Search Results - (Author, Cooperation:G. Grossmann)

2014-05-17

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

Arabidopsis/genetics/*metabolism ; Arabidopsis Proteins/genetics/*metabolism ; Cell Membrane/*metabolism ; Membrane Proteins/genetics/*metabolism ; *Protein Interaction Maps ; Signal Transduction ; Two-Hybrid System Techniques

article

2002

Bildungsgeschichte ; Bildungsgang ; Schulbesuch ; Schulgeschichte ; Gymnasium ; Geschichte (Histor) ; Berufslaufbahn ; 19. Jahrhundert ; 20. Jahrhundert ; Erlebnisbericht ; Kunsthistoriker ; Marburg

Zukunft braucht Erfahrung. Eine Festschrift. 475 Jahre Gymnasium Philippinum. [1527 - 2002]., Marburg: Gymnasium Philippinum (2002), S. 161-167

German

article

2013

Bildungsgeschichte ; Burg ; Geschichte (Histor) ; Gebäude ; Jugendbewegung ; 20. Jahrhundert ; Unterkunft ; Nerother Wandervogel ; Wandervogel ; Ludwigstein ; Rothenfels ; Waldeck

Stambolis, Barbara (Hrsg.), Aufbruch der Jugend. Deutsche Jugendbewegung zwischen Selbstbestimmung und Verführung. [Ausstellung im Germanischen Nationalmuseum, Nürnberg, 26. September bis 19. Januar 2014]., Nürnberg: Germanisches Nationalmuseum (2013), S. 82-91, 978-3-936688-77-1

German

0022-2828

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0022-2364

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0022-2364

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0034-5687

First breath ; Lung mechanics ; Neonatal lung adaptation ; Newborn rabbits ; Spontaneous ventilation

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0034-5687

Development ; Lung water ; Mammals ; Mechanics of breathing ; Surfactant ; amiloride ; compliance ; immature lung ; lung water resorption ; rabbit ; resorption ; surfactant

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0034-5687

Alveolus ; Epithelium ; Immaturity ; Lung ; Newborn ; Protein ; Pulmonary epithelium ; Rabbit ; Surfactant

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0034-5687

Artificial ventillation ; Immaturity ; Lung surfactant ; Newborn ; Protein leakage

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0038-1098

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0038-1098

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0009-2614

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Physics

Electronic Resource

0009-2614

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Physics

Electronic Resource

0378-4363

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

1435-1536

Red blood cell ; dextran ; macromolecular bridging ; gel permeation chromatography ; light scattering

Springer Online Journal Archives 1860-2000

Chemistry and Pharmacology

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Abstract B 512 F dextran fractions of different polydispersities were prepared by fractionnal precipitation and preparative elution chromatography. By combination of low angle laser light scattering (LALLS) and gel permeation chromatography (GPC), absolute average molecular weights (MWs) and molecular weight distribution functions (MWDs) were determined. Static and thermodynamical properties in terms of polymer dimensions and second virial coefficient of dilute solutions of dextran in water have been investigated. The results indicate that dextran macromolecules in water are rather compact and impenetrable coils. Measuring the disaggregation shear stress of dextran-induced red blood cell aggregates by laser light reflectometry, the macromolecular bridging energy was shown to depend upon dextran sample polydispersity. This reflects the weak and reversible character of red blood cell aggregation by dextran chains in physiological saline solution.

Electronic Resource

1432-1440

Diabetic cardiopathy ; Radionuclide Ventriculography

Springer Online Journal Archives 1860-2000

Medicine

Summary Left ventricular function was assessed by means of radionuclide ventriculography in 42 patients with long-standing (13±5 yrs) insulin-dependent diabetes mellitus and in eleven healthy age matched control subjects. Only diabetics were included in the study without diabetes related cardiac risk factors such as hypertension and CAD in order to evaluate diabetes specific changes of cardiac function. No differences were seen between diabetics and controls concerning heart rate and functional parameters of left ventricle in systole and diastole. The rapid filling period was not prolonged. According to our radionuclide data there is no evidence of diabetes related impairment of ventricular function in young patients with long-standing type-1-diabetes mellitus.

Electronic Resource

1432-0681

Springer Online Journal Archives 1860-2000

Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Zusammenfassung In der vorliegenden Arbeit wurde die experimentelle Durchführung des hydrodynamischen Torsionsgleichnisses von Pestel beschrieben. Es beruht auf der Gleichheit der Differentialgleichung für die schleichende Strömung und für die de St. Venantsche Torsion. Der Vorteil dieser Analogie besteht einmal darin, daß man Torsionswiderstand und Torsionsspannungen unabhängig für sich, jeweils in der dafür günstigsten Art und Weise bestimmen kann. Zum anderen ist der Aufwand an Geräten und an Rechnungsarbeit sehr gering. Für die Auswertung der experimentellen Ergebnisse bei der Ermittlung des Torsionswiderstandes wurde ein Diagramm entwickelt. Sowohl bei der Torsionswiderstandsbestimmung wie auch bei der Spannungsermittlung wurde eine für technische Zwecke ausreichende Genauigkeit erzielt. Vergleichsmessungen an Flächen mit bekannten Kenngrößen (J D,τ), die beim Prandtlschen Gleichnis z. B. in der Reichenbächer-Apparatur noch nötig sind, erübrigen sich in diesem Fall. Der Torsionswiderstand läßt sich aus einer Zeitmessung und einer Temperaturmessung ermitteln, die Spannung geht auf die Bestimmung der Fläche zwischen zwei Stromlinien zurück. Einfache Umrechnungsgleichungen stellen die Verbindung zwischen Modell und Wirklichkeit her.

Electronic Resource

1432-1076

Scanning electron microscopy ; Immature lung ; Bronchiolar epithelium ; Artificial ventilation ; Surfactant replacement

Springer Online Journal Archives 1860-2000

Medicine

Abstract Immature newborn rabbits, delivered on day 27 of gestation were ventilated artificially for 5–10 min with a peak insufflation pressure of about 35 cm H2O, with or without previous treatment with natural surfactant via the airways. The alveolar expansion pattern and the surface structure of the airways were then examined by scanning and transmission electron microscopy. Animals not receiving surfactant had very irregular alveolar expansion and showed prominent desquamation of the bronchiolar epithelium with a strikingly ragged appearance of the mucosa in the scanning electron microscopic images. Litter mates treated with surfactant had improved alveolar expansion and a flattened but otherwise nearly intact bronchiolar epithelium. The findings confirm the beneficial effect of surfactant replacement on the immature neonatal lung.

Electronic Resource

1432-1076

Surfactant ; Hydrophobic apoproteins ; Premature newborn rabbits ; Lung compliance ; Image analysis

Springer Online Journal Archives 1860-2000

Medicine

Abstract Premature rabbit neonates (gestational age 27 days) were treated at birth with natural surfactant purified from chloroform extracts of porcine lung lipids either by acetone precipitation (Surfactant CK, n=10) or liquid gel chromatography (Curosurf, n=22). Another group of animals received artificial surfactant “reconstituted” from isolated low molecular weight (≤15 K) apoproteins and synthetic dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) (Aposurf, n=10). The phospholipid concentrations of the preparations were adjusted to provide the same individual dose of DPPC for each group of treated animals (3 or 4 mg). In comparison with untreated controls from the same litters, there was a 4–7-fold enhancement of lungthorax compliance in all groups of surfactant-treated animals during a 3-h period of artificial ventilation. The average initial (20 min) compliance value was lower in the Aposurf-treated group than in animals receiving natural surfactant preparations, but the difference between the groups gradually diminished and was no longer statistically significant during the 2nd and 3rd h of artificial ventilation. Judged from the fall in tidal volume during ventilation with a short expiration phase (0.17 instead of 0.75s), the apoprotein-based artificial surfactant was also less effective in stabilizing the lungs. A similar conclusion could be drawn from data on alveolar expansion in histological sections, evaluated by automated image analysis. Alveolar volume density was improved only moderately in the Aposurf-treated group (0.24 vs. 0.14; P=0.05), whereas the expected, prominent increase in this parameter was observed in both groups of natural surfactant-treated animals (0.48–0.62 vs. 0.14; P〈0.001). We conclude that a physiologically active artificial surfactant can be prepared from the smaller (≤15 K) apoproteins, DPPC and DPPG; the in vivo effects of this preparation were clearly beneficial, yet inferior to those obtained with the same dose of natural surfactant.

Electronic Resource