Search Results - (Author, Cooperation:D. J. Liu)
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1Latest Papers from Table of Contents or Articles in PressWang, X., Daigger, G., Lee, D.-J., Liu, J., Ren, N.-Q., Qu, J., Liu, G., Butler, D.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-02Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
2Latest Papers from Table of Contents or Articles in PressP. Zanoni ; S. A. Khetarpal ; D. B. Larach ; W. F. Hancock-Cerutti ; J. S. Millar ; M. Cuchel ; S. DerOhannessian ; A. Kontush ; P. Surendran ; D. Saleheen ; S. Trompet ; J. W. Jukema ; A. De Craen ; P. Deloukas ; N. Sattar ; I. Ford ; C. Packard ; A. Majumder ; D. S. Alam ; E. Di Angelantonio ; G. Abecasis ; R. Chowdhury ; J. Erdmann ; B. G. Nordestgaard ; S. F. Nielsen ; A. Tybjaerg-Hansen ; R. F. Schmidt ; K. Kuulasmaa ; D. J. Liu ; M. Perola ; S. Blankenberg ; V. Salomaa ; S. Mannisto ; P. Amouyel ; D. Arveiler ; J. Ferrieres ; M. Muller-Nurasyid ; M. Ferrario ; F. Kee ; C. J. Willer ; N. Samani ; H. Schunkert ; A. S. Butterworth ; J. M. Howson ; G. M. Peloso ; N. O. Stitziel ; J. Danesh ; S. Kathiresan ; D. J. Rader
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Aged ; Amino Acid Substitution ; Animals ; Cholesterol, HDL/*blood ; Coronary Disease/*blood/*genetics ; DNA Mutational Analysis ; Female ; Genetic Variation ; Heterozygote ; Homozygote ; Humans ; Leucine/genetics ; Male ; Mice ; Middle Aged ; Proline/genetics ; Protein Processing, Post-Translational ; Risk ; Scavenger Receptors, Class B/*genetics/metabolismPublished by: -
3Latest Papers from Table of Contents or Articles in PressChong, L., Wen, J., Kubal, J., Sen, F. G., Zou, J., Greeley, J., Chan, M., Barkholtz, H., Ding, W., Liu, D.-J.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-12-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Chemistry, Materials SciencePublished by: -
4Articles: DFG German National LicensesCromwell, E. F. ; Liu, D.-J. ; Vrakking, M. J. J. ; Kung, A. H. ; Lee, Y. T.
College Park, Md. : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: A comprehensive study of the dynamics of H2 elimination from 1,4 and 1,3 cyclohexadiene is reported. Rotational and vibrational quantum state distributions as well as translation energy distributions for the H2 product are measured. State specific detection of H2 is accomplished with a transform limited vacuum ultraviolet–extreme ultraviolet laser system via (1+1) resonance enhanced multiphoton ionization (REMPI). Rate constants for the H2 elimination and 1,4 to 1,3 isomerization reactions are derived. A (v,J) correlation for H2 with v(parallel)J primarily is observed from anisotropy in the Doppler profiles. A clear picture of the transition state configuration of 1,4 cyclohexadiene is provided from the information obtained.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesZhao, M. F. ; Li, X. H. ; Yang, J. B. ; Xu, C. G. ; Hu, R. Y. ; Liu, D. J. ; Zhang, Q.
Oxford, UK : Blackwell Publishing Ltd
Published 1999Staff ViewISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The objective of this study was to investigate the relationship between molecular marker diversity and heterosis in both intra-and inter-sub-specific hybrids of rice to evaluate the feasibility of predicting hybrid performance using molecular markers. Eleven elite lines were intermated resulting in a diallel set including 10 indica × indica, 15 japonica × japonica and 30 indica × japonica crosses. The F1 hybrids and parents were evaluated for agronomic performance in a replicated field trial. The parental lines were tested for DNA polymorphisms with 113 restriction fragment length polymorphism (RFLP) probes covering the 12 rice chromosomes. Inter-subspecific crosses showed better performance and higher heterosis than intrasubspecific hybrids. Correlations of marker heterozygosity with hybrid performance and heterosis differed considerably between the two subspecies; they were higher in crosses within japonica subspecies than within indica subspecies. Very little correlation was detected in intersubspecific crosses. It was concluded that relationships between marker heterozygosity and hybrid performance were complex owing to germplasm diversity and the complexity of the genetic basis of heterosis. The implications of the results in predicting hybrid performance using molecular markers are discussed.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Barley was steeped, malted, and kilned under laboratory conditions. Surface structures of sections were examined by scanning electron microscopy and mineral element components were measured by X-ray microanalysis. Cell walls and grains of aleurone cells increased in size as a result of steeping and their structures changed throughout the subsequent malting process. In the center of the starchy endosperm, there was an extensive breakdown of the protein matrix, degradation of cell walls, and little degradation of large starch granules. Concentrations of most minerals were lower in steeped than in unsteeped barley, and continued to decrease throughout the malting process. Whereas mineral concentration changes in the husks and pericarp were minor, large decreases were noted in the aleurone tissues. Movements of mineral elements from aleurone grains to the starchy endosperm were slower for Ca and Mg than for P and K.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0022-2852Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0022-2852Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0039-9140Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0039-9140Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0022-2852Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesLi, W. L. ; Faris, J. D. ; Chittoor, J. M. ; Leach, J. E. ; Hulbert, S. H. ; Liu, D. J. ; Chen, P. D. ; Gill, B. S.
Springer
Published 1999Staff ViewISSN: 1432-2242Keywords: Key words Molecular mapping ; Wheat ; Resistance ; Defense response genesSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Defense response (DR) genes are a broad class involved in plant defense. In this study we mapped 36 probes representing seven classes of defense response genes. This collection of probes represents genes involved in the hypersensitive response (HR), pathogenesis-related (PR) genes, genes for the flavonoid metabolic pathway, genes encoding proline/glycine-rich proteins, ion channel regulators, lipoxygenase, lectin, and others. Using nullisomic-tetrasomic lines of ‘Chinese Spring’, we were able to assign at least 167 loci to the 21 chromosomes of wheat. Homoeologous group 7 chromosomes possessed the most DR loci followed by group 2. Sixty-two loci were placed on existing genetic linkage maps of wheat. Map locations indicated that the DR gene loci are not randomly distributed throughout the wheat genome, but rather are located in clusters and/or in distal gene-rich regions of the chromosomes. Knowledge of the chromosomal locations and genome organization of DR genes will be useful for candidate gene analysis of quantitative trait loci.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesQi, L. L. ; Wang, S. L. ; Chen, P. D. ; Liu, D. J. ; Friebe, B. ; Gill, B. S.
Springer
Published 1997Staff ViewISSN: 1432-2242Keywords: Key words Triticum aestivum ; Leymus racemosus ; Chromosome addition lines ; C-banding ; RLFP analysis ; HomoeologySource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Five disomic, two double-disomic, and two ditelosomic addition lines and one disomic substitution line derived from the crosses of Triticum aestivum (2n=6x=42, AABBDD)×Leymus racemosus (2n= 4x=28, JJNN) were identified by C-banding analysis. The homoeology of the added Leymus chromosomes was determined by RFLP analysis. Four of five disomic addition lines belonged to group 2, 5, 6 and 7 chromosomes of L. racemosus; these were designated as 2Lr?1(NAU516), 5Lr?1(NAU504, NAU514), 6Lr?1 (NAU512), and 7Lr?1(NAU501). Two additional chromosomes, 1Lr?1 and 3Lr?1, were present in double-disomic addition lines 1Lr?1+5Lr?1 (NAU525) and 3Lr?1+7Lr?1(NAU524), respec-tively. In the disomic substitution line wheat chromosome 2B was replaced by L. racemosus chromosome 2Lr?1 (NAU551). Two telocentric chromosomes, 2Lr?2S (NAU509) and 7Lr?1S (NAU511), were isolated as ditelosomic addition lines. The study presented here provides the first evidence of homoeology of the added L. racemosus chromosomes with wheat chromosomes using DNA markers. Our data provide the basis for further directed chromosome engineering aimed at producing compensating wheat-L. racemosus translocation lines.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesChen, W. P. ; Chen, P. D. ; Liu, D. J. ; Kynast, R. ; Friebe, B. ; Velazhahan, R. ; Muthukrishnan, S. ; Gill, B. S.
Springer
Published 1999Staff ViewISSN: 1432-2242Keywords: Key words Triticum aestivum ; Genetic transformation ; Thaumatin-like protein ; Wheat scab ; Fluorescent in situ hybridizationSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The possibility of controlling wheat scab (caused by Fusarium graminearum Schw.) was explored by engineering wheat plants for constitutive expression of pathogenesis-related (PR) protein genes. A rice thaumatin-like protein (TLP) gene (tlp) and a rice chitinase gene (chi11) were introduced into the spring wheat cultivar ’Bobwhite’ by co-transformation of the plasmids pGL2ubi-tlp (ubiquitin/tlp//CaMV 35S/hpt) and pAHG11 (CaMV 35S/chi11//ubiquitin/bar). The transformation was by biolistic bombardment. Bialaphos was used as the selection reagent. The integration and expression of the tlp, bar, chi11 and hpt genes were analyzed by Southern, Northern and Western blot analyses. The four transgenes co-segregated in the T1 progeny of the transgenic plant and were localized at the telomeric region of the chromosome 6A long arm by sequential N-banding and fluorescent in situ hybridization (FISH) using pAHG11 or pGL2ubi-tlp as the probes. Only the transgenes tlp and bar, under the control of the ubiquitin promoter-intron, were expressed. No expression of the chi11 and hpt genes, controlled by the CaMV 35S promoter, was detected in T1 plants. After inoculation with conidia of F. graminearum, the symptoms of scab developed significantly slower in transgenic plants of the T1, T2 and T3 generations expressing the tlp gene than in non-transformed control plants. This is the first report of enhanced resistance to F. graminearum in transgenic wheat plants with constitutive expression of TLP.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Haynaldia villosa ; Repeated sequence ; In situ hybridization ; Gene transferSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract A species-specific repeated sequence, pHvNAU62, was cloned from Haynaldia villosa, a wheat relative of great importance. It strongly hybridized to H. villosa, but not to wheat. In situ hybridization localized this sequence to six of seven H. villosa chromosome pairs in telomeric or sub-telomeric regions. Southern hybridization to whea-H. villosa addition lines showed that chromosomes 1V through 6V gave strong signals in ladders while chromosome 7V escaped detection. In addition to H. villosa, several Triticeae species were identified for a high abundance of the pHvNAU62 repeated sequence, among which Thinopyrum bassarabicum and Leymus racemosus produced the strongest signals. Sequence analysis indicated that the cloned fragment was 292 bp long, being AT rich (61%), and showed 67% homology of pSc7235, a rye repeated sequence. Isochizomer analysis suggested that the present repeated sequence was heavily methylated at the cytosine of the CpG dimer in the genome of H. villosa.It was also demonstrated that pHvNAU62 is useful in tagging the introduced 6VS chromosome arm, which confers a resistance gene to wheat powdery mildew, in the segregating generations.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Wheat ; Haynaldia villosa ; Alien translocation ; Powdery mildew resistance ; In situ hybridizationSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Several Triticum aestivum L.-Haynaldia villosa disomic 6VS/6AL translocation lines with powdery mildew resistance were developed from the hybridization between common wheat cultivar Yangmai 5 and alien substitution line 6V(6A). Mitotic and meiotic C-banding analysis, aneuploid analysis with double ditelosomic stocks, in situ hybridization, as well as the phenotypic assessment of powdery mildew resistance, were used to characterize these lines. The same translocated chromosome, with breakpoints near the centromere, appears to be present in all the lines, despite variation among the lines in their morphology and agronomic characteristics. The resistance gene, conferred by H. villosa and designated as Pm21, is a new and promising source of powdery mildew resistance in wheat breeding.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Key words Wheat ; Quantitative trait loci ; Candidate gene ; Disease resistance ; Molecular mappingSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Knowledge of the biological significance underlying quantitative trait loci (QTLs) for disease resistance is generally limited. In recent years, advances in plant-microbe interactions and genome mapping have lead to an increased understanding of the genes involved in plant defense and quantitative disease resistance. Here, we report on the application of the candidate-gene approach to the mapping of QTLs for disease resistance in a population of wheat recombinant inbreds. Over 50 loci, representing several classes of defense response (DR) genes, were placed on an existing linkage map and the genome was surveyed for QTLs associated with resistance to several diseases including tan spot, leaf rust, Karnal bunt, and stem rust. Analysis revealed QTLs with large effects in regions of putative resistance (R) genes, as previously reported. Several candidate genes, including oxalate oxidase, peroxidase, superoxide dismutase, chitinase and thaumatin, mapped within previously identified resistance QTLs and explained a greater amount of the phenotypic variation. A cluster of closely linked DR genes on the long arm of chromosome 7B, which included genes for catalase, chitinase, thaumatins and an ion channel regulator, had major effects for resistance to leaf rust of adult plants under conditions of natural infestation. The results of this study indicate that many minor resistance QTLs may be from the action of DR genes, and that the candidate-gene approach can be an efficient method of QTL identification.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Key words T. aestivum ; H. villosa ; C-banding ; RFLP ; Deletion mapping ; Pm21Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Three deletion lines (del6V?2S-1, del6V? 2L-1, and del6V?2L-2) of Haynaldia villosa chromosome 6V added to wheat were identified by C-banding and characterized by RFLP analyses. The breakpoints were located at fraction lengths (FL) 0.58 in del6V?2S-1 in the short arm, and FL 0.66 in del6V?2L-1 and FL 0.64 in del6V?2L-2 in the long arm. Thirty-one Triticeae homoeologous group-6 DNA probes were used to map RFLP loci in the deletion lines and the wheat-H. villosa disomic substitution (DS) line 6V?2(6A). Nine probes failed to detect polymorphism between Chinese Spring and DS6V?2(6A). Ten of sixteen polymorphic short-arm loci were not detected in del6V?2S-1. Thus, the loci are located in the deleted distal chromosome region. Six RFLP markers were mapped in the proximal 58% of 6VS. Of 20 DNA markers specific for 6VL, six mapped in the distal 36% of the long arm, and nine mapped in the proximal 64% of 6VL. The breakpoint of the short arm of 6V?2 occurs between Xpsr106 and Xcdo270, and that of the long arm between Xpsr915 and Xmwg934. The powdery mildew resistance gene Pm21 is located on the short arm of chromosome 6V?2. Pm21 is present in del6V?2S-1, and can be further mapped in the proximal 58% of 6V?2S.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesChen, W. P. ; Gu, X. ; Liang, G. H. ; Muthukrishnan, S. ; Chen, P. D. ; Liu, D. J. ; Gill, B. S.
Springer
Published 1998Staff ViewISSN: 1432-2242Keywords: Key wordsTriticum aestivum ; Transformation ; Microprojectile bombardment ; Chitinase gene ; bar geneSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Our long-term goal is to control wheat diseases through the enhancement of host plant resistance. The constitutive expression of plant defense genes to control fungal diseases can be engineered by genetic transformation. Our experimental strategy was to biolistically transform wheat with a vector DNA containing a rice chitinase gene under the control of the CaMV 35 S promoter and the bar gene under control of the ubiquitin promoter as a selectable marker. Immature embryos of wheat cv ‘Bobwhite’ were bombarded with plasmid pAHG11 containing the rice chitinase gene chi11 and the bar gene. The embryos were subcultured on MS2 medium containing the herbicide bialaphos. Calli were then transferred to a regeneration medium, also containing bialaphos. Seventeen herbicide-resistant putative transformants (T0) were selected after spraying with 0.2% Liberty, of which 16 showed bar gene expression as determined by the phosphinothricin acetyltransferase (PAT) assay. Of the 17 plants, 12 showed the expected 35-kDa rice chitinase as revealed by Western blot analysis. The majority of transgenic plants were morphologically normal and self-fertile. The integration, inheritance and expression of the chi11 and bar genes were confirmed by Southern hybridization, PAT and Western blot analysis of T0 and T1 transgenic plants. Mendelian segregation of herbicide resistance was observed in some T1 progenies. Interestingly, a majority of the T1 progeny had very little or no chitinase expression even though the chitinase transgene was intact. Because PAT gene expression under control of the ubiquitin promoter was unaffected, we conclude that the CaMV 35 S promoter is selectively inactivated in T1 transgenic wheat plants.Type of Medium: Electronic ResourceURL: