Search Results - (Author, Cooperation:E. S. Fischer)
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1Latest Papers from Table of Contents or Articles in PressG. M. Lingaraju ; R. D. Bunker ; S. Cavadini ; D. Hess ; U. Hassiepen ; M. Renatus ; E. S. Fischer ; N. H. Thoma
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing ; Catalytic Domain ; Crystallography, X-Ray ; Enzyme Activation ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; *Models, Molecular ; Multiprotein Complexes/*chemistry ; Peptide Hydrolases/*chemistry/metabolism ; Protein Binding ; Protein Structure, Tertiary ; Transcription Factors/metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2016-02-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites/drug effects ; Casein Kinase Ialpha/chemistry/*metabolism ; Catalytic Domain ; Crystallography, X-Ray ; Humans ; Ikaros Transcription Factor/chemistry/metabolism ; Models, Molecular ; Protein Binding/drug effects ; Proteolysis/drug effects ; Structure-Activity Relationship ; Substrate Specificity/drug effects ; Thalidomide/*analogs & derivatives/chemistry/metabolism/pharmacology ; Ubiquitin-Protein Ligases/chemistry/*metabolism ; Ubiquitination/drug effectsPublished by: -
3Latest Papers from Table of Contents or Articles in PressS. Cavadini ; E. S. Fischer ; R. D. Bunker ; A. Potenza ; G. M. Lingaraju ; K. N. Goldie ; W. I. Mohamed ; M. Faty ; G. Petzold ; R. E. Beckwith ; R. B. Tichkule ; U. Hassiepen ; W. Abdulrahman ; R. S. Pantelic ; S. Matsumoto ; K. Sugasawa ; H. Stahlberg ; N. H. Thoma
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-04-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation ; Apoproteins/chemistry/metabolism/ultrastructure ; Binding Sites ; *Biocatalysis ; Carrier Proteins/chemistry/metabolism/ultrastructure ; Cryoelectron Microscopy ; Crystallography, X-Ray ; Cullin Proteins/chemistry/metabolism/ultrastructure ; DNA Damage ; DNA-Binding Proteins/chemistry/metabolism/ultrastructure ; Humans ; Kinetics ; Models, Molecular ; Multiprotein Complexes/chemistry/*metabolism/*ultrastructure ; Peptide Hydrolases/chemistry/*metabolism/*ultrastructure ; Protein Binding ; Ubiquitination ; Ubiquitins/metabolismPublished by: -
4Latest Papers from Table of Contents or Articles in PressE. S. Fischer ; K. Bohm ; J. R. Lydeard ; H. Yang ; M. B. Stadler ; S. Cavadini ; J. Nagel ; F. Serluca ; V. Acker ; G. M. Lingaraju ; R. B. Tichkule ; M. Schebesta ; W. C. Forrester ; M. Schirle ; U. Hassiepen ; J. Ottl ; M. Hild ; R. E. Beckwith ; J. W. Harper ; J. L. Jenkins ; N. H. Thoma
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Crystallography, X-Ray ; DNA-Binding Proteins/agonists/antagonists & inhibitors/chemistry/metabolism ; Homeodomain Proteins/metabolism ; Humans ; Models, Molecular ; Multiprotein Complexes/agonists/antagonists & inhibitors/chemistry/metabolism ; Peptide Hydrolases/*chemistry/metabolism ; Protein Binding ; Structure-Activity Relationship ; Substrate Specificity ; Thalidomide/analogs & derivatives/*chemistry/metabolism ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/antagonists & inhibitors/*chemistry/metabolismPublished by: -
5Latest Papers from Table of Contents or Articles in PressSievers, Q. L., Gasser, J. A., Cowley, G. S., Fischer, E. S., Ebert, B. L.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-09-21Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Myeloid Neoplasia, Lymphoid NeoplasiaPublished by: -
6Articles: DFG German National LicensesFischer, E. S. ; Lohaus, G. ; Heineke, D. ; Heldt, H. W.
Copenhagen : Munksgaard International Publishers
Published 1998Staff ViewISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Accumulation of assimilates in source leaves of magnesium-deficient plants is a well-known feature. We had wished to determine whether metabolite concentrations in sink leaves and roots are affected by magnesium nutrition. Eight-week-old spinach plants were supplied either with a complete nutrient solution (control plants) or with one lacking Mg (deficient plants) for 12 days. Shoot and root fresh weights and dry weights were lower in deficient than in control plants. Mg concentrations in deficient plants were 11% of controls in source leaves, 12% in sink leaves and 26% in roots, respectively. As compared with controls, increases were found in starch and amino acids in source leaves and in sucrose, hexoses, starch and amino acids in sink leaves, whereas they were only slightly enhanced in roots. In phloem sap of magnesium-deficient and control plants no differences in sucrose and amino acid concentrations were found. To prove that sink leaves were the importing organs they were shaded, which did not alter the response to magnesium deficiency as compared with that without shading. Since in the shaded sink leaves the photosynthetic production of metabolites could be excluded, those carbohydrates and amino acids that accumulated in the sink leaves of the deficient plants must have been imported from the source leaves. It is concluded that in magnesium-deficient spinach plants the growth of sink leaves and roots was not limited by carbohydrate or amino acid supply. It is proposed that the accumulation of assimilates in the source leaves of Mg-deficient plants results from a lack of utilization of assimilates in the sink leaves.Type of Medium: Electronic ResourceURL: