Search Results - (Author, Cooperation:D. R. Lowy)
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1Latest Papers from Table of Contents or Articles in PressF. S. Collins ; J. M. Anderson ; C. P. Austin ; J. F. Battey ; L. S. Birnbaum ; J. P. Briggs ; J. A. Clayton ; B. Cuthbert ; R. W. Eisinger ; A. S. Fauci ; J. I. Gallin ; G. H. Gibbons ; R. I. Glass ; M. M. Gottesman ; P. A. Gray ; E. D. Green ; F. B. Greider ; R. Hodes ; K. L. Hudson ; B. Humphreys ; S. I. Katz ; G. F. Koob ; W. J. Koroshetz ; M. S. Lauer ; J. R. Lorsch ; D. R. Lowy ; J. J. McGowan ; D. M. Murray ; R. Nakamura ; A. Norris ; E. J. Perez-Stable ; R. I. Pettigrew ; W. T. Riley ; G. P. Rodgers ; P. A. Sieving ; M. J. Somerman ; C. Y. Spong ; L. A. Tabak ; N. D. Volkow ; E. L. Wilder
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biomedical Research/*economics ; Humans ; National Institutes of Health (U.S.)/*economicsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: summary The degree of resistance to vesicular stomatitis virus (VSV) increased with the time of contact of chick embryo cells with interferon at 37°C. Resistance developed in cells which were held in contact with interferon at 4°C for an hour, washed free of interferon and then incubated at 37°C before inoculation. The degree of resistance that developed after such treatment was lower than that formed when both the contact with interferon as well as further incubation were performed at 37°C. Increased time of contact with interferon at 4°C led to increased protection. This is considered evidence that the resistance developed after treatment at 4°C was not due to residual unbound interferon carried over to 37°C. Instead it must have been the result of some kind of interaction between interferon and cells taking place at 4°C. Incubation of cells with interferon in the presence of dimethylsulfoxide (DMSO) not only failed to increase, but even significantly decreased, the degree of resistance. Incubation of cells with a high concentration of fetal calf serum (FCS) inhibited the action of interferon and increased the yield of VSV.Type of Medium: Electronic ResourceURL: