Search Results - (Author, Cooperation:E. Jeffrey)

2014-04-25

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

2014-11-14

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

2015-03-06

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

1468-2257

Blackwell Publishing Journal Backfiles 1879-2005

Geography

Economics

Among the most destructive legacies of apartheid in South Africa is the violent history of division, discrimination, and control through which the everyday injustices of racial order were experienced. This violence of ‘separate development’ was inscribed within particular spaces, as the apartheid state attempted to define and control where racially-defined citizens could live, work, and travel. This paper examines the geography of violence and reconstruction in one such space, that of Cato Manor near Durban. The area is known for the large-scale forced removals which took place there in the 1950s, destroying a multi-racial community of Indian and African residents. Although zoned for white residence, Cato Manor remained vacant until the 1980s, when it became a safe haven for refugees fleeing violence in the Natal countryside. In the early 1990s, the area became the focus of a non-racial development effort, which sought to overcome the violent social divisions of the apartheid era. This redevelopment, however, became a site of contestation when former residents of Cato Manor petitioned to reclaim land they once owned there, claims that the city of Durban attempted to nullify in court. The outcome of the land claims trial highlights the tensions between the present dictates of development and the process of negotiating the violence of the past, and suggests that the democratization of planning can be a means of ‘working through’ the legacies of displacement and dispossession that are so much a part of South Africa's present.

Electronic Resource

1744-6570

Blackwell Publishing Journal Backfiles 1879-2005

Psychology

Millions of employees now use portable electronic tools to do their jobs from a “virtual office” with extensive flexibility in the timing and location of work. However, little scholarly research exists about the effects of this burgeoning work form. This study of IBM employees explored influences of the virtual office on aspects of work and work/life balance as reported by virtual office teleworkers (n = 157) and an equivalent group of traditional office workers (n= 89). Qualitative analyses revealed the perception of greater productivity, higher morale, increased flexibility and longer work hours due to telework, as well as an equivocal influence on work/life balance and a negative influence on teamwork. Using a quasi-experimental design, quantitative multivariate analyses supported the qualitative findings related to productivity, flexibility and work/life balance. However, multivariate analyses failed to support the qualitative findings for morale, teamwork and work hours. This study highlights the need for a multi-method approach, including both qualitative and quantitative elements, when studying telework.

Electronic Resource

1600-0838

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Sports Science

Purpose: The purpose of this study was to determine the effects of 6 months of whole-body resistive training (RT) on total and regional bone mineral density (BMD) and bone mineral content (BMC) by age and gender in young and older men and women.Methods: Younger men (n=10) and women (n=7) aged 20–29 years (25±1 years) and older men (n=10) and women (n=10) aged 65–74 years (69±1 years) participated in 6 months of progressive whole-body RT. Upper- and lower-body strength was assessed by the one repetition maximum (1RM) test, and total body fat, lean tissue mass, femoral neck BMD, Ward's triangle BMD, greater trochanter BMD, total-body BMD, and L2–L4 spine BMD were determined by dual-energy X-ray absorptiometry before and after 6 months of RT.Results: Percent body fat decreased only in the young men (P〈0.05). Lean tissue mass increased after training in young men and women and older men (P〈0.05) but did not change significantly in older women. Upper- and lower-body 1RM strength increased in all groups (P〈0.01). Overall, there was a significant increase in BMD at the femoral neck, ward's triangle and greater trochanter BMD, as well as total body BMC and leg BMC (P〈0.05). Total-body BMD and L2–L4 spine BMD did not change with RT. There were no gender differences in the training response between men and women for any of the BMD regions and no age differences in the training response, except for a trend between young and older subjects for femoral neck (P〈0.08).Conclusion: A 6-month RT program increases muscle mass and improves BMD of the femoral region in young and healthy older men and women as a group, with a trend for this to be greater in young subjects.

