Search Results - (Author, Cooperation:G. Velasco)

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  1. 1
    X. S. Puente ; M. Pinyol ; V. Quesada ; L. Conde ; G. R. Ordonez ; N. Villamor ; G. Escaramis ; P. Jares ; S. Bea ; M. Gonzalez-Diaz ; L. Bassaganyas ; T. Baumann ; M. Juan ; M. Lopez-Guerra ; D. Colomer ; J. M. Tubio ; C. Lopez ; A. Navarro ; C. Tornador ; M. Aymerich ; M. Rozman ; J. M. Hernandez ; D. A. Puente ; J. M. Freije ; G. Velasco ; A. Gutierrez-Fernandez ; D. Costa ; A. Carrio ; S. Guijarro ; A. Enjuanes ; L. Hernandez ; J. Yague ; P. Nicolas ; C. M. Romeo-Casabona ; H. Himmelbauer ; E. Castillo ; J. C. Dohm ; S. de Sanjose ; M. A. Piris ; E. de Alava ; J. San Miguel ; R. Royo ; J. L. Gelpi ; D. Torrents ; M. Orozco ; D. G. Pisano ; A. Valencia ; R. Guigo ; M. Bayes ; S. Heath ; M. Gut ; P. Klatt ; J. Marshall ; K. Raine ; L. A. Stebbings ; P. A. Futreal ; M. R. Stratton ; P. J. Campbell ; I. Gut ; A. Lopez-Guillermo ; X. Estivill ; E. Montserrat ; C. Lopez-Otin ; E. Campo
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-06-07
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Carrier Proteins/genetics ; DNA Mutational Analysis ; Genome, Human/*genetics ; Humans ; Karyopherins/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/*genetics ; Molecular Sequence Data ; Mutation/*genetics ; Myeloid Differentiation Factor 88/chemistry/genetics ; Receptor, Notch1/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Reproducibility of Results
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background The collectin surfactant protein D (SP-D) confers protection against pulmonary infection and inflammation. Recent data suggest a role for SP-D in the modulation of allergic inflammation.Objective The aim of this study is to characterize the immune responses of SP-D-deficient (SP-D−/−) mice in a kinetic model of allergic inflammation. We determined whether allergic parameters were enhanced in SP-D−/− mice in vivo. Further, we examined whether functional immune responses in vitro such as lymphocyte proliferation (LP) and cytokine production were modulated in the absence of SP-D.Methods In vivo, wild-type (WT) and SP-D−/− mice were sensitized and challenged with the allergen ovalbumin (OVA) and assessed for allergic parameters (bronchoalveolar lavage (BAL) eosinophils, IL-13 production, pulmonary IFN-γ, IL-10 expression) at early time points (1 and 3 days of challenge) in comparison with late time points (7 days of challenge). In vitro, spleen cells from WT and SP-D−/− mice were stimulated with the mitogen concanavalin A (ConA) and lipid A (LpA) and analysed for LP, IL-13 and IFN-γ production. Toll-like receptor 4 (TLR4), ligand for LpA, was assessed by mRNA expression and immunohistochemistry in vivo.Results Following allergen exposure in vivo, SP-D−/− mice expressed higher BAL eosinophils and IL-13 concentrations and lower IFN-γ expression at early time points compared with WT mice. IL-10 expression was increased at early time points in SP-D−/− compared with WT mice. Allergen-induced TLR4 expression was increased in WT, but not in SP-D−/− mice. After stimulation with LpA and ConA in vitro LP was increased and IFN-γ concentration was decreased in SP-D−/− mice.Conclusion SP-D may be critical for the modulation of early stages of allergic inflammation in vivo.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2222.2004.02068.x

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] BB membrane; brush border membrane ; [abr] BL membrane; basolateral membrane ; [abr] EDTA; ethylene-diaminetetracetic acid ; [abr] EGTA; ethylene glycol bis ( β-aminoethylether)-N,N,N',N' ; [abr] Me"2 SO; dimethyl sulfoxide ; [abr] PI; phosphatidylinositol ; [abr] PKC; protein kinase C ; [abr] PS; phosphatidylserine ; [abr] PhMeSO"2 F; phenyl methylsulfonyl fluoride ; [abr] TPA; 12-tetradecanoylphorbol-13 acetate
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80259-5

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(85)90728-3

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80359-3

    Articles: DFG German National Licenses
  6. 6
    Guzman, M. ; Velasco, G. ; Castro, J. ; Zammit, V.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Carnitine palmitoyltransferase I ; Glutamine ; Hepatocyte swelling ; Ketogenesis
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(94)00405-6

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80359-3

    Articles: DFG German National Licenses
  8. 8
    Velasco, G. ; Shears, S.B. ; Michell, R.H. ; Lazo, P.S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] EDTA; ethilene-diaminetetraacetic acid ; [abr] EGTA; ethilene glycol bis (β -aminoethylether)-N,N,N',N', ; [abr] Ins(1,4,5); inositol(1,4,5)trisphosphate
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80034-1

    Articles: DFG German National Licenses
  9. 9
    Barros, F. ; Dominguez, P. ; Velasco, G. ; Lazo, P.S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80495-8

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] BB membrane; brush border membrane ; [abr] BL membrane; basolateral membrane ; [abr] EDTA; ethylene-diaminetetracetic acid ; [abr] EGTA; ethylene glycol bis ( β-aminoethylether)-N,N,N',N' ; [abr] Me"2 SO; dimethyl sulfoxide ; [abr] PI; phosphatidylinositol ; [abr] PKC; protein kinase C ; [abr] PS; phosphatidylserine ; [abr] PhMeSO"2 F; phenyl methylsulfonyl fluoride ; [abr] TPA; 12-tetradecanoylphorbol-13 acetate
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80259-5

    Articles: DFG German National Licenses
  11. 11
    Velasco, G. ; Shears, S.B. ; Michell, R.H. ; Lazo, P.S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] EDTA; ethilene-diaminetetraacetic acid ; [abr] EGTA; ethilene glycol bis (β -aminoethylether)-N,N,N',N', ; [abr] Ins(1,4,5); inositol(1,4,5)trisphosphate
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80034-1

    Articles: DFG German National Licenses
  12. 12
    Barros, F. ; Dominguez, P. ; Velasco, G. ; Lazo, P.S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(86)80495-8

    Articles: DFG German National Licenses
  13. 13
    Pribat, D. ; Velasco, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0250-6874
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0250-6874(88)80040-4

    Articles: DFG German National Licenses
  14. 14
    Velasco, G. ; Schnell, J.P. ; Croset, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0250-6874
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0250-6874(81)80057-1

    Articles: DFG German National Licenses
  15. 15
    Velasco, G. ; Dominguez, P. ; Shears, S.B. ; Lazo, P.S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-4889
    Keywords:
    (Rat small intestine) ; Enterocyte metabolism ; Enterocyte permeability ; Glucose metabolism
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-4889(86)90199-0

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0167-5087
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-5087(83)90937-7

    Articles: DFG German National Licenses
  17. 17
    Thi, M.P. ; Velasco, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-2738
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2738(84)90101-2

    Articles: DFG German National Licenses
  18. 18
    Schnell, P. ; Velasco, G. ; Colomban, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-2738
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2738(81)90250-2

    Articles: DFG German National Licenses
  19. 19
    Velasco, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-2738
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2738(83)90087-5

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0167-2738
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2738(83)90196-0

    Articles: DFG German National Licenses