Search Results - (Author, Cooperation:D. A. Fidock)

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  1. 1
    D. A. Fidock
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-07-03
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Antimalarials/*administration & dosage ; Artemisinins/*administration & dosage ; Child ; DNA Mismatch Repair/*genetics ; Disease Eradication/*methods ; Drug Resistance/*genetics ; Humans ; Malaria, Falciparum/parasitology/*prevention & control ; Mutation ; Plasmodium falciparum/drug effects/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-12-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Antimalarials/*pharmacology ; Artemisinins/*pharmacology ; Cambodia ; Drug Resistance/*genetics ; Genetic Loci ; Humans ; Malaria, Falciparum/drug therapy/parasitology ; Molecular Sequence Data ; Mutation ; Plasmodium falciparum/*drug effects/*genetics ; Protein Structure, Tertiary ; Protozoan Proteins/chemistry/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2011-11-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antimalarials/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Cell Line, Tumor ; *Drug Discovery ; Drug Evaluation, Preclinical ; Drug Resistance ; Erythrocytes/parasitology ; Humans ; Imidazoles/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Liver/*parasitology ; Malaria/*drug therapy/parasitology/prevention & control ; Mice ; Mice, Inbred BALB C ; Molecular Structure ; Piperazines/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Plasmodium/cytology/*drug effects/growth & development/physiology ; Plasmodium berghei/cytology/drug effects/growth & development/physiology ; Plasmodium falciparum/cytology/drug effects/growth & development/physiology ; Plasmodium yoelii/cytology/drug effects/growth & development/physiology ; Polymorphism, Single Nucleotide ; Protozoan Proteins/chemistry/genetics/metabolism ; Random Allocation ; Small Molecule Libraries ; Sporozoites/drug effects/growth & development
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2013-11-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    1-Phosphatidylinositol 4-Kinase/*antagonists & ; inhibitors/chemistry/genetics/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Binding Sites ; Cytokinesis/drug effects ; Drug Resistance/drug effects/genetics ; Fatty Acids/metabolism ; Female ; Hepatocytes/parasitology ; Humans ; Imidazoles/metabolism/pharmacology ; Life Cycle Stages/drug effects ; Macaca mulatta ; Malaria/*drug therapy/*parasitology ; Male ; Models, Biological ; Models, Molecular ; Phosphatidylinositol Phosphates/metabolism ; Plasmodium/classification/*drug effects/*enzymology/growth & development ; Pyrazoles/metabolism/pharmacology ; Quinoxalines/metabolism/pharmacology ; Reproducibility of Results ; Schizonts/cytology/drug effects ; rab GTP-Binding Proteins/genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    B. Baragana ; I. Hallyburton ; M. C. Lee ; N. R. Norcross ; R. Grimaldi ; T. D. Otto ; W. R. Proto ; A. M. Blagborough ; S. Meister ; G. Wirjanata ; A. Ruecker ; L. M. Upton ; T. S. Abraham ; M. J. Almeida ; A. Pradhan ; A. Porzelle ; M. S. Martinez ; J. M. Bolscher ; A. Woodland ; S. Norval ; F. Zuccotto ; J. Thomas ; F. Simeons ; L. Stojanovski ; M. Osuna-Cabello ; P. M. Brock ; T. S. Churcher ; K. A. Sala ; S. E. Zakutansky ; M. B. Jimenez-Diaz ; L. M. Sanz ; J. Riley ; R. Basak ; M. Campbell ; V. M. Avery ; R. W. Sauerwein ; K. J. Dechering ; R. Noviyanti ; B. Campo ; J. A. Frearson ; I. Angulo-Barturen ; S. Ferrer-Bazaga ; F. J. Gamo ; P. G. Wyatt ; D. Leroy ; P. Siegl ; M. J. Delves ; D. E. Kyle ; S. Wittlin ; J. Marfurt ; R. N. Price ; R. E. Sinden ; E. A. Winzeler ; S. A. Charman ; L. Bebrevska ; D. W. Gray ; S. Campbell ; A. H. Fairlamb ; P. A. Willis ; J. C. Rayner ; D. A. Fidock ; K. D. Read ; I. H. Gilbert
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-06-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antimalarials/administration & dosage/adverse ; effects/pharmacokinetics/*pharmacology ; Drug Discovery ; Female ; Gene Expression Regulation/*drug effects ; Life Cycle Stages/drug effects ; Liver/drug effects/parasitology ; Malaria/drug therapy/*parasitology ; Male ; Models, Molecular ; Peptide Elongation Factor 2/antagonists & inhibitors/metabolism ; Plasmodium/*drug effects/genetics/growth & development/*metabolism ; Plasmodium berghei/drug effects/physiology ; Plasmodium falciparum/drug effects/metabolism ; Plasmodium vivax/drug effects/metabolism ; Protein Biosynthesis/*drug effects ; Quinolines/administration & dosage/chemistry/pharmacokinetics/*pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    B. S. Crabb ; J. G. Beeson ; R. Amino ; R. Menard ; A. Waters ; E. A. Winzeler ; M. Wahlgren ; D. A. Fidock ; S. Nwaka
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-04-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Anopheles/parasitology/physiology ; Antigens, Protozoan/immunology ; Antimalarials/pharmacology/therapeutic use ; Artemisinins/pharmacology/therapeutic use ; Biomedical Research/organization & administration/*trends ; Drug Resistance/drug effects ; Erythrocytes/parasitology ; Female ; Hepatocytes/parasitology ; Humans ; Malaria/*drug therapy/epidemiology/immunology/*prevention & control ; Malaria Vaccines/immunology ; Mosquito Control/methods ; Plasmodium/drug effects/growth & development/immunology/metabolism ; Primaquine/administration & dosage/adverse effects/metabolism/therapeutic use ; Sporozoites/immunology ; Vaccines, Attenuated/immunology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    J. Yuan ; K. C. Cheng ; R. L. Johnson ; R. Huang ; S. Pattaradilokrat ; A. Liu ; R. Guha ; D. A. Fidock ; J. Inglese ; T. E. Wellems ; C. P. Austin ; X. Z. Su
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-08-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Antimalarials/chemistry/*pharmacology ; Biological Evolution ; Chromosome Mapping ; Drug Combinations ; *Drug Resistance/genetics ; *Genes, Protozoan ; Genetic Linkage ; Genetic Loci ; *Genome, Protozoan ; Genome-Wide Association Study ; High-Throughput Screening Assays ; Inhibitory Concentration 50 ; Membrane Transport Proteins/genetics ; Molecular Structure ; Multidrug Resistance-Associated Proteins/genetics ; Mutation ; *Parasitic Sensitivity Tests ; Plasmodium falciparum/*drug effects/*genetics/growth & development/metabolism ; Polymorphism, Single Nucleotide ; Protozoan Proteins/genetics ; Structure-Activity Relationship
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
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