Search Results - (Author, Cooperation:G. Nunez)
-
1N. Kamada ; Y. G. Kim ; H. P. Sham ; B. A. Vallance ; J. L. Puente ; E. C. Martens ; G. Nunez
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-05-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Load ; Bacterial Proteins/genetics/metabolism ; Bacteroides/*growth & development ; Citrobacter rodentium/genetics/growth & development/immunology/*pathogenicity ; Enterobacteriaceae Infections/immunology/*microbiology ; Escherichia coli/*growth & development ; Feces/microbiology ; Gene Expression Regulation, Bacterial ; Germ-Free Life ; Intestinal Mucosa/*microbiology ; Intestines/*microbiology ; *Metagenome ; Mice ; Mice, Inbred C57BL ; *Microbial Interactions ; Specific Pathogen-Free Organisms ; Virulence Factors/genetics/metabolismPublished by: -
2Staff View
Publication Date: 2012-09-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CARD Signaling Adaptor Proteins/genetics/*metabolism ; Calcium-Binding Proteins/genetics/*metabolism ; Enzyme Activation ; Gram-Negative Bacteria/*immunology ; Gram-Negative Bacterial Infections/enzymology/*immunology ; Humans ; Inflammasomes/*metabolism ; Mice ; Mice, Mutant Strains ; Mutation ; Phosphorylation ; Protein Kinase C-delta/*metabolism ; Serine/genetics/metabolismPublished by: -
3Staff View
Publication Date: 2016-01-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Apoptosis Regulatory Proteins/deficiency/genetics/metabolism ; Biocatalysis ; Carrier Proteins/chemistry/genetics/*metabolism ; Caspase 1/metabolism ; Catalytic Domain ; Cells, Cultured ; Cryopyrin-Associated Periodic Syndromes/genetics ; Enzyme Activation ; HEK293 Cells ; Humans ; Inflammasomes/*chemistry/*metabolism ; Interleukin-1beta/secretion ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Potassium/*metabolism ; Protein Binding ; Protein Multimerization ; Protein-Serine-Threonine Kinases/chemistry/deficiency/genetics/*metabolismPublished by: -
4Y. Nakamura ; J. Oscherwitz ; K. B. Cease ; S. M. Chan ; R. Munoz-Planillo ; M. Hasegawa ; A. E. Villaruz ; G. Y. Cheung ; M. J. McGavin ; J. B. Travers ; M. Otto ; N. Inohara ; G. Nunez
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Toxins/*metabolism/pharmacology ; Calcium Signaling/drug effects ; *Cell Degranulation/drug effects ; Culture Media, Conditioned/pharmacology ; Dermatitis, Atopic/immunology/metabolism/*microbiology/pathology ; Female ; Immunoglobulin E/biosynthesis/immunology ; Inflammation/immunology/metabolism/microbiology/pathology ; Interleukin-4/immunology ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mast Cells/*cytology/drug effects ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins c-kit/genetics/metabolism ; Staphylococcus aureus/metabolism/*pathogenicityPublished by: -
5Hu, Y., Song, F., Jiang, H., Nunez, G., Smith, D. E.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-07-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
6Nunez, G., Sakamoto, K., Soares, M. P.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-06-19Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
7NUNEZ, G. ; UGOLINI, V. ; CAPRA, J. D. ; STASTNY, P.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Three monoclonal antibodies (63D3, 63D2, and 61D3) with reactivity against human monocytes have been studied. They reacted with most adherent mononuclear cells but not with pure populations of peripheral blood B and T lymphocytes. Two of these antibodies, 63D3 and 63D2, competed in fluorescence inhibition experiments, recognized a monocyte surface antigem of about 200,000 daltons, and werre idiotypically related. The third antibody, 61D3, did not compete with the others in fluorescence inhibition experiments, recognized a different surface molecule, and was idiotypically distinct from 63D3 and 63D2. Whereas 63D3 and 63D2 reacted very weakly with some granulucytes, 61D3 did not, suggesting that it is specific for monocytes alone.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0962-8924Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0013-6662Topics: Classical StudiesDescription / Table of Contents: LINGUISTICANotes: Reseñas de librosURL: -
10Staff View
ISSN: 0013-6662Topics: Classical StudiesDescription / Table of Contents: LITERATURA, HISTORIA, FILOSOFIANotes: Reseñas de librosURL: -
11Staff View
ISSN: 0013-6662Topics: Classical StudiesDescription / Table of Contents: RESEÑAS BREVESNotes: Reseñas de librosURL: -
12Staff View
ISSN: 0013-6662Topics: Classical StudiesDescription / Table of Contents: LITERATURA, HISTORIA, FILOSOFIANotes: Reseñas de librosURL: -
13Staff View
ISSN: 0013-6662Topics: Classical StudiesDescription / Table of Contents: LINGUISTICANotes: Reseñas de librosURL: -
14Staff View
ISSN: 0013-6662Topics: Classical StudiesNotes: LINGUISTICAURL: -
15Staff View
ISSN: 0167-5419Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: TechnologyEconomicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0018-2141Topics: HistoryNotes: INFORMACIONURL: -
17Ribeiro, M. L. ; Cunha, E. ; Gonçalves, P. ; Núñez, G. Martin ; Galan, M. A. Fernandez ; Tamagnini, G. P. ; Smetanina, N. S. ; Gu, L. H. ; Huisman, T. H. J.
Springer
Published 1997Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Hb Lepore is one of the most common abnormal haemoglobins in Caucasians in Central Portugal and in the Spanish Alta Extremadura (0.28% in a survey of school children). A group of 19 Portuguese and 14 Spanish Hb Lepore carriers (all unrelated) was characterised at the molecular level by the polymerase chain reaction, sequencing and restriction enzyme analysis. The Portuguese and one Spanish carrier were heterozygous for Hb Lepore-Baltimore, whereas all other Spanish subjects were Hb Lepore-Washington-Boston carriers. Sequencing of the Hb Lepore-Baltimore gene further established the crossover at δ68-β84, a region two codons (CDs) shorter than that previously described and easily confirmed by digestion with MaeI and BanI. Data from haplotype analysis suggest that this crossover occurred as an independent event on the lberian Peninsula. The haematological data were similar in both groups except for the levels of Hb F and the Gγ chain, which were significantly higher in the Hb Lepore-Baltimore heterozygotes. Quantification of the globin chains and the mRNA transcripts showed that the δβ gene is transcribed at a higher level than the δ gene with levels of translation giving rise to 10%–15% of Hb Lepore. The different levels of Hb F observed in the two groups are the results of the higher transcription rate of the γ genes in Hb Lepore-Baltimore heterozygotes and an apparently less efficient translation of Gγ genes in Hb Lepore-Washington-Boston heterozygotes.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1432-1955Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Antisurface newborn larva (NBL) antibodies (Abs) were found in sera from individuals chronically infected with Trichinella spiralis. These Abs were incapable of inducing NBL death by activation of normal human leukocytes of peripheral blood as determined by in vitro assays of antibody-dependent cell cytotoxicity (ADCC). Besides, such sera blocked the cytotoxic reaction mediated by Abs produced a few weeks after infection. The blocking activity could not be attributed to any particular isotype by the indirect immunofluorescence technique. Purified antisurface NBL Abs obtained from sera from chronically infected patients recognized antigens of muscle-larva excretory-secretory products (ML-ESP) in an enzyme-linked immunosorbent assay (ELISA) and an immunoelectrotransfer blot assay. Likewise, as did chronic sera, a monoclonal Ab raised against ML-ESP blocked NBL death in ADCC assays. These results suggest that during the course of an infection by T. spiralis, Abs related to ML-ESP provide an immunoevasive mechanism for avoidance by NBL of an important anti-NBL host effector mechanism.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1588-2837Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Abstract После обработки водородом при высокой температуре наблюдалось уменьшение водородной хемосорбции при комнатной температуре почти для всех элементов VIII группы, нанесенных на SiO2 или Al2O3. Этот эффект приписывается самоингибированию сильно хемосорбированного водорода на металлах.Notes: Abstract Following hydrogen treatments at high temperature a decrease in hydrogen chemisorption at room temperature is observed in almost all group VIII elements supported on SiO2 or Al2O3. The effect is attributed to self inhibition by strongly chemisorbed hydrogen on the metals.Type of Medium: Electronic ResourceURL: