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1T. Lappalainen ; M. Sammeth ; M. R. Friedlander ; P. A. t Hoen ; J. Monlong ; M. A. Rivas ; M. Gonzalez-Porta ; N. Kurbatova ; T. Griebel ; P. G. Ferreira ; M. Barann ; T. Wieland ; L. Greger ; M. van Iterson ; J. Almlof ; P. Ribeca ; I. Pulyakhina ; D. Esser ; T. Giger ; A. Tikhonov ; M. Sultan ; G. Bertier ; D. G. MacArthur ; M. Lek ; E. Lizano ; H. P. Buermans ; I. Padioleau ; T. Schwarzmayr ; O. Karlberg ; H. Ongen ; H. Kilpinen ; S. Beltran ; M. Gut ; K. Kahlem ; V. Amstislavskiy ; O. Stegle ; M. Pirinen ; S. B. Montgomery ; P. Donnelly ; M. I. McCarthy ; P. Flicek ; T. M. Strom ; H. Lehrach ; S. Schreiber ; R. Sudbrak ; A. Carracedo ; S. E. Antonarakis ; R. Hasler ; A. C. Syvanen ; G. J. van Ommen ; A. Brazma ; T. Meitinger ; P. Rosenstiel ; R. Guigo ; I. G. Gut ; X. Estivill ; E. T. Dermitzakis
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-09-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Line, Transformed ; Exons/genetics ; Gene Expression Profiling ; Genetic Variation/*genetics ; Genome, Human/*genetics ; *High-Throughput Nucleotide Sequencing ; Humans ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; RNA, Messenger/analysis/genetics ; *Sequence Analysis, RNA ; Transcriptome/*geneticsPublished by: -
2Staff View
ISSN: 0009-8981Keywords: 6-Keto-PGF"1"α ; Acute uraemia ; Forestomach ; Gastric mucosa ; Gastric ulcer ; Prostaglandin E"2 ; RatSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 1434-4726Keywords: Oropharyngeal carcinoma ; Hypopharyngeal carcinoma ; Nucleolar organizer regions ; Lymphogenic metastasesSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary It is supposed that the nucleolar organizer regions (NORs), genes on which ribosomal RNA is coded, may contain information on the structure of the nucleolus and on nucleolar activity which permits discrimination between normal and neoplastic cells and their proliferation activity. In the present study, the histological sections of 144 patients with carcinomas of the oropharynx and hypopharynx were studied in a retrospective approach to determine the absolute NOR counts per 100 nuclei and investigate their influence on the prognosis and extent of lymphogenic formation of metastases. An absolute NOR count of 681 per 100 nuclei was found to give reliable discrimination between stage NO or N1 carcinomas and stage N2 or N3 disease.Type of Medium: Electronic ResourceURL: -
4Zhang, Z. ; Suchanek, E. ; Eßer, D. ; Lutz, H. D. ; Nikolova, D. ; Maneva-Petrova, M.
Weinheim : Wiley-Blackwell
Published 1996Staff ViewISSN: 0044-2313Keywords: Nickel orthoperiodate ; i.r., Raman spectra ; crystal structure ; Chemistry ; Inorganic ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: NiH3IO6 · 6 H2O - Crystal Structures and Vibrational SpectraThe crystal structure of NiH3IO6 · 6 H2O has been determined by X-ray single-crystal diffraction (Pc, Z = 2, a = 516.74(9), b = 981.5(2), c = 1052.5(2) pm, β = 116.496(8)°) on the basis of 4169 unique reflections (R = 1.96%). The structure is built up of distorted Ni(H2O)62+ and H3IO62- octahedra linked by hydrogen bonding. IR and Raman spectra of both the title compound and isostructural MgH3IO6 · 6 H2O as well as of deuterated specimens are given. There are up to 14 different OH(OD) modes in the spectra of isotopically dilute samples due to the 15 different hydrogen positions of the structure. The internal modes of the meridional H3IO62- ions (pseudo C2v symmetry) are discussed with respect to that double T-shaped entity, which gives rise to only two instead of 3I—O, I—O(H), and OH stretches in the IR and Raman spectra, i.e. the same as for facial (C3v) structured ions.Notes: Die Kristallstruktur (Pc, Z = 2) von NiH3IO6 · 6 H2O wurde mittels Röntgen-Einkristallmessungen auf der Basis von 4169 symmetrieunabhängigen Reflexen bestimmt (R = 1,96%). IR- und Raman-Spektren von NiH3IO6 · 6 H2O und der isotypen Verbindung MgH3IO6 · 6 H2O sowie von deuterierten Präparaten werden mitgeteilt. Die Spektren isotypenverdünnter Proben zeigen bis zu 14 OH(OD)-Streckschwingungen entsprechend den 15 verschiedenen Wasserstoff-Positionen der Struktur. Die meridionalen H3IO62--Ionen (Pseudosymmetrie C2v) besitzen wegen der T-förmigen Anordnung der je 3 IO-und IOH-Gruppen nur je 2 IO-, IO(H)- und OH-Streckschwingungen in den IR- und Raman-Spektren und können daher schwingungsspektroskopisch nicht von H3IO62--Ionen mit facialer Struktur (C3v) unterschieden werden.Additional Material: 8 Ill.Type of Medium: Electronic ResourceURL: