Search Results - (Author, Cooperation:G. Churchill)
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1Latest Papers from Table of Contents or Articles in PressMahesh B. Halle, Tesla Yudhistira, Woo-Hyun Lee, Sandip V. Mulay, David G. Churchill
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-05-30Publisher: American Chemical Society (ACS)Print ISSN: 1523-7060Electronic ISSN: 1523-7052Topics: Chemistry and PharmacologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressS. McClatchy ; D. McGann ; R. Gotwals ; A. Baskett ; G. Churchill
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-06-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Biomedical Research/*education ; Chromosome Mapping ; Humans ; Quantitative Trait Loci ; *Students ; Systems Biology/*educationPublished by: -
3Latest Papers from Table of Contents or Articles in PressV. Kumar ; K. Kim ; C. Joseph ; S. Kourrich ; S. H. Yoo ; H. C. Huang ; M. H. Vitaterna ; F. P. de Villena ; G. Churchill ; A. Bonci ; J. S. Takahashi
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-12-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Substitution ; Animals ; Central Nervous System Stimulants/administration & dosage ; Cocaine/*administration & dosage ; Cocaine-Related Disorders/*genetics/*psychology ; *Drug-Seeking Behavior ; Methamphetamine/administration & dosage ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Motor Activity/drug effects ; Mutation ; Nerve Tissue Proteins/genetics/*physiology ; Phenylalanine/genetics ; Polymorphism, Single Nucleotide ; Psychomotor Performance/drug effects ; Quantitative Trait Loci ; Serine/geneticsPublished by: -
4Latest Papers from Table of Contents or Articles in PressKeller, M. P., Gatti, D. M., Schueler, K. L., Rabaglia, M. E., Stapleton, D. S., Simecek, P., Vincent, M., Allen, S., Broman, A. T., Bacher, R., Kendziorski, C., Broman, K. W., Yandell, B. S., Churchill, G. A., Attie, A. D.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-05-02Publisher: Genetics Society of America (GSA)Print ISSN: 0016-6731Topics: BiologyPublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1432-2137Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Key words Pest resistance ; Insect resistance ; QTL analysis ; Lycopersicon esculentum ; Sugar esterSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Lycopersicon pennellii LA716, a wild relative of tomato, is resistant to a number of insect pests due to the accumulation of acylsugars exuded from type IV trichomes. These acylsugars are a class of compounds including both acylglucoses and acylsucroses. Intraspecific populations between L. pennellii LA716 and L. pennellii LA1912, the latter an accession that assorts for low-level acylsugar accumulation, were created to study the inheritance of type IV trichome density, acylsugar accumulation levels, percentage of acylsugars that are acylglucoses, and leaf area. The F2 population was subsequently used to determine genomic regions associated with these traits. The relative proportion of acylglucoses and acylsucroses was found to be largely controlled by a single locus near TG549 on chromosome 3. One locus on chromosome 10 showed significant associations with acylsugar levels. In addition, 1 locus on chromosome 4 showed significant associations with leaf area. Ten additional loci showed modest associations with one or more of the traits examined, 5 of which have been previously reported.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Key words Sugar ester ; Quantitative trait loci ; QTL mapping ; Transglucosylase ; TransacylaseSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Acylsugars exuded by type IV glandular trichomes are responsible for insect resistances found in many Lycopersicon pennellii accessions. Acylsugars are complex mixtures composed of polyacylated sugars (glucose or sucrose) esterified to branched and straight-chain 4 : 0 to 12 : 0 fatty acids. The biogeneses of these unusual fatty acid constituents have their origins in branched-chain amino acid pathways. However, the mechanism of fatty acid elongation in these systems and the genetic control of carbon flux from amino acid to fatty acid pathways remain unclear. In this study, we used an intraspecific F2 population derived from the cross between L. pennellii LA716 and L. pennellii LA1912 to examine the genetic basis of acylsugar fatty acid composition. Six QTLs were detected which, combined, explain 23–60% of the variance observed for each of the nine segregating fatty acid constituents. Both correlation data and QTL analysis data indicate that branched medium-chain fatty acids are synthesized through elongation of short-chain precursors in two-carbon increments. The proportion of iso-branched acylsugar fatty acids that have an even-carbon chain length was found to be primarily determined by a single locus that maps to a location 5.5 cM above TG117 on chromosome 8. QTL function in several cases can be inferred from discrete patterns of fatty acid composition; in other cases, control of acylsugar fatty acid composition appears to be complex.Type of Medium: Electronic ResourceURL: