Search Results - (Author, Cooperation:F. Matsuda)
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1K. Segawa ; S. Kurata ; Y. Yanagihashi ; T. R. Brummelkamp ; F. Matsuda ; S. Nagata
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-06-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine Triphosphatases/genetics/*metabolism ; *Apoptosis ; Caspases/*metabolism ; Cell Line ; Cell Membrane/*enzymology ; Genetic Testing ; Humans ; Membrane Proteins/*metabolism ; Membrane Transport Proteins ; Phosphatidylserines/*metabolism ; Phospholipid Transfer Proteins/genetics/*metabolism ; Protein TransportPublished by: -
2Y. Okada ; D. Wu ; G. Trynka ; T. Raj ; C. Terao ; K. Ikari ; Y. Kochi ; K. Ohmura ; A. Suzuki ; S. Yoshida ; R. R. Graham ; A. Manoharan ; W. Ortmann ; T. Bhangale ; J. C. Denny ; R. J. Carroll ; A. E. Eyler ; J. D. Greenberg ; J. M. Kremer ; D. A. Pappas ; L. Jiang ; J. Yin ; L. Ye ; D. F. Su ; J. Yang ; G. Xie ; E. Keystone ; H. J. Westra ; T. Esko ; A. Metspalu ; X. Zhou ; N. Gupta ; D. Mirel ; E. A. Stahl ; D. Diogo ; J. Cui ; K. Liao ; M. H. Guo ; K. Myouzen ; T. Kawaguchi ; M. J. Coenen ; P. L. van Riel ; M. A. van de Laar ; H. J. Guchelaar ; T. W. Huizinga ; P. Dieude ; X. Mariette ; S. L. Bridges, Jr. ; A. Zhernakova ; R. E. Toes ; P. P. Tak ; C. Miceli-Richard ; S. Y. Bang ; H. S. Lee ; J. Martin ; M. A. Gonzalez-Gay ; L. Rodriguez-Rodriguez ; S. Rantapaa-Dahlqvist ; L. Arlestig ; H. K. Choi ; Y. Kamatani ; P. Galan ; M. Lathrop ; S. Eyre ; J. Bowes ; A. Barton ; N. de Vries ; L. W. Moreland ; L. A. Criswell ; E. W. Karlson ; A. Taniguchi ; R. Yamada ; M. Kubo ; J. S. Liu ; S. C. Bae ; J. Worthington ; L. Padyukov ; L. Klareskog ; P. K. Gregersen ; S. Raychaudhuri ; B. E. Stranger ; P. L. De Jager ; L. Franke ; P. M. Visscher ; M. A. Brown ; H. Yamanaka ; T. Mimori ; A. Takahashi ; H. Xu ; T. W. Behrens ; K. A. Siminovitch ; S. Momohara ; F. Matsuda ; K. Yamamoto ; R. M. Plenge
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-01-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Arthritis, Rheumatoid/*drug therapy/*genetics/metabolism/pathology ; Asian Continental Ancestry Group/genetics ; Case-Control Studies ; Computational Biology ; *Drug Discovery ; Drug Repositioning ; European Continental Ancestry Group/genetics ; Female ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Hematologic Neoplasms/genetics/metabolism ; Humans ; Male ; Mice ; Mice, Knockout ; *Molecular Targeted Therapy ; Polymorphism, Single Nucleotide/geneticsPublished by: -
3Domon, Y., Arakawa, N., Inoue, T., Matsuda, F., Takahashi, M., Yamamura, N., Kai, K., Kitano, Y.
The American Society for Pharmacology and Experimental Therapeutics
Published 2018Staff ViewPublication Date: 2018-05-05Publisher: The American Society for Pharmacology and Experimental TherapeuticsPrint ISSN: 0022-3565Electronic ISSN: 1521-0103Topics: MedicinePublished by: -
4M. Matsuda, F. K. Lin, R. Yu, J.-G. Cheng, W. Wu, J. P. Sun, J. H. Zhang, P. J. Sun, K. Matsubayashi, T. Miyake, T. Kato, J.-Q. Yan, M. B. Stone, Qimiao Si, J. L. Luo, and Y. Uwatoko
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-07-21Publisher: American Physical Society (APS)Electronic ISSN: 2160-3308Topics: PhysicsPublished by: -
5Okano, M. ; Kimura, Y. ; Kino, K. ; Michigami, Y. ; Sakamoto, S. ; Sugata, Y. ; Maeda, M. ; Matsuda, F. ; Kimura, M. ; Ogawa, T. ; Nishizaki, K.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background We have demonstrated that carbohydrates in Cry j 1, the major allergen of Cryptomeria japonica pollen, play a major role in promoting Cry j 1-specific Th2 response. However, little is known as to whether the carbohydrates directly participate in allergic responses.Objective We sought to determine whether Cry j 1-related oligosaccharides function as IgE and/or T cell epitopes. In addition, the regulatory effect of Cry j 1-related oligosaccharide on Cry j 1-specific T cell responses was investigated.Methods Two monovalent oligosaccharides largely found on Cry j 1, Manα1-6(Manα1-3)(Xylβ1-2)Manβ1-4GlcNAcβ1-4(Fucα1-3)GlcNAc (M3FX), and GlcNAcβ1-2Manα1-6(GlcNAcβ1-2Manα1-3)(Xylβ1-2)Manβ1-4GlcNAcβ1-4(Fucα1-3)GlcNAc (GN2M3FX) were prepared. Manα1-2Manα1-6(Manα1-2Manα1-3)Manα1-6(Manα1-2Manα1-2Manα1-3)Manβ1-4GlcNAcβ1-4GlcNAc (M9A) was used as control. Competitive inhibition ELISA for Cry j 1-specific IgE was performed using these oligosaccharides as inhibitors. In addition, T cell lines specific for Cry j 1 or purified protein derivative of Mycobacterium tubecurosis (PPD) were established, and cellular responses against these oligosaccharides were investigated in the presence or absence of the respective antigens.Results Overall, neither M3FX nor GN2M3FX displayed inhibitory effect on the binding between IgE and Cry j 1. In addition, M3FX did not by itself stimulate Cry j 1 or PPD-specific T cells. However, M3FX significantly inhibited Cry j 1-induced proliferation and IL-4 production in Cry j 1-specific T cells. Such an inhibitory effect was not seen in PPD-specific T cell responses.Conclusion These results suggest that Cry j 1-related oligosaccharides are not major epitopes for IgE or T cells. However, these oligosaccharides have a novel potential to inhibit Cry j 1-specific T cell responses selectively.Type of Medium: Electronic ResourceURL: -
6Nakamura, N. ; Azuma, C. ; Akamizu, T. ; Sugawa, H. ; Matsuda, F. ; Mitsuda, N. ; Honjo, T. ; Mori, T. ; Yamaji, K.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Nagaoka, H. ; Ozawa, K. ; Matsuda, F. ; Hayashida, H. ; Matsumura, R. ; Haino, M. ; Shin, E.K. ; Fukita, Y. ; Soeda, E. ; Yokoyama, K. ; Anand, R. ; Eki, T. ; Honjo, T. ; Imai, T.
Amsterdam : ElsevierStaff ViewISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
8Amakawa, R. ; Jing, W. ; Ozawa, K. ; Matsunami, N. ; Hamaguchi, Y. ; Matsuda, F. ; Kawaichi, M. ; Honjo, T.
Amsterdam : ElsevierStaff ViewISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
9Saito, S. ; Tamura, O. ; Kobayashi, Y. ; Matsuda, F. ; Katoh, T. ; Terashima, S.
Amsterdam : ElsevierStaff ViewISSN: 0040-4020Keywords: 3-O-isopropylidenethreose ; 4-O-benzyl-2 ; ABE ring system ; antitumor antibiotic ; asymmetric synthesis ; diastereoselective reduction ; quinocarcinSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Saito, S. ; Tanaka, K. ; Nakatani, K. ; Matsuda, F. ; Katoh, T. ; Terashima, S.
Amsterdam : ElsevierStaff ViewISSN: 0040-4020Keywords: ABC ring system ; O-acetal formation ; antitumor antibiotic ; asymmetric synthesis ; diastereoselective reduction ; intramolecular N ; quinocarcinSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Katoh, T. ; Kirihara, M. ; Yoshino, T. ; Tamura, O. ; Ikeuchi, F. ; Nakatani, K. ; Matsuda, F. ; Yamada, K. ; Gomi, K. ; Terashima, S. ; Ashizawa, T.
Amsterdam : ElsevierStaff ViewISSN: 0040-4020Keywords: antitumor activity ; cytotoxicity ; quinocarcin ; quinocarcin congeners ; structure-activity relationshipsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0040-4020Keywords: Pd catalyzed coupling ; cytotoxicity ; dienediyne ; enol triflate ; neocarzinostatin chromophoreSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: