Search Results - (Author, Cooperation:E. Chun)
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1Latest Papers from Table of Contents or Articles in PressW. Liu ; E. Chun ; A. A. Thompson ; P. Chubukov ; F. Xu ; V. Katritch ; G. W. Han ; C. B. Roth ; L. H. Heitman ; I. J. AP ; V. Cherezov ; R. C. Stevens
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-07-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine A2 Receptor Agonists/metabolism ; Adenosine A2 Receptor Antagonists/metabolism ; Allosteric Regulation ; Cholesterol/chemistry ; Crystallography, X-Ray ; Cytochrome b Group/chemistry ; Escherichia coli Proteins/chemistry ; HEK293 Cells ; Humans ; Hydrogen Bonding ; Ligands ; Lipid Bilayers ; Lipids/chemistry ; Models, Molecular ; Protein Conformation ; Protein Engineering ; Protein Structure, Secondary ; Receptor, Adenosine A2A/*chemistry/*metabolism ; Recombinant Fusion Proteins/chemistry/metabolism ; Sodium/*analysis ; Triazines/metabolism ; Triazoles/metabolism ; Water/chemistryPublished by: -
2Latest Papers from Table of Contents or Articles in PressA. A. Thompson ; W. Liu ; E. Chun ; V. Katritch ; H. Wu ; E. Vardy ; X. P. Huang ; C. Trapella ; R. Guerrini ; G. Calo ; B. L. Roth ; V. Cherezov ; R. C. Stevens
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-05-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites ; Biomimetic Materials/*chemistry/metabolism/pharmacology ; Crystallography, X-Ray ; HEK293 Cells ; Humans ; Ligands ; Models, Molecular ; Narcotic Antagonists ; Opioid Peptides/*chemistry/metabolism/pharmacology ; Piperidines/*chemistry/*metabolism/pharmacology ; Protein Conformation ; Receptors, Opioid/*chemistry/*metabolism ; Receptors, Opioid, kappa/chemistry/metabolism ; Spiro Compounds/*chemistry/*metabolism/pharmacology ; Substrate SpecificityPublished by: -
3Latest Papers from Table of Contents or Articles in PressPark, Y. S., Lee, C.-H., Kim, Y.-I., Ahn, C. M., Kim, J. O., Park, J.-H., Lee, S. H., Kim, J. Y., Chun, E. M., Jung, T.-H., Yoo, K.-H.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-05-16Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Smoking and tobaccoPublished by: -
4Latest Papers from Table of Contents or Articles in PressLee, S.-E., Sung, J. M., Rizvi, A., Lin, F. Y., Kumar, A., Hadamitzky, M., Kim, Y.-J., Conte, E., Andreini, D., Pontone, G., Budoff, M. J., Gottlieb, I., Lee, B. K., Chun, E. J., Cademartiri, F., Maffei, E., Marques, H., Leipsic, J. A., Shin, S., Hyun Choi, J., Chinnaiyan, K., Raff, G., Virmani, R., Samady, H., Stone, P. H., Berman, D. S., Narula, J., Shaw, L. J., Bax, J. J., Min, J. K., Chang, H.-J.
American Heart Association (AHA)
Published 2018Staff ViewPublication Date: 2018-07-18Publisher: American Heart Association (AHA)Print ISSN: 1941-9651Electronic ISSN: 1942-0080Topics: MedicineKeywords: Computerized Tomography (CT), PrognosisPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-06-03Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
6Articles: DFG German National LicensesChen, James M. ; Kung, Chun E. ; Feairheller, Stephen H. ; Brown, Eleanor M.
Springer
Published 1991Staff ViewISSN: 1573-4943Keywords: Triple helix ; fibril ; coiled-coil ; telopeptide ; cross-linking, molecular modelingSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract An energy minimized three-dimensional structure of a collagen microfibril template was constructed based on the five-stranded model of Smith (1968), using molecular modeling methods and Kollman force fields (Weiner and Kollman, 1981). For this model, individual molecules were constructed with three identical polypeptide chains ((Gly-Pro-Pro) n , (Gly-Prop-Hyp) n , or (Gly-Ala-Ala) n , wheren=4, 12, and 16) coiled into a right-handed triple-helical structure. The axial distance between adjacent amino acid residues is about 0.29 nm per polypeptide chain, and the pitch of each chain is approximately 3.3 residues. The microfibril model consists of five parallel triple helices packed so that a left-handed superhelical twist exists. The structural characteristics of the computed microfibril are consistent with those obtained for collagen by X-ray diffraction and electron microscopy. The energy minimized Smith microfibril model for (Gly-Pro-Pro)12 has an axial length of about 10.2 nm (for a 36 amino acid residue chain), which gives an estimated D-spacing (234 amino acids per chain) of approximately 66.2 nm. Studies of the microfibril models (Gly-Pro-Pro)12, (Gly-Pro-Hyp)12, and (Gly-Ala-Ala)12 show that nonbonded van der Waals interactions are important for microfibril formation, while electrostatic interactions contribute to the stability of the microfibril structure and determine the specificity by which collagen molecules pack within the microfibril.Type of Medium: Electronic ResourceURL: