Search Results - (Author, Cooperation:E. Radaelli)

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  1. 1
    Staff View
    Publication Date:
    2016-03-25
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Carcinogenesis/genetics/pathology ; Cell Lineage ; Cell Proliferation ; Cell Survival ; Chromosomes, Human, Pair 3/genetics ; Clone Cells/metabolism/pathology ; Female ; Gene Amplification/genetics ; Gene Knockdown Techniques ; Humans ; Melanoma/*genetics/*pathology/therapy ; Mice ; Microphthalmia-Associated Transcription Factor/genetics ; Mitochondria/genetics/metabolism/pathology ; Mitochondrial Proteins/metabolism ; Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism ; Molecular Targeted Therapy ; Oncogenes/*genetics ; RNA, Long Noncoding/*genetics/therapeutic use ; SOXE Transcription Factors/metabolism ; Xenograft Model Antitumor Assays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-02-16
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0267-8179
    Electronic ISSN:
    1099-1417
    Topics:
    Geography
    Geosciences
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
  4. 4
    Staff View
    Publication Date:
    2018-12-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Medicine, Diseases, Molecular Biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Foschi, D. ; Castoldi, L. ; Corsi, F. ; Radaelli, E. ; Trabucchi, E.
    Springer
    Published 1994
    Staff View
    ISSN:
    1420-908X
    Keywords:
    Corticosteroids ; Protamine ; Angiogenesis ; Inflammation ; Vessels
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract We have studied the antiangiogenetic effects of hydrocortisone and protamine given intra-arterially. The cornea of male, Sprague-Dawley rats were cauterized with silver nitrate. The following treatments were given :30 μg hydrocortisone topical (t.p.), b.i.d., 50 mg/kg/day intraperitoneally (i.p.) or intra-arterially (i.a.), 10 mg/ kg/day protamine i.p. or i.a. Saline was administered to the control groups. In separate experiments we also evaluated the anti-inflammatory effects of hydrocortisone, i.p., on the cauterized corneas. Five days after cauterization, the animals were killed, exsanguinated and India ink was injected to show the network of neovessels. The percentage area of the cornea covered by neovessels was measured morphometrically and evaluated statistically. Hydrocortisone t.p. (−84%), i.a. (−60%) and protamine i.a. (−44%) significantly inhibited angiogenesis in the cauterized cornea. Either drugs, i.p., had any antiangiogenetic effects, but hydrocortisone significantly reduced cell infiltration of the corneas. The results suggest that locoregional administration of antiangiogenetic drugs might be clinically useful.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses