Search Results - (Author, Cooperation:G. M. Lathrop)
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1Latest Papers from Table of Contents or Articles in PressL. Liang ; S. A. Willis-Owen ; C. Laprise ; K. C. Wong ; G. A. Davies ; T. J. Hudson ; A. Binia ; J. M. Hopkin ; I. V. Yang ; E. Grundberg ; S. Busche ; M. Hudson ; L. Ronnblom ; T. M. Pastinen ; D. A. Schwartz ; G. M. Lathrop ; M. F. Moffatt ; W. O. Cookson
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adolescent ; Adult ; Asthma/blood/genetics ; Child ; CpG Islands/genetics ; DNA Methylation/*genetics ; Eosinophils/cytology/metabolism ; Epigenesis, Genetic/*genetics ; Female ; *Genetic Association Studies ; Genome, Human/*genetics ; Humans ; Immunoglobulin E/*blood ; Inflammation Mediators ; Male ; Middle Aged ; Mitochondrial Proteins/genetics ; Pedigree ; Polymorphism, Single Nucleotide/genetics ; Transcription Factors/genetics ; Young AdultPublished by: -
2Articles: DFG German National LicensesHilbert, P. ; Lindpaintner, K. ; Beckmann, J. S. ; Serikawa, T. ; Soubrier, F. ; Dubay, C. ; Cartwright, P. ; Gouyon, B. De ; Julier, C. ; Takahasi, S. ; Vincent, M. ; Ganten, D. ; Georges, M. ; Lathrop, G. M.
[s.l.] : Nature Publishing Group
Published 1991Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The spontaneously hypertensive rat and the stroke-prone spontaneously hypertensive rat are useful models for human hypertension. In these strains hypertension is a polygenic trait, in which both autosomal and sex-linked genes can influence blood pressure1–7. Linkage studies in ...Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesHashimoto, L. ; Habita, C. ; Beressi, J. P. ; Delepine, M. ; Basse, C. ; Cambon-Thomsen, A. ; Deschamps, I. ; Rotter, J. I. ; Djoulah, S. ; James, M. R. ; Froguel, P. ; Weissenbach, J. ; Lathrop, G. M. ; Julier, C.
[s.l.] : Nature Publishing Group
Published 1994Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A panel of 314 Caucasian IDDM-affected sibling pairs from 231 families of French, American and North African origin was assembled for linkage studies. Initially, we characterized 321 markers (247 comprising an index map and 74 others from speci-fic regions of interest) in a sub-panel of 61 affected ...Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesJulier, C. ; Hyer, R. N. ; Davies, J. ; Merlin, F. ; Soularue, P. ; Briant, L. ; Cathelineau, G. ; Deschamps, I. ; Rotter, J. I. ; Froguel, P. ; Boitard, C. ; Bell, J. I. ; Lathrop, G. M.
[s.l.] : Nature Publishing Group
Published 1991Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] FIG. 1 Map of polymorphisms of INS and surrounding loci (o, characterized in isolated diabetics and controls; o, characterized in multiplex families), and primers used for sequencing. The placement of polymorphisms is derived from Cox et al.24, or Bell and Seino25, or deduced from ...Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesFroguel, Ph. ; Vaxillaire, M. ; Sun, F. ; Velho, G. ; Zouali, H. ; Butel, M. O. ; Lesage, S. ; Vionnet, N. ; Clément, K. ; Fougerousse, F. ; Tanizawa, Y. ; Weissenbach, J. ; Beckmann, J. S. ; Lathrop, G. M. ; Passa, Ph. ; Permutt, M. A. ; Cohen, D.
[s.l.] : Nature Publishing Group
Published 1992Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Although clinical and metabolic profiles of families with maturity-onset diabetes of the young (MODY) are diverse5, most MODY patients present a decreased insulin response to glucose, suggesting a primary pancreatic /3-cell defect6. Genes whose products seem to be involved in insulin secretion ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary We reconsider the method of Ott and Falk (1982) for the analysis of genetic linkage and of epistasis in the presence of phenotypic association. Their approach is extended to allow for gametic disequilibrium between marker and trait loci. We show that epistasis and tight linkage with gametic disequilibrium may be indistinguishable as explanations of association even in a very large pedigree.Type of Medium: Electronic ResourceURL: