Search Results - (Author, Cooperation:D. G. Crowley)
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1W. Xue ; S. Chen ; H. Yin ; T. Tammela ; T. Papagiannakopoulos ; N. S. Joshi ; W. Cai ; G. Yang ; R. Bronson ; D. G. Crowley ; F. Zhang ; D. G. Anderson ; P. A. Sharp ; T. Jacks
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Base Sequence ; *CRISPR-Cas Systems ; Cell Transformation, Neoplastic/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Female ; *Genes, Tumor Suppressor ; Genes, p53/genetics ; Genetic Engineering/*methods ; Hepatocytes/metabolism/pathology ; Lipid Metabolism ; Liver/cytology/*metabolism/pathology ; Liver Neoplasms/genetics/metabolism/pathology ; Mice ; Molecular Sequence Data ; Mutagenesis/*genetics ; Mutation/*genetics ; Oncogenes/*genetics ; PTEN Phosphohydrolase/genetics ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; beta Catenin/geneticsPublished by: -
2Crowley, D. G. ; Frank, F. C. ; Mackley, M. R. ; Stephenson, R. G.
New York : Wiley-Blackwell
Published 1976Staff ViewISSN: 0098-1273Keywords: Physics ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyPhysicsNotes: We report flow birefringence observations of polyethylene oxide solutions in a four roll mill where the flow field in the central region of the mill approximates well to that of pure shearing flow. When flow birefringence is observed it is seen to be highly localized within a region close to the “outgoing” asymptotic plane of flow. The phenomenon can be explained in terms of the flow birefringence corresponding to high extension of some polymer chains where the localization is caused by the chains requiring sufficient time in the flow field to become extended. This explanation has important consequences in all “persistently extensional flows” and can explain the origin of previously published results of localized flow birefringence observed for polyethylene solutions in axial compression and axial extensional flows.Additional Material: 8 Ill.Type of Medium: Electronic ResourceURL: