Search Results - (Author, Cooperation:D. Goldfarb)
-
1Latest Papers from Table of Contents or Articles in PressF. X. Theillet ; A. Binolfi ; B. Bekei ; A. Martorana ; H. M. Rose ; M. Stuiver ; S. Verzini ; D. Lorenz ; M. van Rossum ; D. Goldfarb ; P. Selenko
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; Cell Line ; Cytoplasm/chemistry/metabolism ; Electron Spin Resonance Spectroscopy ; HeLa Cells ; Humans ; Intracellular Space/*chemistry/*metabolism ; Neurons/cytology/metabolism ; Nuclear Magnetic Resonance, Biomolecular ; Protein Conformation ; alpha-Synuclein/*chemistry/*metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressChauche, C., Nogales, A., Zhu, H., Goldfarb, D., Ahmad Shanizza, A. I., Gu, Q., Parrish, C. R., Martinez-Sobrido, L., Marshall, J. F., Murcia, P. R.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-02-14Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
3Articles: DFG German National LicensesShane, J. J. ; Gromov, I. ; Vega, S. ; Goldfarb, D.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: A versatile high power X-band (8.5–9.5 GHz) pulsed EPR/ENDOR (electron-nuclear double resonance) spectrometer which can generate hundreds of microwave (MW) and rf pulses is described. The pulse programmer is constructed from a word generator with 32 channels and 4 ns resolution, coupled to five digital delay generators which can produce a total of ten pulses with a resolution better than 1 ns. The spectrometer contains two MW and two rf channels that allow independent variation of the frequency, amplitude, and phase of the MW and rf pulses. The ENDOR probe head is based on a bridged loop gap (BLG) resonator, coupling is achieved via a coupling loop connected to a waveguide, and the rf coil serves as a MW shield as well. The adjustment of the coupling is done by an up/down motion of the of the resonator assembly with respect to the fixed coupling loop. A flexible and user friendly data acquisition program written in C++ (Borland version 4.5), which uses the Windows-95 Multiple Document Interface (MDI) programming model, was developed to run the spectrometer. This program allows easy programming of any pulse sequence with sophisticated phase cycling. The performance of the spectrometer is demonstrated by two experiments. The first is the triple resonance hyperfine-selective (HS) ENDOR experiment carried out on a frozen solution of the copper protein laccase. The second is the two-dimensional hyperfine-ENDOR (HYEND) correlation experiment performed on a single crystal of γ-irradiated malonic acid. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesGoldfarb, D. ; Lifshitz, E. ; Zimmermann, H. ; Luz, Z.
College Park, Md. : American Institute of Physics (AIP)
Published 1985Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Deuterium NMR spectra are reported for several specifically deuterated hexaalkanoyloxytriphenylenes in their corresponding liquid crystalline phases. The higher homologs of this series are polymorphic and exhibit a variety of discotic mesophases, including both biaxial (D0 and D1) and uniaxial (D2) columnar phases. The ordering characteristics of these phases are studied using the quadrupolar splittings of the aromatic and aliphatic deuterons. The results show that during the transition from the biaxial D1 to the axial D2 phase the major susceptibility tensor switch orientation, apparently due to strong tilting of the molecules with respect to the columnar axis in the biaxial phase. Characteristic features which appear in the spectra of these phases are interpreted in terms of intercolumnar jumps of mesogen molecules.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesGOLDFARB, D. M. ; ZUEV, V. A. ; GERSHANOVITCH, V. N.
[s.l.] : Nature Publishing Group
Published 1964Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] This incompleteness of sphseroplasts is determined by the disturbance of the synthetic processes of intact cells1-8, which are probably connected with the increased permeability of 'ghost' sphaeroplasts4. However, it is not clear which structures of the phage membranes provoke the disturbance of ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The full metabolic value of protoplasts allowed them to be used as a system for the study of the reproduction of phages. In the work reported here, spheroplasts of E. coli B, obtained by means of treatment with ghosts of phage T4r, were examined. The 'ghosts' were obtained by means of Harriott's ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0962-8924Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0022-2364Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Keywords: Simplex Method ; Linear Programming ; Steepest-edge ; LU FactorizationSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract It is shown that suitable recurrences may be used in order to implement in practice the steepest-edge simplex linear programming algorithm. In this algorithm each iteration is along an edge of the polytope of feasible solutions on which the objective function decreases most rapidly with respect to distance in the space of all the variables. Results of computer comparisons on medium-scale problems indicate that the resulting algorithm requires less iterations but about the same overall time as the algorithm of Harris [8], which may be regarded as approximating the steepest-edge algorithm. Both show a worthwhile advantage over the standard algorithm.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Keywords: Convex quadratic programming ; interior point method ; Karmarkar's method ; logarithmic barrier function methodSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract We present a primal interior point method for convex quadratic programming which is based upon a logarithmic barrier function approach. This approach generates a sequence of problems, each of which is approximately solved by taking a single Newton step. It is shown that the method requires $$O(\sqrt n L)$$ iterations and O(n 3.5 L) arithmetic operations. By using modified Newton steps the number of arithmetic operations required by the algorithm can be reduced to O(n 3 L).Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Source: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0162-0134Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0022-2364Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0022-2364Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Keywords: Linear programming ; Basis matrix ; LU factorization ; PricingSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract Many implementations of the simplex method require the row of the inverse of the basis matrixB corresponding to the pivot row at each iteration for updating either a pricing vector or the nonbasic reduced costs. In this note we show that if the Bartels—Golub algorithm [1, 2] or one of its variants is used to update theLU factorization ofB, then less computing is needed if one works with the factors of the updatedB than with those ofB. These results are discussed as they apply to the column selection algorithms recently proposed by Goldfarb and Reid [4, 5] and Harris [6].Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Keywords: Conjugate directions ; Variable metric ; Quasi-Newton ; Optimization ; Cholesky factorization ; Orthogonal vectors ; SparsitySource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract It is shown how to generate conjugate directions without exact line searches by applying variable metric updating formulas in factorized form to give the columns of the Cholesky factors of the Hessian matrix one at a time. Minimization methods based upon these results are given, including one which can take advantage of sparsity in the matrix of second derivatives of the objective function. The results of some numerical tests on a small sample of test problems are presented.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1436-4646Keywords: Assignment Problem ; Dual Simplex Method ; Weighted Matching ; Optimization ; Sparsity ; Block PivotSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract Efficient algorithms based upon Balinski's signature method are described for solving then × n assignment problem. These algorithms are special variants of the dual simplex method and are shown to have computational bounds of O(n 3). Variants for solving sparse assignment problems withm arcs that require O(m) space and O(mn + n 2 logn) time in the worst case are also presented.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1433-8726Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Despite improved immunosuppression and early allograft survival, long-term survival of allografts remains unchanged. Late renal allograft loss has traditionally been considered to result from repeated or unresolved episodes of acute rejection that lead to chronic immune-mediated allograft rejection. However, late renal allograft loss is known to occur in the absence of prior episodes of acute rejection. It is therefore proposed that factors other than histocompatibility influence long-term allograft survival. Evidence for nonimmunologic factors contributing to late allograft loss is presented. The central hypothesis is that following renal allograft mass reduction (from any etiology), glomerular hyperperfusion and hyperfiltration develop and lead to progressive renal dysfunction, proteinuria, histopathologic allograft changes, and late allograft failure. Multiple nonimmunologic factors that could contribute to reduced renal mass and ultimately promote chronic allograft loss as a result of hyperfiltration nephropathy are presented along with possible therapeutic strategies for the prevention and treatment of glomerular hyperfiltration.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesGoldfarb, D. M. ; Goldberg, G. I. ; Chernin, L. S. ; Gukova, L. A. ; Avdienko, I. D. ; Kuznetsova, B. N. ; Kushner, I. Ch.
Springer
Published 1973Staff ViewISSN: 1617-4623Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary A protein present in filtrates of E. coli K-12 male strains is responsible for their ability to increase the yield of recombinants in conjugation and to inhibit nitrogen mustard after-effect (NMAE) in F - cells. The protein, designated “recombination-stimulating factor” (RSF), was purified 200–300 times from HfrC filtrate. Two Rsf- mutants of strain HfrC were isolated which fail to produce RSF; these mutations affect an episomal gene. RSF action involves the attachment of RSF to the F - cell surface and requires the integrity of the RSF-cell complex. Some step of recombination after the transfer of the donor chromosomal fragment into the recipient is affected by RSF.Type of Medium: Electronic ResourceURL: