Search Results - (Author, Cooperation:F. M. Marassi)

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  1. 1
    Staff View
    Publication Date:
    2012-10-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Disulfides/chemistry/metabolism ; Enzyme Activation ; Heterotrimeric GTP-Binding Proteins/metabolism ; Humans ; Interleukin-8/chemistry/metabolism ; Lipid Bilayers/chemistry/*metabolism ; Models, Molecular ; Molecular Conformation ; Nuclear Magnetic Resonance, Biomolecular ; Phospholipids/chemistry/*metabolism ; Receptors, Interleukin-8A/*chemistry/*metabolism ; Signal Transduction
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1573-5001
    Keywords:
    Solid-state NMR ; Magainin ; Membranes ; Oriented samples ; Structure determination
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Chemistry and Pharmacology
    Notes:
    Summary A three-dimensional 1H chemical shift/1H-15N dipolar coupling/15N chemical shift correlation spectrum was obtained on a sample of specifically 15N-labeled magainin peptides oriented in lipid bilayers between glass plates in a flat-coil probe. The spectrum showed complete resolution of the resonances from two labeled amide sites in all three dimensions. The three orientationally dependent frequencies associated with each resonance enabled the orientation of the peptide planes to be determined relative to the direction of the applied magnetic field. These results demonstrate the feasibility of multiple-pulse spectroscopy in a flat-coil probe, the ability to measure three spectral parameters from each site in a single experiment, and the potential for resolving among many labeled sites in oriented membrane proteins.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00197814

    Articles: DFG German National Licenses