Search Results - (Author, Cooperation:D. E. Brown)
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1Latest Papers from Table of Contents or Articles in PressWu, X., Hutson, I., Akk, A. M., Mascharak, S., Pham, C. T. N., Hourcade, D. E., Brown, R., Atkinson, J. P., Harris, C. A.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-04-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressS. Hao ; L. Cui ; D. Jiang ; X. Han ; Y. Ren ; J. Jiang ; Y. Liu ; Z. Liu ; S. Mao ; Y. Wang ; Y. Li ; X. Ren ; X. Ding ; S. Wang ; C. Yu ; X. Shi ; M. Du ; F. Yang ; Y. Zheng ; Z. Zhang ; X. Li ; D. E. Brown ; J. Li
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-03-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] INTERPLANETARY dust particles and meteorites yield invaluable insights into the processes, materials and environments that existed during the earliest history of the Solar System. Conventional meteorites are wonderful samples but they provide an incomplete perspective of the comets and asteroids ...Type of Medium: Electronic ResourceURL: -
4Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2016-01-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Articles: DFG German National LicensesWestre, E. D. ; Brown, D. E. ; Kutzner, J. ; George, S. M.
College Park, Md. : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The surface mobilities of both CO and K coadsorbed on Ru(001) were studied using laser-induced thermal desorption (LITD) techniques. The LITD measurements revealed that CO was essentially immobile on the potassium-promoted Ru(001) surface when the CO surface coverage, aitch-thetaCO, was less than the potassium coverage, aitch-thetaK. The CO surface mobility increased dramatically when aitch-thetaCO(approximately-greater-than)aitch-thetaK. At aitch-thetaK=0.10 ML and 315 K, the CO diffusion coefficient was DCO〈4×10−10 cm2/s for aitch-thetaCO〈0.10 ML and increased to DCO=2.5×10−7 cm2/s for aitch-thetaCO(approximately-greater-than)0.10 ML. At aitch-thetaK=0.25 ML and 315 K, the CO surface diffusion coefficient was DCO〈4×10−10 cm2/s for aitch-thetaCO〈0.25 ML and increased to DCO=5×10−9 cm2/s for aitch-thetaCO(approximately-greater-than)0.25 ML. The potassium surface mobility also decreased dramatically as a function of CO coverage at both aitch-thetaK=0.10 ML and aitch-thetaK=0.25 ML. These diffusion results are consistent with a mutually stabilizing and trapping interaction between coadsorbed CO and K with a 1:1 CO:K stoichiometry. The thermal desorption spectra of both CO and K were also studied using temperature programmed desorption (TPD) techniques. At aitch-thetaK=0.10 ML and CO coverages ranging from aitch-thetaCO=0.06 ML to aitch-thetaCO=0.42 ML, CO TPD peak temperatures were consistently higher than CO peak temperatures obtained on clean Ru(001). These TPD results indicate that CO is stabilized by K on Ru(001). In addition, the potassium TPD spectra at various CO coverages with aitch-thetaK=0.10 ML and aitch-thetaK=0.25 ML revealed that K was stabilized by coadsorbed CO. The experimental results for CO and K coadsorbed on Ru(001) argue for a mutually stabilizing, short-ranged trapping CO–K interaction with a 1:1 CO:K stoichiometry. Monte Carlo simulations based on this model for the CO:K interaction were also consistent with the coadsorbate surface diffusion results. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesArthur, J. ; Brown, D. E. ; Ruby, S. L. ; Brown, G. S. ; Shenoy, G. K.
[S.l.] : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: It is shown that the hyperfine field in a crystal can be characterized in a short measurement using resonant nuclear diffraction at a high-brightness synchrotron x-ray beamline. In addition to the strength of the field, this technique is sensitive to the field direction and to the crystal-structure factor of the nuclear sites. It is possible to separately measure the field at different crystallographic subgroups of nuclei. These principles are illustrated with an experiment using a crystal of 57Fe-enriched yttrium iron garnet, and future applications are discussed.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesTAYLOR, W. R. ; BROWN, D. E. 〈JR〉 ; EDWARDS, DARREL ; GUNDERSON, E. K. ERIC
Provincetown, Mass., etc. : Periodicals Archive Online (PAO)
Published 1974Staff ViewISSN: 0022-3980Topics: PsychologyURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0030-851XTopics: Political ScienceSociologyEconomicsNotes: Book ReviewsURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Summary The fungal micro-organism Trichoderma reesei was grown in batch culture with excess glucose at pH values between 2.7 and 4.5 and temperatures between 25°C and 35°C. A maximum lipid concentration of 16.9% of the cell dry weight was achieved at pH 3.2 and a temperature of 27°C. Lipid concentration was shown to be correlated with a calculated maximum specific growth rate (µ mc ) and the maximum lipid value occurred at µ mc = 0.10 h−1. Fatty acid analysis was carried out and found to change with changing pH and temperature. Palmitic (16:0) acid and unusually high proportions of stearic acid (18:0) were commonly present. A conversion of fatty acids to palmitoleic acid (16:1) occurred following an unidentified nutrient limitation other than nitrogen depletion after 70 h of culture.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The discovery of an in vitro contraction cycle by Goodall and A. G. Szent Gy rgyi4 provides a model of activation which works simply through small changes of pH. It is of interest, therefore, to see how far this system resembles intact muscle in its reaction to pressure. First the dependence of ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1420-9136Keywords: Eddy diffusion coefficients ; Atmosphere 30–60 kmSource: Springer Online Journal Archives 1860-2000Topics: GeosciencesPhysicsNotes: Abstract The results of numerical models or of new observational programs are checked by comparing them with past observations. Also, it is desirable that the eddy diffusion coefficients used in two-dimensional models be derived from the same data set as the circulation statistics which the model outputs are checked against, so that all results refer to the same atmospheric conditions. For the first time, the three components of the eddy diffusion matrix, from 30–60 km, 80°N–10°S are computed, together with the means, variances and covariances of the wind and temperature through the same region using the same data set for 1960–76 and the same handling and analysis methods for all variables. Horizontal diffusivities,K yy , are obtained from the variance and integral time scale of the meridional wind speed. The present values are generally smaller than past estimates, presumably because temporal variations longer than a month have been removed in this work. Estimates ofK yz are based on the tentative assumption that the diffusivity is proportional to the slope of isentropic surfaces, and estimates ofK zz are based on the assumption that small-scale gravity waves are primarily responsible for vertical mixing.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1432-1009Keywords: Data validation ; Quality assurance ; Contract laboratory programSource: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Abstract Data validation, as prescribed in guidance documents provided by the United States Environmental Protection Agency (EPA), yields legal evidence that an analytical laboratory has performed analyses according to predetermined specifications. This validation process, because it involves only the checking of procedural documentation, provides minimal information concerning the technical validity of the data. Unfortunately, in the minds of many, the performance of such a data validation has become synonymous with technical validity. A better approach is to implement a routine program of referee analyses. That is, submit a predetermined number of samples from the project to a second laboratory. A routine program of this type provides a self-checking and self-correcting mechanism for determining whether data are technically valid.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesEder, R. ; Berkers, I. ; Brown, D. E. ; Grand, I. S. ; Hagn, E. ; Harding, P. ; Hassani, R. ; Herzog, P. ; Kastelein, B. ; Knipper, A. ; Marguier, G. ; Massao, M. ; Ohya, S. ; Postma, H. ; Prinz, J. ; Richard-Serre, C. ; Romanski, I. ; Schlösser, K. ; Stone, N. J. ; Vanderpoorten, W. ; Vanhaverbeke, J. ; Vanneste, L. ; Wölfle, T. ; Zech, E.
Springer
Published 1990Staff ViewISSN: 1572-9540Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract This paper presents off-line and on-line orientation results obtained with the new on line nuclear orientation device NICOLE in CERN. Magnetic moments of187,185Pt g and186Ir m , electric quadrupole moment ratios between Pt isotopes with mass number 185, 187 and 189, the spin of the 2 h isomer of186Ir and a new decay scheme of184Au involving a metastable state are established. The shape variation versus mass number of the Pt isotopes leads to sign change of the spectroscopic quadrupole moment between A=187 and 185.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary Examples of linear growth are reviewed and some are identified with conservative trace nutrient limitation. A kinetic description of the limitation mechanism is proposed and shown to describe the limited batch culture ofBacillus subtilis.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary The cell is considered to be divided into nucleic acids, proteinaceous material and storage compounds. The enzyme is believed to be constitutive but repressed by the rate of catabolism. A structured model is developed to describe the growth, amylase production and dissolved oxygen profile in the batch culture ofAspergillus oryzae.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1573-6784Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary The Exactech blood glucose biosensor has been used successfully to measure glucose concentrations in fermentation broths. A highly sensitive linear calibration was obtained between the glucose concentration and the biosensor reading, which correlated well with a Reducing Sugar Assay.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesBrown, D. E. ; Thrall, M. A. ; Walkley, S. U. ; Wurzelmann, S. ; Wenger, D. A. ; Allison, R. W. ; Just, C. A.
Springer
Published 1996Staff ViewISSN: 1573-2665Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Niemann-Pick disease type C (NPC) is an autosomal recessive neurovisceral lysosomal storage disorder in which cholesterol lipidosis results from defective intracellular transport of unesterified cholesterol. The primary molecular defect of NPC is unknown; regulatory mechanisms of cholesterol metabolism are impaired, resulting in retarded esterification of exogenous cholesterol with accumulation of unesterified cholesterol in lysosomes and secondary storage of glycolipids and sphingomyelin. In obligate heterozygotes from a feline NPC model, cultured skin fibroblasts challenged with exogenously derived cholesterol exhibited intermediate rates of cholesterol esterification and accumulation of unesterified cholesterol. Liver lipid analyses of obligate heterozygote cats demonstrated intermediate cholesterol and sphingomyelin concentrations. Vacuolated skin fibroblasts were found in 2 of 3 heterozygote cats, and occasional cortical neurons exhibited intracellular inclusions immunoreactive for GM2-ganglioside. Ultrastructural studies provided evidence of storage in liver and brain. We believe these morphological and biochemical findings are the first example of manifestations of CNS abnormalities in a genetic carrier for a neuronal storage disease.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary A novel filter housing has been designed that permits the use of a coarse sintered stainless steel cylindrical filter element as a cross-flow filtration unit. Cultures of the fungal micro-organism Trichoderma reesei have been used to study the performance characteristics of the unit and filtration rates of 1.0m3/m2/h have been achieved in a sterile manner.Type of Medium: Electronic ResourceURL: