Search Results - (Author, Cooperation:G. Sella)
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1Latest Papers from Table of Contents or Articles in PressR. D. Hernandez ; J. L. Kelley ; E. Elyashiv ; S. C. Melton ; A. Auton ; G. McVean ; G. Sella ; M. Przeworski
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-02-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Biological ; Amino Acid Substitution ; *Biological Evolution ; Chromosomes, Human, X/genetics ; Conserved Sequence ; Evolution, Molecular ; Exons ; Gene Frequency ; *Genetic Variation ; *Genome, Human ; Haplotypes ; Humans ; Models, Genetic ; Molecular Sequence Annotation ; Mutation ; Polymorphism, Single Nucleotide ; Recombination, Genetic ; *Selection, Genetic ; Untranslated RegionsPublished by: -
2Latest Papers from Table of Contents or Articles in PressE. M. Leffler ; Z. Gao ; S. Pfeifer ; L. Segurel ; A. Auton ; O. Venn ; R. Bowden ; R. Bontrop ; J. D. Wall ; G. Sella ; P. Donnelly ; G. McVean ; M. Przeworski
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-02-16Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; Genetic Association Studies ; Genome, Human/*genetics ; Haplotypes ; Host-Pathogen Interactions/*genetics ; Humans ; Molecular Sequence Data ; Pan troglodytes/*genetics ; Pedigree ; Polymorphism, Single Nucleotide ; *Selection, GeneticPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary In the Polychaete wormOphryotrocha diadema, the yellow coloration of egg yolk is due to the selective uptake of lutein from food. The genetic control of this mechanism depends on a single locus with 2 alleles, the dominantY (yellow) allele, and the recessivey (absence of coloration) allele.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1432-1793Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Chromosomal nucleolar organizer region (NOR) phenotypes have been characterized in nine species of the genus Ophryotrocha (Polychaeta: Dorvilleidae), namely O. notoglandulata, O. sp. macrovifera, O. sp. labronica pacifica, O. labronica labronica, O. puerilis puerilis, O. diadema, O. sp. robusta, O. gracills and O. hartmanni. Irrespective of chromosome number and morphology, Ag positive regions were terminally located in all but one species, O. diadema, where the NORs were pericentromerical in a metacentric pair. The presence of a single chromosome pair bearing NOR in invertebrates is considered an ancestral trait. According to this assumption, O. sp. robusta, O. dialema, and perhaps O. p. puerilis appear to be more ancestral than the other species. On the contrary, O. notoglandulaia, O. sp. macrovifera, O. sp. labronica oacifica, with two chromosomal pairs bearing NOR sites, seem to represent examples of further evolution within the genus Ophryotrocha.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-1793Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Patella caerulea L., P. aspera Lam. (=P. ulyssiponensis Gmelin). P. rustica L. (=P. lusitanica Gmelin) are coexisting Mediterranean species of the genus Patella. P. caerulea and P. rustica have a haploid complement of n=9 with seven metacentric and two telocentric chromosomes, while P. aspera has a haploid complement of n=8 without telocentric chromosomes. To better define the phylogenetic relationships among these three species, an electrophoretic analysis of 12 enzyme coding loci was performed on samples of the three species collected from Laigueglia (Liguria, Italy) in 1989. On the whole, genotypic frequencies were in agreement with Hardy-Weinberg expectations and no significant differences were observed among the populations of the three species as far as their genetic structure is concerned. Nearly 50% of the sampled loci were diagnostic. Nei's genetic distance was 0.82 between P. caerulea and P. aspera, 0.97 between P. aspera and P. rustica and 0.94 between P. caerulea and P. rustica. By greatly separating P. rustica from the other two species, results of the electrophoretic analysis are consistent with the traditional view, which regards P. aspera and P. caerulea as more closely related than P. rustica on the basis of radular teeth morphology. Using genetic distances and the assumptions of the molecular clock, lineages leading to P. aspera and to P. caerulea may have diverged from the stem common to P. rustica ca. 18 million years ago.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1573-6857Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Differences in karyotypic structure are compared with reported isozyme differences in three Mediterranean species of Patella. In addition, the karyotypic structure of Patella is discussed in terms of the karyotypic variability of Archaeogastropoda. Both P. lusitanica and P. caerulea have a haploid complement of n=9 (6 metacentric, 1 submetacentric, 1 subtelocentric, 1 telocentric chromosome in P. lusitanica and 6 metacentric, 1 submetacentric, 2 telocentric chromosome in P. caerulea). P. aspera, although regarded as morphologically more closely related to P. caerulea, has a haploid complement of only n=8 (7 metacentric and 1 submetacentric chromosomes).Type of Medium: Electronic ResourceURL: