Search Results - (Author, Cooperation:C. Winter)
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1Latest Papers from Table of Contents or Articles in PressClaret, L., Jin, J. Y., Ferte, C., Winter, H., Girish, S., Stroh, M., He, P., Ballinger, M., Sandler, A., Joshi, A., Rittmeyer, A., Gandara, D., Soria, J.-C., Bruno, R.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-07-17Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressK. Wang ; S. J. Diskin ; H. Zhang ; E. F. Attiyeh ; C. Winter ; C. Hou ; R. W. Schnepp ; M. Diamond ; K. Bosse ; P. A. Mayes ; J. Glessner ; C. Kim ; E. Frackelton ; M. Garris ; Q. Wang ; W. Glaberson ; R. Chiavacci ; L. Nguyen ; J. Jagannathan ; N. Saeki ; H. Sasaki ; S. F. Grant ; A. Iolascon ; Y. P. Mosse ; K. A. Cole ; H. Li ; M. Devoto ; P. W. McGrady ; W. B. London ; M. Capasso ; N. Rahman ; H. Hakonarson ; J. M. Maris
Nature Publishing Group (NPG)
Published 2010Staff ViewPublication Date: 2010-12-03Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Line, Tumor ; Cell Proliferation ; Chromosomes, Human, Pair 11/genetics ; DNA Copy Number Variations/genetics ; DNA-Binding Proteins/*genetics ; Disease Progression ; Europe/ethnology ; Gene Duplication/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Genetic Predisposition to Disease/*genetics ; Genome, Human/genetics ; *Genome-Wide Association Study ; Genomics ; Genotype ; Humans ; LIM Domain Proteins ; Neuroblastoma/*genetics/pathology ; Odds Ratio ; Oncogenes/*genetics ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Survival Rate ; Transcription Factors/*geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressD. A. Oldridge ; A. C. Wood ; N. Weichert-Leahey ; I. Crimmins ; R. Sussman ; C. Winter ; L. D. McDaniel ; M. Diamond ; L. S. Hart ; S. Zhu ; A. D. Durbin ; B. J. Abraham ; L. Anders ; L. Tian ; S. Zhang ; J. S. Wei ; J. Khan ; K. Bramlett ; N. Rahman ; M. Capasso ; A. Iolascon ; D. S. Gerhard ; J. M. Guidry Auvil ; R. A. Young ; H. Hakonarson ; S. J. Diskin ; A. T. Look ; J. M. Maris
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-11-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; Alleles ; Allelic Imbalance ; Binding Sites ; DNA-Binding Proteins/*genetics ; Enhancer Elements, Genetic/*genetics ; Epigenomics ; GATA3 Transcription Factor/metabolism ; Gene Expression Regulation, Neoplastic/genetics ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Genotype ; Histones/chemistry/metabolism ; Humans ; Introns/genetics ; LIM Domain Proteins/*genetics ; Lysine/metabolism ; Neuroblastoma/*genetics ; Organ Specificity ; Polymorphism, Single Nucleotide/*genetics ; Reproducibility of Results ; Transcription Factors/*geneticsPublished by: -
4Latest Papers from Table of Contents or Articles in PressBigenzahn, J. W., Collu, G. M., Kartnig, F., Pieraks, M., Vladimer, G. I., Heinz, L. X., Sedlyarov, V., Schischlik, F., Fauster, A., Rebsamen, M., Parapatics, K., Blomen, V. A., Müller, A. C., Winter, G. E., Kralovics, R., Brummelkamp, T. R., Mlodzik, M., Superti-Furga, G.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-12-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, Medicine, DiseasesPublished by: -
5Latest Papers from Table of Contents or Articles in PressS. Giovanoli ; H. Engler ; A. Engler ; J. Richetto ; M. Voget ; R. Willi ; C. Winter ; M. A. Riva ; P. B. Mortensen ; J. Feldon ; M. Schedlowski ; U. Meyer
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-03-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cytokines/immunology ; Disease Models, Animal ; Female ; Humans ; Mental Disorders/*immunology ; Mice ; Mice, Inbred C57BL ; Poly I-C/immunology/pharmacology ; Pregnancy ; Prenatal Exposure Delayed Effects/*immunology/virology ; Puberty/*immunology ; Stress, Physiological/*immunologyPublished by: -
6Articles: DFG German National LicensesStaff View
ISSN: 0031-9422Keywords: 2-oxo-4-methylglutaric acid ; 4-methyleneglutamic acid ; 4-methyleneglutamine ; 4-methylglutamic acid ; 4-substituted glutamic acids ; Leguminoseae ; Sophora japonica ; transamination.Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1573-3343Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesWinter, C. S. ; Oliver, S. N. ; Rush, J. D. ; Hill, C. A. S. ; Underhill, A. E.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The third-order optical nonlinearity χ(3) of two novel guest-host polymers has been measured. The polymers consisted of nickel dithiolene guest molecules in a polymethylmethacrylate host and were prepared as cast or spun films. The optical nonlinearity was measured by degenerate four-wave-mixing experiments at a wavelength of 1.06 μm using 100-ps laser pulses. χ(3) coefficients of up to 10−17 m2/V2 were observed, corresponding to nonlinear refractive index n2 of up to 10−8 cm2/kW with a damage threshold (approximately-greater-than)1 GW/cm2.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesWinter, C. S. ; Hill, C. A. S. ; Underhill, A. E.
Woodbury, NY : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The third-order optical nonlinearity χ(3), linear absorption coefficient α, and the two-photon absorption coefficient β of two nickel dithiolene complexes are reported. The nonlinearities were measured at 1064 nm using 100 ps pulses. Molecular nonlinearities 103 times those of carbon disulphide were observed. Two figures of merit were calculated from the data Δnsat/αλ=5 and n2/2βλ(approximately-greater-than)2, where α and β are the linear and two-photon absorption coefficients and n2 the nonlinear refractive index. These figures are compatible with those required for simple all-optical switching devices.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesSanders, Benjamin E. ; Smith, E. V. C. ; Flataker, L. ; Winter, C. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1962Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesAttilakos, G. ; Sibanda, T. ; Winter, C. ; Johnson, N. ; Draycott, T.
Oxford, UK and Malden, USA : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objective To evaluate the effectiveness of a new handheld vacuum delivery device.Design Randomised controlled trial.Setting Southmead Hospital, Bristol, UK.Population One hundred and ninety-four women requiring delivery with vacuum extraction.Methods Women were recruited into the study while still in early labour. If during delivery, vacuum extraction was indicated they were then randomly allocated to either a new handheld vacuum device, the Kiwi Omnicup, or to a ‘standard’ vacuum cup selected by the obstetrician. The ‘standard group’ consisted of the silastic (66/98, 67%) or the metal cups (32/98, 33%). Study data were recorded at completion of the delivery and at 24–48 hours. An additional brief symptom questionnaire was completed by the mother at 10 days postnatally. Statistical analyses were done on an ‘intention-to-treat’ basis.Main outcome measures The primary outcome was the successful completion of delivery with the allocated instrument. Secondary outcomes were substantial fetal scalp trauma and substantial maternal trauma.Results The Omnicup was associated with a significantly higher failure rate than the standard cup [34%vs 21%, odds ratio (OR) = 1.9 (1.01–3.6)]. This difference persisted after adjusting for confounding factors [adjusted OR = 2.25 (1.01–5.0)] and resulted in significantly more forceps deliveries in the Kiwi Omnicup group [22%vs 10%, unadjusted OR = 2.5 (1.1–5.5)]. The caesarean section rates were similar in both groups [9.4%vs 8.2%, OR = 1.2 (0.4–3.2)]. Rates of substantial scalp trauma and maternal trauma were similar in both groups. However, there were more cases of jaundice in the standard cup group [2.3%vs 12.0%, unadjusted OR = 0.18 (0.04–0.82) and adjusted OR = 0.10 (0.01–0.88)].Conclusions The Omnicup is not as successful at achieving a vaginal delivery as the combination of the currently used vacuum cups.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesHolt, T. G. ; Chang, C. ; Laurent-Winter, C. ; Murakami, T. ; Garrels, J. I. ; Davies, J. E. ; Thompson, C. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Two-dimensional gel electrophoresis was used to follow low changes in gene expression associated with antibiotic (bialaphos) biosynthesis in Streptomyces hygroscopicus. Cultures were pulse-labelled with [35S]-methionine before, during, and after the switch from primary to secondary metabolism in order to compare kinetic profiles of bialaphos (antibiotic) production (bap) genes during this metabolic transition. Separation of gene products on two-dimensional gels revealed that 27 were dependent on brpA for optimal expression and were activated as the culture approached stationary phase. Genes which encoded 10 brp4-dependent proteins were mapped to a 10 kb Sstl fragment of the 35 kb bap gene cluster by expressing them in Streptomyces lividans using the thiostrepton-inducible tipA promoter. N-terminal amino acid sequences of two brpA-dependent proteins, obtained by direct microsequencing of protein spots excised from two-dimensional gels, identified them as gene products mapping to the same region and involved in secondary metabolic conversions of the bap pathway. The kinetics of synthesis of 16 brpA-dependent gene products were characterized using QUEST computer software. Cluster analysis performed on the kinetics of synthesis of 346 of the most highly expressed gene products of HP5-29, including 16 brpA-dependent ones, identified 75 families having distinct patterns of expression. Many brpA-dependent proteins were clustered together; 10 were found in one kinetic family. These kinetic families also included brpA-independent gene products perhaps subject to similar regulatory mechanisms and thus possibly involved in bialaphos biosynthesis. The activation/derepression of bap expression took place as cultures approached stationary phase and was temporally related to synthesis of ppGpp.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesWelzel, J. ; Reinhardt, C. ; Lankenau, E. ; Winter, C. ; Wolff, H.H.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Optical coherence tomography (OCT) is a noninvasive morphological method for investigating human skin. It allows high-resolution in vivo imaging of inflammatory skin diseases and tumours. Because it is a newly developed method, systematic studies on standardization and on evaluation of factors influencing the representation of the skin have not yet been performed.Objectives In this study, normal human skin was treated with various external stimuli which induce changes of function and morphology. Changes in stratum corneum thickness as well as changes induced by pigmentation, oedema and erythema were investigated using OCT.Methods Healthy skin of human volunteers was treated with tape stripping, ultraviolet A irradiation, water, histamine, nicotinic acid and various ointments.Results In the tape stripping experiment, the thickness of the horny layer was quantified and monitored. Pigmentation increased the light attenuation of the tissue, whereas hydration and erythema led to a slight decrease of scattering. Topical treatment of the skin gave a nonspecific increase of penetration depth of the light due to the lower reflectivity of the surface.Conclusions There are various physiological conditions which influence optical properties of the skin. These parameters should be considered when performing standardized OCT studies.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0003-4916Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0921-4526Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Keywords: Development ; Human ; Muscle ; Myosin light chain ; Tropomyosin ; Two-dimensional electrophoresisSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesRiedinger, M. ; Schmitt, F. ; Metzger, G. ; Sutter, G. ; Chevallier, P. ; Winter, C.
Amsterdam : ElsevierStaff ViewISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesPeter Braun-Munzinger for the E814 Collaboration ; Barrette, J. ; Bellwied, R. ; Braun-Munzinger, P. ; Cleland, W.E. ; Cormier, T.M. ; David, G. ; Dee, J. ; Hong, B. ; Shiva Kumar, B. ; Pruneau, C. ; Winter, C. ; Zou, C. ; Woody, C.L. ; Fox, D. ; Kraus, D. ; Lissauer, D. ; Wolfe, D. ; O'Brien, E. ; Takagui, E.M. ; Rotondo, F. ; Ingold, G. ; Wang, G. ; Diebold, G.E. ; Takai, H.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesBarrette, J. ; Bellwied, R. ; Braun-Munzinger, P. ; Cleland, W.E. ; Cormier, T. ; David, G. ; Dee, J. ; Dietzsch, O. ; Hong, B. ; Shiva Kumar, B. ; Pruneau, C. ; Winter, C. ; Zou, C. ; Woody, C.L. ; Fox, D. ; Kraus, D. ; Lissauer, D. ; Makowiecki, D. ; Wolfe, D. ; Duek, E. ; O'Brien, E. ; Takagui, E.M. ; Rotondo, F.S. ; Takai, H. ; Sandweiss, J.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: