Search Results - (Author, Cooperation:C. Simpson)
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1Latest Papers from Table of Contents or Articles in PressSoyiri, I. N., Sheikh, A., Reis, S., Kavanagh, K., Vieno, M., Clemens, T., Carnell, E. J., Pan, J., King, A., Beck, R. C., Ward, H. J. T., Dibben, C., Robertson, C., Simpson, C. R.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-05-22Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Respiratory medicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressA. Wakhle, K. Hammerton, Z. Kohley, D. J. Morrissey, K. Stiefel, J. Yurkon, J. Walshe, K. J. Cook, M. Dasgupta, D. J. Hinde, D. J. Jeung, E. Prasad, D. C. Rafferty, C. Simenel, E. C. Simpson, K. Vo-Phuoc, J. King, W. Loveland, and R. Yanez
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-03-06Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
3Latest Papers from Table of Contents or Articles in PressG. Mohanto, D. J. Hinde, K. Banerjee, M. Dasgupta, D. Y. Jeung, C. Simenel, E. C. Simpson, A. Wakhle, E. Williams, I. P. Carter, K. J. Cook, D. H. Luong, C. S. Palshetkar, and D. C. Rafferty
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-05-10Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
4Latest Papers from Table of Contents or Articles in PressK. J. Cook, I. P. Carter, E. C. Simpson, M. Dasgupta, D. J. Hinde, L. T. Bezzina, Sunil Kalkal, C. Sengupta, C. Simenel, B. M. A. Swinton-Bland, K. Vo-Phuoc, and E. Williams
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-02-10Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
5Latest Papers from Table of Contents or Articles in PressJ. Khuyagbaatar, H. M. David, D. J. Hinde, I. P. Carter, K. J. Cook, M. Dasgupta, Ch. E. Düllmann, D. Y. Jeung, B. Kindler, B. Lommel, D. H. Luong, E. Prasad, D. C. Rafferty, C. Sengupta, C. Simenel, E. C. Simpson, J. F. Smith, K. Vo-Phuoc, J. Walshe, A. Wakhle, E. Williams, and A. Yakushev
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-06-29Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
6Latest Papers from Table of Contents or Articles in PressD. J. Hinde, D. Y. Jeung, E. Prasad, A. Wakhle, M. Dasgupta, M. Evers, D. H. Luong, R. du Rietz, C. Simenel, E. C. Simpson, and E. Williams
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-02-24Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear ReactionsPublished by: -
7Latest Papers from Table of Contents or Articles in PressS. Finnegan ; S. C. Anderson ; P. G. Harnik ; C. Simpson ; D. P. Tittensor ; J. E. Byrnes ; Z. V. Finkel ; D. R. Lindberg ; L. H. Liow ; R. Lockwood ; H. K. Lotze ; C. R. McClain ; J. L. McGuire ; A. O'Dea ; J. M. Pandolfi
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-05-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Aquatic Organisms ; *Biodiversity ; *Climate Change ; *Extinction, Biological ; Fossils ; *Human Activities ; Humans ; *Oceans and Seas ; Paleontology ; RiskPublished by: -
8Latest Papers from Table of Contents or Articles in PressE. Petrillo ; M. A. Godoy Herz ; A. Fuchs ; D. Reifer ; J. Fuller ; M. J. Yanovsky ; C. Simpson ; J. W. Brown ; A. Barta ; M. Kalyna ; A. R. Kornblihtt
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-04-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Alternative Splicing ; Arabidopsis/*genetics/metabolism ; Arabidopsis Proteins/genetics/metabolism ; Cell Nucleus/genetics ; Chloroplasts/*metabolism ; Circadian Clocks ; Dibromothymoquinone/pharmacology ; Diuron/pharmacology ; Electron Transport/drug effects ; *Gene Expression Regulation, Plant ; Light ; Models, Biological ; Oxidation-Reduction ; Photosynthesis/drug effects ; Plant Leaves/metabolism ; Plant Roots/metabolism ; Plants, Genetically Modified ; Plastoquinone/*metabolism ; RNA Stability ; RNA, Messenger/genetics/metabolism ; RNA, Plant/genetics/metabolism ; Seedlings/genetics/metabolism ; Signal TransductionPublished by: -
9Latest Papers from Table of Contents or Articles in PressD. J. Mortlock ; S. J. Warren ; B. P. Venemans ; M. Patel ; P. C. Hewett ; R. G. McMahon ; C. Simpson ; T. Theuns ; E. A. Gonzales-Solares ; A. Adamson ; S. Dye ; N. C. Hambly ; P. Hirst ; M. J. Irwin ; E. Kuiper ; A. Lawrence ; H. J. Rottgering
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
10Latest Papers from Table of Contents or Articles in PressR. Durst ; K. Sauls ; D. S. Peal ; A. deVlaming ; K. Toomer ; M. Leyne ; M. Salani ; M. E. Talkowski ; H. Brand ; M. Perrocheau ; C. Simpson ; C. Jett ; M. R. Stone ; F. Charles ; C. Chiang ; S. N. Lynch ; N. Bouatia-Naji ; F. N. Delling ; L. A. Freed ; C. Tribouilloy ; T. Le Tourneau ; H. LeMarec ; L. Fernandez-Friera ; J. Solis ; D. Trujillano ; S. Ossowski ; X. Estivill ; C. Dina ; P. Bruneval ; A. Chester ; J. J. Schott ; K. D. Irvine ; Y. Mao ; A. Wessels ; T. Motiwala ; M. Puceat ; Y. Tsukasaki ; D. R. Menick ; H. Kasiganesan ; X. Nie ; A. M. Broome ; K. Williams ; A. Johnson ; R. R. Markwald ; X. Jeunemaitre ; A. Hagege ; R. A. Levine ; D. J. Milan ; R. A. Norris ; S. A. Slaugenhaupt
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-08-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Body Patterning/genetics ; Cadherins/deficiency/*genetics/*metabolism ; Cell Movement/genetics ; Chromosomes, Human, Pair 11/genetics ; Female ; Humans ; Male ; Mice ; Mitral Valve/abnormalities/embryology/pathology/surgery ; Mitral Valve Prolapse/*genetics/*pathology ; Mutation/*genetics ; Pedigree ; Phenotype ; Protein Stability ; RNA, Messenger/genetics ; Zebrafish/genetics ; Zebrafish Proteins/genetics/metabolismPublished by: -
11Articles: DFG German National LicensesStaff View
ISSN: 1612-1112Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Latest Papers from Table of Contents or Articles in PressLin-Shiao, E., Lan, Y., Coradin, M., Anderson, A., Donahue, G., Simpson, C. L., Sen, P., Saffie, R., Busino, L., Garcia, B. A., Berger, S. L., Capell, B. C.
Cold Spring Harbor Laboratory Press
Published 2018Staff ViewPublication Date: 2018-02-16Publisher: Cold Spring Harbor Laboratory PressPrint ISSN: 0890-9369Topics: BiologyPublished by: -
13Articles: DFG German National LicensesStaff View
ISSN: 1525-1314Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesNotes: Several examples of deformation-induced myrmekite have been found in two amphibolite facies mylonites derived from granitic protoliths, namely a muscovite-poor S-C mylonite and a single foliation, muscovite-poor mylonitic gneiss. Back-scattered SEM and conventional optical microscopy show that in both rock types, syntectonic myrmekitic intergrowths of oligoclase and quartz formed on the two sides of K-feldspar grains that faced the local inferred incremental shortening direction for the mylonite. Myrmekite does not occur on the two ends of the grain that faced the incremental stretching direction.The replacement of K-feldspar by plagioclase and quartz results in a volume decrease and is favoured on high normal stress sites around the grains. We suggest that the ambient temperature, pressure and chemical activities were such that the replacement reaction was favoured, but the addition of extra strain energy along the high-pressure sides of the grains localized the reaction at these sites. This energy could arise from elastic strain, or strain associated with tangled dislocations or twin boundaries. The relative roles of stress and strain energy concentrations in driving the replacement reaction are not known, but both were probably important.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Administration of neuroleptics such as haloperidol to rats is known to induce the expression of the immediate-early genes (IEGs) c-fos and zif/268 in striatal neurones. Another IEG, junB, is of interest because it may be involved in the suppression, rather than the enhancement, of downstream gene transcription. In this study, rat striatal tissue was assayed for IEG expression by in situ hybridisation, after the injection of haloperidol (1 mg/kg) or fluphenazine (3 mg/kg). In addition to c-fos mRNA and zif/268 mRNA, neurones in both the striatum and nucleus accumbens were found to contain high levels of junB mRNA, after treatment with either haloperidol or fluphenazine. The proportion of striatal neurones expressing junB mRNA strongly suggests that induction occurs in striatal projection neurones. A significant increase in the levels of the mRNA encoding another IEG, junD, was also detected after haloperidol treatment. The atypical neuroleptic clozapine (3 mg/kg) did not induce the expression of any of these IEGs in striatal tissue. The results show additional complexity in the pattern of IEG induction after neuroleptic administration and suggest that junB is involved in mediating some of the effects of neuroleptics on striatal gene expression.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Nitric oxide (NO), an intercellular messenger in the brain, has been implicated in both neuronal plasticity and neurotoxicity. It has been suggested that NO can activate the DNA binding activity of nuclear factor κB (NF-κB) family proteins in some cell types while having an inhibitory effect in others. In this study we have investigated the effect of acute NO in primary neuronal cultures of rat striatum using immunohistochemistry. Exposure of neurones to the NO-mimetic S-nitroso-n-acetylpenicillamine (SNAP; 200 μM) and to bacterial lipopolysaccharide (LPS; 10 μg/ml) for 30 min increased nuclear protein expression of the p50 subunit of NF-κB. SNAP also enhanced nuclear protein expression of the p65 subunit of NF-κB. Simultaneously, the cytoplasmic expression of phosphorylated inhibitory protein IκBα was dramatically increased by SNAP (200 μM), LPS (10 μg/ml), and kainate (50 μM) treatment. In the adult rat, stimulation with NOR-3 (2 mg/kg), a NO donor, increased NF-κB DNA binding activity in the striatum after 45 min. Because glucocorticoids inhibit NF-κB activity, primary cultures were pretreated with dexamethasone (50 μM) before SNAP, LPS, and kainate treatment, and the effect on the protein expression level of the individual subunits p50 and p65 present in the classical form of the transcription factor NF-κB was assessed. Dexamethasone pretreatment resulted in a marked reduction of p65 protein in striatal neurones after SNAP, LPS, and kainate, whereas p50 expression was reduced by dexamethasone pretreatment only after an LPS stimulus. This study indicates that NO-releasing compounds can directly induce nuclear NF-κB subunit expression in rat striatum and that glucocorticoids selectively inhibit p65 subunit expression following exposure to NO.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesColchin, R. J. ; Anderson, F. S. B. ; England, A. C. ; Gandy, R. F. ; Harris, J. H. ; Henderson, M. A. ; Hillis, D. L. ; Kindsfather, R. R. ; Lee, D. K. ; Million, D. L. ; Murakami, M. ; Neilson, G. H. ; Saltmarsh, M. J. ; Simpson, C. M.
[S.l.] : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The beam from an electron gun was used to trace flux surfaces in the Advanced Toroidal Facility (ATF) torsatron. The ATF magnetic field was run steady state at 0.1 T, and the electron beam was detected optically with an image-intensified, solid-state camera when it impinged on a phosphor-coated screen. Closed flux surfaces and islands at several low-order resonances were observed. The largest island, located at the ι= 1/2 surface, was from 5 to 6 cm in width, and its presence implied the existence of magnetic field errors. To determine if these error fields could be traced to small misalignments of the magnetic coils, a device capable of accurately measuring the radial and vertical magnetic field components of individual coil sets was placed in the center of ATF. This device allowed for a determination of the precise location of each of the coils that make up the ATF coil set. No significant coil misalignments were found. A further investigation of the coil configuration led to the identification of dipole fields in the helical field coil leads as the source of the field errors. The techniques developed in making these measurements are described in the text.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesAdrenalectomy-Produced Facilitation of Pavlovian Conditioned Cardiodecelerations in Immobilized RatsWilson, J. Roger ; Simpson, C. Wayne ; DiCara, Leo V. ; Carroll, Bernard J.
Oxford, UK : Blackwell Publishing Ltd
Published 1977Staff ViewISSN: 1469-8986Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Previous evidence has suggested that both hormonal and behavioral aspects of adrenal stress activation may contribute to heart rate (HR) conditioning during physical/pharmacological immobilization. Accordingly, four studies were conducted to determine if bilateral adrenalectomy facilitates stimulus-control over Pavlovian conditioned cardiodecelerations in rats immobilized either through physical restraint or neuromuscular paralysis. Plasma corticosterone assays were used as an index of the effectiveness of adrenal removal. The results showed that adrenalectomy facilitated both simple and discriminated Pavlovian conditioned cardiodecelerations in rats paralyzed with d-tubocurarine chloride (dTC) without significantly altering the characteristics of EMG recovery from paralysis. Similarly, adrenalectomy facilitated simple Pavlovian HR conditioning in physically restrained rats. The results suggest that adrenal activation may disrupt the parasympathetically-mediated Pavlovian conditioned cardiodeceleration in the physically-and dTC-immobilized rat. However, the specific nature of neuroendocrine mechanisms underlying cardiovascular conditioning during immobilization remains problematical.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesTurnidge, M. L. ; Simpson, C. J. S. M.
Woodbury, NY : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: CO has been detected down to 500 parts per trillion by volume using infrared excitation of CO dissolved in liquid Ar solution with laser induced fluorescence detection. The feasibility of the in situ detection of trace concentrations of atmospheric and industrial pollutants dissolved in liquid air is discussed. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesReid, J. P. ; Simpson, C. J. S. M. ; Quiney, H. M. ; Hutson, J. M.
College Park, Md. : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Calculations of the vibrational relaxation rate constants of the CO–3He and CO–4He systems are extended to lower temperatures than in any previous calculation and a comparison made with new experimental results in the temperature range 35–295 K for CO–3He and previously published results in the range 35–2300 K for CO–4He. Both the coupled states (CS) and infinite-order sudden (IOS) approximations are used, with the self-consistent-field configuration interaction CO–He interaction potential of Diercksen and co-workers. The CS approximation is found to give a similar level of agreement with experiment for the two isotopic species, while the performance of the IOS approximation is system dependent. The discrepancy between experimental and theoretical IOS rate constants is quite different for collisions involving 3He and 4He, so that it is not profitable to compare IOS results directly with experiment for these two systems at temperatures below 300 K. The differences between the measured and the CS calculated rate constants for both the CO–4He and CO–3He systems are thought to be due predominantly to inaccuracies in the interaction potential. Relaxation rate constants for CO target molecules in collision with HD, D2 and H2 are compared with results involving 3He, 4He, and "2He,'' revealing some systematic trends depending only on mass. However, for all hydrogen species there are marked upturns in the rate constants at low temperatures relative to those for helium atoms, while the rate constants for HD are greater than those for 3He throughout the temperature range. Calculations at small initial kinetic energies for the CO–He systems reveal an unexpected increase in relaxation cross section with reduction in kinetic energy. This implies that at very low temperatures the CO–He rate constants will show an upturn with decreasing temperature. The fact that this effect is smaller than that for the CO-hydrogen systems and occurs at lower temperatures is consistent with the shallower CO–He attractive well compared with that for CO–H2. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesWilson, G. J. ; Turnidge, M. L. ; Reid, J. P. ; Simpson, C. J. S. M.
College Park, Md. : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Rate constants are presented for (VV) energy transfer between CO(ν=1) and CO2(0001) in the gas phase down to 115 K and in liquid Kr solution at 118 and 130 K. Four isotopically substituted systems were investigated for which the energy mismatches varied between 104 and 306 cm−1. The gas and liquid phase data show several systematic effects with changing energy mismatch. In particular it was found that the ratio of the liquid and gas phase rate constants at the same temperature, kL/kG, increased with decreasing energy mismatch. This is not predicted by current theories of liquid phase energy transfer and is in contrast to previous work using liquid Kr as the solvent. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: