Immunodeficiency Syndrome/*immunology/*prevention & ; control/virology ; Simian Immunodeficiency Virus/*immunology ; *Virus InternalizationPublished by: -
2X. Zeng ; R. Kieffer ; B. Glettner ; C. Nurnberger ; F. Liu ; K. Pelz ; M. Prehm ; U. Baumeister ; H. Hahn ; H. Lang ; G. A. Gehring ; C. H. Weber ; J. K. Hobbs ; C. Tschierske ; G. Ungar
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-03-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Staff View
Publication Date: 2018-09-22Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
4H. X. Liao ; R. Lynch ; T. Zhou ; F. Gao ; S. M. Alam ; S. D. Boyd ; A. Z. Fire ; K. M. Roskin ; C. A. Schramm ; Z. Zhang ; J. Zhu ; L. Shapiro ; J. C. Mullikin ; S. Gnanakaran ; P. Hraber ; K. Wiehe ; G. Kelsoe ; G. Yang ; S. M. Xia ; D. C. Montefiori ; R. Parks ; K. E. Lloyd ; R. M. Scearce ; K. A. Soderberg ; M. Cohen ; G. Kamanga ; M. K. Louder ; L. M. Tran ; Y. Chen ; F. Cai ; S. Chen ; S. Moquin ; X. Du ; M. G. Joyce ; S. Srivatsan ; B. Zhang ; A. Zheng ; G. M. Shaw ; B. H. Hahn ; T. B. Kepler ; B. T. Korber ; P. D. Kwong ; J. R. Mascola ; B. F. Haynes
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-04-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AIDS Vaccines/immunology ; Africa ; Amino Acid Sequence ; Antibodies, Monoclonal/chemistry/genetics/immunology ; Antibodies, Neutralizing/*chemistry/genetics/*immunology ; Antigens, CD4/chemistry/immunology ; Cell Lineage ; Cells, Cultured ; Clone Cells/cytology ; Cross Reactions/immunology ; Crystallography, X-Ray ; Epitopes/chemistry/immunology ; *Evolution, Molecular ; HIV Antibodies/*chemistry/genetics/*immunology ; HIV Envelope Protein gp120/chemistry/genetics/immunology/metabolism ; HIV-1/*chemistry/classification/*immunology ; Humans ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Neutralization Tests ; Phylogeny ; Protein Structure, TertiaryPublished by: -
5Ruian Ke, Hui Li, Shuyi Wang, Wenge Ding, Ruy M. Ribeiro, Elena E. Giorgi, Tanmoy Bhattacharya, Richard J. O. Barnard, Beatrice H. Hahn, George M. Shaw, Alan S. Perelson
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-07-25Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
6J. Prado-Martinez ; P. H. Sudmant ; J. M. Kidd ; H. Li ; J. L. Kelley ; B. Lorente-Galdos ; K. R. Veeramah ; A. E. Woerner ; T. D. O'Connor ; G. Santpere ; A. Cagan ; C. Theunert ; F. Casals ; H. Laayouni ; K. Munch ; A. Hobolth ; A. E. Halager ; M. Malig ; J. Hernandez-Rodriguez ; I. Hernando-Herraez ; K. Prufer ; M. Pybus ; L. Johnstone ; M. Lachmann ; C. Alkan ; D. Twigg ; N. Petit ; C. Baker ; F. Hormozdiari ; M. Fernandez-Callejo ; M. Dabad ; M. L. Wilson ; L. Stevison ; C. Camprubi ; T. Carvalho ; A. Ruiz-Herrera ; L. Vives ; M. Mele ; T. Abello ; I. Kondova ; R. E. Bontrop ; A. Pusey ; F. Lankester ; J. A. Kiyang ; R. A. Bergl ; E. Lonsdorf ; S. Myers ; M. Ventura ; P. Gagneux ; D. Comas ; H. Siegismund ; J. Blanc ; L. Agueda-Calpena ; M. Gut ; L. Fulton ; S. A. Tishkoff ; J. C. Mullikin ; R. K. Wilson ; I. G. Gut ; M. K. Gonder ; O. A. Ryder ; B. H. Hahn ; A. Navarro ; J. M. Akey ; J. Bertranpetit ; D. Reich ; T. Mailund ; M. H. Schierup ; C. Hvilsom ; A. M. Andres ; J. D. Wall ; C. D. Bustamante ; M. F. Hammer ; E. E. Eichler ; T. Marques-Bonet
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Africa ; Animals ; Animals, Wild/genetics ; Animals, Zoo/genetics ; Asia, Southeastern ; Evolution, Molecular ; Gene Flow/genetics ; *Genetic Variation ; Genetics, Population ; Genome/genetics ; Gorilla gorilla/classification/genetics ; Hominidae/classification/*genetics ; Humans ; Inbreeding ; Pan paniscus/classification/genetics ; Pan troglodytes/classification/genetics ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Population DensityPublished by: -
7P. M. Sharp ; J. C. Rayner ; B. H. Hahn
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-04-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Acquired Immunodeficiency Syndrome/*transmission/virology ; Animals ; *Biological Evolution ; Genetic Predisposition to Disease ; HIV-1/physiology ; Hominidae/*parasitology/*virology ; Host-Parasite Interactions/genetics ; Host-Pathogen Interactions/genetics ; Humans ; Malaria, Falciparum/genetics/parasitology/*transmission ; Mutation ; N-Acetylneuraminic Acid/biosynthesis/genetics ; Plasmodium falciparum/physiology ; Zoonoses/parasitology/*transmission/virologyPublished by: -
8Staff View
Publication Date: 2018-09-05Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
9Bornstein, M. H., Hahn, C.-S., Putnick, D. L., Pearson, R. M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-22Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
10T. Schoofs ; F. Klein ; M. Braunschweig ; E. F. Kreider ; A. Feldmann ; L. Nogueira ; T. Oliveira ; J. C. Lorenzi ; E. H. Parrish ; G. H. Learn ; A. P. West, Jr. ; P. J. Bjorkman ; S. J. Schlesinger ; M. S. Seaman ; J. Czartoski ; M. J. McElrath ; N. Pfeifer ; B. H. Hahn ; M. Caskey ; M. C. Nussenzweig
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-05-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
11Fischer, U. ; Ertle, R. ; Abel, P. ; Rebrin, K. ; Brunstein, E. ; Dorsche, H. Hahn ; Freyse, E. J.
Springer
Published 1987Staff ViewISSN: 1432-0428Keywords: Subcutaneous glucose concentration ; wick technique ; enzyme sensorSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Employing saline-impregnated cotton threads, an implanted-wick technique was adopted in dogs to obtain specimen from the subcutaneous interstitial compartment in order to estimate its glucose concentration. By measuring the protein, potassium and haemoglobin contents, the centrifuged wick fluid was shown to contain the interstitial concentration of solutes after an equilibration time of approximately 15 min. In normal and in diabetic animals the steady state subcutaneous glucose concentration was almost identical to the circulating glucose level when ranged between 2 and 25 mmol/l. Slow alterations in the circulating glucose profile such as those which appear during an oral glucose tolerance test are closely mirrored by the respective levels in the wick fluid. Fast alterations, however, show deviations. The wick-based glucose levels are well paralleled by the current of Clark type glucose oxidase sensors implanted at the same site. Since, on the basis of in vitro calibrations the sensor outputs have only indicated apparent tissue glucose concentrations of between 70 and 90% of glycaemia, another reference is needed for calibration. Under steady state conditions, the wick method, and on this basis in routine measurements the blood glucose concentration, may be recommended as a reference of implanted sensors which can otherwise not be calibrated in situ.Type of Medium: Electronic ResourceURL: -
12Aufnahme von Zink-65 in Mastzellen nach Degranulierung durch KupferdinatriumäthylendiamintetraacetatStaff View
ISSN: 1432-119XSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineDescription / Table of Contents: Zusammenfassung Wistar-Ratten wurde intravenös Kupferdinatriumäthylendiamintetraacetat (Cu-EDTA, ein neuer Mastzellendegranulator) und danach in variierten Zeitabständen 65Zn verabreicht. Die selektive Anreicherung von 65Zn in den Mastzellen ist bereits 30 min nach der Cu-EDTA-Gabe gegenüber den Kontrollgruppen deutlich gesteigert. Die Beladung mit 65Zn wird bei einem Intervall von 1 Std noch verstärkt und bleibt dann bis zu 1 Woche unverändert erhalten. Wenn der Abstand zwischen den beiden Injektionen auf 2 Wochen ausgedehnt wird, nimmt die Akkumulation des 65Zn in den Mastzellen wieder ab. Die Selektivität der Zinkaufnahme in die Mastzellen ist auch bei nicht vorbehandelten Ratten festzustellen. Die unterschiedlichen Auffassungen über die Bedeutung des Zinks für die Mastzellen werden diskutiert, wobei auf den hohen Zinkgehalt anderer Drüsenzellen mit Speicherfunktion (endo- und exokrines Pankreas) hingewiesen wird.Notes: Summary Wistar rats were intravenously injected with copper disodium ethylenediamine tetraacetate (Cu-EDTA, a new mast cell discharger) and in varied intervals with 65Zn. The selective enrichment of 65Zn in the mast cells is already increased 30 minutes after the administration of Cu-EDTA in comparison to the control groups. Regarding an interval of 1 hour the uptake of 65Zn is further increased and remains in this intensity up to 1 week. When the distance between the two injections is enlarged to two weeks, the accumulation of 65Zn in the mast cells decreases. The selectivity of 65Zn uptake by mast cells can be demonstrated in not preloaded rats, too. Taking in consideration the high zinc content of other glandular cells with storage function (endocrine and exocrine pancreas) the different opinions about the significance of zinc for the mast cells were discussed.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1432-119XSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary The expression patterns of individual cytokeratin polypeptides in foetal and adult human pancreatic tissues were examined using monoclonal antibodies. We demonstrated that human pancreatic epithelia in early stages of development (14 weeks of gestation) contain cytokeratins 7, 8, 18 and 19, which are typical of simple epithelia, as well as cytokeratin 4 and 17, which are characteristic of stratified epithelia. In the pancreatic ducts, most of these cytokeratins appeared to be expressed together. Cytokeratins 1, 5, 10, 13, 16 and 20 were not detectable. In contrast, the pancreatic parenchyma was only positive for cytokeratins 8 and 18, except a transient expression of cytokeratins 7 and 19 in pancreatic islets and acinar cells during the foetal development. A focal cytokeratin 7 staining of single acinar cells was seen in newborn and in adult islets. In the stromal tissue, vascular smooth muscle cells were partly reactive with cytokeratin 8 and 18 specific antibodies. The results are discussed in the light of differentiation-dependent changes in the expression of individual cytokeratin polypeptides in developing epithelia.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1573-6865Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1573-6865Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: In the past, cobalt (II) ions have been added to nickel-zinc ferrites to capitalize on the anisotropic character of Co+2 in stabilizing domain walls and reducing magnetic losses. This paper emphasizes increasing losses. The effect of Co+2 on the real permeability (μ') and magnetic loss (μ‘) when cobalt was sequentially substituted for nickel in stoichiometric nickel-zinc ferrite was measured at 50–1500 MHz. The compositions examined were included in the formulation CoxNi0.5−xZn0.5Fe2O4. in which the cobalt atom fraction x took values from x=0.032 to 0.50. Air density of the measured toroids decreased from 4.52 g/cm3 at x=0.032 to 4.28 g/cm3 at x=0.50. A maximum for μ‘ was found in the region x=0.03–0.04, depending upon the frequency. This increase was marked at the lower frequencies, but it essentially disappeared by 800 MHz. The magnetic loss spectrum for cobalt-zinc ferrite was described by a single relaxation dispersion with a relaxation time of 6.22×10−10 s. As nickel replaced cobalt, the relaxation time increased to 14.9×10−10 s at x=0.032. An earlier analysis of nickel-zinc ferrite (x=0) yielded a relaxation time of 11.9×10−10 s, confirming the approximate coincidence of maxima in both μ‘ and relaxation time. The fact that μ‘ decreases at x(approximately-greater-than)0.04 (as cobalt replaces nickel) does not mean that the reflected attenuation must decrease. Sample thickness also influences the result. For shorted samples 0.250 in. thick, the replacement of nickel by cobalt increased attenuation despite decreasing values of μ‘, and shifted the frequency of maximum attenuation to higher values.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The effectiveness of ferrites as specular radar absorbers may be related to the volumetric concentration of ferrite in the absorber. This relationship is indicated when the performances of ferrite composites are compared, and when the composites are compared with ferrite tiles. The density of a ferrite tile is dependent on both composition and the conditions of preparation. A series of samples with the composition Ni0.5Zn0.5Fe2O4 was prepared by seven different methods to yield ferrites with densities varying from 3.82 to 5.33 g/cm3. Micrographs are presented to illustrate the structural dissimilarities. The highest density was produced by hot isostatic pressing, a procedure that produced two regions of differing grain size. There was relatively little grain growth in the exterior region, but grains in the interior nearly doubled in size. The greatest effects of density on permeability were noted in the 100–200-MHz region. There, the real part of permeability (μ') increased with density up to 5.1 g/cm3. The imaginary part (μ‘) also increased with ferrite density. Since the microstructure greatly influences the magnetic loss, and the many processes used resulted in greatly varying microstructural differences, the increase of both μ' and μ‘ with density was conclusive. The presence of linewidth broadening as a result of energy absorption by various spin-wave modes was confirmed.Type of Medium: Electronic ResourceURL: -
18Alof, C. ; Stahl, B. ; Ghafari, M. ; Hahn, H.
[S.l.] : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The magnetotransport properties of granular thin AgFe films, prepared by codeposition of the constituent metals in an ultrahigh vacuum have been investigated. Mössbauer spectroscopy was employed to investigate the role of scattering of conduction electrons at the interface between the magnetic Fe particles and the Ag matrix. It is possible to determine the ratio of Fe atoms located at the Ag/Fe interface and in the particles (bulk atoms). The giant magnetoresistance effect correlates with the ratio of interface/bulk atoms. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Giant magnetoresistance (GMR) effect in heterogeneous granular Ag–Ni alloys, prepared by utilizing coevaporation of the metals in continuous He flow, is reported. The average grain size, determined from x-ray diffraction (XRD) data, increases from 11 to 28 nm with increasing He pressure. The transmission electron microscope analysis revealed the presence of Ag and Ni isolated grains which give rise to coalescence. The nitrogen adsorption measurements show a decrease of the surface area with increasing pressure confirming the XRD data. Electrical measurements revealed a GMR effect as large as 7%, at room temperature and a magnetic field H=1 T, on the specimen prepared with a final pressure of 800 Pa. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
20Averback, R. S. ; Hahn, H. ; Höfler, H. J. ; Logas, J. C.
Woodbury, NY : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Amorphous Ni-Ti alloys were synthesized by producing nanoscale amorphous Ni-Ti particles and compacting these powders, in situ, in a high vacuum environment. X-ray diffraction measurements revealed that crystallization occurs in these alloys in the temperature range 450–550 °C, although measurements of electrical resistivity and heat release showed that other relaxation processes occur at lower temperatures. The Vicker's hardness of these alloys is ≈350 kg/mm2. The results are discussed in terms of interparticle or grain boundaries in the amorphous alloy.Type of Medium: Electronic ResourceURL: