Search Results - (Author, Cooperation:Flescher)

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  1. 1
    Staff View
    Type of Medium:
    article
    Publication Date:
    2006
    Keywords:
    Kontrastive Linguistik ; Relativsatz ; Übersetzung ; Übersetzungswissenschaft ; Englisch ; Französisch
    In:
    Moderna språk, Bd. 100 (2006) H. 2, S. 288-302, 0026-8577
    Language:
    French
    Note:
    Anmerkungen
    FIS Bildung Literaturdatenbank
  2. 2
  3. 3
    Goldberg, M. ; Flescher, E. ; Gold, D. ; Lengy, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0305-0491
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1437-1596
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
  12. 12
    Jaspers, I. ; Flescher, E. ; Chen, L. C.
    Springer
    Published 1997
    Staff View
    ISSN:
    1420-908X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Flescher, E. ; Snyder, Carroll A.
    Springer
    Published 1995
    Staff View
    ISSN:
    1432-0738
    Keywords:
    Key words Non-steroidal anti-inflammatory drugs ; Benzene ; AP-1 ; Benzoquinone ; NAD(P)H:quinone reductase
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract  Benzene toxicity towards lymphocytes is thought to be mediated by metabolites of benzene including benzoquinone (BQ). NAD(P)H:quinone reductase (QR) is known to protect against BQ toxicity. The expression of the QR gene is regulated by the transcription factor AP-1. We had previously found that aspirin-like drugs (ALD) induce AP-1 in human T lymphocytes. It was therefore hypothesized that ALD would protect lymphocytes against BQ toxicity by inducing QR. Molt-4 cells (M4), a human T lymphocyte cell line, were incubated with different concentrations of two ALD, flurbiprofen and sodium diclofenac, and then exposed to BQ. Toxicity was measured by viability (trypan blue exclusion). Both drugs protected the cells against BQ cytotoxicity in a dose-dependent manner, e.g., sodium diclofenac at 15 μM reduced the fraction of BQ-treated dead cells by 70%. ALDs induced QR activity in the M4 cells in the same range of concentrations that protected the cells against BQ toxicity. The protective effect of ALD was significantly reduced by dicoumarol, a QR-specific inhibitor. Since human T cells and T cell lines do not metabolize arachidonic acid, our data suggest that ALD can protect human T lymphocytes against a metabolite of benzene by induction of QR activity.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Gold, D. ; Flescher, E.
    Springer
    Published 2000
    Staff View
    ISSN:
    1432-1955
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Two decaudation methods used by Schistosoma mansoni cercariae for the production of schistosomula by in vitro transformation were comparatively tested. Both low-pressure syringe passage and vortex mixing of the cercariae produced schistosomula of similar percentages of viability, and the levels of worm recovery following subcutaneous injection in mice were also comparable, though low. By all criteria tested, including simplicity and time requirement, the two methods are equally efficient and are well applicable for mass production of schistosomula.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses