Search Results - (Author, Cooperation:G. Yan)
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1Dugan, J. P., Haverkos, B. M., Villagomez, L., Martin, L. K., Lustberg, M., Patton, J., Martin, M., Huang, Y., Nuovo, G., Yan, F., Cavaliere, R., Fingeroth, J., Kenney, S. C., Ambinder, R. F., Lozanski, G., Porcu, P., Caligiuri, M. A., Baiocchi, R. A.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-07-17Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
2Chen, G., Yan, Q., Fang, Y., Wu, L., Krell, P. J., Feng, G.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-05-15Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
3D. E. Neafsey ; R. M. Waterhouse ; M. R. Abai ; S. S. Aganezov ; M. A. Alekseyev ; J. E. Allen ; J. Amon ; B. Arca ; P. Arensburger ; G. Artemov ; L. A. Assour ; H. Basseri ; A. Berlin ; B. W. Birren ; S. A. Blandin ; A. I. Brockman ; T. R. Burkot ; A. Burt ; C. S. Chan ; C. Chauve ; J. C. Chiu ; M. Christensen ; C. Costantini ; V. L. Davidson ; E. Deligianni ; T. Dottorini ; V. Dritsou ; S. B. Gabriel ; W. M. Guelbeogo ; A. B. Hall ; M. V. Han ; T. Hlaing ; D. S. Hughes ; A. M. Jenkins ; X. Jiang ; I. Jungreis ; E. G. Kakani ; M. Kamali ; P. Kemppainen ; R. C. Kennedy ; I. K. Kirmitzoglou ; L. L. Koekemoer ; N. Laban ; N. Langridge ; M. K. Lawniczak ; M. Lirakis ; N. F. Lobo ; E. Lowy ; R. M. MacCallum ; C. Mao ; G. Maslen ; C. Mbogo ; J. McCarthy ; K. Michel ; S. N. Mitchell ; W. Moore ; K. A. Murphy ; A. N. Naumenko ; T. Nolan ; E. M. Novoa ; S. O'Loughlin ; C. Oringanje ; M. A. Oshaghi ; N. Pakpour ; P. A. Papathanos ; A. N. Peery ; M. Povelones ; A. Prakash ; D. P. Price ; A. Rajaraman ; L. J. Reimer ; D. C. Rinker ; A. Rokas ; T. L. Russell ; N. Sagnon ; M. V. Sharakhova ; T. Shea ; F. A. Simao ; F. Simard ; M. A. Slotman ; P. Somboon ; V. Stegniy ; C. J. Struchiner ; G. W. Thomas ; M. Tojo ; P. Topalis ; J. M. Tubio ; M. F. Unger ; J. Vontas ; C. Walton ; C. S. Wilding ; J. H. Willis ; Y. C. Wu ; G. Yan ; E. M. Zdobnov ; X. Zhou ; F. Catteruccia ; G. K. Christophides ; F. H. Collins ; R. S. Cornman ; A. Crisanti ; M. J. Donnelly ; S. J. Emrich ; M. C. Fontaine ; W. Gelbart ; M. W. Hahn ; I. A. Hansen ; P. I. Howell ; F. C. Kafatos ; M. Kellis ; D. Lawson ; C. Louis ; S. Luckhart ; M. A. Muskavitch ; J. M. Ribeiro ; M. A. Riehle ; I. V. Sharakhov ; Z. Tu ; L. J. Zwiebel ; N. J. Besansky
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-01-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anopheles/classification/*genetics ; Base Sequence ; Chromosomes, Insect/genetics ; Drosophila/genetics ; *Evolution, Molecular ; *Genome, Insect ; Humans ; Insect Vectors/classification/*genetics ; Malaria/*transmission ; Molecular Sequence Data ; Phylogeny ; Sequence AlignmentPublished by: -
4Li, K., Hu, C., Xing, F., Gao, M., Liang, J., Xiao, X., Cai, J., Tan, Y., Hu, J., Zhu, W., Yin, W., Li, Y., Chen, W., Lu, B., Mai, J., Qiu, P., Su, X., Yan, G., Zhang, H., Lin, Y.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-02-27Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
5Staff View
Publication Date: 2018-03-24Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
6Staff View
Publication Date: 2018-04-07Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
7Z Y Qu, X Li, X Zou, T L Zhang, W J Zhang, X J Yan, G Z Wang, B Wang and W L Li
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-08-04Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
8P Yan, G F Zhang, B H Shi, W Zheng, Q Jiang, L Gao, Z Shi and Y D Yang
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-11-08Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
9Chao, Jennifer R. ; Ni, Yan G. ; Bolaños, Carlos A. ; Rahman, Zia ; DiLeone, Ralph J. ; Nestler, Eric J.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Adenylyl cyclase (AC) type VIII has been implicated in several forms of neural plasticity, including drug addiction and learning and memory. In the present study, we directly examined the role for the transcription factor CREB (cAMP response element binding protein) in regulating ACVIII expression by cloning a 5.2 kilobase region upstream of the translation start site of the mouse ACVIII gene. Analysis of this fragment revealed consensus elements for several transcription factors, including a canonical cAMP response element (CRE) in close proximity to the transcription initiation region. Next, ACVIII promoter activity was studied in two neural-derived cell lines and in primary cultures of rat striatal neurons. Activation of the cAMP pathway by forskolin treatment increased promoter activity, and a series of deletion and point mutants demonstrated that this activation is mediated specifically via the canonical CRE site. Gel shift assays confirmed that this site can bind CREB and several CREB family proteins. Further, activation of the ACVIII promoter by forskolin was potentiated by expression of a constitutively active form of CREB, CREB-VP16, whereas it was inhibited by expression of a dominant-negative form of CREB, A-CREB. Finally, over-expression of CREB in vivo, by viral-mediated gene transfer, induced ACVIII promoter activity in the brains of ACVIII-LacZ transgenic mice. These results suggest that the ACVIII gene is regulated by CREB in vitro and in vivo and that this regulation may contribute to CREB-dependent neural plasticity.Type of Medium: Electronic ResourceURL: -
10Gold, Stephen J. ; Han, Ming-Hu ; Herman, Amy E. ; Ni, Yan G. ; Pudiak, Cindy M. ; Aghajanian, George K. ; Liu, Rong-Jian ; Potts, Bryan W. ; Mumby, Susanne M. ; Nestler, Eric J.
Oxford, UK : Blackwell Science, Ltd
Published 2003Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The present study explored a possible role for RGS (regulators of G protein signalling) proteins in the long term actions of morphine in the locus coeruleus (LC), a brainstem region implicated in opiate physical dependence and withdrawal. Morphine influences LC neurons through activation of µ-opioid receptors, which, being Gi/o-linked, would be expected to be modulated by RGS proteins. We focused on several RGS subtypes that are known to be expressed in this brain region. Levels of mRNAs encoding RGS2, -3, -4, -5, -7, -8 and -11 are unchanged following chronic morphine, but RGS2 and −4 mRNA levels are increased 2–3-fold 6 h following precipitation of opiate withdrawal. The increases in RGS2 and −4 mRNA peak after 6 h of withdrawal and return to control levels by 24 h. Immunoblot analysis of RGS4 revealed a striking divergence between mRNA and protein responses in LC: protein levels are elevated twofold following chronic morphine and decrease to control values by 6 h of withdrawal. In contrast, levels of RGS7 and −11 proteins, the only other subtypes for which antibodies are available, were not altered by these treatments. Intracellular application of wild-type RGS4, but not a GTPase accelerating-deficient mutant of RGS4, into LC neurons diminished electrophysiological responses to morphine. The observed subtype- and time-specific regulation of RGS4 protein and mRNA, and the diminished morphine-induced currents in the presence of elevated RGS4 protein levels, indicate that morphine induction of RGS4 could contribute to aspects of opiate tolerance and dependence displayed by LC neurons.Type of Medium: Electronic ResourceURL: -
11Zorbas, Yan G. ; Naexu, Konstantin A. ; Federenko, Youri F.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. It has been suggested that prolonged exposure to a rigorous bed rest regimen (hypokinesia) may induce greater serum carbohydrate and electrolyte changes in physically conditioned than unconditional subjects and that chronic hyperhydration may normalize or attenuate the development of these biochemical alterations in physically conditioned subjects.2. Serum carbohydrate and electrolyte changes were determined in 18 physically healthy male volunteers aged 19–24 years during 30 days of a rigorous bed rest regimen. The subjects were divided into three equal groups. The first g oup consisted of six unconditioned subjects with V̇o2 max of 44 mL/kg bodyweight/min, the second group consisted of six conditioned subjects with V̇o2 max of 69 mL/ kg bodyweight/ min and the third group consisted of six conditioned subjects with V̇o2 max of 69 mL/kg body weight/min who consumed daily an additional amount of 26 mL water/kg bodyweight and 0.10 mg sodium chloride/kg bodyweight.3. For the simulation of the hypokinetic effect all volunteers were kept under a rigorous bed rest regimen for 30 days. During the pre hypokinetic period of 15 days and during the bed rest period of 30 days the concentrations of cortsol, aldosterone, testosterone, tri-idothyronine (T3), thyroxine (total; T4), glucose, potassium, sodium and chloride were determined in blood serum of volunteers.4. During the bed rest period of 30 days serum carbohydrate and electrolyte changes were more pronounced in physically conditioned than unconditioned hypokinetic subjects. In physically conditioned hyperhydrated subjects serum carbohydrate and electrolyte changes were less pronounced than in physically conditioned and unconditioned hypokinetic subjects.5. It was concluded that exposure to a rigorous bed rest regimen over a prolonged period of time induced significantly more changes in serum carbohydrate and electrolyte concentrations in physically conditioned than in unconditioned subjects and that chronic hyperhydration may be used to normalize or stabilize all serum biochemical changes in physically conditioned subjects during prolonged exposure to a rigorous bed rest regimen.Type of Medium: Electronic ResourceURL: -
12Minassian, Berge A. ; Lee, Jeffrey R. ; Herbrick, Jo-Anne ; Huizenga, Jack ; Soder, Sylvia ; Mungall, Andrew J. ; Dunham, Ian ; Gardner, Rebecca ; Fong, Chung-yan G. ; Carpenter, Stirling ; Jardim, Laura ; Satishchandra, P. ; Andermann, Eva ; Snead, O. Carter ; Lopes-Cendes, Iscia ; Tsui, Lap-Chee ; Delgado-Escueta, Antonio V. ; Rouleau, Guy A. ; Scherer, Stephen W.
[s.l.] : Nature America Inc.
Published 1998Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] Lafora's disease (LD; OMIM 254780) is an autosomal recessive form of progressive myoclonus epilepsy characterized by seizures and cumulative neurological deterioration. Onset occurs during late childhood and usually results in death within ten years of the first symptoms1,2. With few exceptions, ...Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0022-3697Keywords: Anomalous scattering ; bismuth cuprate ; cation distribution ; high T"c superconductor ; selective atom diffractionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0022-3697Keywords: Superconductivity ; disorder ; ion beam mixing ; multilayer filmsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0003-2670Keywords: Fluorimetry ; IronSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0303-7207Keywords: Cyclic AMP response element binding protein ; Glial cell ; Prolactin gene ; Promoter activation ; Transfection ; VP16Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0038-1101Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsType of Medium: Electronic ResourceURL: -
18Qi-rui, Z. ; Yi-tai, Q. ; Zu-yao, C. ; Wei-yan, G. ; Yong, Z. ; Hang, Z. ; Lie-zhao, C. ; Jian-sheng, X. ; Min-hu, F. ; Zheng-hui, H. ; Guo-qiang, P. ; Shi-fang, S. ; Dao-qi, Y. ; Min-jian, Z. ; Tao, Z.
Amsterdam : ElsevierStaff ViewISSN: 0038-1098Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Hansch, T.W. ; Lyons, D.R. ; Schawlow, A.L. ; Siegel, A. ; Wang, Z.-Y. ; Yan, G.-Y.
Amsterdam : ElsevierStaff ViewISSN: 0030-4018Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
20Qi-rui, Z. ; Yi-tai, Q. ; Zu-yao, C. ; Wei-yan, G. ; Yong, Z. ; Han, Z. ; Lie-zhao, C. ; Jian-zheng, X. ; Ming-hu, F. ; Zheng-hui, H. ; Guo-gang, P. ; Shi-fang, S. ; Dao-qi, Y. ; Zhi-ping, Y. ; Ming-jian, Z. ; Tao, Z.
Amsterdam : ElsevierStaff ViewISSN: 0038-1098Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: