Search Results - (Author, Cooperation:E. Eich)
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1B. A. Nosek ; G. Alter ; G. C. Banks ; D. Borsboom ; S. D. Bowman ; S. J. Breckler ; S. Buck ; C. D. Chambers ; G. Chin ; G. Christensen ; M. Contestabile ; A. Dafoe ; E. Eich ; J. Freese ; R. Glennerster ; D. Goroff ; D. P. Green ; B. Hesse ; M. Humphreys ; J. Ishiyama ; D. Karlan ; A. Kraut ; A. Lupia ; P. Mabry ; T. A. Madon ; N. Malhotra ; E. Mayo-Wilson ; M. McNutt ; E. Miguel ; E. L. Paluck ; U. Simonsohn ; C. Soderberg ; B. A. Spellman ; J. Turitto ; G. VandenBos ; S. Vazire ; E. J. Wagenmakers ; R. Wilson ; T. Yarkoni
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-06-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Access to Information ; Disclosure ; *Guidelines as Topic ; Peer Review, Research ; Periodicals as Topic/*standards ; *Reproducibility of Results ; Research/*standardsPublished by: -
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ISSN: 0031-9422Keywords: [idt] Convolvulaceae ; [idt] Ipomoea hederifolia ; [idt] ipanguline ; [idt] isoipanguline ; [idt] pyrrolizidine alkaloids ; [idt] turneforcidine diestersSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0031-9422Keywords: Convolvulaceae ; Ipomoea hederifolia ; ipanguline ; isoipanguline. ; pyrrolizidine alkaloids ; turneforcidine diestersSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 0375-9601Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 1432-1912Keywords: 5-HT2 receptors ; Lysergol and dihydrolysergol-I derivatives ; Methysergide ; LY 53857 ; Allosteric modulationSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Twelve ergolines (O-Ayated lysergol and dihydrolysergol-I derivatives) were synthesized to study their antagonism of 5-HT responses in comparison with methysergide and LY 53857 [6-methyl-l-(1-methylethyl)-8β-ergoline carboxylic acid 2-hydroxy-l-methyl-propylester hydrogen maleate] in cylindrical segments of the isolated rat tail artery. With regard to (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate, the most potent new ergoline derivative, we examined the phenomenon of insurmountable antagonism to 5-HT by methysergide. O-Acylated lysergol and dihydrolysergol-I derivatives competitively antagonized 5-HT-induced contractions with calculated pA2. values of 7.30 ± 0.42 for the weakest and 8.42 ± 0.35 for the most potent ergoline derivative in this series. N1-isopropyl substitution did not generally enhance 5-HT2 receptor affinities but lowered affinities for α1 adrenoceptors in rat aorta. Methysergide and LY 53857 were insurmountable, antagonists of 5-HT in rat tail artery. Preincubation with (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate (1 μmol/l) partially prevented the depression of 5-HT-induced contractions caused by methysergide (1–10 nmol/l). Methysergide (100 nmol/l) abolished the protective effect of (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate. (9.10-Didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate (1 μmol/l), concomitantly incubated with methysergide (30 nmol/l), partially restored the maximum response to 5-HT that had been depressed by methysergide (30 nmol/l). Partial restoration could not be mimicked by washout of methysergide. In view of this result, it is suggested that insurmountable antagonism by methysergide of 5-HT responses in rat tail artery is due to allosteric modulation of 5-HT2 receptors rather than pseudoirreversible inhibition.Type of Medium: Electronic ResourceURL: -
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ISSN: 1434-6052Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Starting from a Dirac equation with a scalar linear confinement potential for quarks we calculate the electromagnetic and weak form factors of the nucleon and the magnetic transition form factor of the Δ(1232). Taking the Lorentz transformation of the quark wave functions into account the results compare well with the experimental data.Type of Medium: Electronic ResourceURL: