Search Results - (Author, Cooperation:E. Hermans)
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1Latest Papers from Table of Contents or Articles in PressE. Leucci ; R. Vendramin ; M. Spinazzi ; P. Laurette ; M. Fiers ; J. Wouters ; E. Radaelli ; S. Eyckerman ; C. Leonelli ; K. Vanderheyden ; A. Rogiers ; E. Hermans ; P. Baatsen ; S. Aerts ; F. Amant ; S. Van Aelst ; J. van den Oord ; B. de Strooper ; I. Davidson ; D. L. Lafontaine ; K. Gevaert ; J. Vandesompele ; P. Mestdagh ; J. C. Marine
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Carcinogenesis/genetics/pathology ; Cell Lineage ; Cell Proliferation ; Cell Survival ; Chromosomes, Human, Pair 3/genetics ; Clone Cells/metabolism/pathology ; Female ; Gene Amplification/genetics ; Gene Knockdown Techniques ; Humans ; Melanoma/*genetics/*pathology/therapy ; Mice ; Microphthalmia-Associated Transcription Factor/genetics ; Mitochondria/genetics/metabolism/pathology ; Mitochondrial Proteins/metabolism ; Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism ; Molecular Targeted Therapy ; Oncogenes/*genetics ; RNA, Long Noncoding/*genetics/therapeutic use ; SOXE Transcription Factors/metabolism ; Xenograft Model Antitumor AssaysPublished by: -
2Articles: DFG German National LicensesHermans, E. ; Young, K. W. ; Challiss, R. A. J. ; Nahorski, S. R.
Oxford, UK : Blackwell Science Ltd
Published 1998Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Stable expression of the human type 1α metabotropic glutamate (mGlu1α) receptor was achieved in Chinese hamster ovary cells using an isopropyl-β-d-thiogalactoside (IPTG)-repressible expression system. Treatment of the cells with IPTG resulted in a time- and concentration-dependent induction of receptor expression. Maximal expression was obtained after treatment of the cells with 100 µM IPTG for 20 h, leading to a marked increase in receptor immunoreactivity detected by western blot, 〉30-fold stimulation of 3H-labelled inositol phosphate (3H-InsP) production, and a robust increase in intracellular calcium concentration in single cells after stimulation with 20 µM quisqualate. The basal level of 3H-InsP accumulation in cells induced with IPTG was increased by two- to threefold as compared with control cells; however, this basal activity was found to be dependent on glutamate released by the cells into the incubation medium. Following IPTG treatment, stable expression of the mGlu1α receptor was maintained for at least 1 week. Taken together, these results clearly indicate the advantages of working with an inducible expression system when studying the biochemical and pharmacological properties of the human mGlu1α receptor in transfected cells.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Keywords: Calcium homeostasis ; Duchenne muscular dystrophy ; ParvalbuminSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesDe Schryver, F.C. ; Declercq, D. ; Depaemelaere, S. ; Hermans, E. ; Onkelinx, A. ; Verhoeven, J.W. ; Gelan, J.
Amsterdam : ElsevierStaff ViewISSN: 1010-6030Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesLohle, P. N. M. ; Puylaert, J. B. C. M. ; Coerkamp, E. G. ; Hermans, E. T. H.
Springer
Published 1995Staff ViewISSN: 1432-0509Keywords: Appendicitis ; Computed tomography ; Hemorrhage ; Muscles, abdominal wall ; UltrasonographySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Within a period of 5 years, we encountered three patients with a small rectus sheath hematoma, presenting with clinical signs of appendicitis. The rectus sheath hematoma was diagnosed by ultrasound (US) in all three cases and confirmed by computed tomography (CT) in two. None of the hematomas was palpable and in two of three cases in which the patient did not receive anticoagulant therapy. In patients who are sonographically examined for suspected appendicitis, the abdominal wall should be studied as well, to exclude a non-palpable rectus sheath hematoma. In cases in which a hematoma is found, an unnecessary appendectomy can be prevented.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1573-5036Keywords: Hayfields ; Numerical analysis ; Nutrient availability ; Phosphate ; VegetationSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Summary In vegetation research selection of a technique for the analysis of phosphate in soil frequently presents problems with respect to selection criteria. In plant communities of hayfields in Drenthe (The Netherlands) such a criterium has been found by means of drawing axes with different ordination techniques (9 techniques, 43 axes). Each numerical approach obtained one or two axes, which were evidently related to variation in phosphate. Five different extraction techniques were used (Ammonium lactate, EDTA, KF, NaHCO3 and water). The outcome of these analyses could be classified in two groups: 1. P-KF and P-W (correlated with the ground water level) and 2. P-AL, P-EDTA and P-NaHCO3 (correlated with pH). The first group showed clearer relations with the relevant ordination axes. Phosphate indicator values according to Kruijne (P-citric acid) were related to the first group only. P-KF had higher correlations with the ordination axes.Type of Medium: Electronic ResourceURL: