Search Results - (Author, Cooperation:E. M. Green)
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1A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in miceE. M. Green ; H. Wakimoto ; R. L. Anderson ; M. J. Evanchik ; J. M. Gorham ; B. C. Harrison ; M. Henze ; R. Kawas ; J. D. Oslob ; H. M. Rodriguez ; Y. Song ; W. Wan ; L. A. Leinwand ; J. A. Spudich ; R. S. McDowell ; J. G. Seidman ; C. E. Seidman
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-02-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Staff View
Publication Date: 2016-04-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation/drug effects ; Allosteric Site/drug effects ; Antidepressive Agents/chemistry/metabolism/pharmacology ; Citalopram/chemistry/metabolism/pharmacology ; Crystallography, X-Ray ; Dopamine Plasma Membrane Transport Proteins/chemistry ; Drug Design ; Extracellular Space/metabolism ; Humans ; Immunoglobulin Fab Fragments/immunology ; Intracellular Space/metabolism ; Ions/chemistry/metabolism ; Ligands ; Models, Molecular ; Paroxetine/chemistry/metabolism/pharmacology ; Protein Binding/drug effects ; Protein Conformation/drug effects ; Protein Stability ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/*chemistry/immunology/*metabolism ; Structure-Activity RelationshipPublished by: -
3S. Charpinet ; G. Fontaine ; P. Brassard ; E. M. Green ; V. Van Grootel ; S. K. Randall ; R. Silvotti ; A. S. Baran ; R. H. Ostensen ; S. D. Kawaler ; J. H. Telting
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Phillips, M. M. ; Suntzeff, Nicholas B. ; Maza, José ; González, L. E. ; Roth, Miguel ; Krisciunas, Kevin ; Morrell, Nidia ; Green, E. M. ; Persson, S. E. ; McCarthy, P. J. ; Hamuy, Mario
[s.l.] : Macmillian Magazines Ltd.
Published 2003Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Stars that explode as supernovae come in two main classes. A type Ia supernova is recognized by the absence of hydrogen and the presence of elements such as silicon and sulphur in its spectrum; this class of supernova is thought to produce the majority of iron-peak elements in the Universe. ...Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] By electron microscopy using the carbon replica technique3 we have obtained direct evidence for a structure repeating at 46 A. along the axis of the virus. A longitudinal structure of ridges and furrows has also been resolved which may indicate a polygonal cross-section for the virus rod. This is ...Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Abstract Solvent-producing cultures of Clostridium beijerinckii NCIMB 8052 can reduce a variety of aldehydes and ketones to the corresponding alcohols, but the enzymes that catalyse these biotransformations have not been identified. The possibility that butanol dehydrogenases were involved was tested by comparing the ability of solvent- and acid-producing pH-auxostat cultures to reduce representative biotransformation substrates. The ability of the cultures to produce solvents was manipulated by controlling the biomass concentration, and this was achieved by varying the glucose concentration in the inflowing medium. The solvent-producing culture could reduce cyclohexanone and benzaldehyde. In contrast, very little reduction of these substrates occurred in the acid-producing culture. This suggested that one or more butanol dehydrogenases did indeed catalyse these biotransformations.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Abstract Solvent-producing cultures of Clostridium beijerinckii NCIMB 8052 can reduce a variety of aldehydes and ketones to the corresponding alcohols, but the enzymes that catalyse these biotransformations have not been identified. The possibility that butanol dehydrogenases were involved was tested by comparing the ability of solvent- and acid-producing pH-auxostat cultures to reduce representative biotransformation substrates. The ability of the cultures to produce solvents was manipulated by controlling the biomass concentration, and this was achieved by varying the glucose concentration in the inflowing medium. The solvent-producing culture could reduce cyclohexanone and benzaldehyde. In contrast, very little reduction of these substrates occured in the acid-producing culture. This suggested that one or more butanol dehydrogenases did indeed catalyse these biotransformations.Type of Medium: Electronic ResourceURL: