Search Results - (Author, Cooperation:C. Yvon)

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  1. 1
    C. Bocklisch ; V. Pascoli ; J. C. Wong ; D. R. House ; C. Yvon ; M. de Roo ; K. R. Tan ; C. Luscher
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-09-28
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cocaine/*pharmacology ; Cocaine-Related Disorders/physiopathology ; Dopaminergic Neurons/*metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neuronal Plasticity/drug effects ; Synaptic Transmission/drug effects/physiology ; Ventral Tegmental Area/*metabolism ; gamma-Aminobutyric Acid/*drug effects/metabolism
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Pérusse, Louis ; Chagnon, Yvon C. ; Bouchard, Claude
    Springer
    Published 1998
    Staff View
    ISSN:
    1432-2323
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract. It is well established that there is a significant familial aggregation of obesity, although most of the evidence regarding the genetic basis of obesity has been derived from overweight and moderately obese cases. Less is known about the contribution of genetic factors in severely obese individuals. This paper reviews the available evidence regarding the extent of familial aggregation of morbid obesity and the contribution of specific genes. The results of available studies suggest a stronger degree of familial resemblance for morbid obesity [body mass index (BMI 〉 40 kg/m2)] than for more moderate levels of obesity (BMI 〈 40 kg/m2). Evidence from human association and linkage studies, performed with markers surrounding human homologs of the genes involved in mouse models of obesity, revealed that these genes tend to be linked more often to severe obesity than to moderate levels of obesity.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002689900493

    Articles: DFG German National Licenses
  3. 3
    Pérusse, Louis ; Chagnon, Yvon C.
    Springer
    Published 1997
    Staff View
    ISSN:
    1573-3297
    Keywords:
    Human obesity ; linkage studies ; association studies ; body fat ; fat distribution ; candidate genes
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Psychology
    Notes:
    Abstract It is now widely accepted that genes play a significant role in the development of human obesity. The mapping of genes contributing to obesity and to regional fat distribution in humans is based on association and linkage studies. This article presents a review of these studies in humans for phenotypes related to excess body mass or body fat and regional fat distribution. The various obesity phenotypes are first defined followed by a brief description of the linkage and association methods. The early association studies based on red blood cell genetic polymorphisms are reviewed and the studies which have reported significant evidence of linkage and association described. Studies with negative findings are not reviewed. Results of these studies suggest a total of 28 genes or chromosomal regions that may be associated and/or linked with body fat and fat distribution phenotypes in human. With genomewide searches for obesity genes actually under way, together with the 16,000 genes and transcripts included in the recent human gene map, this number is likely to increase rapidly in the next few years.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1025640014835

    Articles: DFG German National Licenses