Search Results - (Author, Cooperation:E. Radaelli)
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1E. Leucci ; R. Vendramin ; M. Spinazzi ; P. Laurette ; M. Fiers ; J. Wouters ; E. Radaelli ; S. Eyckerman ; C. Leonelli ; K. Vanderheyden ; A. Rogiers ; E. Hermans ; P. Baatsen ; S. Aerts ; F. Amant ; S. Van Aelst ; J. van den Oord ; B. de Strooper ; I. Davidson ; D. L. Lafontaine ; K. Gevaert ; J. Vandesompele ; P. Mestdagh ; J. C. Marine
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Carcinogenesis/genetics/pathology ; Cell Lineage ; Cell Proliferation ; Cell Survival ; Chromosomes, Human, Pair 3/genetics ; Clone Cells/metabolism/pathology ; Female ; Gene Amplification/genetics ; Gene Knockdown Techniques ; Humans ; Melanoma/*genetics/*pathology/therapy ; Mice ; Microphthalmia-Associated Transcription Factor/genetics ; Mitochondria/genetics/metabolism/pathology ; Mitochondrial Proteins/metabolism ; Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism ; Molecular Targeted Therapy ; Oncogenes/*genetics ; RNA, Long Noncoding/*genetics/therapeutic use ; SOXE Transcription Factors/metabolism ; Xenograft Model Antitumor AssaysPublished by: -
2D. Battistel, M. Roman, A. Marchetti, N. M. Kehrwald, M. Radaelli, E. Balliana, G. Toscano, C. Barbante
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-02-16Publisher: Wiley-BlackwellPrint ISSN: 0267-8179Electronic ISSN: 1099-1417Topics: GeographyGeosciencesPublished by: -
3Carafa, V., Nebbioso, A., Cuomo, F., Rotili, D., Cobellis, G., Bontempo, P., Baldi, A., Spugnini, E. P., Citro, G., Chambery, A., Russo, R., Ruvo, M., Ciana, P., Maravigna, L., Shaik, J., Radaelli, E., De Antonellis, P., Tarantino, D., Pirolli, A., Ragno, R., Zollo, M., Stunnenberg, H. G., Mai, A., Altucci, L.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-06-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Steklov, M., Pandolfi, S., Baietti, M. F., Batiuk, A., Carai, P., Najm, P., Zhang, M., Jang, H., Renzi, F., Cai, Y., Abbasi Asbagh, L., Pastor, T., De Troyer, M., Simicek, M., Radaelli, E., Brems, H., Legius, E., Tavernier, J., Gevaert, K., Impens, F., Messiaen, L., Nussinov, R., Heymans, S., Eyckerman, S., Sablina, A. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-12-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Medicine, Diseases, Molecular BiologyPublished by: -
5Staff View
ISSN: 1420-908XKeywords: Corticosteroids ; Protamine ; Angiogenesis ; Inflammation ; VesselsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We have studied the antiangiogenetic effects of hydrocortisone and protamine given intra-arterially. The cornea of male, Sprague-Dawley rats were cauterized with silver nitrate. The following treatments were given :30 μg hydrocortisone topical (t.p.), b.i.d., 50 mg/kg/day intraperitoneally (i.p.) or intra-arterially (i.a.), 10 mg/ kg/day protamine i.p. or i.a. Saline was administered to the control groups. In separate experiments we also evaluated the anti-inflammatory effects of hydrocortisone, i.p., on the cauterized corneas. Five days after cauterization, the animals were killed, exsanguinated and India ink was injected to show the network of neovessels. The percentage area of the cornea covered by neovessels was measured morphometrically and evaluated statistically. Hydrocortisone t.p. (−84%), i.a. (−60%) and protamine i.a. (−44%) significantly inhibited angiogenesis in the cauterized cornea. Either drugs, i.p., had any antiangiogenetic effects, but hydrocortisone significantly reduced cell infiltration of the corneas. The results suggest that locoregional administration of antiangiogenetic drugs might be clinically useful.Type of Medium: Electronic ResourceURL: