Search Results - (Author, Cooperation:E. T. Zhang)
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1Latest Papers from Table of Contents or Articles in PressS. C. Knight ; L. Xie ; W. Deng ; B. Guglielmi ; L. B. Witkowsky ; L. Bosanac ; E. T. Zhang ; M. El Beheiry ; J. B. Masson ; M. Dahan ; Z. Liu ; J. A. Doudna ; R. Tjian
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: 3T3 Cells ; Animals ; Bacterial Proteins/chemistry/*metabolism ; *CRISPR-Cas Systems ; Chromatin/chemistry/*metabolism/ultrastructure ; Clustered Regularly Interspaced Short Palindromic Repeats ; *DNA Cleavage ; Endonucleases/chemistry/*metabolism ; *Genetic Engineering ; Genome ; Mice ; Single-Cell AnalysisPublished by: -
2Latest Papers from Table of Contents or Articles in PressM. Hondele ; T. Stuwe ; M. Hassler ; F. Halbach ; A. Bowman ; E. T. Zhang ; B. Nijmeijer ; C. Kotthoff ; V. Rybin ; S. Amlacher ; E. Hurt ; A. G. Ladurner
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-05-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Motifs ; Chaetomium/*chemistry ; Conserved Sequence ; Crystallography, X-Ray ; DNA/chemistry/metabolism ; DNA Replication ; Fungal Proteins/*chemistry/*metabolism ; Histones/chemistry/*metabolism ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Molecular Chaperones/*chemistry/*metabolism ; Nucleosomes/chemistry/metabolism ; Protein Binding ; Protein Multimerization ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Substrate SpecificityPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1432-0533Keywords: Brain extracellular fluid ; Cerebrospinal fluid ; Perivascular cells ; Perivascular spaces ; lympharicsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Pathways for drainage of interstitial fluid and cerebrospinal fluid from the rat brain were investigated by the injection of 2–5 μl Indian ink into cerebral white and grey matter and into the subarachnoid space over the vertex of the left frontal lobe. Animals were killed by formalin or glutaraldehyde perfusion 5 min-2 years after injection, and the distribution of ink over the surface of the brain, in 2-mm slices of brain cleared in cedar wood oil, in paraffin sections and by electron microscopy was documented. These investigations showed that carbon particles were distributed diffusely through the interstitial spaces of the white matter whereas they spread selectively along perivascular spaces in the grey matter outlining both arteries and veins and extending to surround capillaries within 1 h. Carbon particles were rapidly ingested by perivascular cells and, to some extent, by meningeal cells surrounding the larger vessels. Very little movement of carbon-labelled perivascular cells and perivascular macrophages was seen after 2 years. Carbon particles entering the subarachnoid space over the vertex of the cerebral hemispheres drained along selected paravascular and subfrontal pathways in the subarachnoid space to the cribriform plate and thence into nasal lymphatics and cervical lymph nodes. These studies demonstrate the diffuse spread of fluidborne tracers through cerebral white matter in the rat, the perivascular spread of tracer in grey matter and the compartmentalised directional flow or tracer through the subarachnoid space to the cribriform plate and nasal lymphatics. Furthermore, particulate matter selectively injected into perivascular spaces in rat grey matter is rapidly and efficiently ingested by perivascular cells.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesCraig, A. D. ; Bushnell, M. C. ; Zhang, E.-T. ; Blomqvist, A.
[s.l.] : Nature Publishing Group
Published 1994Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Because the sensations of pain and temperature are un-equivocally associated with the spinothalamic tract (STT), understanding their neural mechanisms requires the identifica-tion of the thalamic terminations of the nociceptive and thermo-receptive components of the STT. The half of the STT that ...Type of Medium: Electronic ResourceURL: