Search Results - (Author, Cooperation:D. B. Wilson)

2015-04-02

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Age of Onset ; Aging/genetics/*physiology ; Animals ; Animals, Newborn ; Diet, High-Fat ; Female ; Genetic Predisposition to Disease ; Heart/physiology/physiopathology ; Heart Diseases/*congenital/etiology/genetics/*prevention & control ; Homeodomain Proteins/genetics ; Hyperglycemia ; *Maternal Age ; Mice ; Obesity ; Ovary/transplantation ; Phenotype ; Physical Conditioning, Animal/*physiology ; Pregnancy ; Pregnancy, Animal/genetics/*physiology ; Quantitative Trait Loci/genetics ; Risk ; Transcription Factors/genetics

2018-01-26

American Society of Hematology (ASH)

0006-4971

1528-0020

Biology

Medicine

Hematopoiesis and Stem Cells, Pediatric Hematology, Phagocytes, Granulocytes, and Myelopoiesis

2018-08-02

Royal Society

2054-5703

Natural Sciences in General

computational biology, computational mathematics, computer modelling and simulation

1365-2494

Blackwell Publishing Journal Backfiles 1879-2005

Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

The re growth of S24 ryegrass (Lolium perenne L.) plants was studied during 4 days, following defoliation to stuhble heights of 2, 4, 6, 8, 10 and 12 cm. The weight of regrowth produced by plants cut to 6-cm stubhie heights and higher was equal to the weight increment of uncut plants above the same heights. During the 4 days the weight of the stubble segment between 0 and 2 cm decreased in plants cut to 2 or 4 cm, but was maintained or increased in plants cut to 6 cm or higher. Weights of the 2- to 4- to 6-cm stubble segments were just maintained at the lower cutting heights, but were increased by the same amount as in uncut plants at the highest cutting height. The percentage of water-soluble carbohydrates in all stubble segments decreased following defoliation, but the percentage of N did not change. Root weights were either maintained or increased, depending on the severity of cutting. In relation to grazing experiments, it is pointed out that where DM disappearance is taken as the difference hetween yield on a protected site and residue on a grazed site, too close cutting of the sample areas will give an overestimate of yield.

Electronic Resource

1420-9071

Springer Online Journal Archives 1860-2000

Biology

Medicine

Résumé Le cervelet des souris hétérozygotes de la mutation «lurcher» (Lc) présentent des anomalies. Il est réduit et déformé, en particulier l'uvula vermis. On peut détecter ces anomalies chez le nouveau-né de 3 jours avant l'apparition des aberrations du comportement.

Electronic Resource

1432-0800

Springer Online Journal Archives 1860-2000

Energy, Environment Protection, Nuclear Power Engineering

Medicine

Summary Top dressing a spray-irrigated pasture of orchardgrass with 125 t/ha of overwintered beef feedlot manure almost doubled the yield of dry forage: 6 353 kg/ha vs. 3578 kg/ha for the plots receiving no manure. Even at this rate of application, the manure did not contaminate the irrigated grass with enteropathogenic bacteria after irrigation. When the grass became contaminated through the use of fecally polluted irrigation water, the fecal coliforms, indicator organisms with survival characteristics similar to the salmonellae, were effectively eliminated from the grass after exposure to 65 hr of bright sunlight.

Electronic Resource

1432-0533

Cerebral blood vessels ; “Overgrowth” ; Embryonic development ; Electron microscopy

Springer Online Journal Archives 1860-2000

Medicine

Summary Cerebral capillaries in “overgrown” neural tissue of chick embryo brains ranging in age from 5–18 days of incubation were studied by means of electron microscopy. The vessels in the abnormal tissue showed more extensive and prolonged interdigitations and overlapping of adjacent endothelial cells than did those in normal control brains. In the abnormal neural tissue the appearance and distribution of endothelial cell organelles was similar to that in normal tissue; however, the Golgi complex was less highly developed, and there was an increased amount of coated vesicles in the capillaries of the abnormal brains.

Electronic Resource

1432-0533

Acid phosphatase ; Mouse ; Embryo ; Hindbrain ; Dysraphism

Springer Online Journal Archives 1860-2000

Medicine

Summary The cytochemical localization of acid phosphatase (AP) was studied at the ultrastructural level in the abnormal neuroepithelium of dysraphic loop-tail (Lp/Lp) embryos between 9 and 12 days of gestation. At 9–11 days, normal and abnormal embryos showed a positive AP reaction throughout the thickness of the neuroepithelium, i.e., in apical, intermediate, and basal zones, although many cells were unreactive. The reaction is sensitive to sodium fluoride and occurs in saccules and vesieles associated with the Golgi complex as well as in vacuoles of varying size containing flocculent and particulate material. Gap-junctional vesicles, which are known to occur in increased numbers in abnormal brains, were AP-negative. By 12 days of gestation, the reaction in normal embryos was localized in the midventral marginal layer, where some cell processes were filled with reaction product; in abnormal embryos, these AP-positive processes were not observed. The results indicate that perturbations in lysosomal activity may not be fundamentally involved in the etiology of dysraphism in this mutant.

Electronic Resource

1432-0533

Cerebral vessels ; Telencephalon ; Looptail mutant mouse ; Pathogenesis ; Electron microscopy

Springer Online Journal Archives 1860-2000

Medicine

Summary Cerebral capillaries in the telencephalon of normal (+/+;Lp/+)_and abnormal (Lp/Lp) loop-tail mutant mice were studied chronologically by means of electron microscopy at stages ranging from 15 through 18 days of gestation. In the abnormal tissue, neural rosettes were common, and cellular material and red blood cells were often contained within the lumen of the rosettes. The endothelial cells of telencephalic blood vessels in the abnormal brains showed a persistence of cellular projections, subluminal vacuoles, and swollen mitochondria beyond the stage when these features ordinarily disappear in normal embryonic cerebral vessels. The endothelial cells in the abnormal brains also failed to become fully invested with pericytes, and red blood cells gradually infiltrated the neural tissue, particularly in subependymal regions, at 16–18 days of gestation.

Electronic Resource

1432-0533

Neural folds ; Embryo ; Spina bifida ; Neuroepithelium ; Neural crest

Springer Online Journal Archives 1860-2000

Medicine

Summary Ultrastructural pathology in the apical neural folds was analyzed by means of tannic acid (TA) and ruthenium red (RR) cytochemistry in abnormal (vl/vl) mutant mouse embryos ranging in age from 17–35 somites. At lumbosacral levels of the spinal cord where closure fails to occur, as well as at more cranial levels where closure occurs but results in dorsal midline abnormalities, normal deposition of TA-positive and RR-positive material occurred in the space that develops between the overlying surface ectoderm (SE) and neuroepithelium (NE). However, in lumbosacral regions, pleomorphic excrescences projected abnormally from the apices of the transitional zone cells between SE and NE cells of the open neural folds. These abnormal projections consisted of enlarged cytoplasmic blebs, as well as entire cells. The cells were not necrotic nor did they show evidence of incipient degeneration. However, it is possible that they represent aberrant putative neural crest cells, as indicated by their location in the transitional zone and by the filopodia and lamellipodia projecting from their luminal surfaces.

Electronic Resource

1476-4687

Nature Archives 1869 - 2009

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

[Auszug] What might be construed as a serious challenge to this thesis are the reports of Najarian and Feldman of the transferability of sensitivity to skin homografts in mice and guinea-pigs by means of viable suspensions of ?immune? lymphoid cells, enclosed within cell-impenetrable ?Millipore? diffusion ...

Electronic Resource

1476-4687

Nature Archives 1869 - 2009

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

[Auszug] The construction of disk models in the standard approach, due to the school of Abramowicz, is straightforward23. For an axisymmetric stationary space-time, the metric has the form4 ds2= -e2v at2+r2B2 sin2 ? e2?(?f - ? at)2 + e2/A(dr2+r2dlt;92) (1) where zgt;, , ? and B are functions of polar ...

Electronic Resource

1422-6960

Key words. Galileo; Catholic Church; historiography; science and religion.

Springer Online Journal Archives 1860-2000

Physics

science and religion. The Church concluded that the plainest facts of human experience agreed perfectly with an omniscient God's revealed word to proclaim the earth at rest. Supported by the Bible, Galileo, God-like, linked the elegance of mathematics to truths about nature. The Church, in effect, resisted Galileo's claim to be able to think like God, instead listening to God himself – and paying close attention to what man himself observed. We can thus see that the phrase “Galileo's religion versus the Church's science” is as meaningful (or meaningless) as the usual designation “Galileo's science versus the Church's religion.”

Electronic Resource

1573-6784

Springer Online Journal Archives 1860-2000

Process Engineering, Biotechnology, Nutrition Technology

Summary A relatively simple system is described which yields high concentrations of cell mass and plasmid encoded protein. The maximum concentrations of cell mass and of a plasmid encoded protein, β-lactamase, obtained were: 49 g/L dry weight and 1.4 g/L, respectively.

Electronic Resource

0029-5981

Engineering ; Engineering General

Wiley InterScience Backfile Collection 1832-2000

Mathematics

Technology

3 Tab.

Electronic Resource

0006-3592

cellulases ; cellulose ; fragmentation ; hydrolysis ; synergism ; Thermomonospora fusca ; Trichoderma reesei ; Chemistry ; Biochemistry and Biotechnology

Wiley InterScience Backfile Collection 1832-2000

Biology

Process Engineering, Biotechnology, Nutrition Technology

In this study, the fragmentation activities of Thermomonospora fusca cellulases E2, E3, E5, Trichoderma reesei CBHI, and their mixtures were measured to study synergism in fragmentation. Fragmentation studies revealed that only two pure cellulases, T. fusca E2 and E5 had significant fragmentation activity. T. fusca E3 shows strong synergism in fragmentation both in the production of reducing sugars and in fragmentation with both T. fusca endoglucananses and with T. reesei CBHI. Most mixtures containing CBHI produced higher rates of fragmentation than comparable mixtures containing E3. The highest rate and extent of reducing sugar formation and the highest fragmentation activity were obtained with a mixture of E2, E3, and CBHI. © 1992 John Wiley & Sons, Inc.

2 Ill.

Electronic Resource

0006-3592

Caldocellum saccharolyticum ; cellulose ; binding ; β-glucosidase ; hydrolysis ; mole fraction ; synergism ; Thermomonospora fusca ; Trichoderma reesei ; Chemistry ; Biochemistry and Biotechnology

Wiley InterScience Backfile Collection 1832-2000

Biology

Process Engineering, Biotechnology, Nutrition Technology

In this study, different mole fractions of pure Thermomonospora fusca E5 and E3, plus Trichoderma reesei CBHI were studied for reducing sugar production at 2 h, degree of synergism, and cellulose binding. In addition, the effects of introducing the Caldocellum saccharolyticum β-glucosidase into this cellulase system were investigated. The cellulases used were purified to homogeneity. Avicel PH 102 (4% w/w solution in 0.05 sodium acetate pH 5.5 buffer) was the substrate. Reactions were run at 50°C for 2 h using total cellulase concentrations of 8.3 or 12.2 μM. A bimixture of T. fusca E3 and T. reesei CBHI was very effective in hydrolyzing microcrystalline cellulose (9.1% conversion). The addition of endoglucanase E5 to the mixture only increased conversion to 9.8%. However, when both E5 and β-glucosidase were added, conversion increased to 14%. It was also observed that increasing total cellulase concentration beyond 8.3 μM did little to increase percent conversion of cellulose into glucose. The results of the binding studies indicate no competition for binding sites between the endo- and exocellulases. © 1993 John Wiley & Sons, Inc.

7 Ill.

Electronic Resource