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1Staff View
Publication Date: 2013-07-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antimalarials/*administration & dosage ; Artemisinins/*administration & dosage ; Child ; DNA Mismatch Repair/*genetics ; Disease Eradication/*methods ; Drug Resistance/*genetics ; Humans ; Malaria, Falciparum/parasitology/*prevention & control ; Mutation ; Plasmodium falciparum/drug effects/*geneticsPublished by: -
2J. Straimer ; N. F. Gnadig ; B. Witkowski ; C. Amaratunga ; V. Duru ; A. P. Ramadani ; M. Dacheux ; N. Khim ; L. Zhang ; S. Lam ; P. D. Gregory ; F. D. Urnov ; O. Mercereau-Puijalon ; F. Benoit-Vical ; R. M. Fairhurst ; D. Menard ; D. A. Fidock
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-12-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Antimalarials/*pharmacology ; Artemisinins/*pharmacology ; Cambodia ; Drug Resistance/*genetics ; Genetic Loci ; Humans ; Malaria, Falciparum/drug therapy/parasitology ; Molecular Sequence Data ; Mutation ; Plasmodium falciparum/*drug effects/*genetics ; Protein Structure, Tertiary ; Protozoan Proteins/chemistry/*geneticsPublished by: -
3S. Meister ; D. M. Plouffe ; K. L. Kuhen ; G. M. Bonamy ; T. Wu ; S. W. Barnes ; S. E. Bopp ; R. Borboa ; A. T. Bright ; J. Che ; S. Cohen ; N. V. Dharia ; K. Gagaring ; M. Gettayacamin ; P. Gordon ; T. Groessl ; N. Kato ; M. C. Lee ; C. W. McNamara ; D. A. Fidock ; A. Nagle ; T. G. Nam ; W. Richmond ; J. Roland ; M. Rottmann ; B. Zhou ; P. Froissard ; R. J. Glynne ; D. Mazier ; J. Sattabongkot ; P. G. Schultz ; T. Tuntland ; J. R. Walker ; Y. Zhou ; A. Chatterjee ; T. T. Diagana ; E. A. Winzeler
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-11-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antimalarials/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Cell Line, Tumor ; *Drug Discovery ; Drug Evaluation, Preclinical ; Drug Resistance ; Erythrocytes/parasitology ; Humans ; Imidazoles/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Liver/*parasitology ; Malaria/*drug therapy/parasitology/prevention & control ; Mice ; Mice, Inbred BALB C ; Molecular Structure ; Piperazines/chemistry/pharmacokinetics/*pharmacology/therapeutic use ; Plasmodium/cytology/*drug effects/growth & development/physiology ; Plasmodium berghei/cytology/drug effects/growth & development/physiology ; Plasmodium falciparum/cytology/drug effects/growth & development/physiology ; Plasmodium yoelii/cytology/drug effects/growth & development/physiology ; Polymorphism, Single Nucleotide ; Protozoan Proteins/chemistry/genetics/metabolism ; Random Allocation ; Small Molecule Libraries ; Sporozoites/drug effects/growth & developmentPublished by: -
4C. W. McNamara ; M. C. Lee ; C. S. Lim ; S. H. Lim ; J. Roland ; A. Nagle ; O. Simon ; B. K. Yeung ; A. K. Chatterjee ; S. L. McCormack ; M. J. Manary ; A. M. Zeeman ; K. J. Dechering ; T. R. Kumar ; P. P. Henrich ; K. Gagaring ; M. Ibanez ; N. Kato ; K. L. Kuhen ; C. Fischli ; M. Rottmann ; D. M. Plouffe ; B. Bursulaya ; S. Meister ; L. Rameh ; J. Trappe ; D. Haasen ; M. Timmerman ; R. W. Sauerwein ; R. Suwanarusk ; B. Russell ; L. Renia ; F. Nosten ; D. C. Tully ; C. H. Kocken ; R. J. Glynne ; C. Bodenreider ; D. A. Fidock ; T. T. Diagana ; E. A. Winzeler
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 1-Phosphatidylinositol 4-Kinase/*antagonists & ; inhibitors/chemistry/genetics/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Binding Sites ; Cytokinesis/drug effects ; Drug Resistance/drug effects/genetics ; Fatty Acids/metabolism ; Female ; Hepatocytes/parasitology ; Humans ; Imidazoles/metabolism/pharmacology ; Life Cycle Stages/drug effects ; Macaca mulatta ; Malaria/*drug therapy/*parasitology ; Male ; Models, Biological ; Models, Molecular ; Phosphatidylinositol Phosphates/metabolism ; Plasmodium/classification/*drug effects/*enzymology/growth & development ; Pyrazoles/metabolism/pharmacology ; Quinoxalines/metabolism/pharmacology ; Reproducibility of Results ; Schizonts/cytology/drug effects ; rab GTP-Binding Proteins/genetics/metabolismPublished by: -
5B. Baragana ; I. Hallyburton ; M. C. Lee ; N. R. Norcross ; R. Grimaldi ; T. D. Otto ; W. R. Proto ; A. M. Blagborough ; S. Meister ; G. Wirjanata ; A. Ruecker ; L. M. Upton ; T. S. Abraham ; M. J. Almeida ; A. Pradhan ; A. Porzelle ; M. S. Martinez ; J. M. Bolscher ; A. Woodland ; S. Norval ; F. Zuccotto ; J. Thomas ; F. Simeons ; L. Stojanovski ; M. Osuna-Cabello ; P. M. Brock ; T. S. Churcher ; K. A. Sala ; S. E. Zakutansky ; M. B. Jimenez-Diaz ; L. M. Sanz ; J. Riley ; R. Basak ; M. Campbell ; V. M. Avery ; R. W. Sauerwein ; K. J. Dechering ; R. Noviyanti ; B. Campo ; J. A. Frearson ; I. Angulo-Barturen ; S. Ferrer-Bazaga ; F. J. Gamo ; P. G. Wyatt ; D. Leroy ; P. Siegl ; M. J. Delves ; D. E. Kyle ; S. Wittlin ; J. Marfurt ; R. N. Price ; R. E. Sinden ; E. A. Winzeler ; S. A. Charman ; L. Bebrevska ; D. W. Gray ; S. Campbell ; A. H. Fairlamb ; P. A. Willis ; J. C. Rayner ; D. A. Fidock ; K. D. Read ; I. H. Gilbert
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antimalarials/administration & dosage/adverse ; effects/pharmacokinetics/*pharmacology ; Drug Discovery ; Female ; Gene Expression Regulation/*drug effects ; Life Cycle Stages/drug effects ; Liver/drug effects/parasitology ; Malaria/drug therapy/*parasitology ; Male ; Models, Molecular ; Peptide Elongation Factor 2/antagonists & inhibitors/metabolism ; Plasmodium/*drug effects/genetics/growth & development/*metabolism ; Plasmodium berghei/drug effects/physiology ; Plasmodium falciparum/drug effects/metabolism ; Plasmodium vivax/drug effects/metabolism ; Protein Biosynthesis/*drug effects ; Quinolines/administration & dosage/chemistry/pharmacokinetics/*pharmacologyPublished by: -
6B. S. Crabb ; J. G. Beeson ; R. Amino ; R. Menard ; A. Waters ; E. A. Winzeler ; M. Wahlgren ; D. A. Fidock ; S. Nwaka
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-04-27Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anopheles/parasitology/physiology ; Antigens, Protozoan/immunology ; Antimalarials/pharmacology/therapeutic use ; Artemisinins/pharmacology/therapeutic use ; Biomedical Research/organization & administration/*trends ; Drug Resistance/drug effects ; Erythrocytes/parasitology ; Female ; Hepatocytes/parasitology ; Humans ; Malaria/*drug therapy/epidemiology/immunology/*prevention & control ; Malaria Vaccines/immunology ; Mosquito Control/methods ; Plasmodium/drug effects/growth & development/immunology/metabolism ; Primaquine/administration & dosage/adverse effects/metabolism/therapeutic use ; Sporozoites/immunology ; Vaccines, Attenuated/immunologyPublished by: -
7J. Yuan ; K. C. Cheng ; R. L. Johnson ; R. Huang ; S. Pattaradilokrat ; A. Liu ; R. Guha ; D. A. Fidock ; J. Inglese ; T. E. Wellems ; C. P. Austin ; X. Z. Su
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antimalarials/chemistry/*pharmacology ; Biological Evolution ; Chromosome Mapping ; Drug Combinations ; *Drug Resistance/genetics ; *Genes, Protozoan ; Genetic Linkage ; Genetic Loci ; *Genome, Protozoan ; Genome-Wide Association Study ; High-Throughput Screening Assays ; Inhibitory Concentration 50 ; Membrane Transport Proteins/genetics ; Molecular Structure ; Multidrug Resistance-Associated Proteins/genetics ; Mutation ; *Parasitic Sensitivity Tests ; Plasmodium falciparum/*drug effects/*genetics/growth & development/metabolism ; Polymorphism, Single Nucleotide ; Protozoan Proteins/genetics ; Structure-Activity RelationshipPublished by: -
8Cowell, A. N., Istvan, E. S., Lukens, A. K., Gomez-Lorenzo, M. G., Vanaerschot, M., Sakata-Kato, T., Flannery, E. L., Magistrado, P., Owen, E., Abraham, M., La; Monte, G., Painter, H. J., Williams, R. M., Franco, V., Linares, M., Arriaga, I., Bopp, S., Corey, V. C., Gnädig, N. F., Coburn-Flynn, O., Reimer, C., Gupta, P., Murithi, J. M., Moura, P. A., Fuchs, O., Sasaki, E., Kim, S. W., Teng, C. H., Wang, L. T., Akidil, A., Adjalley, S., Willis, P. A., Siegel, D., Tanaseichuk, O., Zhong, Y., Zhou, Y., Llinas, M., Ottilie, S., Gamo, F.-J., Lee, M. C. S., Goldberg, D. E., Fidock, D. A., Wirth, D. F., Winzeler, E. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-01-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, MicrobiologyPublished by: -
9Antonova-Koch, Y., Meister, S., Abraham, M., Luth, M. R., Ottilie, S., Lukens, A. K., Sakata-Kato, T., Vanaerschot, M., Owen, E., Jado Rodriguez, J. C., Maher, S. P., Calla, J., Plouffe, D., Zhong, Y., Chen, K., Chaumeau, V., Conway, A. J., McNamara, C. W., Ibanez, M., Gagaring, K., Serrano, F. N., Eribez, K., Taggard, C. M., Cheung, A. L., Lincoln, C., Ambachew, B., Rouillier, M., Siegel, D., Nosten, F., Kyle, D. E., Gamo, F.-J., Zhou, Y., Llinas, M., Fidock, D. A., Wirth, D. F., Burrows, J., Campo, B., Winzeler, E. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-12-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Chemistry, Microbiology, Online OnlyPublished by: