Search Results - (Author, Cooperation:D. E. Jennings)

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  1. 1
    S. A. Stern ; F. Bagenal ; K. Ennico ; G. R. Gladstone ; W. M. Grundy ; W. B. McKinnon ; J. M. Moore ; C. B. Olkin ; J. R. Spencer ; H. A. Weaver ; L. A. Young ; T. Andert ; J. Andrews ; M. Banks ; B. Bauer ; J. Bauman ; O. S. Barnouin ; P. Bedini ; K. Beisser ; R. A. Beyer ; S. Bhaskaran ; R. P. Binzel ; E. Birath ; M. Bird ; D. J. Bogan ; A. Bowman ; V. J. Bray ; M. Brozovic ; C. Bryan ; M. R. Buckley ; M. W. Buie ; B. J. Buratti ; S. S. Bushman ; A. Calloway ; B. Carcich ; A. F. Cheng ; S. Conard ; C. A. Conrad ; J. C. Cook ; D. P. Cruikshank ; O. S. Custodio ; C. M. Dalle Ore ; C. Deboy ; Z. J. Dischner ; P. Dumont ; A. M. Earle ; H. A. Elliott ; J. Ercol ; C. M. Ernst ; T. Finley ; S. H. Flanigan ; G. Fountain ; M. J. Freeze ; T. Greathouse ; J. L. Green ; Y. Guo ; M. Hahn ; D. P. Hamilton ; S. A. Hamilton ; J. Hanley ; A. Harch ; H. M. Hart ; C. B. Hersman ; A. Hill ; M. E. Hill ; D. P. Hinson ; M. E. Holdridge ; M. Horanyi ; A. D. Howard ; C. J. Howett ; C. Jackman ; R. A. Jacobson ; D. E. Jennings ; J. A. Kammer ; H. K. Kang ; D. E. Kaufmann ; P. Kollmann ; S. M. Krimigis ; D. Kusnierkiewicz ; T. R. Lauer ; J. E. Lee ; K. L. Lindstrom ; I. R. Linscott ; C. M. Lisse ; A. W. Lunsford ; V. A. Mallder ; N. Martin ; D. J. McComas ; R. L. McNutt, Jr. ; D. Mehoke ; T. Mehoke ; E. D. Melin ; M. Mutchler ; D. Nelson ; F. Nimmo ; J. I. Nunez ; A. Ocampo ; W. M. Owen ; M. Paetzold ; B. Page ; A. H. Parker ; J. W. Parker ; F. Pelletier ; J. Peterson ; N. Pinkine ; M. Piquette ; S. B. Porter ; S. Protopapa ; J. Redfern ; H. J. Reitsema ; D. C. Reuter ; J. H. Roberts ; S. J. Robbins ; G. Rogers ; D. Rose ; K. Runyon ; K. D. Retherford ; M. G. Ryschkewitsch ; P. Schenk ; E. Schindhelm ; B. Sepan ; M. R. Showalter ; K. N. Singer ; M. Soluri ; D. Stanbridge ; A. J. Steffl ; D. F. Strobel ; T. Stryk ; M. E. Summers ; J. R. Szalay ; M. Tapley ; A. Taylor ; H. Taylor ; H. B. Throop ; C. C. Tsang ; G. L. Tyler ; O. M. Umurhan ; A. J. Verbiscer ; M. H. Versteeg ; M. Vincent ; R. Webbert ; S. Weidner ; G. E. Weigle, 2nd ; O. L. White ; K. Whittenburg ; B. G. Williams ; K. Williams ; S. Williams ; W. W. Woods ; A. M. Zangari ; E. Zirnstein
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-10-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    H. A. Weaver ; M. W. Buie ; B. J. Buratti ; W. M. Grundy ; T. R. Lauer ; C. B. Olkin ; A. H. Parker ; S. B. Porter ; M. R. Showalter ; J. R. Spencer ; S. A. Stern ; A. J. Verbiscer ; W. B. McKinnon ; J. M. Moore ; S. J. Robbins ; P. Schenk ; K. N. Singer ; O. S. Barnouin ; A. F. Cheng ; C. M. Ernst ; C. M. Lisse ; D. E. Jennings ; A. W. Lunsford ; D. C. Reuter ; D. P. Hamilton ; D. E. Kaufmann ; K. Ennico ; L. A. Young ; R. A. Beyer ; R. P. Binzel ; V. J. Bray ; A. L. Chaikin ; J. C. Cook ; D. P. Cruikshank ; C. M. Dalle Ore ; A. M. Earle ; G. R. Gladstone ; C. J. Howett ; I. R. Linscott ; F. Nimmo ; J. W. Parker ; S. Philippe ; S. Protopapa ; H. J. Reitsema ; B. Schmitt ; T. Stryk ; M. E. Summers ; C. C. Tsang ; H. H. Throop ; O. L. White ; A. M. Zangari
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-03-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2016-03-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Jennings, D. E. ; Kuznetsov, Yu. A. ; Timoshenko, E. G. ; Dawson, K. A.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1998
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    We present a lattice model of amphiphile, solvent and polymer. The model is simulated in a hybrid Monte Carlo scheme using the grand canonical ensemble for solvent and amphiphile, and the canonical ensemble for the polymer. The model has been studied for a limited range of parameters, albeit consistent with the most elementary properties of surfactants and polymer. However, despite this apparently very simple set of microscopic interactions, a number of concentration-dependent effective interactions emerge, and cause conformational transitions of the polymer. We examine surfactant-polymer binding curves to relate these conformational changes of the polymer to binding. We have established the viability of using Monte Carlo simulations to study solutions of amphiphile, polymer and solvent. © 1998 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.475541

