Search Results - (Author, Cooperation:D. M. Martin)
-
1Latest Papers from Table of Contents or Articles in PressJ. L. Van Nostrand ; C. A. Brady ; H. Jung ; D. R. Fuentes ; M. M. Kozak ; T. M. Johnson ; C. Y. Lin ; C. J. Lin ; D. L. Swiderski ; H. Vogel ; J. A. Bernstein ; T. Attie-Bitach ; C. P. Chang ; J. Wysocka ; D. M. Martin ; L. D. Attardi
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Abnormalities, Multiple/genetics/*metabolism ; Alleles ; Animals ; Apoptosis/genetics ; CHARGE Syndrome/*genetics/*metabolism ; Cell Cycle Checkpoints/genetics ; Craniofacial Abnormalities/genetics/metabolism ; DNA-Binding Proteins/deficiency/genetics/metabolism ; Ear/abnormalities ; Embryo, Mammalian/abnormalities/metabolism ; Female ; Fibroblasts ; Gene Deletion ; Heterozygote ; Humans ; Male ; Mice ; Mutant Proteins/metabolism ; *Phenotype ; Promoter Regions, Genetic/genetics ; Tumor Suppressor Protein p53/*genetics/*metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressX. Xu ; S. Pan ; S. Cheng ; B. Zhang ; D. Mu ; P. Ni ; G. Zhang ; S. Yang ; R. Li ; J. Wang ; G. Orjeda ; F. Guzman ; M. Torres ; R. Lozano ; O. Ponce ; D. Martinez ; G. De la Cruz ; S. K. Chakrabarti ; V. U. Patil ; K. G. Skryabin ; B. B. Kuznetsov ; N. V. Ravin ; T. V. Kolganova ; A. V. Beletsky ; A. V. Mardanov ; A. Di Genova ; D. M. Bolser ; D. M. Martin ; G. Li ; Y. Yang ; H. Kuang ; Q. Hu ; X. Xiong ; G. J. Bishop ; B. Sagredo ; N. Mejia ; W. Zagorski ; R. Gromadka ; J. Gawor ; P. Szczesny ; S. Huang ; Z. Zhang ; C. Liang ; J. He ; Y. Li ; Y. He ; J. Xu ; Y. Zhang ; B. Xie ; Y. Du ; D. Qu ; M. Bonierbale ; M. Ghislain ; R. Herrera Mdel ; G. Giuliano ; M. Pietrella ; G. Perrotta ; P. Facella ; K. O'Brien ; S. E. Feingold ; L. E. Barreiro ; G. A. Massa ; L. Diambra ; B. R. Whitty ; B. Vaillancourt ; H. Lin ; A. N. Massa ; M. Geoffroy ; S. Lundback ; D. DellaPenna ; C. R. Buell ; S. K. Sharma ; D. F. Marshall ; R. Waugh ; G. J. Bryan ; M. Destefanis ; I. Nagy ; D. Milbourne ; S. J. Thomson ; M. Fiers ; J. M. Jacobs ; K. L. Nielsen ; M. Sonderkaer ; M. Iovene ; G. A. Torres ; J. Jiang ; R. E. Veilleux ; C. W. Bachem ; J. de Boer ; T. Borm ; B. Kloosterman ; H. van Eck ; E. Datema ; B. Hekkert ; A. Goverse ; R. C. van Ham ; R. G. Visser
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Evolution, Molecular ; Gene Duplication ; Gene Expression Regulation, Plant ; Genes, Plant/genetics ; Genetic Variation ; Genome, Plant/*genetics ; *Genomics ; Haplotypes/genetics ; Heterozygote ; Homozygote ; Immunity, Innate ; Inbreeding ; Molecular Sequence Annotation ; Molecular Sequence Data ; Plant Diseases/genetics ; Ploidies ; Solanum tuberosum/*genetics/physiologyPublished by: -
3Latest Papers from Table of Contents or Articles in PressGomez, S., Garrido-Garcia, A., Garcia-Gerique, L., Lemos, I., Sunol, M., de Torres, C., Kulis, M., Perez-Jaume, S., Carcaboso, A. M., Luu, B., Kieran, M. W., Jabado, N., Kozlenkov, A., Dracheva, S., Ramaswamy, V., Hovestadt, V., Johann, P., Jones, D. T. W., Pfister, S. M., Morales La Madrid, A., Cruz, O., Taylor, M. D., Martin-Subero, J.-I., Mora, J., Lavarino, C.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-03-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Articles: DFG German National LicensesMaas, J. W. ; Hattox, S. E. ; Martin, D. M. ; Landis, D. H.
Oxford, UK : Blackwell Publishing Ltd
Published 1979Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract— A direct method for measuring the rate of dopamine (DA) synthesis and the DA metabolites by the brain of awake monkeys (Macaca arctoides) is described. The method utilizes a coupling of a measure of cerebral blood flow with the mass spectrometrically determined difference in the concentrations of the metabolite under study in plasma obtained from arterial and internal jugular bulb blood. For homovanillic acid (HVA) a consistent and highly significant veno-arterial (V-A) difference of 2.2 ± 0.4 ng/ml of plasma (P 〈 0.0005) was found. When this V-A difference was coupled with a measure of cerebral blood flow it was determined that, in the awake monkey, the average output of HVA by brain was 113.4 ± 19.1ng/100g brain min−1. There were large individual variations, however, between animals (range = 38-194 ng/100g brain min−1). In contrast to HVA, no consistent V-A difference for dihydroxyphenylacetic acid (DOPAC) was found; i.e. the concentrations of DOPAC in plasma obtained from arterial and internal jugular bulb venous blood were essentially identical. These data indicate that, in contrast to the rat, in this non-human primate HVA is the major metabolic product of brain DA. Since HVA is the major metabolite of DA, production of HVA under steady state conditions gives a measure of DA synthesis by whole brain; i.e. the rate of DA synthesis by whole brain in the awake monkey is 113.4 ± 19.1ng/100g brain min−1. It is suggested that this technique may be of value in both basic and applied types of studies.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1741-2005Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Theology and Religious StudiesType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1365-2842Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A machine designed to simulate the physical parameters of masticatory function was used to investigate the amount of wear produced on perspex plates opposing discs of porcelain which were glazed, unglazed or finished to varying stages of a polishing sequence recommended with a proprietary finishing kit. The perspex specimens were abraded, under water at 37 °C for a total of 800 000 contacts using a contact time of 0·2 s, a sliding distance of 15 mm and a constant load of 0·19 N/mm2. Assessments of the wear of the perspex were based upon depth measurements of the wear track recorded on surfometric tracings. Further measurements of the cross-sectional area of the wear track were made using an image analysing computer. The investigation confirmed that the best finish and least abrasive surface was produced by glazing of porcelain. The finish produced by intermediate components of the proprietary finishing kit did not reduce the abrasiveness of the porcelain surface. It was necessary to complete the polishing sequence with diamond paste to achieve a surface which approached the wear characteristics of glazed porcelain. It is recommended that any adjusted porcelain restoration should be re-glazed or subjected to a finishing sequence which is followed through to a final stage of polishing with a diamond paste.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0020-7047Topics: PhilosophyTheology and Religious StudiesNotes: Book ReviewsURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0020-7047Topics: PhilosophyTheology and Religious StudiesNotes: Book reviewsURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0020-7047Topics: PhilosophyTheology and Religious StudiesNotes: Book reviewsURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0020-7047Topics: PhilosophyTheology and Religious StudiesNotes: Book reviewsURL: -
11Articles: DFG German National LicensesHarlos, K. ; Martin, D. M. A. ; O'Brien, D. P. ; Jones, E. Y. ; Stuart, D. I. ; Polikarpov, I. ; Miller, A. ; Tuddenham, E. G. D. ; Boys, C. W. G.
[s.l.] : Nature Publishing Group
Published 1994Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Residues 1-219 of tissue factor (TF2i9) were expressed in Escherichia coli, purified and crystallized as described previously5. TF2i9 was fully functional in assays for soluble tissue-factor activity6 and bound to factor VII in ligand blots7. The structure of TF219 was solved by multiple ...Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0021-9541Keywords: Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyMedicineNotes: Insulin-like growth factor-II (IGF-II) is highly expressed in fetal tissues and may act as an autocrine growth factor during early embryogenesis. The SH-SY5Y human neuroblastoma cell line also expresses IGF-II and its receptors and responds to exogenous IGF-II with increased DNA synthesis, cell division, and neuritic outgrowth. For this study, we tested the hypothesis that IGF-II mediates autocrine growth of SH-SY5Y cells in serum-free media. SH-SY5Y cells plated at high densities proliferated in serum-free media, whereas sparsely plated cells did not. IGF-II mRNA levels increased within 24 hours of serum deprivation and were associated with increased immunoreactive IGF-II protein. Exogenous addition of IGF-II increased 3H-TdR incorporation and cell number in a dose- and time-dependent fashion. By nuclear labelling experiments using 5-Bromo-2′ deoxyuridine (BrdU), we detected a twofold higher percentage of S phase nuclei after a 24-hour incubation in IGF-II. Treatment of SH-SY5Y cells with anti-IGF-II antibodies in serum-free media inhibited cell proliferation, and this inhibition was partially overcome by the addition of increasing concentrations of IGF-II. Collectively, our results indicate that IGF-II mediates an autocrine growth mechanism in SH-SY5Y cells that is associated with increased IGF-II expression. © 1993 Wiley-Liss, Inc.Additional Material: 8 Ill.Type of Medium: Electronic ResourceURL: