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1Staff View
Publication Date: 2018-04-18Publisher: American Chemical Society (ACS)Topics: Chemistry and PharmacologyPublished by: -
2L. Jostins ; S. Ripke ; R. K. Weersma ; R. H. Duerr ; D. P. McGovern ; K. Y. Hui ; J. C. Lee ; L. P. Schumm ; Y. Sharma ; C. A. Anderson ; J. Essers ; M. Mitrovic ; K. Ning ; I. Cleynen ; E. Theatre ; S. L. Spain ; S. Raychaudhuri ; P. Goyette ; Z. Wei ; C. Abraham ; J. P. Achkar ; T. Ahmad ; L. Amininejad ; A. N. Ananthakrishnan ; V. Andersen ; J. M. Andrews ; L. Baidoo ; T. Balschun ; P. A. Bampton ; A. Bitton ; G. Boucher ; S. Brand ; C. Buning ; A. Cohain ; S. Cichon ; M. D'Amato ; D. De Jong ; K. L. Devaney ; M. Dubinsky ; C. Edwards ; D. Ellinghaus ; L. R. Ferguson ; D. Franchimont ; K. Fransen ; R. Gearry ; M. Georges ; C. Gieger ; J. Glas ; T. Haritunians ; A. Hart ; C. Hawkey ; M. Hedl ; X. Hu ; T. H. Karlsen ; L. Kupcinskas ; S. Kugathasan ; A. Latiano ; D. Laukens ; I. C. Lawrance ; C. W. Lees ; E. Louis ; G. Mahy ; J. Mansfield ; A. R. Morgan ; C. Mowat ; W. Newman ; O. Palmieri ; C. Y. Ponsioen ; U. Potocnik ; N. J. Prescott ; M. Regueiro ; J. I. Rotter ; R. K. Russell ; J. D. Sanderson ; M. Sans ; J. Satsangi ; S. Schreiber ; L. A. Simms ; J. Sventoraityte ; S. R. Targan ; K. D. Taylor ; M. Tremelling ; H. W. Verspaget ; M. De Vos ; C. Wijmenga ; D. C. Wilson ; J. Winkelmann ; R. J. Xavier ; S. Zeissig ; B. Zhang ; C. K. Zhang ; H. Zhao ; M. S. Silverberg ; V. Annese ; H. Hakonarson ; S. R. Brant ; G. Radford-Smith ; C. G. Mathew ; J. D. Rioux ; E. E. Schadt ; M. J. Daly ; A. Franke ; M. Parkes ; S. Vermeire ; J. C. Barrett ; J. H. Cho
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-11-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Colitis, Ulcerative/genetics/immunology/microbiology/physiopathology ; Crohn Disease/genetics/immunology/microbiology/physiopathology ; Genetic Predisposition to Disease/*genetics ; Genome, Human/genetics ; *Genome-Wide Association Study ; Haplotypes/genetics ; *Host-Pathogen Interactions/genetics/immunology ; Humans ; Inflammatory Bowel Diseases/*genetics/immunology/*microbiology/physiopathology ; Mycobacterium/*immunology/pathogenicity ; Mycobacterium Infections/genetics/microbiology ; Mycobacterium tuberculosis/immunology/pathogenicity ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Reproducibility of ResultsPublished by: -
3T. B. Richardson, P. M. Forster, T. Andrews, O. Boucher, G. Faluvegi, D. Fläschner, M. Kasoar, A. Kirkevåg, J.-F. Lamarque, G. Myhre, D. Olivié, B. H. Samset, D. Shawki, D. Shindell, T. Takemura, A. Voulgarakis
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-03-13Publisher: Wiley-BlackwellPrint ISSN: 0094-8276Electronic ISSN: 1944-8007Topics: GeosciencesPhysicsPublished by: -
4Mohanan, V., Nakata, T., Desch, A. N., Levesque, C., Boroughs, A., Guzman, G., Cao, Z., Creasey, E., Yao, J., Boucher, G., Charron, G., Bhan, A. K., Schenone, M., Carr, S. A., Reinecker, H.-C., Daly, M. J., Rioux, J. D., Lassen, K. G., Xavier, R. J.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, Medicine, DiseasesPublished by: -
5Staff View
ISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesNotes: Abstract. Meiofaunal density and the taxonomic composition of nematodes were investigated in three bottom types of the SW lagoon of New Caledonia (SW Pacific). Meiofaunal density was significantly higher in white-sand bottoms than in other biotopes (grey-sand and muddy bottoms). Thirty-three nematode families and 172 genera were identified. Species diversity indices were significantly lower in back-reef white-sand than in seagrass grey-sand and coastal mud. The familial, generic and species diversity were analysed in relation to ecological and biotic parameters by multivariate factorial correspondence analysis and hierarchical clustering. The analysis at familial level was unable to discriminate between stations and biotopes. The analysis at generic level detected three main nematode associations related to microphytobenthic primary productivity, macrophyte biomass and silt content. Taxonomic composition of one white-sand station (Mbéré reef) differed from all others in relation to an increased chlorophyll/pheophytin ratio and a lower silt content. Grey-sand stations were split in two distinct groups. The first combined two of the three white-sand stations and the grey-sand stations, all of which were characterised by a medium silt content and a medium productivity. The second group combined the muddy bottom stations and the siltiest grey-sand stations which were characterised by a high silt content, a lower macroflora biomass and low productivity.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesNotes: Abstract Ammonium affinity of New Caledonia lagoon benthic communities was measured during the course of 33 in situ enrichment experiments, in order to estimate the contribution of benthos to ammonium fluxes. Ammonium chloride was injected into enclosures pushed into the sediment, in order to obtain a concentration of 20–22 μmol l-1 in the enclosed water which approximated the interstitial water content. Ammonium kinetic uptake was then followed for two hours. Grey-sand bottom displayed the highest affinity for ammonium, but white-sand and muddy bottom affinity was of the same order of magnitude. Macrophytes, and microphytes (when macrophytes are absent), account for the bulk of ammonium bottom uptake. As a result, grey-sand bottoms with their dense macrophyte cover represent a sink for water column nitrogen and play a key role in nutrient cycling of the lagoon.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-1793Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Respiration and calcification were investigated in the ectocochleate cephalopod Nautilus macromphalus Sowerby. Specimens were collected off New Caledonia, in October 1991, and kept at the Nouméa Aquarium until December 1991. The respiratory quotient and calcification rate of 5 individuals were measured during 14 short term incubations (63 to 363 min). Oxygen uptake was recorded with a polarographic oxygen sensor. CO2 flux and calcification were calculated from changes in pH and alkalinity (alkalinity-anomaly technique). Several methods were used to compute the respiratory quotient (RQ); a functional regression indicated an RQ of 0.74. CaCO3 exchange rates were linearly related to respiratory quotient, calcification occurring in individuals with a low RQ. CaCO3 uptake from the surrounding water was noncontinuous. From the highest CaCO3 uptake, maximum growth rate was estimated as 7.1 mg shell wt h- (=61 g yr-1).Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1573-5117Keywords: oxygen and nitrogen fluxes ; metabolic regulation ; oyster biomassSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Oxygen consumption and dissolved nitrogen fluxes at the water-sediment interface of an oyster-bed were measured in situ using transparent enclosures inserted on undisturbed sediment. Experiments were performed in summer, under dark and light conditions, with various densities of the oyster Crassostrea gigas (0–150 animals m − 2). The influence of oyster biomass on oxygen and ammonia exchange rates was similar in both lighting conditions. Oxygen consumption increased with increasing biomass, though not at the level of prediction for the highest biomasses, suggesting a depressed respiration rate. Ammonia release never matched the rates predicted by adding sediment efflux to oyster excretion, when biomass exceeded 100 g DW m − 2. The coupling between oxygen consumption and ammonia release (O : N ratio) was thus influenced by oyster biomass. Stabilization of nitrogen release was related to enhanced nitrification in the presence of oyster and/or sediment uptake of ammonia against the molecular gradient. Urea release was erratic but appeared uninfluenced by oyster biomass. Fluxes of oxygen and of each nitrogen compound displayed thus a specific response to modifications of the oyster biomass. Both the organisms and the sediment are involved in regulation processes of metabolic exchange rates at the water-sediment interface.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1438-3888Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract A multispecific closed-circuit sand ecosystem was fuelled by regular addition of soluble amino acids during 28 months (205 g C m−2 year−1). Bacteria and nematode densities undergo a similar evolution, divided into three main periods: the first 6 to 7 months (numerical decrease), from 6 to 7 to 20 months (numerical stability), after 20 months (numberical increase). Copepod densities are stable during the first seven months, then they exhibit an exponential increase until 14 to 15 month and, thereafler, a decrease. The inter-specific changes were followed for copepods and nematodes. One copepod species progressively overwhelms the fifteen others recorded. During 15 months, the nematodes specific diversity remains important. Although the number of rare species decrease progressively, the relative abundancy of the dominant species remains stable. After 15 month, the population changes according to a pattern of species succession.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1058-8388Keywords: Myoblast ; Chick-quail ; Thoracic muscles ; Limb muscles ; Dermis ; Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineNotes: Interspecific grafting experiments between chick and quail embryos were carried out to investigate the differentiation capacities of myoblasts from different development stages. Grafts consisted of 3.5-day-old embryonic quail dermomyotomes isolated from the cranial level, 7- to 10-day-old and 16-day-old embryonic quail pectoralis muscles, 15-day-old postnatal quail pectoralis muscle, and 3- to 10-day-old embyonic quail cardiac and gut muscles. Grafts were implanted into 2-day-old chick embryos in place of the dorsal halves of somites from the prospective wing level. After implantation of dermomyotome fragments, we observed that quail cells participated in trunk and limb musculature. After implantation of 7- to 10-day-old embryonic muscle, quail cells were rarely found in the limb but systematically took part in the formation of trunk muscles. All these capacities were totally lost in 16-day-old embryonic and 15-day-old postnatal muscles. After implantation of nonsomitic derivatives such as embryonic cardiac and gut muscles, implanted cells never participated either in wing or trunk musculature. After dermomyotome, embryonic muscle, and gut implantation, quail cells were capable of invading the dermis and aggregating into feather germs. Our results extend those previously reported and indicate that somitic myogenic derivatives which do not migrate in the normal course of embryogenesis have migratory potentialities and are able to give rise to axial muscles. All these potentialities are lost as myogenesis proceeds in embryos. © 1994 Wiley-Liss, Inc.Additional Material: 7 Ill.Type of Medium: Electronic ResourceURL: