Search Results - (Author, Cooperation:D. Doherty)

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  1. 1
    Staff View
    Publication Date:
    2018-10-02
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-11-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cephalometry ; Child ; Child Development Disorders, Pervasive/*genetics ; Child, Preschool ; Chromatin Assembly and Disassembly ; Cohort Studies ; DNA Probes ; DNA-Binding Proteins/genetics ; Exome ; Female ; *Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Male ; Megalencephaly/genetics ; Microcephaly/genetics ; *Mutation ; Nuclear Proteins/genetics ; PTEN Phosphohydrolase/genetics ; Protein-Serine-Threonine Kinases/genetics ; Protein-Tyrosine Kinases/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, N-Methyl-D-Aspartate/genetics ; Repressor Proteins/genetics ; Sequence Analysis, DNA/*methods ; T-Box Domain Proteins/genetics ; Transcription Factors/genetics ; beta Catenin/genetics/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Paech, M. J. ; Lim, C. B. ; Banks, S. L. ; Rucklidge, M. W. M. ; Doherty, D. A.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Twenty-four gynaecological patients receiving postoperative patient-controlled analgesia were enrolled in an open cross-over pilot study evaluating two new formulations of nasal fentanyl spray. The primary outcome was the bioavailability of nasal fentanyl in comparison with intravenous fentanyl. This manuscript describes the clinical outcomes of quality of postoperative analgesia and patient acceptability. There were 21 complete data sets for both sequences of the cross-over design. In randomised order, patients received approximately 50 μg of fentanyl in a single dose by intranasal and intravenous administration, but separated by at least 2 h. Analgesia was of rapid onset (within 5 min) and similar quality. There was no significant difference in side-effects. Four patients experienced mild nasal stinging and although 10 (42%) preferred intravenous administration, seven (29%) preferred intranasal and six (25%) had no preference. We conclude that these formulations of fentanyl, delivered as nasal spray, have potential clinical utility.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2044.2003.03286.x

    Articles: DFG German National Licenses
  4. 4
    Ellen, P. ; Parko, E.M. ; Wages, C. ; Doherty, D. ; Herrmann, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0023-9690
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Education
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0023-9690(82)90030-3

    Articles: DFG German National Licenses
  5. 5
    Paech, M. J. ; Tweedie, O. ; Stannard, K. ; Hepp, M. ; Dodd, P. ; Daly, H. ; Bennett, E.-J. ; Millard, A. ; Doherty, D. A.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    We performed a randomised, crossover, single-blind trial among 168 patients, to compare the single-use SoftSeal™ and LMA Unique™ laryngeal mask airways in spontaneously breathing adults. Size-3 and -4 laryngeal mask airways, inserted by experienced anaesthetists, performed equivalently for successful first-time placement (148 (91%) vs 155 (96%) for the SoftSeal™ and LMA Unique™, respectively). The SoftSeal™ was more often rated as difficult to insert (27 (17%) vs 4 (3%); p 〈 0.001) and was more likely to show evidence of mucosal trauma after the first insertion (14 (10%) vs 5 (4%); OR 1.3 (95% CI 1.3–11.3); p 〈 0.05). The fibreoptic view of the larynx was better through the SoftSeal™ (vocal cords not visible in 27 (17%) vs 44 (27%); p 〈 0.05) and it more frequently provided a ventilation seal at 20 cmH2O (93 (59%) vs 62 (39%); OR 2.15 (CI 1.44–3.21); p 〈 0.001). In contrast to the LMA Unique™, its cuff pressure did not increase during nitrous oxide anaesthesia (median (IQR [range]) decrease 3 (− 20–23 [-40–94]) cmH2O vs increase of 16 (−2–39 [−54–112]) cmH2O; p 〈 0.01). Both devices were equivalent for the success of first-time insertion and performed satisfactorily clinically. There were some performance differences, but either appears suitable for airway management in spontaneously breathing patients.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2044.2005.04122.x

    Articles: DFG German National Licenses
  6. 6
    Corrado, R.R. ; Doherty, D. ; Glackman, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0160-2527
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Psychology
    Law
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0160-2527(89)90009-5

    Articles: DFG German National Licenses