Search Results - (Author, Cooperation:D. Ratner)
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1Latest Papers from Table of Contents or Articles in PressS. Li, F. Cropp, K. Kabra, T. J. Lane, G. Wetzstein, P. Musumeci, and D. Ratner
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-09-12Publisher: American Physical Society (APS)Print ISSN: 0031-9007Electronic ISSN: 1079-7114Topics: PhysicsKeywords: Plasma and Beam PhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressD. Milathianaki ; S. Boutet ; G. J. Williams ; A. Higginbotham ; D. Ratner ; A. E. Gleason ; M. Messerschmidt ; M. M. Seibert ; D. C. Swift ; P. Hering ; J. Robinson ; W. E. White ; J. S. Wark
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-10-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressOrning, P., Weng, D., Starheim, K., Ratner, D., Best, Z., Lee, B., Brooks, A., Xia, S., Wu, H., Kelliher, M. A., Berger, S. B., Gough, P. J., Bertin, J., Proulx, M. M., Goguen, J. D., Kayagaki, N., Fitzgerald, K. A., Lien, E.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: ImmunologyPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesBenedict, M. A. ; Desilver, D. A. ; Pelletier, D. E. ; Pentz, W. H. ; Ratner, D. I.
Chichester [u.a.] : Wiley-Blackwell
Published 1991Staff ViewISSN: 0192-253XKeywords: Dictyostelium discoideum ; cyclo heximide ; emetine ; protein synthesis ; mRNA accu mulation ; transcription ; Life and Medical Sciences ; GeneticsSource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyNotes: It has been established previ- ously that the maintenance of expression of pre-spore-specific genes of Dictyostelium discoideum is prevented by the translational inhibitor cyclohex- imide. The drug had no effect upon the level of transcripts of the other genes examined, prestalk-specific or cell type-nonspecific. However, the interpretation of this result is open to question, because of possible nonspecific effects of cyclo-heximide. We have now characterized the cellular specificity and temporal profiles of mRNA accumu- lation of additional Dictyostelium cDNA clones, and have examined other inhibitors of in vivo protein synthesis. Four structurally and mechanistically distinct translational inhibitors each prevented the reaccumulation of prespore transcripts in cyclic AMP-primed, disaggregated amoebae. These results establish the importance of developmental protein synthesis in the accumulation of prespore gene transcripts. Nuclear run-on transcription assays were used to learn whether protein synthesis is required primarily for mRNA synthesis or transcript stability. A transcriptional time course first demonstrated that the abundance of these cell-specific transcripts during development mirrors their rates of synthesis. Significantly, the protein synthesis requirement of the prespore genes examined also occurs at the level of mRNA transcription, implying the existence of one or more developmentally regulated transcriptional activators.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: