Search Results - (Author, Cooperation:G. Nunez)

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  1. 1
    N. Kamada ; Y. G. Kim ; H. P. Sham ; B. A. Vallance ; J. L. Puente ; E. C. Martens ; G. Nunez
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-05-15
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacterial Load ; Bacterial Proteins/genetics/metabolism ; Bacteroides/*growth & development ; Citrobacter rodentium/genetics/growth & development/immunology/*pathogenicity ; Enterobacteriaceae Infections/immunology/*microbiology ; Escherichia coli/*growth & development ; Feces/microbiology ; Gene Expression Regulation, Bacterial ; Germ-Free Life ; Intestinal Mucosa/*microbiology ; Intestines/*microbiology ; *Metagenome ; Mice ; Mice, Inbred C57BL ; *Microbial Interactions ; Specific Pathogen-Free Organisms ; Virulence Factors/genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    L. Franchi ; G. Nunez
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-09-18
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; CARD Signaling Adaptor Proteins/genetics/*metabolism ; Calcium-Binding Proteins/genetics/*metabolism ; Enzyme Activation ; Gram-Negative Bacteria/*immunology ; Gram-Negative Bacterial Infections/enzymology/*immunology ; Humans ; Inflammasomes/*metabolism ; Mice ; Mice, Mutant Strains ; Mutation ; Phosphorylation ; Protein Kinase C-delta/*metabolism ; Serine/genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Y. He ; M. Y. Zeng ; D. Yang ; B. Motro ; G. Nunez
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-01-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Apoptosis Regulatory Proteins/deficiency/genetics/metabolism ; Biocatalysis ; Carrier Proteins/chemistry/genetics/*metabolism ; Caspase 1/metabolism ; Catalytic Domain ; Cells, Cultured ; Cryopyrin-Associated Periodic Syndromes/genetics ; Enzyme Activation ; HEK293 Cells ; Humans ; Inflammasomes/*chemistry/*metabolism ; Interleukin-1beta/secretion ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Potassium/*metabolism ; Protein Binding ; Protein Multimerization ; Protein-Serine-Threonine Kinases/chemistry/deficiency/genetics/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2013-11-01
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacterial Toxins/*metabolism/pharmacology ; Calcium Signaling/drug effects ; *Cell Degranulation/drug effects ; Culture Media, Conditioned/pharmacology ; Dermatitis, Atopic/immunology/metabolism/*microbiology/pathology ; Female ; Immunoglobulin E/biosynthesis/immunology ; Inflammation/immunology/metabolism/microbiology/pathology ; Interleukin-4/immunology ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mast Cells/*cytology/drug effects ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins c-kit/genetics/metabolism ; Staphylococcus aureus/metabolism/*pathogenicity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Hu, Y., Song, F., Jiang, H., Nunez, G., Smith, D. E.
    The American Association of Immunologists (AAI)
    Published 2018
    Staff View
    Publication Date:
    2018-07-10
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Nunez, G., Sakamoto, K., Soares, M. P.
    The American Association of Immunologists (AAI)
    Published 2018
    Staff View
    Publication Date:
    2018-06-19
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    NUNEZ, G. ; UGOLINI, V. ; CAPRA, J. D. ; STASTNY, P.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1982
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Three monoclonal antibodies (63D3, 63D2, and 61D3) with reactivity against human monocytes have been studied. They reacted with most adherent mononuclear cells but not with pure populations of peripheral blood B and T lymphocytes. Two of these antibodies, 63D3 and 63D2, competed in fluorescence inhibition experiments, recognized a monocyte surface antigem of about 200,000 daltons, and werre idiotypically related. The third antibody, 61D3, did not compete with the others in fluorescence inhibition experiments, recognized a different surface molecule, and was idiotypically distinct from 63D3 and 63D2. Whereas 63D3 and 63D2 reacted very weakly with some granulucytes, 61D3 did not, suggesting that it is specific for monocytes alone.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Nunez, G. ; Clarke, M.F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0962-8924
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Núñez, G.

    Madrid : Periodicals Archive Online (PAO)
    Published 1968
    Staff View
    ISSN:
    0013-6662
    Topics:
    Classical Studies
    Description / Table of Contents:
    LINGUISTICA
    Notes:
    Reseñas de libros
    URL:
    Articles: DFG German National Licenses
  10. 10
    NÚÑEZ, G.

    Madrid : Periodicals Archive Online (PAO)
    Published 1969
    Staff View
    ISSN:
    0013-6662
    Topics:
    Classical Studies
    Description / Table of Contents:
    LITERATURA, HISTORIA, FILOSOFIA
    Notes:
    Reseñas de libros
    URL:
    Articles: DFG German National Licenses
  11. 11
    NÚÑEZ, G.

    Madrid : Periodicals Archive Online (PAO)
    Published 1969
    Staff View
    ISSN:
    0013-6662
    Topics:
    Classical Studies
    Description / Table of Contents:
    RESEÑAS BREVES
    Notes:
    Reseñas de libros
    URL:
    Articles: DFG German National Licenses
  12. 12
    Núñez, G.

    Madrid : Periodicals Archive Online (PAO)
    Published 1970
    Staff View
    ISSN:
    0013-6662
    Topics:
    Classical Studies
    Description / Table of Contents:
    LITERATURA, HISTORIA, FILOSOFIA
    Notes:
    Reseñas de libros
    URL:
    Articles: DFG German National Licenses
  13. 13
  14. 14
  15. 15
    Nunez, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-5419
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Technology
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    NÚÑEZ, G.

    Madrid : Periodicals Archive Online (PAO)
    Published 1941
    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    1432-1203
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Hb Lepore is one of the most common abnormal haemoglobins in Caucasians in Central Portugal and in the Spanish Alta Extremadura (0.28% in a survey of school children). A group of 19 Portuguese and 14 Spanish Hb Lepore carriers (all unrelated) was characterised at the molecular level by the polymerase chain reaction, sequencing and restriction enzyme analysis. The Portuguese and one Spanish carrier were heterozygous for Hb Lepore-Baltimore, whereas all other Spanish subjects were Hb Lepore-Washington-Boston carriers. Sequencing of the Hb Lepore-Baltimore gene further established the crossover at δ68-β84, a region two codons (CDs) shorter than that previously described and easily confirmed by digestion with MaeI and BanI. Data from haplotype analysis suggest that this crossover occurred as an independent event on the lberian Peninsula. The haematological data were similar in both groups except for the levels of Hb F and the Gγ chain, which were significantly higher in the Hb Lepore-Baltimore heterozygotes. Quantification of the globin chains and the mRNA transcripts showed that the δβ gene is transcribed at a higher level than the δ gene with levels of translation giving rise to 10%–15% of Hb Lepore. The different levels of Hb F observed in the two groups are the results of the higher transcription rate of the γ genes in Hb Lepore-Baltimore heterozygotes and an apparently less efficient translation of Gγ genes in Hb Lepore-Washington-Boston heterozygotes.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1432-1955
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Antisurface newborn larva (NBL) antibodies (Abs) were found in sera from individuals chronically infected with Trichinella spiralis. These Abs were incapable of inducing NBL death by activation of normal human leukocytes of peripheral blood as determined by in vitro assays of antibody-dependent cell cytotoxicity (ADCC). Besides, such sera blocked the cytotoxic reaction mediated by Abs produced a few weeks after infection. The blocking activity could not be attributed to any particular isotype by the indirect immunofluorescence technique. Purified antisurface NBL Abs obtained from sera from chronically infected patients recognized antigens of muscle-larva excretory-secretory products (ML-ESP) in an enzyme-linked immunosorbent assay (ELISA) and an immunoelectrotransfer blot assay. Likewise, as did chronic sera, a monoclonal Ab raised against ML-ESP blocked NBL death in ADCC assays. These results suggest that during the course of an infection by T. spiralis, Abs related to ML-ESP provide an immunoevasive mechanism for avoidance by NBL of an important anti-NBL host effector mechanism.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Nuñez, G. M. ; Rouco, A. J.
    Springer
    Published 1986
    Staff View
    ISSN:
    1588-2837
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Abstract После обработки водородом при высокой температуре наблюдалось уменьшение водородной хемосорбции при комнатной температуре почти для всех элементов VIII группы, нанесенных на SiO2 или Al2O3. Этот эффект приписывается самоингибированию сильно хемосорбированного водорода на металлах.
    Notes:
    Abstract Following hydrogen treatments at high temperature a decrease in hydrogen chemisorption at room temperature is observed in almost all group VIII elements supported on SiO2 or Al2O3. The effect is attributed to self inhibition by strongly chemisorbed hydrogen on the metals.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses