Search Results - (Author, Cooperation:D. McKenna)

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  1. 1
    Staff View
    Publication Date:
    2011-06-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-07-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Actins/metabolism ; Amino Acid Sequence ; Amyotrophic Lateral Sclerosis/diagnosis/*genetics/metabolism/*pathology ; Animals ; Axons/metabolism/pathology ; Cells, Cultured ; European Continental Ancestry Group/genetics ; Exome/genetics ; Female ; Genetic Predisposition to Disease/*genetics ; Growth Cones/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Jews/genetics ; Male ; Mice ; Models, Molecular ; Molecular Sequence Data ; Motor Neurons/cytology/metabolism ; Mutant Proteins/genetics/*metabolism ; Mutation/*genetics ; Pedigree ; Profilins/*genetics/*metabolism ; Protein Conformation ; Ubiquitination
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    B. Misof ; S. Liu ; K. Meusemann ; R. S. Peters ; A. Donath ; C. Mayer ; P. B. Frandsen ; J. Ware ; T. Flouri ; R. G. Beutel ; O. Niehuis ; M. Petersen ; F. Izquierdo-Carrasco ; T. Wappler ; J. Rust ; A. J. Aberer ; U. Aspock ; H. Aspock ; D. Bartel ; A. Blanke ; S. Berger ; A. Bohm ; T. R. Buckley ; B. Calcott ; J. Chen ; F. Friedrich ; M. Fukui ; M. Fujita ; C. Greve ; P. Grobe ; S. Gu ; Y. Huang ; L. S. Jermiin ; A. Y. Kawahara ; L. Krogmann ; M. Kubiak ; R. Lanfear ; H. Letsch ; Y. Li ; Z. Li ; J. Li ; H. Lu ; R. Machida ; Y. Mashimo ; P. Kapli ; D. D. McKenna ; G. Meng ; Y. Nakagaki ; J. L. Navarrete-Heredia ; M. Ott ; Y. Ou ; G. Pass ; L. Podsiadlowski ; H. Pohl ; B. M. von Reumont ; K. Schutte ; K. Sekiya ; S. Shimizu ; A. Slipinski ; A. Stamatakis ; W. Song ; X. Su ; N. U. Szucsich ; M. Tan ; X. Tan ; M. Tang ; J. Tang ; G. Timelthaler ; S. Tomizuka ; M. Trautwein ; X. Tong ; T. Uchifune ; M. G. Walzl ; B. M. Wiegmann ; J. Wilbrandt ; B. Wipfler ; T. K. Wong ; Q. Wu ; G. Wu ; Y. Xie ; S. Yang ; Q. Yang ; D. K. Yeates ; K. Yoshizawa ; Q. Zhang ; R. Zhang ; W. Zhang ; Y. Zhang ; J. Zhao ; C. Zhou ; L. Zhou ; T. Ziesmann ; S. Zou ; X. Xu ; H. Yang ; J. Wang ; K. M. Kjer ; X. Zhou
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-11-08
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Genetic Code ; Genome, Insect ; Genomics ; Insect Proteins/*classification/genetics ; Insects/*classification/genetics ; *Phylogeny ; Time Factors
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    E. T. Cirulli ; B. N. Lasseigne ; S. Petrovski ; P. C. Sapp ; P. A. Dion ; C. S. Leblond ; J. Couthouis ; Y. F. Lu ; Q. Wang ; B. J. Krueger ; Z. Ren ; J. Keebler ; Y. Han ; S. E. Levy ; B. E. Boone ; J. R. Wimbish ; L. L. Waite ; A. L. Jones ; J. P. Carulli ; A. G. Day-Williams ; J. F. Staropoli ; W. W. Xin ; A. Chesi ; A. R. Raphael ; D. McKenna-Yasek ; J. Cady ; J. M. Vianney de Jong ; K. P. Kenna ; B. N. Smith ; S. Topp ; J. Miller ; A. Gkazi ; A. Al-Chalabi ; L. H. van den Berg ; J. Veldink ; V. Silani ; N. Ticozzi ; C. E. Shaw ; R. H. Baloh ; S. Appel ; E. Simpson ; C. Lagier-Tourenne ; S. M. Pulst ; S. Gibson ; J. Q. Trojanowski ; L. Elman ; L. McCluskey ; M. Grossman ; N. A. Shneider ; W. K. Chung ; J. M. Ravits ; J. D. Glass ; K. B. Sims ; V. M. Van Deerlin ; T. Maniatis ; S. D. Hayes ; A. Ordureau ; S. Swarup ; J. Landers ; F. Baas ; A. S. Allen ; R. S. Bedlack ; J. W. Harper ; A. D. Gitler ; G. A. Rouleau ; R. Brown ; M. B. Harms ; G. M. Cooper ; T. Harris ; R. M. Myers ; D. B. Goldstein
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-02-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptor Proteins, Signal Transducing/genetics/metabolism ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Amyotrophic Lateral Sclerosis/*genetics ; Autophagy/*genetics ; Exome/*genetics ; Female ; Genes ; Genetic Association Studies ; *Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Protein Binding ; Protein-Serine-Threonine Kinases/*genetics/metabolism ; Risk ; Sequence Analysis, DNA ; Transcription Factor TFIIIA/genetics/metabolism ; Young Adult
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2015-08-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Insect Proteins/*classification ; Insects/*classification ; *Phylogeny
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Oh, C. C. Y. ; McKenna, D. B. ; McLaren, K. M. ; Tidman, M. J.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2230
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We report a case of factitious panniculitis masquerading as florid pyoderma gangrenosum in a 35-year-old woman. At presentation, she had tender, ecchymotic plaques over the lower trunk and limbs, and several biopsies showed active lobular panniculitis. However, the extensive ulceration that ensued was clinically persuasive for pyoderma gangrenosum. We elected to treat the inflammatory element symptomatically with a range of topical and systemic medications including clobetasol propionate, tacrolimus 0.1% ointment, prednisolone, dapsone, cyclosporin A and mycophenolate mofetil, none of which effected an improvement. The possibility of a factitious aetiology had been suspected from the outset, and when signs of clinical depression emerged, antidepressant therapy was initiated and the ulcers were encased in fibreglass casts. Within a short period, healing commenced and slowly progressed with scar formation. In retrospect, we consider the diagnosis to have been factitious panniculitis on the basis of strong circumstantial evidence and the disparity between the histological and clinical features.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2230.2004.01713.x