Electronic Resource

1749-6632

Blackwell Publishing Journal Backfiles 1879-2005

Natural Sciences in General

Electronic Resource

0192-513X

Sociology

Fatherhood

1534-4681

Melanoma ; Lymphoscintigraphy ; Sentinel lymph node

Springer Online Journal Archives 1860-2000

Medicine

Abstract Background: Although previous studies have demonstrated that truncal site is associated with an adverse prognosis, explanations for such risk are lacking. In addition, the number of nodal basins as well as the number of lymph nodes containing regional metastases are important prognostic factors in these patients. Because the lymphatic drainage pattern of truncal melanoma often includes more than one basin, we designed a study to evaluate (1) whether patients with multiple nodal basin drainage (MNBD) were at an increased risk of lymph node metastases identified by sentinel lymph node (SLN) biopsy, and (2) whether the histological status of an individual basin reliably predicted the status of the other draining basins in patients with MNBD. Methods: The records of 295 consecutive truncal melanoma patients who were managed primarily with intraoperative lymphatic mapping and SLN biopsy, between 1991 and 1997, were reviewed. All patients underwent preoperative lymphoscintigraphy, which established the number and location of draining nodal basins. Univariate and multivariate analyses of relevant clinicopathological factors were performed to assess which factors may predict the presence of a pathologically positive SLN. Results: At least one SLN was identified in 281 patients. MNBD was present in 86 (31%) patients, and a pathologically positive SLN was found in 56 (20%) patients. By multivariate analysis, the presence of MNBD (relative risk = 1.9; P = .03), tumor thickness (P = .007), and tumor ulceration (relative risk = 2.4; P = .01) were significant independent risk factors for the presence of at least one pathologically positive SLN. SLN pathology in one basin did not predict the histology of other basins in 19 (22%) of 86 patients with MNBD. Conclusions: MNBD is independently associated with an increased risk of nodal metastases in truncal melanoma patients. Because the histological status of an individual basin did not reliably predict the status of the other draining basins in patients with MNBD, it is important to adequately identify and completely assess all nodal basins at risk, as defined by lymphoscintigraphy, in truncal melanoma patients.

Electronic Resource

1534-4681

Lymphatic mapping ; Prognostic factors ; Sentinel lymph node biopsy.

Springer Online Journal Archives 1860-2000

Medicine

Abstract Background: Historically, patients with thick (≥4 mm) primary melanoma have not been considered candidates for elective lymph node dissection, because their risk for occult distant disease is significant. Sentinel lymph node (SLN) biopsy offers an alternative approach to assess disease in the regional nodal basin, but no studies have specifically addressed the role for this technique in patients with thick melanoma. Although adjuvant therapy benefits patients who develop nodal metastases, data that supports its routine use in all patients with thick melanoma is both limited and controversial. This study was performed to determine whether pathological status of the SLN is an important risk factor in this heterogeneous group and, thus, provides a rationale for SLN biopsy. Methods: The records of 131 patients with primary cutaneous melanoma whose primary tumors were at least 4 mm thick and who underwent lymphatic mapping and SLN biopsy were reviewed. Several known prognostic factors, i.e., tumor thickness, ulceration, Clark level, location, sex, as well as SLN pathological status were analyzed with respect to disease-free and overall survival. Results: Lymphatic mapping and SLN biopsy was successful in 126 (96%) of 131 patients who underwent the procedure. In 49 patients (39%), the SLN biopsy was positive by conventional histology, although it was negative in 77 patients (61%). The median follow-up was 3 years. Although presence of ulceration and SLN status were independent prognostic factors with respect to disease-free and overall survival, SLN status was the most powerful predictor of overall survival by univariate and multivariate analyses. Conclusions: Lymphatic mapping and SLN biopsy is a highly accurate method of staging lymph node basins at risk for regional metastases in patients with thick melanoma and identifies those patients who may benefit from earlier lymphadenectomy as well as patients with a more favorable prognosis. Pathological status of the SLN in these patients with clinically negative nodes is the most important prognostic factor for survival and is essential to establish stratification criteria for future adjuvant trials in this high-risk group.

Electronic Resource

1534-4681

Melanoma ; Surgery ; Margins ; Recurrence ; Treatment

Springer Online Journal Archives 1860-2000

Medicine

Abstract Background: Randomized trials have demonstrated the efficacy of 1- and 2-cm excision margins for thin and intermediate-thickness melanomas, respectively. The optimal margin of excision for thick melanomas is still unknown, however. We evaluated whether the margins used for intermediate-thickness melanomas can be applied safely to thicker lesions. Methods: The charts of 278 patients with thick primary melanomas treated between 1985 and 1996 were retrospectively reviewed. Patients with distant metastases at presentation or with follow-up less than 6 months were excluded. Median follow-up was 27 months. Known melanoma prognostic factors and excision margins were evaluated for their impact on local recurrence (LR), disease-free survival (DFS), and overall survival (OS). Results: Median tumor thickness was 6.0 mm, and 57% were ulcerated. At presentation, 201 patients (72%) were node negative and 77 (28%) were node positive (palpable or occult). The 5-year OS and DFS rates were 55% and 30%, respectively. The LR rate for all patients was 12%. Although nodal status, thickness, and ulceration were significantly associated with OS by multivariate analysis, neither LR nor excisional margin (〈2 cm vs. 〉2 cm) significantly affected DFS or OS in these patients. Conclusions: Because margins of excision greater than 2 cm do not improve LR, DFS, or OS compared to a margin of 2 cm or less, a 2-cm margin of excision is adequate for patients with thick melanoma. Because nodal status is a significant prognostic factor in these patients, staging by sentinel node biopsy should be considered in patients with thick melanomas and clinically negative nodal basins to allow proper entry and stratification in adjuvant therapy trials.

Electronic Resource

article

2010

Didaktik ; Lehrmaterial ; Institutionalismus ; Analyse ; Publikation ; Strategisches Management

Academy of Management learning & education, Bd. 9 (2010) H. 4, S. 663-681, 1537-260X

1944-9585

English

article

2011

Bildungsforschung ; Pädagogische Forschung ; Schuljahr 02 ; Schuljahr 05 ; Lernen ; Unterrichtseinheit ; Fläche ; Rauminhalt ; Umfang ; Musikgruppe ; Lautstärke ; Messverfahren ; Volumen ; Bewertung

ZDM : mathematics education, Bd. 43 (2011) H. 5, S. 637-650, 1863-9690

1863-9704

English

book

2014

Entscheidung ; Wohnen ; Gesundheitspolitik ; Medizin ; Gerechtigkeit ; Allokation ; Standortwahl ; Praktikum ; Arbeitspapier ; Simulation ; Absolvent ; Spanien

English

article

1981

Gewalt ; Sport ; Jugendlicher ; USA

Youth & society, Bd. 13 (1981) H. 2, S. 229-244, 0044-118X

English

Literaturangaben 11

article

2013

Bildungsgeschichte ; Bildungsreform ; Public School ; Schulprogramm ; Interkulturelle Bildung ; Interkulturelles Lernen ; Geschichte (Histor) ; Gleichheit ; Soziale Gerechtigkeit ; 20. Jahrhundert ; Nachkriegszeit ; Vielfalt ; Detroit, Mich. ; USA

Paedagogica historica, Bd. 49 (2013) H. 3, S. [361]-381, 0030-9230

1477-674X

English

Literaturangaben

article

2014

Kompetenz ; Psychische Störung ; Arbeitsmarktchance ; Arbeitsplatz ; Berufliche Integration ; Beschäftigungsförderung ; Behinderung ; Verhaltensauffälliger ; Alter ; Änderung ; Werkstatt für behinderte Menschen ; Geistig behinderter Mensch ; USA

Journal of vocational rehabilitation, Bd. 41 (2014) H. 3, S. 165-178, 1052-2263

1878-6316

English

2018-01-24

Wiley-Blackwell

0007-1048

1365-2141

Medicine

2018-05-19

The American Society for Biochemistry and Molecular Biology (ASBMB)

0021-9258

1083-351X

Biology

Chemistry and Pharmacology

2018-06-19

American Heart Association (AHA)

1524-4539

Medicine

Basic Science Research, Hemodynamics, Physiology