Search Results - (Author, Cooperation:E. Miguel)

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  1. 1
    M. Burke ; S. M. Hsiang ; E. Miguel
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Agriculture/economics/statistics & numerical data ; *Climate ; Developed Countries/economics ; Developing Countries/economics ; Efficiency ; Global Warming/*economics ; Income/statistics & numerical data/trends ; *Internationality ; *Models, Economic ; *Nonlinear Dynamics ; *Temperature ; Time Factors
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-01-05
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Disclosure/*standards/*trends ; Humans ; Research/standards/trends ; Social Sciences/*standards/*trends
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2015-06-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Access to Information ; Disclosure ; *Guidelines as Topic ; Peer Review, Research ; Periodicals as Topic/*standards ; *Reproducibility of Results ; Research/*standards
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    S. M. Hsiang ; M. Burke ; E. Miguel
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-09-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Climate ; Climate Change/*statistics & numerical data ; *Conflict (Psychology) ; Crime/*statistics & numerical data ; Humans ; *Literature Based Discovery ; Violence/statistics & numerical data
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Miguel E. Rodriguez R.
    American Physical Society (APS)
    Published 2018
    Staff View
    Publication Date:
    2018-01-13
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1050-2947
    Electronic ISSN:
    1094-1622
    Topics:
    Physics
    Keywords:
    Fundamental concepts
    Published by:
    http://www.aps.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Nature Publishing Group (NPG)
    Electronic ISSN:
    2158-3188
    Topics:
    Medicine
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C., Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J.-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Quinn, J. F., Saykin, A. J., Schneider, L. S., Smith, A. G., Sonnen, J. A., Stern, R. A., Van Deerlin, V. M., Van Eldik, L. J., Harold, D., Russo, G., Rubinsztein, D. C., Bayer, A., Tsolaki, M., Proitsi, P., Fox, N. C., Hampel, H., Owen, M. J., Mead, S., Passmore, P., Morgan, K., Nöthen, M. M., Rossor, M., Lupton, M. K., Hoffmann, P., Kornhuber, J., Lawlor, B., McQuillin, A., Al-Chalabi, A., Bis, J. C., Ruiz, A., Boada, M., Seshadri, S., Beiser, A., Rice, K., van der Lee, S. J., De Jager, P. L., Geschwind, D. H., Riemenschneider, M., Riedel-Heller, S., Rotter, J. I., Ransmayr, G., Hyman, B. T., Cruchaga, C., Alegret, M., Winsvold, B., Palta, P., Farh, K.-H., Cuenca-Leon, E., Furlotte, N., Kurth, T., Ligthart, L., Terwindt, G. M., Freilinger, T., Ran, C., Gordon, S. D., Borck, G., Adams, H. H. H., Lehtimäki, T., Wedenoja, J., Buring, J. E., Schürks, M., Hrafnsdottir, M., Hottenga, J.-J., Penninx, B., Artto, V., Kaunisto, M., Vepsäläinen, S., Martin, N. G., Montgomery, G. W., Kurki, M. I., Hämäläinen, E., Huang, H., Huang, J., Sandor, C., Webber, C., Muller-Myhsok, B., Schreiber, S., Salomaa, V., Loehrer, E., Göbel, H., Macaya, A., Pozo-Rosich, P., Hansen, T., Werge, T., Kaprio, J., Metspalu, A., Kubisch, C., Ferrari, M. D., Belin, A. C., van den Maagdenberg, A. M. J. M., Zwart, J.-A., Boomsma, D., Eriksson, N., Olesen, J., Chasman, D. I., Nyholt, D. R., Avbersek, A., Baum, L., Berkovic, S., Bradfield, J., Buono, R., Catarino, C. B., Cossette, P., De Jonghe, P., Depondt, C., Dlugos, D., Ferraro, T. N., French, J., Hjalgrim, H., Jamnadas-Khoda, J., Kälviäinen, R., Kunz, W. S., Lerche, H., Leu, C., Lindhout, D., Lo, W., Lowenstein, D., McCormack, M., Moller, R. S., Molloy, A., Ng, P.-W., Oliver, K., Privitera, M., Radtke, R., Ruppert, A.-K., Sander, T., Schachter, S., Schankin, C., Scheffer, I., Schoch, S., Sisodiya, S. M., Smith, P., Sperling, M., Striano, P., Surges, R., Thomas, G. N., Visscher, F., Whelan, C. D., Zara, F., Heinzen, E. L., Marson, A., Becker, F., Stroink, H., Zimprich, F., Gasser, T., Gibbs, R., Heutink, P., Martinez, M., Morris, H. R., Sharma, M., Ryten, M., Mok, K. Y., Pulit, S., Bevan, S., Holliday, E., Attia, J., Battey, T., Boncoraglio, G., Thijs, V., Chen, W.-M., Mitchell, B., Rothwell, P., Sharma, P., Sudlow, C., Vicente, A., Markus, H., Kourkoulis, C., Pera, J., Raffeld, M., Silliman, S., Boraska Perica, V., Thornton, L. M., Huckins, L. M., William Rayner, N., Lewis, C. M., Gratacos, M., Rybakowski, F., Keski-Rahkonen, A., Raevuori, A., Hudson, J. I., Reichborn-Kjennerud, T., Monteleone, P., Karwautz, A., Mannik, K., Baker, J. H., OToole, J. K., Trace, S. E., Davis, O. S. P., Helder, S. G., Ehrlich, S., Herpertz-Dahlmann, B., Danner, U. N., van Elburg, A. A., Clementi, M., Forzan, M., Docampo, E., Lissowska, J., Hauser, J., Tortorella, A., Maj, M., Gonidakis, F., Tziouvas, K., Papezova, H., Yilmaz, Z., Wagner, G., Cohen-Woods, S., Herms, S., Julia, A., Rabionet, R., Dick, D. M., Ripatti, S., Andreassen, O. A., Espeseth, T., Lundervold, A. J., Steen, V. M., Pinto, D., Scherer, S. W., Aschauer, H., Schosser, A., Alfredsson, L., Padyukov, L., Halmi, K. A., Mitchell, J., Strober, M., Bergen, A. W., Kaye, W., Szatkiewicz, J. P., Cormand, B., Ramos-Quiroga, J. A., Sanchez-Mora, C., Ribases, M., Casas, M., Hervas, A., Arranz, M. J., Haavik, J., Zayats, T., Johansson, S., Williams, N., Dempfle, A., Rothenberger, A., Kuntsi, J., Oades, R. D., Banaschewski, T., Franke, B., Buitelaar, J. K., Arias Vasquez, A., Doyle, A. E., Reif, A., Lesch, K.-P., Freitag, C., Rivero, O., Palmason, H., Romanos, M., Langley, K., Rietschel, M., Witt, S. H., Dalsgaard, S., Borglum, A. D., Waldman, I., Wilmot, B., Molly, N., Bau, C. H. D., Crosbie, J., Schachar, R., Loo, S. K., McGough, J. J., Grevet, E. H., Medland, S. E., Robinson, E., Weiss, L. A., Bacchelli, E., Bailey, A., Bal, V., Battaglia, A., Betancur, C., Bolton, P., Cantor, R., Celestino-Soper, P., Dawson, G., De Rubeis, S., Duque, F., Green, A., Klauck, S. M., Leboyer, M., Levitt, P., Maestrini, E., Mane, S., De-Luca, D. M.-, Parr, J., Regan, R., Reichenberg, A., Sandin, S., Vorstman, J., Wassink, T., Wijsman, E., Cook, E., Santangelo, S., Delorme, R., Roge, B., Magalhaes, T., Arking, D., Schulze, T. G., Thompson, R. C., Strohmaier, J., Matthews, K., Melle, I., Morris, D., Blackwood, D., McIntosh, A., Bergen, S. E., Schalling, M., Jamain, S., Maaser, A., Fischer, S. B., Reinbold, C. S., Fullerton, J. M., Guzman-Parra, J., Mayoral, F., Schofield, P. R., Cichon, S., Mühleisen, T. W., Degenhardt, F., Schumacher, J., Bauer, M., Mitchell, P. B., Gershon, E. S., Rice, J., Potash, J. B., Zandi, P. P., Craddock, N., Ferrier, I. N., Alda, M., Rouleau, G. A., Turecki, G., Ophoff, R., Pato, C., Anjorin, A., Stahl, E., Leber, M., Czerski, P. M., Cruceanu, C., Jones, I. R., Posthuma, D., Andlauer, T. F. M., Forstner, A. J., Streit, F., Baune, B. T., Air, T., Sinnamon, G., Wray, N. R., Mac; Intyre, D. J., Porteous, D., Homuth, G., Rivera, M., Grove, J., Middeldorp, C. M., Hickie, I., Pergadia, M., Mehta, D., Smit, J. H., Jansen, R., de Geus, E., Dunn, E., Li, Q. S., Nauck, M., Schoevers, R. A., Beekman, A. T., Knowles, J. A., Viktorin, A., Arnold, P., Barr, C. L., Bedoya-Berrio, G., Bienvenu, O. J., Brentani, H., Burton, C., Camarena, B., Cappi, C., Cath, D., Cavallini, M., Cusi, D., Darrow, S., Denys, D., Derks, E. M., Dietrich, A., Fernandez, T., Figee, M., Freimer, N., Gerber, G., Grados, M., Greenberg, E., Hanna, G. L., Hartmann, A., Hirschtritt, M. E., Hoekstra, P. J., Huang, A., Huyser, C., Illmann, C., Jenike, M., Kuperman, S., Leventhal, B., Lochner, C., Lyon, G. J., Macciardi, F., Madruga-Garrido, M., Malaty, I. A., Maras, A., McGrath, L., Miguel, E. C., Mir, P., Nestadt, G., Nicolini, H., Okun, M. S., Pakstis, A., Paschou, P., Piacentini, J., Pittenger, C., Plessen, K., Ramensky, V., Ramos, E. M., Reus, V., Richter, M. A., Riddle, M. A., Robertson, M. M., Roessner, V., Rosario, M., Samuels, J. F., Sandor, P., Stein, D. J., Tsetsos, F., Van Nieuwerburgh, F., Weatherall, S., Wendland, J. R., Wolanczyk, T., Worbe, Y., Zai, G., Goes, F. S., McLaughlin, N., Nestadt, P. S., Grabe, H.-J., Depienne, C., Konkashbaev, A., Lanzagorta, N., Valencia-Duarte, A., Bramon, E., Buccola, N., Cahn, W., Cairns, M., Chong, S. A., Cohen, D., Crespo-Facorro, B., Crowley, J., Davidson, M., De; Lisi, L., Dinan, T., Donohoe, G., Drapeau, E., Duan, J., Haan, L., Hougaard, D., Karachanak-Yankova, S., Khrunin, A., Klovins, J., Kucinskas, V., Lee Chee Keong, J., Limborska, S., Loughland, C., Lönnqvist, J., Maher, B., Mattheisen, M., McDonald, C., Murphy, K. C., Nenadic, I., van Os, J., Pantelis, C., Pato, M., Petryshen, T., Quested, D., Roussos, P., Sanders, A. R., Schall, U., Schwab, S. G., Sim, K., So, H.-C., Stögmann, E., Subramaniam, M., Toncheva, D., Waddington, J., Walters, J., Weiser, M., Cheng, W., Cloninger, R., Curtis, D., Gejman, P. V., Henskens, F., Mattingsdal, M., Oh, S.-Y., Scott, R., Webb, B., Breen, G., Churchhouse, C., Bulik, C. M., Daly, M., Dichgans, M., Faraone, S. V., Guerreiro, R., Holmans, P., Kendler, K. S., Koeleman, B., Mathews, C. A., Price, A., Scharf, J., Sklar, P., Williams, J., Wood, N. W., Cotsapas, C., Palotie, A., Smoller, J. W., Sullivan, P., Rosand, J., Corvin, A., Neale, B. M.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-06-22
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Genetics, Medicine, Diseases, Online Only
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2018-03-09
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0899-8418
    Electronic ISSN:
    1097-0088
    Topics:
    Geosciences
    Physics
    Published by:
    http://www.wiley.com/wiley-blackwell

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2018-10-31
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1755-1307
    Electronic ISSN:
    1755-1315
    Topics:
    Geography
    Geosciences
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    A case of glomus tumour of the trachea is reported. The patient, a 58-year-old man, complained of dyspnoea, cough and occasional haemoptysis for many years and had been misdiagnosed as having chronic bronchitis. The diagnosis of glomus tumour in a tissue sample taken by bronchoscopy was useful in planning adequate surgery. Light and electronmicroscopy of the excised tumour confirmed the preoperative diagnosis. Immunohistochemical examination showed vimentin and actin in the tumour cells, and negativity for high and low molecular weight keratins, desmin, neurofilaments, and factor VIII-related antigen, findings similar to glomus tumours of other sites.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2559.1991.tb00237.x

    Articles: DFG German National Licenses
  11. 11
    Alonso-Amelot, Miguel E. ; Castillo, Uvidelio ; Smith, Barry L. ; Lauren, Denis R.

    [s.l.] : Nature Publishing Group
    Published 1996
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] SIR - Ptaquiloside, a norsesquiterpene1 found in bracken (Pteridium aquilinum), is a potent carcinogen2 that binds covalently to nucleotides, causing the splitting of uncoiled DNA3. Its potential for causing tumours and other ailments in farm animals is well established4. The observation that milk ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/382587a0

    Articles: DFG German National Licenses
  12. 12
    Dublet, B. ; Dixon, E. ; de Miguel, E. ; van der Rest, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Keywords:
    (Bovine periodontal ligament) ; Amino acid sequence ; Structure homology ; Type XII collagen
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(88)81379-6

    Articles: DFG German National Licenses
  13. 13
    de Miguel, E. ; Rull, L.F. ; Gubbins, K.E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-4371
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-4371(91)90150-B

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0005-2760
    Keywords:
    (Rabbit) ; Phospholipid ; Pulmonary surfactant ; Respiratory distress ; lamellar body
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0005-2760(89)90256-7

    Articles: DFG German National Licenses
  15. 15
    Morales, J.J. ; Nuevo, M.J. ; Rull, L.F. ; de Miguel, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9601
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0375-9601(90)90490-F

    Articles: DFG German National Licenses
  16. 16
    Carracedo, M. C. ; Casares, P. ; Miguel, E.
    Springer
    Published 1989
    Staff View
    ISSN:
    1570-7458
    Keywords:
    Sexual isolation ; sexual maturation ; Drosophila melanogaster ; Drosophila simulans
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Description / Table of Contents:
    Résumé Des lignées isofemelles de D. simulans ont été examinées pour déterminer l'âge de la maturité sexuelle des mâles avec des femelles conspécifiques et pour établir la fréquence de l'hybridation avec des femelles de D. melanogaster. Les mâles ont commencé à être sexuellement mûrs le premier jour après l'émergence, mais leur aptitude à la copulation a augmenté lentement pendant le jour suivant. Les estimations, tant de l'âge du début de la maturation sexuelle que de l'âge du passage de mâle immature à mâle sexuellement mûr dépendaient étroitement des génotypes des femelles utilisées dans les expériences. Il n'y avait pas de différences nettes entre les lignées de mâles. Par contre, des différences dans les fréquences d'hybridation avec les femelles de D. melanogaster ont été observées. De ces résultats, on peut conclure que les différences dans la réussite des hybridations des lignées de mâles de D. simulans n'étaient pas dues à la vitesse de maturation sexuelle des mâles.
    Notes:
    Abstract Isofemale lines of D. simulans were examined to determine the age of sexual maturity of males with conspecific females, and for the frequency of hybridization with D. melanogaster females. Males started to mature sexually on the first day after eclosion but their ability to mate slowly increased during the following day. The estimates of both the age sexual maturation started and the switch from immature to mature males were strongly dependent on the female genotypes used in the tests. No clear differences in speed of maturation were apparent between male lines. In contrast, differences in frequency of hybridization with D. melanogaster females did occur. From the above results it is concluded that the differential hybridization success of male D. simulans lines is not related to the speed at which males mature sexually.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00163250

    Articles: DFG German National Licenses
  17. 17
    Paice, M. G. ; Desrochers, M. ; Rho, D. ; Jurasek, L. ; Roy, C. ; Rollin, C. F. ; Miguel, E. De ; Yaguchi, M.

    [s.l.] : Nature Publishing Company
    Published 1984
    Staff View
    ISSN:
    1546-1696
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    [Auszug] Two endo-β-1,4-glucanases, (EGI and EGII), produced by Schizophyllum commune display similar chemical and physical properties. In addition, their amino terminal amino acid sequences are identical except for an initial 16-residue alanine-rich sequence in EGI. We suggest that one explanation for ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nbt0684-535

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1432-069X
    Keywords:
    Cutaneous osteoma ; Collagen ; Ectopic osteogenesis ; Collagen crosslinks
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Biopsies of a cutaneous osteoma and of normal-looking skin from a 1-year-old girl were studied for histological appearance and collagen biochemistry. The mineralized tissue contained a matrix similar to bone: Only type I collagen, with a hydroxylysine content (0.48%) higher than in the skin (0.35%) and dihydroxylysinonorleucine as the major reducible crosslink. As expected, the normal skin adjacent to the lesions contained type I and type III collagen and as major crosslinks hydroxylysinonorleucine and histidinohydroxymerodesmosine. Histological studies showed the presence of woven bone with very little trabeculation. Numerous active osteoblasts were laying down a rapidly calcified non-lamellar matrix. Osteocytes and multinucleated osteoclasts were also noted. The study demonstrates the osseous nature of the lesion and suggests that an abnormal cell differentiation is associated with this form of osteoma.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00412886

    Articles: DFG German National Licenses
  19. 19
    Cabanela, Miguel E. ; Jowsey, Jenifer
    Springer
    Published 1971
    Staff View
    ISSN:
    1432-0827
    Keywords:
    Bone ; Phosphonates ; Osteoporosis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Physics
    Description / Table of Contents:
    Résumé L'effet d'un diphosphonate, EHDP est étudié dans deux systèmes éxpérimentaux chez le rat: une ostéoporose par immobilisation locale et une ostéoporose générale induite par la cortisone. EHDP est susceptible de prévenir la perte osseuse localisée, induite par l'immobilisation chirurgicale de la patte arrière gauche, mais est inefficace à empêcher la perte osseuse par voie générale induite par l'administration de cortisone. L'action majeure de l'EHDP est la production de grandes quantités d'ostéoide: il a peu d'effet sur la résorption osseuse. Le manque de résultats constants dans les deux systèmes suggère que les troubles osseux d'étiologie générale ne peuvent être étudiés par atrophie osseuse locale.
    Abstract:
    Zusammenfassung Die Wirkung eines Diphosphonates (EHDP) wurde mit zwei verschiedenen Versuchsanordnungen an Ratten untersucht: lokale Immobilisationsosteoporose und generalisierte, durch Cortison hervorgerufene Osteoporose. EHDP konnte den lokalen Knochenschwund verhindern, der durch die chirurgische Immobilisierung des linken Hinterbeines entstand; es verhinderte jedoch den generalisierten, durch Cortisonverabreichung hervorgerufenen Knochenschwund nicht. Die hervorstechendste Wirkung von EHDP ist die Bildung von großen Osteoidmengen; es scheint auf die Knochenresorption nur einen kleinen Einfluß zu haben. Der Mangel an gültigen Befunden bei beiden Versuchsanordnungen läßt darauf schiließen, daß aus einer lokalen Knochenatrophie nicht auf eine durch generalisierten Knochenschwund charakterisierte Erkrankung extrapoliert werden kann.
    Notes:
    Abstract The effect of a diphosphonate, EHDP, was studied in two experimental models in the rat: local immobilization osteoporosis and systemic cortisone-induced osteoporosis. EHDP was able to prevent the local bone loss brought about by surgical immobilization of the left hind limb, but was ineffective in preventing the systemic bone loss produced by cortisone administration. The most prevalent action of EHDP is the production of large amounts of osteoid; it seems to have little effect on bone resorption. The lack of consistent findings in both models suggests that systemic bone-losing disorders cannot be extrapolated from local bone atrophy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02010128

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    1432-2137
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    -1 ) on C inputs and outputs of a Typic Argiudoll and on organic C level and density fractions were studied in a field experiment at the end of 15yr under a corn (Zea mays L.)-wheat (Triticum aestivum L.)-soybean [Glycine max (L.) Merr.] rotation. Microbial biomass and the rate of organic C mineralization during laboratory incubations were also determined. Nitrogen fertilization had no significant influence on C emission in the field, soil organic matter level or microbial biomass and activity. The annual C budget was negative under both tillage systems, but no-tillage lost about 0.7 to 1.5 Mg ha-1yr-1 more C than did plow tillage. Carbon in the medium-density fraction (density=1.6-2.0 g mL-1) of the 0- to 20-cm soil layer was 30% higher (P≤0.05) under no-tillage. Light (density〈1.6 g mL-1) and heavy (density〉2.0 g mL-1) organic fractions, total C, and microbial biomass and activity in the 0- to 20-cm layer were not different in no-tilled and plowed soils, despite different patterns of distribution with depth. The rates of organic C mineralization during laboratory incubations were the same for both tillage systems. We propose that, after an accumulation phase, soil under no-tillage loses higher amounts of CO2--C than under plowing. The use of no-tillage would not significantly affect soil organic matter pools of the region in situations with low erosion losses.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/

    Articles: DFG German National Licenses