    Articles: DFG German National Licenses
  7. 7
    McKENNA, D. R. ; STRACHAN, D. S. ; MILLER, R. K. ; ACUFF, G. R. ; SAVELL, J. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2003
    Staff View
    ISSN:
    1745-4573
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Marination was investigated as a means to add value and improve the palatability of lamb chops. Vacuum-packaged whole lamb loins (n = 24) were assigned randomly to a 14 or 20-day aging period. Loins were split and right and left sides were designated to receive one of two treatments: control or marinade with spice rub. Loins were cut into chops and chops were vacuum-packaged and displayed for 0–, 7– or 14-days in a retail display case. Chops from both aging periods assigned to the 0 day retail display period were evaluated for both raw and cooked characteristics by consumers. Consumers indicated that cooked appearance. odor, juiciness, flavor, tenderness, and overall-like were higher for treated chops than for controls (P 〈 0.05). However, consumers preferred the appearance of raw control chops over the appearance of raw treated chops (P 〈 0.05). Treated lamb chops had lower aerobic plate counts at 7 and 14 days of retail display for both aging periods (P 〈 0.05), and lower 2-thiobarbituric acid (TBARS) values than control chops (P 〈 0.05). A treatment × retail display day interaction (P 〈 0.05) was observed for TBARS values as treated chops had lower TBARS values than control chops as days of retail display increased. Marinating lamb chops improved palatability traits of cooked lamb chops and extended the shelf-life characteristics of raw lamb chops.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1745-4573.2003.tb00701.x

    Articles: DFG German National Licenses
  8. 8
    McKENNA, D. R. ; MORRIS, C. A. ; KEETON, J. T. ; MILLER, R. K. ; HALE, D. S. ; HARRIS, S. D. ; SAVELL, J. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2003
    Staff View
    ISSN:
    1745-4573
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Two value-added ostrich meat product prototypes were prepared and evaluated by a consumer panel (n = 132) against similar products manufactured entirely from pork. Ostrich “ham” and a control pork ham product were prepared by a traditional ham cure, and Polish sausage products were formulated with either all-pork or a 67% ostrich/33 % pork blend and processed with a commercial spice blend. Ostrich “ham“ tended to be rated lower (P = 0.0537) in salt intensity, but had higher flavor intensity ratings. Consumers gave pork ham more favorable ratings for overall acceptability (P〈 0.01) and flavor acceptability (P〈 0.05). For Polish sausage products, overall acceptability, flavor acceptability, flavor intensity, salt intensity, texture and tenderness were not different (P 〉 0.05) between all-pork and ostrich/pork varieties. Results indicate that value-added ostrich meat products were more acceptable when they were more finely ground, spiced, and combined with pork in a sausage product than when they were prepared as a “ham“ product.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1745-4573.2003.tb00698.x

    Articles: DFG German National Licenses
  9. 9
    McKenna, D. B. ; Murphy, G. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1600-0536
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0536.1998.tb05675.x

    Articles: DFG German National Licenses
  10. 10
    Lenane, P. ; McKenna, D. ; Murphy, G. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1600-0536
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0536.1998.tb05734.x

    Articles: DFG German National Licenses
  11. 11
    McKenna, D. B. ; Cooper, E. J. ; Kavanagh, G. M. ; Davie, R. M. ; McLaren, K. M. ; Tidman, M. J.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2230
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Cryosurgery is an alternative treatment option to surgical excision for lentigo maligna. Clinical evidence of recurrence is usually characterized by repigmentation at the treated site. We report two patients who developed amelanotic malignant melanoma following cryosurgery for a pigmented lentigo maligna. These cases illustrate the potential risk of treating lentigo maligna with cryosurgery.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2230.2000.00716.x

    Articles: DFG German National Licenses
  12. 12
    Mansfield, J. C. ; Giaffer, M. H. ; Cann, P. A. ; Mckenna, D. ; Thornton, P. C. ; Holdsworth, C. D.

    Oxford UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Sulfasalazine is accepted therapy for active ulcerative colitis, but side-effects and intolerance are common. Balsalazide is an azo-bonded pro-drug which also releases 5-aminosalicylic acid into the colon, but uses an inert carrier molecule.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:To compare the safety and efficacy of sul- fasalazine, 3 g, with balsalazide, 6.75 g, in the initial daily treatment of mild to moderate ulcerative colitis.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:A randomized, multicentre, double-blind, parallel group study was performed, with a treatment duration of 8 weeks. Patients on previous maintenance treatment were excluded. The trial medication was the sole treatment for the colitis. Efficacy was assessed by patient diaries, symptom assessment, sigmoidoscopic appearance and histology.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Fifty patients were recruited: 26 allocated to the balsalazide group and 24 to the sulfasalazine group. More patients withdrew due to adverse events in the sulfasalazine group (nine patients vs. one patient in the balsalazide group, P=0.004). Improvement occurred in both groups, with a tendency to a faster response with balsalazide. Of the patients taking balsalazide, 61% achieved clinical and sigmoidoscopic remission.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Balsalazide, 6.75 g, is effective as the sole treatment for patients with mild to moderately active ulcerative colitis, with significantly fewer withdrawals due to side-effects than in a similar group of patients taking sulfasalazine, 3 g.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2036.2002.01151.x

    Articles: DFG German National Licenses
  13. 13
    COGHLAN, J. ; HUTCHINSON, L. ; GILLIGAN, D. ; McKENNA, D. ; KEANE, C. ; SWEENEY, E. ; O'MORAIN, C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Sixty consecutive patients with endoscopically proven duodenal ulcers were given colloidal bismuth subcitrate tablets either as 120 mg q.d.s. or 240 mg b.d., in a randomized single-blind study. The efficacy of each regimen was determined by endoscopic examination and antral biopsy at 4 weeks; if the ulcer remained unhealed, treatment was continued and endoscopy repeated at 8 weeks. The ulcer-healing efficacy of the two regimens was identical; however, in the four times daily group only 27% remained Campylobacter pylori positive after 8 weeks of treatment compared with 58% of the twice-daily group. Similarly, only 21% of twice daily patients were free of histological gastritis compared with 42% of the four times daily patients.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2036.1990.tb00448.x

    Articles: DFG German National Licenses
  14. 14
    Lee, P. ; McKenna, D. ; Kapur, D. ; Jensen, K.F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0248
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Geosciences
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-0248(86)90291-5

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0093-691X
    Keywords:
    cow ; estrous cycle ; pressure ; uterus
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0093-691X(87)90222-6

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0093-691X
    Keywords:
    adrenoceptor blockers ; cow ; estrous cycle ; intrauterine pressure
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0093-691X(87)90224-X

    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    0093-691X
    Keywords:
    cow ; pressure ; prostaglandins ; uterus
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0093-691X(87)90223-8

    Articles: DFG German National Licenses
  18. 18
    Johnson, D. W. ; Kilsby, C. G. ; McKenna, D. S. ; Saunders, R. W. ; Jenkins, G. J. ; Smith, F. B. ; Foot, J. S.

    [s.l.] : Nature Publishing Group
    Published 1991
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Airborne measurements in the densest part of the smoke plume at about 120km from the burning wells in Kuwait in late March 1991 showed typical particulate mass densities of 500–1,000 µgm−3, mixing ratios of 500–1,000 p.p.b.v. of sulphur dioxide and 30–60 ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/353617a0

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Model calculations, constrained by satellite observations, indicate that most of the smoke from the oil fires in Kuwait will remain in the lowest few kilometres of the troposphere. Beneath the plume there is a severe reduction in daylight, and a day-time temperature drop of ~10 °C within ~200 ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/351363a0

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0992-7689
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Geosciences
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s00585-999-0437-2

    Articles: DFG German National Licenses