Search Results - (Author, Cooperation:D. E. Root)
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1Latest Papers from Table of Contents or Articles in PressJ. A. Losman ; R. E. Looper ; P. Koivunen ; S. Lee ; R. K. Schneider ; C. McMahon ; G. S. Cowley ; D. E. Root ; B. L. Ebert ; W. G. Kaelin, Jr.
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-02-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics/*metabolism ; Glutarates/*metabolism ; *Hematopoiesis ; Humans ; Isocitrate Dehydrogenase/genetics/*metabolism ; Leukemia/*enzymology/genetics ; Models, Biological ; Procollagen-Proline Dioxygenase/*antagonists & inhibitorsPublished by: -
2Latest Papers from Table of Contents or Articles in PressG. V. Kryukov ; F. H. Wilson ; J. R. Ruth ; J. Paulk ; A. Tsherniak ; S. E. Marlow ; F. Vazquez ; B. A. Weir ; M. E. Fitzgerald ; M. Tanaka ; C. M. Bielski ; J. M. Scott ; C. Dennis ; G. S. Cowley ; J. S. Boehm ; D. E. Root ; T. R. Golub ; C. B. Clish ; J. E. Bradner ; W. C. Hahn ; L. A. Garraway
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-02-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Deoxyadenosines/metabolism/pharmacology ; Enzyme Inhibitors/pharmacology ; Gene Deletion ; Humans ; Isoquinolines/pharmacology ; Neoplasms/*drug therapy/enzymology ; Protein-Arginine N-Methyltransferases/antagonists & ; inhibitors/genetics/*metabolism ; Purine-Nucleoside Phosphorylase/genetics/*metabolism ; Pyrimidines/pharmacology ; Thionucleosides/metabolism/pharmacology ; Transcription FactorsPublished by: -
3Latest Papers from Table of Contents or Articles in PressS. R. Floyd ; M. E. Pacold ; Q. Huang ; S. M. Clarke ; F. C. Lam ; I. G. Cannell ; B. D. Bryson ; J. Rameseder ; M. J. Lee ; E. J. Blake ; A. Fydrych ; R. Ho ; B. A. Greenberger ; G. C. Chen ; A. Maffa ; A. M. Del Rosario ; D. E. Root ; A. E. Carpenter ; W. C. Hahn ; D. M. Sabatini ; C. C. Chen ; F. M. White ; J. E. Bradner ; M. B. Yaffe
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-06-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; Adenosine Triphosphatases/metabolism ; Cell Cycle Checkpoints/radiation effects ; Cell Line, Tumor ; Cell Survival/radiation effects ; Chromatin/chemistry/*metabolism/radiation effects ; *Chromatin Assembly and Disassembly/radiation effects ; *DNA Damage ; DNA Repair/radiation effects ; DNA-Binding Proteins/metabolism ; Histones/chemistry/metabolism ; Humans ; Lysine/chemistry/metabolism ; Multiprotein Complexes/metabolism ; Nuclear Proteins/chemistry/deficiency/genetics/*metabolism ; Phosphorylation/radiation effects ; Positive Transcriptional Elongation Factor B/metabolism ; Protein Isoforms/metabolism ; Radiation, Ionizing ; *Signal Transduction/radiation effects ; Transcription Factors/chemistry/deficiency/genetics/*metabolismPublished by: -
4Latest Papers from Table of Contents or Articles in PressE. S. Egan ; R. H. Jiang ; M. A. Moechtar ; N. S. Barteneva ; M. P. Weekes ; L. V. Nobre ; S. P. Gygi ; J. A. Paulo ; C. Frantzreb ; Y. Tani ; J. Takahashi ; S. Watanabe ; J. Goldberg ; A. S. Paul ; C. Brugnara ; D. E. Root ; R. C. Wiegand ; J. G. Doench ; M. T. Duraisingh
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-05-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD44/genetics ; Antigens, CD55/*genetics ; Cell Differentiation/genetics ; Cells, Cultured ; Erythrocytes/cytology/metabolism/*parasitology ; Genetic Testing ; Hematopoietic Stem Cells/cytology ; Host-Parasite Interactions/*genetics ; Humans ; Malaria, Falciparum/*genetics/*parasitology ; Plasmodium falciparum/*pathogenicity ; RNA, Small Interfering/geneticsPublished by: -
5Latest Papers from Table of Contents or Articles in PressO. Shalem ; N. E. Sanjana ; E. Hartenian ; X. Shi ; D. A. Scott ; T. S. Mikkelsen ; D. Heckl ; B. L. Ebert ; D. E. Root ; J. G. Doench ; F. Zhang
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-12-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/genetics ; Caspase 9/*genetics ; Cell Survival/*genetics ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Cullin Proteins/genetics ; Drug Resistance, Neoplasm/*genetics ; Gene Knockout Techniques ; Gene Library ; Genes, Neurofibromatosis 1 ; Genes, Neurofibromatosis 2 ; Genetic Loci ; Genetic Testing/*methods ; Genome-Wide Association Study ; Humans ; Indoles/therapeutic use ; Lentivirus ; Mediator Complex/genetics ; Melanoma/drug therapy/*genetics ; Pluripotent Stem Cells/*metabolism ; Protein Kinase Inhibitors/therapeutic use ; Selection, Genetic ; Sulfonamides/therapeutic use ; Transcription Factors/genetics ; raf Kinases/antagonists & inhibitorsPublished by: -
6Latest Papers from Table of Contents or Articles in PressD. B. Wheeler ; R. Zoncu ; D. E. Root ; D. M. Sabatini ; C. L. Sawyers
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-09-05Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Line, Tumor ; Gene Deletion ; Humans ; Immunoprecipitation ; Lysosomal-Associated Membrane Protein 2/metabolism ; Multiprotein Complexes/metabolism ; Mutation ; Neoplasms/genetics/*metabolism/pathology ; Oncogene Proteins/genetics/*metabolism ; Phosphatidylinositol 3-Kinases/*metabolism ; Phosphorylation/genetics ; Protein Transport ; Protein-Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA Interference ; RNA, Small Interfering/genetics ; Receptor, Platelet-Derived Growth Factor alpha/metabolism ; TOR Serine-Threonine Kinases/metabolism ; rab GTP-Binding Proteins/genetics/*metabolismPublished by: -
7Latest Papers from Table of Contents or Articles in PressP. Zhou ; D. R. Shaffer ; D. A. Alvarez Arias ; Y. Nakazaki ; W. Pos ; A. J. Torres ; V. Cremasco ; S. K. Dougan ; G. S. Cowley ; K. Elpek ; J. Brogdon ; J. Lamb ; S. J. Turley ; H. L. Ploegh ; D. E. Root ; J. C. Love ; G. Dranoff ; N. Hacohen ; H. Cantor ; K. W. Wucherpfennig
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-01-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, Neoplasm/immunology ; Apoptosis/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/cytology/immunology/secretion ; Cell Proliferation ; Cytokines/immunology/secretion ; Female ; Gene Knockdown Techniques ; High-Throughput Nucleotide Sequencing ; *Immunotherapy/methods ; Lymphocytes, Tumor-Infiltrating/cytology/immunology/metabolism/secretion ; Melanoma, Experimental/immunology ; Mice ; Mice, Inbred C57BL ; *Molecular Targeted Therapy ; Protein Phosphatase 2/deficiency/genetics/*metabolism ; RNA, Small Interfering/genetics ; Reproducibility of Results ; Tumor Microenvironment/*immunologyPublished by: -
8Latest Papers from Table of Contents or Articles in PressM. Guttman ; J. Donaghey ; B. W. Carey ; M. Garber ; J. K. Grenier ; G. Munson ; G. Young ; A. B. Lucas ; R. Ach ; L. Bruhn ; X. Yang ; I. Amit ; A. Meissner ; A. Regev ; J. L. Rinn ; D. E. Root ; E. S. Lander
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-08-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Differentiation/*genetics ; Cell Lineage/genetics ; Chromatin/genetics/metabolism ; Gene Expression Regulation/genetics ; Gene Knockdown Techniques ; Mice ; Pluripotent Stem Cells/*cytology/*metabolism ; Protein Binding ; RNA, Untranslated/*genetics/*metabolism ; Transcription Factors/metabolismPublished by: -
9Latest Papers from Table of Contents or Articles in PressR. Possemato ; K. M. Marks ; Y. D. Shaul ; M. E. Pacold ; D. Kim ; K. Birsoy ; S. Sethumadhavan ; H. K. Woo ; H. G. Jang ; A. K. Jha ; W. W. Chen ; F. G. Barrett ; N. Stransky ; Z. Y. Tsun ; G. S. Cowley ; J. Barretina ; N. Y. Kalaany ; P. P. Hsu ; K. Ottina ; A. M. Chan ; B. Yuan ; L. A. Garraway ; D. E. Root ; M. Mino-Kenudson ; E. F. Brachtel ; E. M. Driggers ; D. M. Sabatini
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/enzymology/*genetics/*metabolism/pathology ; Cell Line, Tumor ; Cell Proliferation ; Citric Acid Cycle/physiology ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; *Genomics ; Glutamic Acid/metabolism ; Humans ; Ketoglutaric Acids/metabolism ; Melanoma/enzymology/genetics ; Mice ; Neoplasm Transplantation ; Phosphoglycerate Dehydrogenase/genetics/metabolism ; RNA Interference ; Serine/*biosynthesisPublished by: -
10Latest Papers from Table of Contents or Articles in PressC. M. Johannessen ; L. A. Johnson ; F. Piccioni ; A. Townes ; D. T. Frederick ; M. K. Donahue ; R. Narayan ; K. T. Flaherty ; J. A. Wargo ; D. E. Root ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Antineoplastic Agents/*pharmacology ; CREB-Binding Protein/metabolism ; Cell Line, Tumor ; Cell Lineage ; Cyclic AMP/metabolism ; Drug Resistance, Neoplasm/*genetics ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Melanocytes/cytology/*drug effects/enzymology ; Melanoma/enzymology/physiopathology ; Mitogen-Activated Protein Kinases/*metabolism ; Protein Kinase Inhibitors/*pharmacology ; Signal Transduction ; Transcription Factors/genetics/metabolismPublished by: