Search Results - (Author, Cooperation:D. M. Clark)

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  1. 1
    Staff View
    Publication Date:
    2014-10-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    K. Howe ; M. D. Clark ; C. F. Torroja ; J. Torrance ; C. Berthelot ; M. Muffato ; J. E. Collins ; S. Humphray ; K. McLaren ; L. Matthews ; S. McLaren ; I. Sealy ; M. Caccamo ; C. Churcher ; C. Scott ; J. C. Barrett ; R. Koch ; G. J. Rauch ; S. White ; W. Chow ; B. Kilian ; L. T. Quintais ; J. A. Guerra-Assuncao ; Y. Zhou ; Y. Gu ; J. Yen ; J. H. Vogel ; T. Eyre ; S. Redmond ; R. Banerjee ; J. Chi ; B. Fu ; E. Langley ; S. F. Maguire ; G. K. Laird ; D. Lloyd ; E. Kenyon ; S. Donaldson ; H. Sehra ; J. Almeida-King ; J. Loveland ; S. Trevanion ; M. Jones ; M. Quail ; D. Willey ; A. Hunt ; J. Burton ; S. Sims ; K. McLay ; B. Plumb ; J. Davis ; C. Clee ; K. Oliver ; R. Clark ; C. Riddle ; D. Elliot ; G. Threadgold ; G. Harden ; D. Ware ; S. Begum ; B. Mortimore ; G. Kerry ; P. Heath ; B. Phillimore ; A. Tracey ; N. Corby ; M. Dunn ; C. Johnson ; J. Wood ; S. Clark ; S. Pelan ; G. Griffiths ; M. Smith ; R. Glithero ; P. Howden ; N. Barker ; C. Lloyd ; C. Stevens ; J. Harley ; K. Holt ; G. Panagiotidis ; J. Lovell ; H. Beasley ; C. Henderson ; D. Gordon ; K. Auger ; D. Wright ; J. Collins ; C. Raisen ; L. Dyer ; K. Leung ; L. Robertson ; K. Ambridge ; D. Leongamornlert ; S. McGuire ; R. Gilderthorp ; C. Griffiths ; D. Manthravadi ; S. Nichol ; G. Barker ; S. Whitehead ; M. Kay ; J. Brown ; C. Murnane ; E. Gray ; M. Humphries ; N. Sycamore ; D. Barker ; D. Saunders ; J. Wallis ; A. Babbage ; S. Hammond ; M. Mashreghi-Mohammadi ; L. Barr ; S. Martin ; P. Wray ; A. Ellington ; N. Matthews ; M. Ellwood ; R. Woodmansey ; G. Clark ; J. Cooper ; A. Tromans ; D. Grafham ; C. Skuce ; R. Pandian ; R. Andrews ; E. Harrison ; A. Kimberley ; J. Garnett ; N. Fosker ; R. Hall ; P. Garner ; D. Kelly ; C. Bird ; S. Palmer ; I. Gehring ; A. Berger ; C. M. Dooley ; Z. Ersan-Urun ; C. Eser ; H. Geiger ; M. Geisler ; L. Karotki ; A. Kirn ; J. Konantz ; M. Konantz ; M. Oberlander ; S. Rudolph-Geiger ; M. Teucke ; C. Lanz ; G. Raddatz ; K. Osoegawa ; B. Zhu ; A. Rapp ; S. Widaa ; C. Langford ; F. Yang ; S. C. Schuster ; N. P. Carter ; J. Harrow ; Z. Ning ; J. Herrero ; S. M. Searle ; A. Enright ; R. Geisler ; R. H. Plasterk ; C. Lee ; M. Westerfield ; P. J. de Jong ; L. I. Zon ; J. H. Postlethwait ; C. Nusslein-Volhard ; T. J. Hubbard ; H. Roest Crollius ; J. Rogers ; D. L. Stemple
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-04-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Chromosomes/genetics ; Conserved Sequence/*genetics ; Evolution, Molecular ; Female ; Genes/genetics ; Genome/*genetics ; Genome, Human/genetics ; Genomics ; Humans ; Male ; Meiosis/genetics ; Molecular Sequence Annotation ; Pseudogenes/genetics ; Reference Standards ; Sex Determination Processes/genetics ; Zebrafish/*genetics ; Zebrafish Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Robinson, H. P. ; Adam, A. H. ; Fleming, J. E. E. ; Houston, Anne ; Clark, D. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1978
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Measurements of fetal cardiac electromechanical intervals were obtained in two groups of patients before and during labour. This was achieved by means of a system, developed in our Department, which allows the simultaneous recording of the fetal electrocardiogram and filtered Doppler signals from the fetal heart. The intervals studied were the pre-ejection period (PEP), the phase of isovolumetric contraction (IVC) and the left ventricular ejection time (LVET). Mean and SD values prior to the onset of labour were established and found to be 73.6±4.7 mseconds, 38.9±5.8 mseconds, and 155.2±9.6 mseconds respectively. While LVET varied inversely with heart rate, PEP and IVC showed no such correlation. In the second part of the study, serial measurements were made throughout labour in 22 patients. Eighteen of these fetuses had normal pH values at or near delivery, and in 16 of them PEP measurements varied by less than 10 mseconds from the pre-labour value, the remaining two fetuses exhibiting an unexplained shortening of this interval. All four fetuses with evidence of acidosis at delivery had PEP measurements which lengthened by more than 10 mseconds during labour. It is suggested that, with further development and experience, this technique may prove to be a useful adjunct to current methods for intrapartum fetal monitoring.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.1978.tb10476.x

    Articles: DFG German National Licenses
  4. 4
    Clark, D. M. ; Davey, B. A.
    Springer
    Published 1996
    Staff View
    ISSN:
    1420-8911
    Keywords:
    08C05 ; 08C15 ; 18A40 ; Duality theory ; injective ; natural duality ; strong duality ; congruence distributivity ; near unanimity
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract Building on the most current work in the theory of natural dualities, we continue the study of strong dualities for the quasi-variety generated by a finite algebra. We investigate ten different versions of what we would like to mean by a ‘good duality’. Each version concerns, among other things, a specific restriction on the type of the structures in the dual category which insures that the dual structures will in a useful sense be simple. Through each investigation we seek a theorem characterizing, in terms of finitely verifiable conditions, those finite algebras generating a quasi-variety which admits a strong duality meeting the given restrictions. Our study includes a careful treatment of coproducts, logarithmic dualities and strong dualities by various unary structures.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01195501

    Articles: DFG German National Licenses
  5. 5
    Clark, D. M. ; Moss, S. E. ; Wright, N. A. ; Crumpton, M. J.
    Springer
    Published 1991
    Staff View
    ISSN:
    1432-119X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract This paper describes the tissue distribution of annexin VI, a Ca2+-dependent phospholipid binding protein, and a member of the annexin super-gene family. In order to determine whether annexin VI expression correlated with a particular functional phenotype, an extensive series of non-pathological human tissues were examined, in which annexin VI was detected either immunohistochemically or by immunofluorescence, using a rabbit polyclonal anti-(human annexin VI)-IgG of known specificity. Although most tissues investigated were found to express annexin VI, the protein was usually confined to highly specific cell types within each tissue, the staining generally appearing cytoplasmic and diffuse. There was particularly good correlation between annexin VI expression and hormone secreting cells, with positive staining in the islet cells of the pancreas, the Leydig cells of the testis and the cells of the adrenal cortex. A notable exception was the parathyroid gland, which lacked detectable annexin VI. Although the protein was absent in most epithelia, it was expressed strongly in certain secretory epithelia; e.g. the ductal epithelial cells of the salivary glands and non-lactating breast, and the sweat glands and their ducts. The observation that the epithelial cells of lactating breast failed to stain for annexin VI suggests functional regulation of protein expression in this tissue. However, the most interesting finding was that annexin VI expression appeared to be developmentally regulated in B- and T-lymphocyte differentation, with negative staining in the proliferating B cells of the germinal centre of the lymph nodes, but strong staining in the mature small lymphocytes of the cortex, mantle zone and paracortex.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00315998

    Articles: DFG German National Licenses
  6. 6
    Clark, D. M. ; Wyatt, D. G.
    Springer
    Published 1969
    Staff View
    ISSN:
    1741-0444
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Description / Table of Contents:
    Sommaire L'article dćrit un nouveau débitmètre dont on compare les performances sur le plan de la sensibilité, de la puissance, et du volume à celles des autres modèles de débitmètres à bracelets.
    Abstract:
    Zusammenfassung Eine neues Flowmeter wird beschrieben und in seiner Leistung hinsichtlich Empfindlichkeit, Stromversorgung und Umfang mit anderen Manschettenflowmetern verglichen.
    Notes:
    Abstract An improved flowmeter is described and its performance compared, on the basis of sensitivity, power and bulk, with other designs of cuff flowmeter.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02474174

    Articles: DFG German National Licenses