Search Results - (Author, Cooperation:G. Yuen)
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1Latest Papers from Table of Contents or Articles in PressS. Zha ; C. Guo ; C. Boboila ; V. Oksenych ; H. L. Cheng ; Y. Zhang ; D. R. Wesemann ; G. Yuen ; H. Patel ; P. H. Goff ; R. L. Dubois ; F. W. Alt
Nature Publishing Group (NPG)
Published 2010Staff ViewPublication Date: 2010-12-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Ataxia Telangiectasia Mutated Proteins ; Cell Cycle Proteins/genetics/*metabolism ; Cell Line, Transformed ; Chromatin/metabolism ; Chromosomes, Mammalian/genetics/metabolism ; *DNA Breaks, Double-Stranded ; *DNA Repair ; DNA-Binding Proteins/deficiency/genetics/*metabolism ; Embryo, Mammalian/embryology/metabolism ; *Gene Rearrangement, B-Lymphocyte/genetics ; Histones/*metabolism ; Mice ; Precursor Cells, B-Lymphoid/cytology/metabolism ; Protein-Serine-Threonine Kinases/deficiency/genetics/*metabolism ; *Recombination, Genetic ; Tumor Suppressor Proteins/deficiency/genetics/*metabolismPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0020-1693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0375-9474Keywords: Nuclear FissionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesEpstein, S. ; Krishnamurthy, R. V. ; Cronin, J. R. ; Pizzarello, S. ; Yuen, G. U.
[s.l.] : Nature Publishing Group
Published 1987Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] There have been previous investigations of the isotopic composition of soluble organic compounds from carbonaceous chondrites. Smith and Kaplan3 and Chang and Mack4 measured 613C values of -17 to -5%, for benzene-methanol and 5 to 25%, for water extracts respectively. Chang and Mack also examined ...Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1432-0770Source: Springer Online Journal Archives 1860-2000Topics: BiologyComputer SciencePhysicsNotes: Abstract. Phase-plane analysis of the ionic currents underlying dendritic plateau potentials was carried out to study the nonlinear dynamics and steady-state transfer properties of the dendritic tree in cerebellar Purkinje cells. The results of an analysis of the P-type calcium and delayed rectifier potassium channel system are presented in this study. These channels constitute a simple system that can support bistability and plateau potentials. By requiring both the steady-state current-voltage curve and nullclines to mimic basic plateau potential properties, we obtained well-defined ranges of specific conductance that can support bistability. Hysteresis was found to be surprisingly prevalent in this simple ion-channel system. Using the steady-state current voltage relationship, we derive concise, algebraic expressions for the voltage and current thresholds of state transitions as functions of specific conductance. The significance of bistability in this ion-channel system is discussed with respect to the generation of plateau potentials in Purkinje cells dendrites and the role of the cerebellum in motor control.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1432-0770Source: Springer Online Journal Archives 1860-2000Topics: BiologyComputer SciencePhysicsNotes: Abstract Phase-plane analysis of the ionic currents underlying dendritic plateau potentials was carried out to study the nonlinear dynamics and steady-state transfer properties of the dendritic tree in cerebellar Purkinje cells. The results of an analysis of the P-type calcium and delayed rectifier potassium channel system are presented in this study. These channels constitute a simple system that can support bistability and plateau potentials. By requiring both the steady-state current-voltage curve and nullclines to mimic basic plateau potential properties, we obtained well-defined ranges of specific conductance that can support bistability. Hysteresis was found to be surprisingly prevalent in this simple ion-channel system. Using the steady-state current voltage relationship, we derive concise, algebraic expressions for the voltage and current thresholds of state transitions as functions of specific conductance. The significance of bistability in this ion-channel system is discussed with respect to the generation of plateau potentials in Purkinje cells dendrites and the role of the cerebellum in motor control.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesSchoonderwaldt, H. C. ; Cho Chia Yuen, G. ; Colon, E. J. ; Hommes, O. R. ; Notermans, S. L. H. ; Walder, H. A. D.
Springer
Published 1981Staff ViewISSN: 1432-1459Keywords: Cerebral blood flow ; Normal pressure hydrocephalus ; Doppler LP test ; Cerebrospinal fluid pressureSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Die Ergebnisse dieser Untersuchung bestätigen die Hypothese, daß der einfache, harmlose Doppler-LP-Test ein nützliches Verfahren sein kann, um Information zu bekommen von dem Zusammenhang des Liquordrucks und der zerebralen Blutdurchströmung. Ferner wurde der vorhersehende Wert des Tests untersucht bezüglich des klinischen Erfolges nach Liquordrainage bei Patienten mit Hydrocephalus mit normalem Liquordruck. Es wurden vierzehn Patienten untersucht mit Hydrocephalus mit normalem Liquordruck; acht Patienten zeigten einen positiven und sechs Patienten einen negativen Doppler-LP-Test. Sieben der acht Patienten mit dem positiven Test zeigten eine deutliche Verbesserung nach der Operation, doch keiner der sechs Patienten mit dem negativen Test. Die Schlußfolgerung dieser Untersuchung könnte sein, daß der Doppler-LP-Test ein neuer und brauchbarer preoperativer Selektionstest wäre bei Patienten mit Hydrocephalus mit normalem Liquordruck. Im übrigen unterstützt dieses Studium die Hypothese, daß die Autoregulation der zerebralen Blutdurchströmung gestört sein kann bei Patienten mit Hydrocephalus mit normalem Liquordruck.Notes: Summary The results of this study confirm the hypothesis that the simple innocuous Doppler LP test may be useful in obtaining information about CSFP-CBF (cerebrospinal fluid pressure-cerebral blood flow) relationships. The value of this test in predicting the clinical outcome of CSF shunting in patients with normal pressure hydrocephalus (NPH) was studied. Fourteen patients with NPH were examined; eight patients showed a positive and six patients a negative Doppler LP test. Seven of the eight patients with a positive test improved following the shunting procedure, but none of the six patients with a negative test improved after operation. This study suggests that the Doppler LP test is a useful preoperative selection test in patients with NPH. In addition this study supports the hypothesis that CBF autoregulation may be impaired with NPH.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0006-3525Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The reaction, V amylose hydrate ⇄ H2O + V amylose dehydrate, where the amylose hydrate and dehydrate are pseudohexagonal, helical species with packing diameters of 13.7 and 13.0 A., respectively, has been studied. The V amyloses were exposed to water vapor pressures at various temperatures, with phase determination obtained by identifying solid reactant and product from their x-ray patterns. Reversibility of reaction was found to occur over a 50-96°C. range. A Clausius-Clapeyron plot yields a ΔH of reaction of 10.4 kcal./mole of water released, which value is close to analogous heats of reaction of many common hydrate systems.Additional Material: 1 Ill.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesPigeat, P. ; Pacia, N. ; Yuen, G. Sum ; Weber, B.
Chichester [u.a.] : Wiley-Blackwell
Published 1990Staff ViewISSN: 0142-2421Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: PhysicsType of Medium: Electronic ResourceURL: