Search Results - (Author, Cooperation:G. R. Bignell)
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1Latest Papers from Table of Contents or Articles in PressP. J. Stephens ; P. S. Tarpey ; H. Davies ; P. Van Loo ; C. Greenman ; D. C. Wedge ; S. Nik-Zainal ; S. Martin ; I. Varela ; G. R. Bignell ; L. R. Yates ; E. Papaemmanuil ; D. Beare ; A. Butler ; A. Cheverton ; J. Gamble ; J. Hinton ; M. Jia ; A. Jayakumar ; D. Jones ; C. Latimer ; K. W. Lau ; S. McLaren ; D. J. McBride ; A. Menzies ; L. Mudie ; K. Raine ; R. Rad ; M. S. Chapman ; J. Teague ; D. Easton ; A. Langerod ; M. T. Lee ; C. Y. Shen ; B. T. Tee ; B. W. Huimin ; A. Broeks ; A. C. Vargas ; G. Turashvili ; J. Martens ; A. Fatima ; P. Miron ; S. F. Chin ; G. Thomas ; S. Boyault ; O. Mariani ; S. R. Lakhani ; M. van de Vijver ; L. van 't Veer ; J. Foekens ; C. Desmedt ; C. Sotiriou ; A. Tutt ; C. Caldas ; J. S. Reis-Filho ; S. A. Aparicio ; A. V. Salomon ; A. L. Borresen-Dale ; A. L. Richardson ; P. J. Campbell ; P. A. Futreal ; M. R. Stratton
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Age Factors ; Breast Neoplasms/classification/*genetics/pathology ; Cell Transformation, Neoplastic/*genetics ; Cytosine/metabolism ; DNA Mutational Analysis ; Female ; Humans ; JNK Mitogen-Activated Protein Kinases/metabolism ; Mutagenesis/*genetics ; Mutation/*genetics ; Neoplasm Grading ; Oncogenes/*genetics ; Reproducibility of Results ; Signal Transduction/geneticsPublished by: -
2Latest Papers from Table of Contents or Articles in PressM. J. Garnett ; E. J. Edelman ; S. J. Heidorn ; C. D. Greenman ; A. Dastur ; K. W. Lau ; P. Greninger ; I. R. Thompson ; X. Luo ; J. Soares ; Q. Liu ; F. Iorio ; D. Surdez ; L. Chen ; R. J. Milano ; G. R. Bignell ; A. T. Tam ; H. Davies ; J. A. Stevenson ; S. Barthorpe ; S. R. Lutz ; F. Kogera ; K. Lawrence ; A. McLaren-Douglas ; X. Mitropoulos ; T. Mironenko ; H. Thi ; L. Richardson ; W. Zhou ; F. Jewitt ; T. Zhang ; P. O'Brien ; J. L. Boisvert ; S. Price ; W. Hur ; W. Yang ; X. Deng ; A. Butler ; H. G. Choi ; J. W. Chang ; J. Baselga ; I. Stamenkovic ; J. A. Engelman ; S. V. Sharma ; O. Delattre ; J. Saez-Rodriguez ; N. S. Gray ; J. Settleman ; P. A. Futreal ; D. A. Haber ; M. R. Stratton ; S. Ramaswamy ; U. McDermott ; C. H. Benes
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cell Survival/drug effects ; Drug Resistance, Neoplasm/drug effects/*genetics ; *Drug Screening Assays, Antitumor ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Neoplasm/*genetics ; Genetic Markers/*genetics ; Genome, Human/*genetics ; Genomics ; Humans ; Indoles/pharmacology ; Neoplasms/*drug therapy/*genetics/pathology ; Oncogene Proteins, Fusion/genetics ; Pharmacogenetics ; Phthalazines/pharmacology ; Piperazines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors ; Proto-Oncogene Protein c-fli-1/genetics ; RNA-Binding Protein EWS/genetics ; Sarcoma, Ewing/drug therapy/genetics/pathologyPublished by: -
3Latest Papers from Table of Contents or Articles in PressL. B. Alexandrov ; S. Nik-Zainal ; D. C. Wedge ; S. A. Aparicio ; S. Behjati ; A. V. Biankin ; G. R. Bignell ; N. Bolli ; A. Borg ; A. L. Borresen-Dale ; S. Boyault ; B. Burkhardt ; A. P. Butler ; C. Caldas ; H. R. Davies ; C. Desmedt ; R. Eils ; J. E. Eyfjord ; J. A. Foekens ; M. Greaves ; F. Hosoda ; B. Hutter ; T. Ilicic ; S. Imbeaud ; M. Imielinski ; N. Jager ; D. T. Jones ; D. Jones ; S. Knappskog ; M. Kool ; S. R. Lakhani ; C. Lopez-Otin ; S. Martin ; N. C. Munshi ; H. Nakamura ; P. A. Northcott ; M. Pajic ; E. Papaemmanuil ; A. Paradiso ; J. V. Pearson ; X. S. Puente ; K. Raine ; M. Ramakrishna ; A. L. Richardson ; J. Richter ; P. Rosenstiel ; M. Schlesner ; T. N. Schumacher ; P. N. Span ; J. W. Teague ; Y. Totoki ; A. N. Tutt ; R. Valdes-Mas ; M. M. van Buuren ; L. van 't Veer ; A. Vincent-Salomon ; N. Waddell ; L. R. Yates ; J. Zucman-Rossi ; P. A. Futreal ; U. McDermott ; P. Lichter ; M. Meyerson ; S. M. Grimmond ; R. Siebert ; E. Campo ; T. Shibata ; S. M. Pfister ; P. J. Campbell ; M. R. Stratton
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/genetics ; Algorithms ; Cell Transformation, Neoplastic/*genetics/pathology ; Cytidine Deaminase/genetics ; DNA/genetics/metabolism ; DNA Mutational Analysis ; Humans ; Models, Genetic ; Mutagenesis/*genetics ; Mutagenesis, Insertional/genetics ; Mutagens/pharmacology ; Mutation/*genetics ; Neoplasms/enzymology/*genetics/pathology ; Organ Specificity ; Reproducibility of Results ; Sequence Deletion/genetics ; Transcription, Genetic/geneticsPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 1432-0983Keywords: Key wordsLipomyces starkeyi ; Electrophoretic karyotype ; CHEF ; TRP1Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The genome of the amylolytic yeast strain Lipomyces starkeyi NCYC 1436 was analysed using contour-clamped homogeneous electric field gel electrophoresis (CHEF). The banding pattern under a variety of running conditions indicating the presence of 11 different chromosome-sized DNA molecules. The sizes of these chromosome bands were determined by comparison with chromosomes from standard strains of Schizosaccharomyces pombe and Saccharomyces cerevisiae. The chromosomal bands were estimated to be within the range 0.7–2.8 Mb, with the genome (excluding mitochondrial DNA) estimated at 15 Mb. The molecular cloning of the TRP1 gene, isolated from a genomic library of this strain, is also reported: the gene was present on a 6.5-kb Sau3A DNA fragment, and complemented the trpC gene of E. coli. The DNA sequence was determined (EMBL accession No. Z68292) and compared to other tryptophan biosynthetic genes encoding N-(5′-phosphoribosyl) anthranilate isomerase (PRAI) activity. The gene was also used as a probe in hybridization studies, and by this means, its chromosomal location was identified.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1572-9699Keywords: glucoamylase ; STA ; PFGE ; CHEFSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The chromosomal locations of four glucoamylase-specifying genes in the yeastSaccharomyces cerevisiae have been determined. Chromosomes were separated by pulsed field gel electrophoresis and blots were probed with radiolabelledSTA2 and marker DNA from specific yeast chromosomes. The three genes encoding extracellular glucoamylases,STA1 (DEX2), STA2 (DEX1) andSTA3 (DEX3) are located on chromosomes IV, II and XIV, respectively.SGA, specifying the sporulation-specific glucoamylase, was positioned on chromosome IX.Type of Medium: Electronic ResourceURL: