Search Results - (Author, Cooperation:F. Nakagawa)

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  1. 1
    Staff View
    Publication Date:
    2015-12-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adolescent ; Adult ; Africa ; Aged ; Anti-HIV Agents/economics/pharmacology/therapeutic use ; Cost-Benefit Analysis ; HIV Infections/diagnosis/*drug therapy/economics/*virology ; Humans ; Middle Aged ; Precision Medicine/economics/*methods ; *Viral Load/drug effects ; Young Adult
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Glucagon ; Griseolic acid ; Phosphodiesterase inhibitor ; Theophylline ; cAMP ; cGMP
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(85)80103-4

    Articles: DFG German National Licenses
  3. 3
    Yamamoto, K. ; Kohda, Y. ; Saitoh, Y. ; Nakagawa, F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)80595-2

    Articles: DFG German National Licenses
  4. 4
    Aoyama, T. ; Kotaki, H. ; Saitoh, Y. ; Nakagawa, F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)83170-9

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)83057-1

    Articles: DFG German National Licenses
  6. 6
    Uchino, K. ; Yamamura, Y. ; Saitoh, Y. ; Nakagawa, F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0378-4347(00)83680-4

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0378-4347(84)80213-3

    Articles: DFG German National Licenses
  8. 8
    Nagashima, H. ; Okudera, H. ; Orz, Y. ; Kabayashi, S. ; Nakagawa, F.
    Springer
    Published 1999
    Staff View
    ISSN:
    1437-2320
    Keywords:
    Key words Aneurysm ⋅ Anomalies ⋅ Basilar artery ⋅ Endovascular therapy ⋅ Embolization ⋅ Interventional neuroradiology
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Basilar trunk saccular aneurysms associated with fenestration are infrequent, especially in the middle or distal portion of the basilar artery. Surgical treatment of the basilar trunk aneurysm is difficult, due to its anatomical environment and the complicated surgical exposure. A 46-year-old woman presenting with Hunt and Kosnik grade II subarachnoid hemorrhage was found to have a ruptured aneurysm arising at the proximal corner of the associated fenestration in the middle portion of the basilar artery. Because of surgical difficulties anticipated in approaching the aneurysm, it was decided to treat it with endovascular embolization utilizing the Guglielmi detachable coil; and complete occlusion of the aneurysm was obtained. The efficacy of endovascular treatment for the basilar trunk aneurysm with associated fenestration is discussed from anatomical and embryological points of view, and relevant literature is reviewed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s101430050020

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    0942-0940
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary This study was undertaken to examine the differences in aneurysm statistics between University hospitals where subacute or chronic patients are primarily treated and University-affiliated hospitals where both acute and chronic cases are also admitted. In each hospital group, the transition of the statistics in the last decade was studied. The purpose of this study was also to see if any conclusion could be drawn regarding the surgical treatment of acute cases. The death rate for all aneurysm cases admitted is 8% at University hospitals, whilst that at affiliated hospitals is roughly 30% during the 1970s. The operative death rate at the University hospitals is 3%, whilst that at affiliated hospitals is 16% which improved at one affiliated hospital to 8% in the 1980–1981 period. Morbidity also improved in the latest series in the affiliated hospital. These improvements are considered to be due to the change of operative and postoperative policies for acute cases to : limited surgical indications for grade IV patients, extensive cisternal clot removal at the time of surgery, and oral administration of Ticlopidine, a new antiplatelet agent.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01728870

    Articles: DFG German National Licenses
  10. 10
    Shigeta, H. ; Kyoshima, K. ; Nakagawa, F. ; Kobayashi, S.
    Springer
    Published 1992
    Staff View
    ISSN:
    0942-0940
    Keywords:
    Aneurysm ; internal carotid artery ; clipping ; intraoperative rupture
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Aneurysms arising from the dorsal wall of the internal carotid artery are rare. The authors surgically treated twenty dorsal internal carotid artery aneurysms. Pre-operative angiographic findings were reviewed and classified into three types. Eleven aneurysms projecting superiorly on the lateral angiogram were found to be adherent to the base of the frontal lobe by the pterional approach. Five aneurysms which had been superimposed with the internal carotid artery on the lateral angiogram were found adhered to the medial surface of the temporal lobe. Four aneurysms not seen on the angiogram had no adhesion. Two aneurysms, which had not been seen on the initial angiograms, were visualized on the angiograms taken during the period of vasospasm. This type of aneurysms can be the source of a subarachnoid haemorrhage of unknown origin and requires repeated examinations. Premature rupture occured intra-operatively in five cases and postoperative bleeding was encountered in two. Clipping technique is discussed from the viewpoint of preventing intra- and postoperative rupture.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01541780

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0942-0940
    Keywords:
    Keywords: Aneurysm; classification; internal carotid artery; clipping; pterional approach.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary  An intraoperative classification of intradural internal carotid artery (ICA) aneurysms not related to the arterial division but based on their operative presentation and clipping techniques is introduced. On the basis of the surgeon's view of the operative field via the pterional approach in 156 operated intradural ICA aneurysms in 143 patients, these aneurysms were classified according to their location in relation to the long axis of the ICA as either proximal, middle or distal in type and also according to their relation to the cross section of the ICA as either lateral, medial, ventral or dorsal in type. Numerically the largest in frequency is the middle type of aneurysm by axial location and the lateral type of aneurysms by cross sectional location. Eighty five percent of the lateral type aneurysms were at the arterial division. The majority of the large to giant aneurysms were of the ventral type and no dorsal type aneurysms were seen. About one third of the ICA aneurysms in this series were located free of the arterial division. All dorsal type aneurysms and most of the medial type aneurysms were not related to the arterial division.  Clipping techniques were classified into perpendicular and parallel clipping, as to the direction of the clip-blades in relation to the carotid axis. The parallel clipping was further classified into forward clipping, in which a clip was applied from the distal side of the ICA, and reversed clipping, in which a clip was applied from the proximal side of the ICA. Most of the aneurysms located at the arterial division required the perpendicular clipping and those free of the arterial division required the parallel clipping. Furthermore, the forward clipping was useful for proximal type aneurysms and the reversed clipping for distal type aneurysms. For the middle type aneurysms clipping was performed bidirectionally.  This classification includes all types of the ICA aneurysms located at any points along its long axis and on its cross section, and is useful for planning safe and exact clipping of the ICA aneurysms.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s007010050196

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-119X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Summary Labeled lectins specific for different sugars were employed to identify different cell types in pituitaries from six human autopsies and seven dogs. To determine the lectins bound by each cell type, fixed-paraffin embedded sections serial to those stained with lectins were immunostained for specific hormones and the serial pairs were examined in a comparison microscope. In human pituitaries corticotrophs stained selectively with lectins having affinity for α-l-fucose and the core region of complex type N-glycosyl-proteins. Some corticotrophs also stained for the presence of terminal β-galactose. Thyrotrophs stained selectively with a periodate oxidation-borohydride reduction-concanavalin A sequence. Some mammotrophs evidenced content of glycoconjugate with terminal β-galactose. Dendritic cells stained selectively for abundant glycogen with the periodate-reduction-concanavalin A sequence and a lectin from Griffonia simplicifolia. Adenohypophyseal cells of dog pituitary differed in showing absence of terminal β-galactose in corticotrophs, presence of terminal β-galactose in thyrotrophs, presence of glycoconjugate with N-glycosidically bound oligosaccharide in thyrotrophs and gonadotrophs and presence of terminal β-galactose with a different lectin affinity in mammotrophs. The main contributions of lectin histochemistry applied to the pituitary include providing an additional histologic method for identification of some cell types, and localizing glycosylated prohormone or other biochemically unrecognized non-hormone glycoconjugates whose function in pituitary cells remains to be explained.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00508654

    Articles: DFG German National Licenses
  13. 13
    Sawa, T. ; Nakagawa, F. ; Yamamoto, K.
    Springer
    Published 1989
    Staff View
    ISSN:
    1741-2765
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract This paper deals with a three-dimensional deformation analysis of workpieces mounted in fixtures, where the workpieces are finite solid cylinders. The analysis is carried out using a three-dimensional theory of elasticity, where clamping forces caused by chucks are regarded as an axi-asymmetrical load. In numerical calculations, the effects of a number of chuck jaws, the diameter of workpieces and the grasping area on the roundness of the workpieces are shown. For verification, a three-dimensional photoelastic experiment is performed. In addition, the deformation of workpieces is measured by an electric comparator and by holography. The analytical results are satisfactorily consistent with the experimental results.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02323865

    Articles: DFG German National Licenses