Search Results - (Author, Cooperation:D. B. Johnson)
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1Latest Papers from Table of Contents or Articles in PressA. Kaur ; M. R. Webster ; K. Marchbank ; R. Behera ; A. Ndoye ; C. H. Kugel, 3rd ; V. M. Dang ; J. Appleton ; M. P. O'Connell ; P. Cheng ; A. A. Valiga ; R. Morissette ; N. B. McDonnell ; L. Ferrucci ; A. V. Kossenkov ; K. Meeth ; H. Y. Tang ; X. Yin ; W. H. Wood, 3rd ; E. Lehrmann ; K. G. Becker ; K. T. Flaherty ; D. T. Frederick ; J. A. Wargo ; Z. A. Cooper ; M. T. Tetzlaff ; C. Hudgens ; K. M. Aird ; R. Zhang ; X. Xu ; Q. Liu ; E. Bartlett ; G. Karakousis ; Z. Eroglu ; R. S. Lo ; M. Chan ; A. M. Menzies ; G. V. Long ; D. B. Johnson ; J. Sosman ; B. Schilling ; D. Schadendorf ; D. W. Speicher ; M. Bosenberg ; A. Ribas ; A. T. Weeraratna
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-04-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Aging/*metabolism ; Animals ; Cell Line, Tumor ; Culture Media, Conditioned/pharmacology ; DNA Damage ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; Disease Progression ; *Drug Resistance, Neoplasm ; Fibroblasts/secretion ; Humans ; Indoles/pharmacology/therapeutic use ; Male ; Melanoma/blood supply/*drug therapy/genetics/*pathology ; Membrane Proteins/*metabolism/secretion ; Mice ; Microphthalmia-Associated Transcription Factor/metabolism ; Middle Aged ; Molecular Targeted Therapy ; *Neoplasm Metastasis ; Neovascularization, Pathologic ; Oxidative Stress ; Phenotype ; Reactive Oxygen Species/metabolism ; Sulfonamides/pharmacology/therapeutic use ; *Tumor Microenvironment ; Wnt Signaling Pathway ; Wnt1 Protein/antagonists & inhibitors ; beta Catenin/metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressJohnson, D. B., Bordeaux, J., Kim, J. Y., Vaupel, C., Rimm, D. L., Ho, T. H., Joseph, R. W., Daud, A. I., Conry, R. M., Gaughan, E. M., Hernandez-Aya, L. F., Dimou, A., Funchain, P., Smithy, J., Witte, J. S., McKee, S. B., Ko, J., Wrangle, J. M., Dabbas, B., Tangri, S., Lameh, J., Hall, J., Markowitz, J., Balko, J. M., Dakappagari, N.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-11-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressKugel, C. H., Douglass, S. M., Webster, M. R., Kaur, A., Liu, Q., Yin, X., Weiss, S. A., Darvishian, F., Al-Rohil, R. N., Ndoye, A., Behera, R., Alicea, G. M., Ecker, B. L., Fane, M., Allegrezza, M. J., Svoronos, N., Kumar, V., Wang, D. Y., Somasundaram, R., Hu-Lieskovan, S., Ozgun, A., Herlyn, M., Conejo-Garcia, J. R., Gabrilovich, D., Stone, E. L., Nowicki, T. S., Sosman, J., Rai, R., Carlino, M. S., Long, G. V., Marais, R., Ribas, A., Eroglu, Z., Davies, M. A., Schilling, B., Schadendorf, D., Xu, W., Amaravadi, R. K., Menzies, A. M., McQuade, J. L., Johnson, D. B., Osman, I., Weeraratna, A. T.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-11-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-12-15Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1365-2389Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: One of the characteristics of soils located within the cores of stockpile storage mounds at opencast mine sites is their accumulation of ammonium-nitrogen. Two areas of restored land were constructed from soil stockpiled for 3 years; one consisted of mound-surface (‘aerobic zone’) soil, and the other of deeply buried (‘anaerobic zone’) soil. In that constructed from mound-surface soil, concentrations of both ammonium- and nitrate-nitrogen remained fairly stable throughout the first 6 months of restoration at about 12–20 μg g−1, but in the site constructed from deeply buried soil, concentrations of ammonium-N decreased from an initial high of 160 to 14 μg N g−1 soil after 14 weeks, and increased again to 42 μg N g−1 soil by week 29. In contrast, concentrations of nitrate-nitrogen at the latter site increased from an initial 9 μg to a maximum recorded level of 77 μg N g−1 soil by week 14, before subsiding to 9 μg N g−1 soil by week 29. Nitrate was considered to have been lost from the restored soils by a combination of leaching and denitrification, as no vegetation was established at these sites. After a short-term stimulation following restoration, soil microbial biomass levels remained fairly constant, though soils (up to 3 years after restoration) were characterized by a very small ratio of biomass C: organic C.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesNotes: Abstract A crown-of-thorns starfish control program was conducted at Grub Reef (central Great Barrier Reef) in an area (0.64 km2) which encompassed 53 individual patch reefs. During a two week period, 15 divers injected 3175 starfish with copper sulphate. The program was considered unsuccessful. Although starfish abundance had declined significantly after the control efforts, biological surveys indicated that a relatively large number of starfish remained. The surveys also indicated a general decline in the number of starfish along the reef perimeter, outside the control area. The total cost of the control program was $35 per starfish. These results have important implications for the implementation of future control programs and highlight the need to undertake before and after biological surveys to assess the effectiveness of the control efforts.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesJohnson, D. B. ; Moran, P. J. ; Baker, V. J. ; Christie, C. A. ; Miller, I. R. ; Miller-Smith, B. A. ; Thompson, A. A.
Springer
Published 1992Staff ViewISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesBaker, V. J. ; Bass, D. K. ; Christie, C. A. ; Johnson, D. B. ; Miller, I. R. ; Miller-Smith, B. A. ; Moran, P. J. ; Thompson, A. A.
Springer
Published 1990Staff ViewISSN: 1432-0975Source: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1432-0541Keywords: Optimal parallel and sequential algorithms ; EREW PRAM model ; Vertex updating ; Minimum spanning treeSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceMathematicsNotes: Abstract The vertex updating problem for a minimum spanning tree (MST) is defined as follows: Given a graphG=(V, E G) and an MSTT forG, find a new MST forG to which a new vertexz has been added along with weighted edges that connectz with the vertices ofG. We present a set of rules that produce simple optimal parallel algorithms that run inO(lgn) time usingn/lgn EREW PRAM processors, wheren=¦V¦. These algorithms employ any valid tree-contraction schedule that can be produced within the stated resource bounds. These rules can also be used to derive simple linear-time sequential algorithms for the same problem. The previously best-known parallel result was a rather complicated algorithm that usedn processors in the more powerful CREW PRAM model. Furthermore, we show how our solution can be used to solve the multiple vertex updating problem: Update a given MST whenk new vertices are introduced simultaneously. This problem is solved inO(lgk·lgn) parallel time using (k·n)/(lgk·lgn) EREW PRAM processors. This is optimal for graphs having Ω (kn) edges.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesThornton, D. ; Flynn, A. ; Johnson, D. B. ; Ryan, P. D.
New York, NY [u.a.] : Wiley-Blackwell
Published 1975Staff ViewISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: The suitability of hornblende as a support for immobilized β-fructofuranosidase (invertase) was studied, with regard to the physical stability of the support and the thermal and operational stability of the immobilized enzyme. Hornblende was more stable than Enzacryl-Alo or Enzacryl-TIO, and marginally more stable than porous glass. Invertase immobilized on hornblende was more stable during long-term operation than invertase immobilized on porous glass. An active preparation of immobilized invertase was obtained also on pyroxene particles.Additional Material: 8 Ill.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyAdditional Material: 2 Ill.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Glucoamylase from four different companies was studied: three had similar stability (half-life at 50°C about 140 hr); the fourth was less stable (half-life at 50°C about 20 hr). The immobilized enzymes were all less stable than their soluble counterparts: immobilized enzyme stability depended on the soluble enzyme used, the support, and method of immobilization. Thus enzyme bound to Enzacryl-TIO was less stable than enzyme bound to hornblende (metal-link method); this, in turn, was less stable than enzyme bound to hornblende by a silane-glutaraldehyde process. Bound enzyme stability was also improved by the presence of substrate or product (starch maltose or glucose). After 110 hr at 50°C in the presence of maltose (10% (w/v)) one preparation (a more stable soluble enzyme boul1d to hornblende by a silane-glutaraldehyde process) retained over 95% of its activity: activity loss was too low to permit the estimation of a half-life.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyAdditional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyAdditional Material: 1 Ill.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: The stability of immobilized preparations of xanthine oxidase and urate oxidase was studied, and optimized, because of the potential joint use of both enzymes in clinical analysis. Xanthine oxidase was immobilized on cellulose, Sepharose, hornblende, Enzacryl-TIO, and Porous glass. The half-lives of these preparations at 30°C ranged from 40 min to 5.0 hr. In this respect immobilized enzyme resembled soluble enzyme in dilute solution (0.11 mg/ml), when the half-live was about 3.5 hr. More concentrated enzyme solution (1 mg/ml), had a half-life of 64 hr, and was, therefore, considerably more stable than the untreated immobilized xanthine oxidase preparations. Inclusion of albumen in storage and assay buffer increased the half-life of bound xanthine oxidase. So also did treatment with glutaraldehyde: in the case of xanthine oxidase bound to Enzacryl-TIO such treatment increased the half-life at 30°C from 3 hr to about 100 hr. Immobilized xanthine dehydrogenase was more stable than immobilized xanthine oxidase: the dehydrogenase lost no activity during continuous assay for 5 hr at 30°C. The stability of immobilized urate oxidase depended on the quantity of enzyme used and on the time of stirring during immobilization: thus a preparation was made (by stirring urate oxidase (48 mg/g support) with Enzacryl-TIO for 24 hr) which lost no activity during 350 hr at 30°C.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: