Search Results - (Author, Cooperation:E. Fleischmann)
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1M. W. Carroll ; D. A. Matthews ; J. A. Hiscox ; M. J. Elmore ; G. Pollakis ; A. Rambaut ; R. Hewson ; I. Garcia-Dorival ; J. A. Bore ; R. Koundouno ; S. Abdellati ; B. Afrough ; J. Aiyepada ; P. Akhilomen ; D. Asogun ; B. Atkinson ; M. Badusche ; A. Bah ; S. Bate ; J. Baumann ; D. Becker ; B. Becker-Ziaja ; A. Bocquin ; B. Borremans ; A. Bosworth ; J. P. Boettcher ; A. Cannas ; F. Carletti ; C. Castilletti ; S. Clark ; F. Colavita ; S. Diederich ; A. Donatus ; S. Duraffour ; D. Ehichioya ; H. Ellerbrok ; M. D. Fernandez-Garcia ; A. Fizet ; E. Fleischmann ; S. Gryseels ; A. Hermelink ; J. Hinzmann ; U. Hopf-Guevara ; Y. Ighodalo ; L. Jameson ; A. Kelterbaum ; Z. Kis ; S. Kloth ; C. Kohl ; M. Korva ; A. Kraus ; E. Kuisma ; A. Kurth ; B. Liedigk ; C. H. Logue ; A. Ludtke ; P. Maes ; J. McCowen ; S. Mely ; M. Mertens ; S. Meschi ; B. Meyer ; J. Michel ; P. Molkenthin ; C. Munoz-Fontela ; D. Muth ; E. N. Newman ; D. Ngabo ; L. Oestereich ; J. Okosun ; T. Olokor ; R. Omiunu ; E. Omomoh ; E. Pallasch ; B. Palyi ; J. Portmann ; T. Pottage ; C. Pratt ; S. Priesnitz ; S. Quartu ; J. Rappe ; J. Repits ; M. Richter ; M. Rudolf ; A. Sachse ; K. M. Schmidt ; G. Schudt ; T. Strecker ; R. Thom ; S. Thomas ; E. Tobin ; H. Tolley ; J. Trautner ; T. Vermoesen ; I. Vitoriano ; M. Wagner ; S. Wolff ; C. Yue ; M. R. Capobianchi ; B. Kretschmer ; Y. Hall ; J. G. Kenny ; N. Y. Rickett ; G. Dudas ; C. E. Coltart ; R. Kerber ; D. Steer ; C. Wright ; F. Senyah ; S. Keita ; P. Drury ; B. Diallo ; H. de Clerck ; M. Van Herp ; A. Sprecher ; A. Traore ; M. Diakite ; M. K. Konde ; L. Koivogui ; N. Magassouba ; T. Avsic-Zupanc ; A. Nitsche ; M. Strasser ; G. Ippolito ; S. Becker ; K. Stoecker ; M. Gabriel ; H. Raoul ; A. Di Caro ; R. Wolfel ; P. Formenty ; S. Gunther
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2P. Ruibal ; L. Oestereich ; A. Ludtke ; B. Becker-Ziaja ; D. M. Wozniak ; R. Kerber ; M. Korva ; M. Cabeza-Cabrerizo ; J. A. Bore ; F. R. Koundouno ; S. Duraffour ; R. Weller ; A. Thorenz ; E. Cimini ; D. Viola ; C. Agrati ; J. Repits ; B. Afrough ; L. A. Cowley ; D. Ngabo ; J. Hinzmann ; M. Mertens ; I. Vitoriano ; C. H. Logue ; J. P. Boettcher ; E. Pallasch ; A. Sachse ; A. Bah ; K. Nitzsche ; E. Kuisma ; J. Michel ; T. Holm ; E. G. Zekeng ; I. Garcia-Dorival ; R. Wolfel ; K. Stoecker ; E. Fleischmann ; T. Strecker ; A. Di Caro ; T. Avsic-Zupanc ; A. Kurth ; S. Meschi ; S. Mely ; E. Newman ; A. Bocquin ; Z. Kis ; A. Kelterbaum ; P. Molkenthin ; F. Carletti ; J. Portmann ; S. Wolff ; C. Castilletti ; G. Schudt ; A. Fizet ; L. J. Ottowell ; E. Herker ; T. Jacobs ; B. Kretschmer ; E. Severi ; N. Ouedraogo ; M. Lago ; A. Negredo ; L. Franco ; P. Anda ; S. Schmiedel ; B. Kreuels ; D. Wichmann ; M. M. Addo ; A. W. Lohse ; H. De Clerck ; C. Nanclares ; S. Jonckheere ; M. Van Herp ; A. Sprecher ; G. Xiaojiang ; M. Carrington ; O. Miranda ; C. M. Castro ; M. Gabriel ; P. Drury ; P. Formenty ; B. Diallo ; L. Koivogui ; N. Magassouba ; M. W. Carroll ; S. Gunther ; C. Munoz-Fontela
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-05-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: CTLA-4 Antigen/metabolism ; Ebolavirus/*immunology ; Female ; Flow Cytometry ; Guinea/epidemiology ; Hemorrhagic Fever, Ebola/*immunology/mortality/*physiopathology ; Humans ; Inflammation Mediators/immunology ; Longitudinal Studies ; Lymphocyte Activation ; Male ; Patient Discharge ; Programmed Cell Death 1 Receptor/metabolism ; Survivors ; T-Lymphocytes/*immunology/metabolism ; Viral LoadPublished by: -
3Carr, E., Fleischmann, M., Goldberg, M., Kuh, D., Murray, E. T., Stafford, M., Stansfeld, S., Vahtera, J., Xue, B., Zaninotto, P., Zins, M., Head, J.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-04-13Publisher: BMJ Publishing GroupPrint ISSN: 1351-0711Electronic ISSN: 1470-7926Topics: MedicineKeywords: Open accessPublished by: -
4J. Quick ; N. J. Loman ; S. Duraffour ; J. T. Simpson ; E. Severi ; L. Cowley ; J. A. Bore ; R. Koundouno ; G. Dudas ; A. Mikhail ; N. Ouedraogo ; B. Afrough ; A. Bah ; J. H. Baum ; B. Becker-Ziaja ; J. P. Boettcher ; M. Cabeza-Cabrerizo ; A. Camino-Sanchez ; L. L. Carter ; J. Doerrbecker ; T. Enkirch ; I. Garcia-Dorival ; N. Hetzelt ; J. Hinzmann ; T. Holm ; L. E. Kafetzopoulou ; M. Koropogui ; A. Kosgey ; E. Kuisma ; C. H. Logue ; A. Mazzarelli ; S. Meisel ; M. Mertens ; J. Michel ; D. Ngabo ; K. Nitzsche ; E. Pallasch ; L. V. Patrono ; J. Portmann ; J. G. Repits ; N. Y. Rickett ; A. Sachse ; K. Singethan ; I. Vitoriano ; R. L. Yemanaberhan ; E. G. Zekeng ; T. Racine ; A. Bello ; A. A. Sall ; O. Faye ; N. Magassouba ; C. V. Williams ; V. Amburgey ; L. Winona ; E. Davis ; J. Gerlach ; F. Washington ; V. Monteil ; M. Jourdain ; M. Bererd ; A. Camara ; H. Somlare ; M. Gerard ; G. Bado ; B. Baillet ; D. Delaune ; K. Y. Nebie ; A. Diarra ; Y. Savane ; R. B. Pallawo ; G. J. Gutierrez ; N. Milhano ; I. Roger ; C. J. Williams ; F. Yattara ; K. Lewandowski ; J. Taylor ; P. Rachwal ; D. J. Turner ; G. Pollakis ; J. A. Hiscox ; D. A. Matthews ; M. K. O'Shea ; A. M. Johnston ; D. Wilson ; E. Hutley ; E. Smit ; A. Di Caro ; R. Wolfel ; K. Stoecker ; E. Fleischmann ; M. Gabriel ; S. A. Weller ; L. Koivogui ; B. Diallo ; S. Keita ; A. Rambaut ; P. Formenty ; S. Gunther ; M. W. Carroll
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-02-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aircraft ; Disease Outbreaks/statistics & numerical data ; Ebolavirus/classification/*genetics/pathogenicity ; *Epidemiological Monitoring ; Genome, Viral/*genetics ; Guinea/epidemiology ; Hemorrhagic Fever, Ebola/*epidemiology/*virology ; Humans ; Mutagenesis/genetics ; Mutation Rate ; Sequence Analysis, DNA/*instrumentation/*methods ; Time FactorsPublished by: -
5Fleischmann, E. ; Marhofer, P. ; Greher, M. ; Waltl, B. ; Sitzwohl, C. ; Kapral, S.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1460-9592Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary Background: Brachial plexus blockade is a well-established technique in upper-limb surgery. In paediatric patients, the axillary route is usually preferred to infraclavicular approaches because of safety considerations. Recent reports on a lateral infraclavicular approach offering greater safety in adults prompted us to perform a prospective randomized study to assess the analgesic efficacy of axillary vs lateral vertical infraclavicular brachial plexus (LVIBP) blocks in paediatric trauma surgery. Methods: Forty paediatric trauma patients (ASA physical status I and II, age range 1–10 years) scheduled for forearm or hand surgery were randomly assigned to either axillary brachial plexus (ABP group) or LVIBP group blocks using 0.5 ml·kg−1 ropivacaine 0.5%. Sensory blockade was evaluated by a visual analogue score and Vester–Andersen's criteria, the distribution of sensory and motor blockade was evaluated by a simplified pinprick test and motor tests. Results: In the LVIBP group, Vester–Andersen's criteria were met by 100% of children, compared with 80% in the ABP group (P=0.035). Based on all assessable children, sensory blockade in the primary sensory regions of various nerves was significantly more effective in the LVIBP group (axillary: P 〈 0.0001; musculocutaneous: P=0.002; medial brachial cutaneous; P=0.008). Motor blockade was also significantly more effective (axillary: P 〈 0.0001; musculocutaneous: P=0.003). No major complications were observed in either group. Discussion: We conclude that LVIBP blocks can be safely performed in children and that they add to the spectrum of sensory and motor blockade seen with the axillary approach.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Makino2 investigated the effect of injecting hydrogen peroxide intraperitoneally into rats which had been inoculated six days previously with Yoshida ascites sarcoma. 2 hr. after an injection of 1 ml. of 2 per cent hydrogen peroxide he found 90 per cent of the tumour cells to be injured; also he ...Type of Medium: Electronic ResourceURL: -
7Puchkova, G. P. ; Prigogina, E. L. ; Fleischmann, E. W. ; Drosdova, T. S. ; Mayakova, S. A. ; Peterson, I. S.
Springer
Published 1983Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Banded chromosomes of leukemic cells were studied in 53 children with chronic myeloid leukemia (CML). Ph1 chromosome was found in 21 children, and the remaining 32 cases were Ph1 negative. Besides Ph1 translocation additional chromosomal abnormalities, including marker i(17q), were revealed in three of eight children studied in blastic crisis of Ph1 positive CML. Leukemic cells of most patients with Ph1 negative CML possessed normal karyotype. Clones with chromosomal abnormalities were found in 12 of 32 cases. Most characteristic were monosomy 7 (in four children) and trisomy 8 (in three). Abnormal karyotype may be a bad prognostic sign in Ph1 negative CML. The presented data confirm the difference in age of appearance, bone marrow pattern and clinical course between Ph1 positive (“adult”) and Ph1 negative (juvenile) types of CML in children. Probable prenatal commencement of CML in babies and children in the first years of life is discussed.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1432-1335Source: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Summary An inhibition of growth could be observed in the Yoshida sarcoma of the rat with the dose of 2 mgm/kg body weight of DHAS. With DHAS and X-irradiation together an effect was observed which was considered to be a summation of the inhibitory effect on tumor growth of each.Notes: Zusammenfassung Am Yoshida-Sarkom der Ratte konnte bei einer Dosis von 2 mg/kg Körpergewicht DHAS eine Wachstumshemmung beobachtet werden. Eine kombinierte Anwendung von DHAS und Röntgenbestrahlungen zeigt einen Effekt, der als eine Summation der tumorwachstumshemmenden Wirkung beider aufzufassen ist.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1591-9528Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Zusammenfassung Es wird erstmalig über durch Applikation von Radiogoldseeds in den Hypothalamus des Meerschweinchens experimentell gesetzte Schäden berichtet. Bereits 40 Std nach der Applikation der Goldseeds kommt es zu einer Totalnekrose des nervösen Gewebes, die zwischen dem 4. und 6. Tag ihre größte, etwa einer Seeddicke (0,8 mm) entsprechende Ausdehnung erreicht. Außen an die Nekrosezone anschließend findet sich eine bis 1 mm breite Ödemzone mit schweren, nur histologisch faßbaren degenerativen Veränderungen an den nervösen Strukturen. Ab dem 14. Tag setzt der Abbau der Nekrose ein, der in einer Cystenbildung endet. Auf Grund der errechneten Radiodosen wird für die Auslösung der Hirngewebsnekrose im Hypothalamus des Meerschweinchens eine Dosis von etwa 30000 r, für die Ödemzone von 7000–20000 r angenommen. Die Nekrose wird als direkte Folge der Strahleneinwirkung aufgefaßt.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1435-1528Keywords: Injection molding ; skin layer ; crystallization kinetics ; chainorientation ; polypropyleneSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyPhysicsDescription / Table of Contents: Abstract The thickness of highly oriented skin layers is determined on 2-mm-thick plates injected under different processing conditions by birefringence measurements. Two technical polypropylene types of different molar mass distributions are used. Measurements on samples injected with and without pressure hold after filling make it possible to decide between chain orientation caused during injection and chain orientation caused by the pressure hold after filling. Different models for the calculation of the oriented layer thickness are discussed. The results reveal that the highly oriented skin layers are already formed during the filling phase and that thickness is probably determined through the opposing development of stress-induced crystallization and relaxation. Further measurements indicate that at the injection molding without pressure hold after filling, the melt can relax between the skin layers and can be strongly supercooled before it crystallizes.Notes: Zusammenfassung An 2 mm dicken unter verschiedenen Bedingungen spritzgegossenen Platten aus zwei Polypropylentypen mit unterschiedlicher Molmassenverteilung wird durch Messung der optischen Doppelbrechung die Dicke der hochorientierten Randschichten bestimmt. Durch solche Messungen an Platten, die mit und ohne Nachdruck gespritzt wurden, lassen sich die während der Füllphase von den während der Nachdruckphase entstandenen Orientierungsanteilen trennen. Möglichkeiten der theoretischen Berechnung der Randschichtdicke werden diskutiert. Hieraus ergibt sich, daß die hochorientierten Randschichten bereits während des Füllvorganges entstehen und deren Dicke vermutlich durch die Konkurrenz zwischen scherinduzierter Kristallisation und Relaxation bestimmt wird. Beim Spritzen ohne Nachdruck kann die Schmelze in der Mitte der Platte zwischen den Randschichten relaxieren und stark unterkühlt werden, bevor sie kristalliert, wie durch zusätzliche Messungen nachgewiesen wurde.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1591-9528Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Zusammenfassung Es wird über eine Methode berichtet, radioaktive Isotope in die Hypothalamusregion des Meerschweinchens zu applizieren. Auf Grund der anatomischen Gegebenheiten wird — als kürzester intrakranialer Weg ohne das übrige Gehirn zu lädieren — durch das Ohr eingegangen. Die Lage des Applikators wird durchleuchtungsmäßig am Bildverstärker kontrolliert. Die Methode wird am Beispiel der Applikation von ein bzw. zwei Goldseeds besprochen.Type of Medium: Electronic ResourceURL: -
12Fleischmann, E. ; Zipper, P. ; Jánosi, A. ; Geymayer, W. ; Koppelmann, J. ; Schurz, J.
Stamford, Conn. [u.a.] : Wiley-Blackwell
Published 1989Staff ViewISSN: 0032-3888Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: The tensile test behavior of specimens taken from polypropylene discs injection-molded with and without packing, respectively, was studied. The initial state of the different layers of the specimens and their stressed state, respectively, are characterized by small-angle X-ray scattering (SAXS), wide-angle X-ray scattering (WAXS), measurements of birefringence and of mechanical properties, and by light-microscopic investigations. The results off these experiments altogether give a detailed representation of the behavior of the different layers of the specimens in the tensile test.Additional Material: 12 Ill.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0021-8995Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: Rectangular plates were injection molded with isotactic polypropylene. At a pressure of 1300 bar the mold was sealed mechanically in the gate. After the injection and compression phase the internal pressure decay has been calculated using the pressure-specific volume-temperature diagram and compared with measurements. The calculation method is described. The pvT diagram determined on stationary melt at a low cooling rate yields no good approximations of the measured values. It is shown which modifications of the pvT diagram are necessary to obtain a better description of the melt behavior under injection molding conditions. At the end of the cooling phase, the calculated pressure differs from the measured pressure. The reason is the volume change of the mold caused by the high internal pressure.Additional Material: 7 Ill.Type of Medium: Electronic ResourceURL: