Search Results - (Author, Cooperation:E. Eich)

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  1. 1
    Staff View
    Publication Date:
    2015-06-27
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Access to Information ; Disclosure ; *Guidelines as Topic ; Peer Review, Research ; Periodicals as Topic/*standards ; *Reproducibility of Results ; Research/*standards
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Jenett-Siems, K. ; Kaloga, M. ; Eich, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0031-9422
    Keywords:
    [idt] Convolvulaceae ; [idt] Ipomoea hederifolia ; [idt] ipanguline ; [idt] isoipanguline ; [idt] pyrrolizidine alkaloids ; [idt] turneforcidine diesters
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Jenett-Siems, K. ; Kaloga, M. ; Eich, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0031-9422
    Keywords:
    Convolvulaceae ; Ipomoea hederifolia ; ipanguline ; isoipanguline. ; pyrrolizidine alkaloids ; turneforcidine diesters
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Baake, M. ; Baake, E. ; Eich, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9601
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Eich, E. ; Beck, F. ; Richter, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Barshay, S. ; Eich, E. ; Sehgal, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Eich, E. ; Sehgal, L.M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Barshay, S. ; Eich, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Pertz, H. ; Eich, E.
    Springer
    Published 1992
    Staff View
    ISSN:
    1432-1912
    Keywords:
    5-HT2 receptors ; Lysergol and dihydrolysergol-I derivatives ; Methysergide ; LY 53857 ; Allosteric modulation
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Twelve ergolines (O-Ayated lysergol and dihydrolysergol-I derivatives) were synthesized to study their antagonism of 5-HT responses in comparison with methysergide and LY 53857 [6-methyl-l-(1-methylethyl)-8β-ergoline carboxylic acid 2-hydroxy-l-methyl-propylester hydrogen maleate] in cylindrical segments of the isolated rat tail artery. With regard to (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate, the most potent new ergoline derivative, we examined the phenomenon of insurmountable antagonism to 5-HT by methysergide. O-Acylated lysergol and dihydrolysergol-I derivatives competitively antagonized 5-HT-induced contractions with calculated pA2. values of 7.30 ± 0.42 for the weakest and 8.42 ± 0.35 for the most potent ergoline derivative in this series. N1-isopropyl substitution did not generally enhance 5-HT2 receptor affinities but lowered affinities for α1 adrenoceptors in rat aorta. Methysergide and LY 53857 were insurmountable, antagonists of 5-HT in rat tail artery. Preincubation with (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate (1 μmol/l) partially prevented the depression of 5-HT-induced contractions caused by methysergide (1–10 nmol/l). Methysergide (100 nmol/l) abolished the protective effect of (9.10-didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate. (9.10-Didehydro-6-methyl-8β-ergoline)methyl R,S-2-methylbutyrate (1 μmol/l), concomitantly incubated with methysergide (30 nmol/l), partially restored the maximum response to 5-HT that had been depressed by methysergide (30 nmol/l). Partial restoration could not be mimicked by washout of methysergide. In view of this result, it is suggested that insurmountable antagonism by methysergide of 5-HT responses in rat tail artery is due to allosteric modulation of 5-HT2 receptors rather than pseudoirreversible inhibition.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Eich, E.
    Springer
    Published 1988
    Staff View
    ISSN:
    1434-6052
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Starting from a Dirac equation with a scalar linear confinement potential for quarks we calculate the electromagnetic and weak form factors of the nucleon and the magnetic transition form factor of the Δ(1232). Taking the Lorentz transformation of the quark wave functions into account the results compare well with the experimental data.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses