Search Results - (Author, Cooperation:E. V. Koonin)

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  1. 1
    J. K. Colbourne ; M. E. Pfrender ; D. Gilbert ; W. K. Thomas ; A. Tucker ; T. H. Oakley ; S. Tokishita ; A. Aerts ; G. J. Arnold ; M. K. Basu ; D. J. Bauer ; C. E. Caceres ; L. Carmel ; C. Casola ; J. H. Choi ; J. C. Detter ; Q. Dong ; S. Dusheyko ; B. D. Eads ; T. Frohlich ; K. A. Geiler-Samerotte ; D. Gerlach ; P. Hatcher ; S. Jogdeo ; J. Krijgsveld ; E. V. Kriventseva ; D. Kultz ; C. Laforsch ; E. Lindquist ; J. Lopez ; J. R. Manak ; J. Muller ; J. Pangilinan ; R. P. Patwardhan ; S. Pitluck ; E. J. Pritham ; A. Rechtsteiner ; M. Rho ; I. B. Rogozin ; O. Sakarya ; A. Salamov ; S. Schaack ; H. Shapiro ; Y. Shiga ; C. Skalitzky ; Z. Smith ; A. Souvorov ; W. Sung ; Z. Tang ; D. Tsuchiya ; H. Tu ; H. Vos ; M. Wang ; Y. I. Wolf ; H. Yamagata ; T. Yamada ; Y. Ye ; J. R. Shaw ; J. Andrews ; T. J. Crease ; H. Tang ; S. M. Lucas ; H. M. Robertson ; P. Bork ; E. V. Koonin ; E. M. Zdobnov ; I. V. Grigoriev ; M. Lynch ; J. L. Boore
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-02-05
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptation, Physiological ; Amino Acid Sequence ; Animals ; Base Sequence ; Chromosome Mapping ; Daphnia/*genetics/physiology ; *Ecosystem ; Environment ; Evolution, Molecular ; Gene Conversion ; Gene Duplication ; Gene Expression ; Gene Expression Profiling ; Gene Expression Regulation ; Genes ; Genes, Duplicate ; *Genome ; Metabolic Networks and Pathways/genetics ; Molecular Sequence Annotation ; Molecular Sequence Data ; Multigene Family ; Phylogeny ; Sequence Analysis, DNA
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-04-02
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Base Sequence ; CRISPR-Associated Proteins/genetics/*metabolism ; Cholesterol/blood/metabolism ; Gene Targeting ; Genetic Engineering/*methods ; Genome/*genetics ; Liver/metabolism/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Proprotein Convertases/biosynthesis/blood/deficiency/genetics ; Serine Endopeptidases/biosynthesis/blood/deficiency/genetics ; Staphylococcus aureus/*enzymology/genetics ; Substrate Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-09-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Electronic ISSN:
    2375-2548
    Topics:
    Natural Sciences in General
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Koonin, E. V., Makarova, K. S.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-10-12
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Microbiology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Jordan, I. K. ; Kondrashov, F. A. ; Adzhubei, I. A. ; Wolf, Y. I. ; Koonin, E. V. ; Kondrashov, A. S. ; Sunyaev, S.

    [s.l.] : Nature Publishing Group
    Published 2006
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Hurst et al. and, earlier, McDonald confirm the pattern of amino-acid gain and loss that we report. However, they attribute this pattern to properties of the mutation-selection equilibrium, arguing that gainer amino acids are more common than losers among weakly deleterious, rare ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Mushegian, A. R. ; Koonin, E. V.
    Springer
    Published 1993
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Cell-to-cell movement is a crucial step in plant virus infection. In many viruses, the movement function is secured by specific virus-encoded proteins. Amino acid sequence comparisons of these proteins revealed a vast superfamily containing a conserved sequence motif that may comprise a hydrophobic interaction domain. This superfamily combines proteins of viruses belonging to all principal groups of positive-strand RNA viruses, as well as single-stranded DNA containing geminiviruses, double-stranded DNA-containing pararetroviruses (caulimoviruses and badnaviruses), and tospoviruses that have negative-strand RNA genomes with two ambisense segments. In several groups of positive-strand RNA viruses, the movement function is provided by the proteins encoded by the so-called triple gene block including two putative small membrane-associated proteins and a putative RNA helicase. A distinct type of movement proteins with very high content of proline is found in tymoviruses. It is concluded that classification of movement proteins based on comparison of their amino acid sequences does not correlate with the type of genome nucleic acid or with grouping of viruses based on phylogenetic analysis of replicative proteins or with the virus host range. Recombination between unrelated or distantly related viruses could have played a major role in the evolution of the movement function. Limited sequence similarities were observed between i) movement proteins of dianthoviruses and the MIP family of cellular integral membrane proteins, and ii) between movement proteins of bromoviruses and cucumoviruses and M1 protein of influenza viruses which is involved in nuclear export of viral ribonucleoproteins. It is hypothesized that all movement proteins of plant viruses may mediate hydrophobic interactions between viral and cellular macromolecules.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1573-6857
    Keywords:
    essential genes ; microbial genomes ; phylogenetic patterns ; short proteins
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract A complete understanding of the biology of an organism necessarily starts with knowledge of its genetic makeup. Proteins encoded in a genome must be identified and characterized, and the presence or absence of specific sets of proteins must be noted in order to determine the possible biochemical pathways or functional systems utilized by that organism. The COG database presents a set of tools suited to these purposes, including the ability to select protein families (COGs) that contain proteins from a specified set of species. The selection is based upon a phylogenetic pattern, which is a shorthand representation of the presence or absence of a particular species in a COG. Here we present the use of phylogenetic patterns as a means to perform targeted searches for undetected protein-coding genes in complete genomes.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1573-0875
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Geosciences
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses