Search Results - (Author, Cooperation:D. O'Connor)

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  1. 1
  2. 2
    K. N. Crabtree ; M. R. Talipov ; O. Martinez, Jr. ; G. D. O'Connor ; S. L. Khursan ; M. C. McCarthy
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-12-18
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    F. J. Rodriguez-Fortuno ; G. Marino ; P. Ginzburg ; D. O'Connor ; A. Martinez ; G. A. Wurtz ; A. V. Zayats
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-04-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2012-05-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    African Americans/*genetics ; Disease/genetics ; European Continental Ancestry Group/*genetics ; *Evolution, Molecular ; *Exome ; Female ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; *Genetic Variation ; *Genome, Human ; *High-Throughput Nucleotide Sequencing ; Humans ; Male ; *Polymorphism, Single Nucleotide ; Population Growth ; Selection, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    A. Scally ; J. Y. Dutheil ; L. W. Hillier ; G. E. Jordan ; I. Goodhead ; J. Herrero ; A. Hobolth ; T. Lappalainen ; T. Mailund ; T. Marques-Bonet ; S. McCarthy ; S. H. Montgomery ; P. C. Schwalie ; Y. A. Tang ; M. C. Ward ; Y. Xue ; B. Yngvadottir ; C. Alkan ; L. N. Andersen ; Q. Ayub ; E. V. Ball ; K. Beal ; B. J. Bradley ; Y. Chen ; C. M. Clee ; S. Fitzgerald ; T. A. Graves ; Y. Gu ; P. Heath ; A. Heger ; E. Karakoc ; A. Kolb-Kokocinski ; G. K. Laird ; G. Lunter ; S. Meader ; M. Mort ; J. C. Mullikin ; K. Munch ; T. D. O'Connor ; A. D. Phillips ; J. Prado-Martinez ; A. S. Rogers ; S. Sajjadian ; D. Schmidt ; K. Shaw ; J. T. Simpson ; P. D. Stenson ; D. J. Turner ; L. Vigilant ; A. J. Vilella ; W. Whitener ; B. Zhu ; D. N. Cooper ; P. de Jong ; E. T. Dermitzakis ; E. E. Eichler ; P. Flicek ; N. Goldman ; N. I. Mundy ; Z. Ning ; D. T. Odom ; C. P. Ponting ; M. A. Quail ; O. A. Ryder ; S. M. Searle ; W. C. Warren ; R. K. Wilson ; M. H. Schierup ; J. Rogers ; C. Tyler-Smith ; R. Durbin
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-03-09
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Evolution, Molecular ; Female ; Gene Expression Regulation ; *Genetic Speciation ; Genetic Variation/genetics ; Genome/*genetics ; Genomics ; Gorilla gorilla/*genetics ; Humans ; Macaca mulatta/genetics ; Molecular Sequence Data ; Pan troglodytes/genetics ; Phylogeny ; Pongo/genetics ; Proteins/genetics ; Sequence Alignment ; Species Specificity ; Transcription, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2012-12-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa/ethnology ; African Continental Ancestry Group/genetics ; Alleles ; Europe/ethnology ; European Continental Ancestry Group/genetics ; *Evolution, Molecular ; Exome/*genetics ; Exons/genetics ; Genetic Variation/*genetics ; Humans ; Open Reading Frames/*genetics ; Polymorphism, Single Nucleotide/genetics ; United States
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2014-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Benzamides/pharmacology/therapeutic use ; Clone Cells/drug effects/metabolism/pathology ; Diphenylamine/analogs & derivatives/pharmacology/therapeutic use ; Down-Regulation/drug effects ; *Drug Resistance, Neoplasm/drug effects/genetics ; Drug Synergism ; Genes, ras/genetics ; Indazoles/*pharmacology/therapeutic use ; Male ; Mice ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Phosphatidylinositol 3-Kinases/*antagonists & inhibitors ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug ; therapy/*genetics/metabolism/pathology ; Protein Kinase Inhibitors/*pharmacology/therapeutic use ; Protein Structure, Tertiary ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, Notch1/chemistry/deficiency/genetics/*metabolism ; Signal Transduction/drug effects ; Sulfonamides/*pharmacology/therapeutic use
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    J. Prado-Martinez ; P. H. Sudmant ; J. M. Kidd ; H. Li ; J. L. Kelley ; B. Lorente-Galdos ; K. R. Veeramah ; A. E. Woerner ; T. D. O'Connor ; G. Santpere ; A. Cagan ; C. Theunert ; F. Casals ; H. Laayouni ; K. Munch ; A. Hobolth ; A. E. Halager ; M. Malig ; J. Hernandez-Rodriguez ; I. Hernando-Herraez ; K. Prufer ; M. Pybus ; L. Johnstone ; M. Lachmann ; C. Alkan ; D. Twigg ; N. Petit ; C. Baker ; F. Hormozdiari ; M. Fernandez-Callejo ; M. Dabad ; M. L. Wilson ; L. Stevison ; C. Camprubi ; T. Carvalho ; A. Ruiz-Herrera ; L. Vives ; M. Mele ; T. Abello ; I. Kondova ; R. E. Bontrop ; A. Pusey ; F. Lankester ; J. A. Kiyang ; R. A. Bergl ; E. Lonsdorf ; S. Myers ; M. Ventura ; P. Gagneux ; D. Comas ; H. Siegismund ; J. Blanc ; L. Agueda-Calpena ; M. Gut ; L. Fulton ; S. A. Tishkoff ; J. C. Mullikin ; R. K. Wilson ; I. G. Gut ; M. K. Gonder ; O. A. Ryder ; B. H. Hahn ; A. Navarro ; J. M. Akey ; J. Bertranpetit ; D. Reich ; T. Mailund ; M. H. Schierup ; C. Hvilsom ; A. M. Andres ; J. D. Wall ; C. D. Bustamante ; M. F. Hammer ; E. E. Eichler ; T. Marques-Bonet
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-07-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa ; Animals ; Animals, Wild/genetics ; Animals, Zoo/genetics ; Asia, Southeastern ; Evolution, Molecular ; Gene Flow/genetics ; *Genetic Variation ; Genetics, Population ; Genome/genetics ; Gorilla gorilla/classification/genetics ; Hominidae/classification/*genetics ; Humans ; Inbreeding ; Pan paniscus/classification/genetics ; Pan troglodytes/classification/genetics ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Population Density
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Staff View
    Publication Date:
    2018-08-02
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Fang, Z. ; O'Connor, D. J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1997
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    In this article we present some basic considerations in the design of a time detector for high energy (0.2–1.0 MeV) particle detection. Based on these considerations, a novel time detector design is proposed in order to overcome some of the problems in existing designs. Improvement in the timing resolution (〈50 ps) and efficiency (〉70% for 4.0 MeV α particles) is expected and a compact detector structure with ultrahigh vacuum compatibility is achieved. The new design employs a novel form of crossed electric and magnetic fields to deflect the electrons emitted from a thin foil to form a timing signal. In this design electrons are transported in a grid-free region and the energetic particle needs to pass through the grid once only. The electric field was produced by three metal plates forming a triangular prism. The magnetic field was generated by a coil pair which creates a uniform field in the electron transport region. Computer simulation and numerical analysis were performed to calculate the electric and magnetic field as well as the electron trajectory and flight time. The detector timing resolution is analyzed and the spread in electron initial energy contributes a significant portion. To avoid the complicated numerical details in field and trajectory calculations, we use an empirical approach in this article to illustrate the design principle. Some experimental results are presented to compare with the calculations. © 1997 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    O'Connor, D. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1982
    Staff View
    ISSN:
    1467-9752
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Education
    Philosophy
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    O'Connor, D. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1972
    Staff View
    ISSN:
    1467-9752
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Education
    Philosophy
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    McKenna, D.B. ; O'Connor, D. ; Kay, E. ; Leader, M. ; Murphy, G.M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1997
    Staff View
    ISSN:
    1468-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Papillomaviruses are the causative agents of the common wart. Although the human papillomavirus is strongly associated with certain dysplastic and malignant lesions, its exact role in tumour development remains to be determined. This review examines the role of human papilloma virus as a potential oncogenic agent in human mucosal and non-mucosal squamous cell carcinoma.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Gröntoft, M. ; O'Connor, D.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1439-0523
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Small differences in attack of Alternaria brassicae on Brassica species are difficult to detect in the field. Therefore, a more detailed method was developed in the greenhouse. Small agar discs with Alternaria brassicae were placed with the infected sides against the upper side of the 2nd leaf, over a 4 mm hole. The necrotic lesions on the leaves were measured 7 days after inoculation. The test results indicate that differences in resistance do exist. It is, however, doubtful if the resistance is great enough to be used in a plant breeding programme.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    O'Connor, D. ; Longhorn, R. ; Heard, A.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Alford, N. McN. ; Button, T. W. ; Gough, C. E. ; Wellhofer, F. ; O'Connor, D. A. ; Colclough, M. S. ; Pollard, R. J. ; McCartney, D. G.

    [S.l.] : American Institute of Physics (AIP)
    Published 1989
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    For bulk applications, high-Tc superconductors generally require high critical current density, Jc. This paper reports two methods of producing high-Tc ceramic wires. The first is an extrusion and sintering route where Jc is routinely 600–1000 A cm−2. The second is by melt texturing or directional solidification where we have achieved in excess of 7000 A cm−2 by direct measurement at 77 K in zero field. However, the ease with which wire may be extruded and sintered is attractive and functioning devices have already been manufactured using this route. Fabrication of devices is facilitated by a unique processing route that has resulted in the strongest bulk ceramic yet reported (bend strength 〉200 MPa). The melt-texturing route and the problems associated with it are examined and compared with the extrusion and sintering route. The processing and the microstructures associated with the directionally solidified YBa2Cu3Ox will be examined in detail as will the resultant superconducting properties, in particular the magnetization.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    MAUDE, R. B. ; SHIPWAY, M. R. ; PRESLY, A. H. ; O'CONNOR, D.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1984
    Staff View
    ISSN:
    1365-3059
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Direct harvesting, with mechanical removal of the foliage (topping), of onion crops followed by post-harvest drying at ambient temperatures (c. 18°C) resulted in an increase in the incidence of onion neck rot (Botrytis allii).The disease was substantially reduced if topped onions were dried at 30°C with an airflow of 425 m3 air/h/tonne. The treatment was most effective if the crop was removed from the field for drying within 48 h of topping thus avoiding severe infection of the damaged green tissues of the necks of onions.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Sukupolvi, S. ; Vuorio, R. ; Qi, S.-Y. ; O'Connor, D. ; Rhen, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The nucieotide sequence of the traT gene present in the virulence-associated pfasmid of Salmonella typhimurium was determined. The predicted TraT protein encoded by this gene was found to consist of 243 amino acids and to resemble the known TraT proteins of the plasmids of the F incompatibility group. Thus it contains a signal sequence of 20 amino acids, an amino-terminal lipid attachment site, and two strongly hydrophobic regions close to each other in the mature protein. A mutation leading to increased permeability of the outer membrane to hydrophobic agents, previousfy focalrzed to the traT gene, was shown to change a glycine residue to arginine within one of these hydrophobic regions. The same principle was found to apply to TraT of R6-5: the introduction, by site-directed mutagenesis, of either positively or negatively charged amino acids or the helix-disrupting proline in the corresponding hydrophobic region led to increased hydrophobic permeability of the outer membrane.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20