Search Results - (Author, Cooperation:F. A. Ran)
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1F. A. Ran ; L. Cong ; W. X. Yan ; D. A. Scott ; J. S. Gootenberg ; A. J. Kriz ; B. Zetsche ; O. Shalem ; X. Wu ; K. S. Makarova ; E. V. Koonin ; P. A. Sharp ; F. Zhang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; CRISPR-Associated Proteins/genetics/*metabolism ; Cholesterol/blood/metabolism ; Gene Targeting ; Genetic Engineering/*methods ; Genome/*genetics ; Liver/metabolism/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Proprotein Convertases/biosynthesis/blood/deficiency/genetics ; Serine Endopeptidases/biosynthesis/blood/deficiency/genetics ; Staphylococcus aureus/*enzymology/genetics ; Substrate SpecificityPublished by: -
2M. Tabebordbar ; K. Zhu ; J. K. Cheng ; W. L. Chew ; J. J. Widrick ; W. X. Yan ; C. Maesner ; E. Y. Wu ; R. Xiao ; F. A. Ran ; L. Cong ; F. Zhang ; L. H. Vandenberghe ; G. M. Church ; A. J. Wagers
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Exons ; Frameshift Mutation ; Genetic Therapy/*methods ; Mice ; Mice, Inbred mdx ; Muscle, Skeletal/metabolism ; Muscular Dystrophy, Duchenne/genetics/*therapy ; Myocardium/metabolism ; RNA, Messenger/genetics ; Satellite Cells, Skeletal Muscle/*metabolism ; Sequence Deletion ; Transduction, Genetic/*methodsPublished by: -
3C. E. Nelson ; C. H. Hakim ; D. G. Ousterout ; P. I. Thakore ; E. A. Moreb ; R. M. Castellanos Rivera ; S. Madhavan ; X. Pan ; F. A. Ran ; W. X. Yan ; A. Asokan ; F. Zhang ; D. Duan ; C. A. Gersbach
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Dystrophin/*genetics ; Exons/*genetics ; Genetic Therapy/*methods ; Male ; Mice ; Mice, Inbred mdx ; Muscle, Skeletal/*metabolism ; Muscular Dystrophy, Duchenne/genetics/*therapy ; Sequence DeletionPublished by: -
4L. Cong ; F. A. Ran ; D. Cox ; S. Lin ; R. Barretto ; N. Habib ; P. D. Hsu ; X. Wu ; W. Jiang ; L. A. Marraffini ; F. Zhang
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-01-05Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; Caspase 9/*chemistry/genetics ; DNA/chemistry/genetics ; *DNA Cleavage ; Genetic Engineering/*methods ; Genetic Loci ; Genome/*genetics ; Humans ; Inverted Repeat Sequences/*genetics ; Mice ; Microarray Analysis/*methods ; Molecular Sequence Data ; Mutagenesis ; RNA/chemistry/genetics ; Recombinational DNA Repair ; Streptococcus pyogenes/enzymology/geneticsPublished by: -
5M. N. Lee ; C. Ye ; A. C. Villani ; T. Raj ; W. Li ; T. M. Eisenhaure ; S. H. Imboywa ; P. I. Chipendo ; F. A. Ran ; K. Slowikowski ; L. D. Ward ; K. Raddassi ; C. McCabe ; M. H. Lee ; I. Y. Frohlich ; D. A. Hafler ; M. Kellis ; S. Raychaudhuri ; F. Zhang ; B. E. Stranger ; C. O. Benoist ; P. L. De Jager ; A. Regev ; N. Hacohen
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Autoimmune Diseases/genetics ; Communicable Diseases/genetics ; Dendritic Cells/drug effects/*immunology ; Escherichia coli ; Female ; *Gene-Environment Interaction ; Genetic Loci ; Genome-Wide Association Study ; HEK293 Cells ; Host-Pathogen Interactions/*genetics ; Humans ; Influenza A virus ; Interferon Regulatory Factor-7/*genetics ; Interferon-beta/pharmacology ; Lipopolysaccharides/immunology ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; STAT Transcription Factors/*genetics ; Transcriptome ; Young AdultPublished by: