Search Results - (Author, Cooperation:E. Rill)

2012-09-29

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Computer Science

Medicine

Natural Sciences in General

Physics

*Absorbable Implants ; Animals ; Anti-Bacterial Agents ; Electric Power Supplies ; *Electronics ; Metals ; Mice ; Mice, Inbred BALB C ; Oxides ; *Semiconductors ; *Silicon ; Transistors, Electronic ; Wireless Technology

0920-9964

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

0165-1781

Schizophrenia ; brain stem reticular formation ; locus ceruleus ; pedunculopontine nucleus

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Medicine

Electronic Resource

1432-1106

Dorsal columns ; Accuracy ; Projected movements

Springer Online Journal Archives 1860-2000

Medicine

Summary Quantitative evaluation was carried out on the ability of cats to execute a sequential act requiring precise timing for its initiation (jump), accurate projection of the forelimb and appropriate visual tracking during motor performance. Comparison of results before and after section of the Dorsal Columns at the first cervical level revealed obvious postoperative inefficiency in the overall performance of the act. The accuracy of extrapersonally projected movements of the forelimbs (reaching towards a moving target) was seriously affected, as was the capacity to visually track a target in space during the jump. Testing which did not require jumping up towards the target, but merely rearing on the hindlimbs, showed no improvement in the performance of lesioned animals when compared to controls. The deficits mentioned also persisted in animals subjected to preoperative overtraining and prolonged postsurgical testing, a procedure which in certain tasks allows the animal to perform normally after surgery. Physiologically, the Dorsal Columns have been shown to be the exclusive path of fibers from muscle spindles and low threshold joint receptors from the forelimbs. The corresponding fibers from the hindlimbs reach higher centers via different pathways. The loss of this information from forelimbs resulting from high cervical Dorsal Column section may then help to explain the deficits described.

Electronic Resource

0002-9106

Life and Medical Sciences ; Cell & Developmental Biology

Wiley InterScience Backfile Collection 1832-2000

Medicine

The entopeduncular nucleus (EN) in the cat, the homologue of the primate internal globus pallidus and main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from a site in the posterior mesencephalon, then transect the brainstem (precollicular-postmamillary) and elicit locomotion and rhythmic movements of the limbs by stimulation of the same site in the same animal. These studies demostrate the existence of a direct projection from the EN to the mesencephalic locomotor region (MLR). However, this is not a particularly large pathway since fewer than 5% of the EN cells appear to project to the MLR.In a parallel series of anatomical experiments, injections of fluorescent dyes into the area of the MLR induced retrograde labeling of cell bodies in the EN and motor cortex. Injections of tritiated amino acids into the motor cortex resulted in labeling in the area anterior to the MLR. We assume that these connections may be involved, in part, in the sequencing and ordering of series of voluntary movements in which locomotion is involved.

6 Ill.

Electronic Resource