    Articles: DFG German National Licenses
  5. 5
    AVNER, D. L. ; DORSCH, E. R. ; JENNINGS, D. E. ; GRESKI-ROSE, P. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background: Lansoprazole is a new proton pump inhibitor for the treatment of peptic ulcer disease. Methods: A double-blind, multicentre study was undertaken in 2 9 6 patients with endoscopically proven duodenal ulcer to compare the efficacy and safety of lansoprazole 15, 30 or 60 mg with placebo. Ulcer healing was documented by endoscopy at 2 and 4 weeks; patients whose ulcers healed after 4 weeks were followed for up to 6 months post-treatment. Results: Four-week healing rates of 89.4% 91.7% and 89.9% were obtained with lansoprazole 15, 30 and 60 mg, respectively, compared with 46.1 % on placebo (P 〈 0.001). All three doses of lansoprazole produced rapid symptom relief, although patients taking 60 mg lansoprazole required fewer antacids than did those taking 15 mg. At 6 months, the percentages of patients healed were 45.3%, 40.0% and 38.4% in the lansoprazole 15, 30 and 60 mg dosage groups, respectively, and 2 5.3 % for the placebo group. No significant adverse events were documented during the period of this trial. Conclusion: Lansoprazole is an effective and safe treatment for duodenal ulcer and the 15 mg dose is as effective as 30 or 60 mg.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2036.1995.tb00415.x

    Articles: DFG German National Licenses
  6. 6
    Bell, N. ; Karol, M. D. ; Sachs, G. ; Greski-Rose, P. ; Jennings, D. E. ; Hunt, R. H.

    Oxford UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    A double-blind, placebo-controlled study to assess the duration of effect of lansoprazole 30 mg o.m. on intragastric pH, acid secretion, gastrin levels, the potential for rebound acidity, and the relationship between gastric acid and drug pharmacokinetic parameters.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:Sixteen subjects were treated with lansoprazole 30 mg daily or placebo for 14 days, followed by a 7-day post-dosing period and a post-study evaluation on day 28. Ambulatory 24-h pH was recorded and pentagastrin-stimulated acid secretion measured. Plasma kinetics of lansoprazole were determined.〈section xml:id="abs1-3"〉〈title type="main"〉Results:Mean intragastric pH in the lansoprazole group increased significantly (P 〈 0.05) from baseline to day 14 compared to placebo. After cessation of treatment, secretory activity, as measured by intragastric pH, basal acid output and stimulated acid output, returned to baseline in 2 to 4 days without any overshoot, indicating the absence of acid rebound. Lansoprazole’s terminal disposition half-life was 1.11 h. Mean pH and serum gastrin returned to baseline with half-lives of 22 and 19 h, respectively.〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions:Lansoprazole 30 mg daily significantly increases mean intragastric pH without producing acid rebound. Regeneration of acid production depends primarily on de novo synthesis of the acid pump.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2036.2001.00831.x

    Articles: DFG German National Licenses
  7. 7
    ROBINSON, M. ; SAHBA, B. ; AVNER, D. ; JHALA, N. ; GRESKI-ROSE, P. A. ; JENNINGS, D. E.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background: Lansoprazole is a new proton pump inhibitor which produces prolonged decrease of gastric acidity. The aim of this study was to compare lansoprazole to a standard dose of ranitidine in the treatment of patients with reflux oesophagitis. Methods: Two hundred and forty-seven patients with erosive oesophagitis were randomly assigned to 8 weeks of treatment with either 30 mg lansoprazole once daily or 150 mg ranitidine twice daily. Results: Two hundred and forty-two patients were included in the analysis. Lansoprazole (30 mg) daily, healed oesophagitis in 92.1% of patients after 8 weeks of treatment. This was significantly superior to 150 mg ranitidine b.d.s. which healed oesophagitis in 69.9% of patients (P 〈 0.001). Relief of reflux symptoms was superior with lansoprazole to that with ranitidine. Both lansoprazole and ranitidine were well tolerated with no serious drug-related adverse events noted. Conclusion: Lansoprazole, 30 mg once daily, is highly effective and safe in the short-term treatment of erosive oesophagitis.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2036.1995.tb00347.x

    Articles: DFG German National Licenses
  8. 8
    SANDERS, S. W. ; TOLMAN, K. G. ; GRESKI, P. A. ; JENNINGS, D. E. ; HOYOS, P. A. ; PAGE, J. G.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1992
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    This study examined the effects of dose and time of administration of lansoprazole on gastric pH and serum gastrin in healthy male volunteers. Three groups of six subjects received 10, 20 or 60 mg doses of lansoprazole or placebo. Doses were administered at 22.00 hours daily for 7 days. An additional 18 subjects received once daily 30 mg oral doses of lansoprazole or placebo; these subjects were dosed at either 08.00 hours or 22.00 hours in a randomized, crossover fashion with a 2-week washout period. Gastric pH was monitored for 24 h following the first and final dose, and 1 week following the completion of dosing.Lansoprazole, at all doses except 20 mg/day, significantly increased the median 24-hour gastric pH following 7 days of dosing (P 〈 0.05). In addition, morning dosing in the 30-mg crossover group led to a higher 24-h median pH than evening dosing (P= 0.003). There was no difference in night-time median pH between morning and evening dosing. Morning dosing also led to a significant increase in gastric pH on study Day 1 (P 〈 0.05). Plasma concentrations of lansoprazole were highly variable between subjects, but there was a significant correlation between AUC and the median 24-h gastric pH. Plasma concentrations and AUCs were higher on Day 7 than on Day 1 for subjects receiving 10 or 20 mg, but not for those receiving 30 or 60 mg doses. Lansoprazole bioavailability demonstrated a circadian effect manifested by higher plasma concentrations following morning dosing. Serum gastrin concentrations were elevated in all active medication groups.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2036.1992.tb00057.x

    Articles: DFG German National Licenses
  9. 9
    Kunde, V. G. ; Aikin, A. C. ; Hanel, R. A. ; Jennings, D. E. ; Maguire, W. C. ; Samuelson, R. E.

    [s.l.] : Nature Publishing Group
    Published 1981
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] THE Titan atmosphere is characterized by hydrocarbon and nitrogen-containing organic compounds in an atmosphere which near the surface is predominantly composed of molecular nitrogen, methane, molecular hydrogen and possibly argon1. Molecules containing oxygen have not been detected. Many organic ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/292686a0

    Articles: DFG German National Licenses
  10. 10
    Maguire, W. C. ; Hanel, R. A. ; Jennings, D. E. ; Kunde, V. G. ; Samuelson, R. E.

    [s.l.] : Nature Publishing Group
    Published 1981
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] THE Voyager 1 IR instrument (IRIS)1 obtained several hundred spectra of Titan when the angular diameter of the disk was at least five times the angular field of IRIS. Spectra of the centre of the disk, the polar regions, and both limbs all revealed the signatures of many hydrocarbons and of HCN in ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/292683a0

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The Earth's equatorial stratosphere shows oscillations in which the east–west winds reverse direction and the temperatures change cyclically with a period of about two years. This phenomenon, called the quasi-biennial oscillation, also affects the dynamics of the mid- and ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nature02142

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-2242
    Keywords:
    Brassica oleracea ; Mapping ; Meiosis ; Molecular markers ; Sex differences in recombination
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract Linkage maps of the nine chromosomes of Brassica oleracea, based on 75 informative molecular markers, have been compared in first and second backcross progeny from a cross between two doubled haploid lines. The second backcross progeny showed greater recombination frequencies for 75% of the pairs of adjacent markers, but there was no obvious indication that this effect was localised to particular regions of the chromosomes. Four chromosomes increased in genetic length more than twofold, while overall, the total map was 66% longer. The possible causes of this discrepancy are analysed. A sex difference in chiasma distribution and/or frequency at meiosis is thought to be the most likely explanation. The implications of this finding for mapping and map-based applications are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00223680

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1432-2242
    Keywords:
    Key words Brassica oleracea  ;  Mapping  ;   Meiosis  ;  Molecular markers  ;  Sex differences in recombination
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstact  Linkage maps of the nine chromosomes of Brassica oleracea, based on 75 informative molecular markers, have been compared in first and second backcross progeny from a cross between two doubled haploid lines. The second backcross progeny showed greater recombination frequencies for 75% of the pairs of adjacent markers, but there was no obvious indication that this effect was localised to particular regions of the chromosomes. Four chromosomes increased in genetic length more than twofold, while overall, the total map was 66% longer. The possible causes of this discrepancy are analysed. A sex difference in chiasma distribution and/or frequency at meiosis is thought to be the most likely explanation. The implications of this finding for mapping and map-based applications are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s001220050136

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    1572-9559
    Keywords:
    propyne ; infrared ; spectroscopy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Theν 5 andν 8 bands of propyne have been reinvestigated using a FTS spectrum between 900 and 1000 cm−1 with a resolution of 0.005 cm−1. About 1500 lines have been assigned. Some perturbations are clearly evident. Molecular parameters ofν 5=1 andν 8=1 levels were determined.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01010813

    Articles: DFG German National Licenses