Search Results - (Author, Cooperation:C. Roper)

Showing 1 - 9 results of 9, query time: 0.19s Refine Results
  1. 1
    M. Manske ; O. Miotto ; S. Campino ; S. Auburn ; J. Almagro-Garcia ; G. Maslen ; J. O'Brien ; A. Djimde ; O. Doumbo ; I. Zongo ; J. B. Ouedraogo ; P. Michon ; I. Mueller ; P. Siba ; A. Nzila ; S. Borrmann ; S. M. Kiara ; K. Marsh ; H. Jiang ; X. Z. Su ; C. Amaratunga ; R. Fairhurst ; D. Socheat ; F. Nosten ; M. Imwong ; N. J. White ; M. Sanders ; E. Anastasi ; D. Alcock ; E. Drury ; S. Oyola ; M. A. Quail ; D. J. Turner ; V. Ruano-Rubio ; D. Jyothi ; L. Amenga-Etego ; C. Hubbart ; A. Jeffreys ; K. Rowlands ; C. Sutherland ; C. Roper ; V. Mangano ; D. Modiano ; J. C. Tan ; M. T. Ferdig ; A. Amambua-Ngwa ; D. J. Conway ; S. Takala-Harrison ; C. V. Plowe ; J. C. Rayner ; K. A. Rockett ; T. G. Clark ; C. I. Newbold ; M. Berriman ; B. MacInnis ; D. P. Kwiatkowski
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; *Biodiversity ; Genome, Protozoan ; Genotype ; *High-Throughput Nucleotide Sequencing ; Humans ; Malaria, Falciparum/*parasitology ; Phylogeny ; Plasmodium falciparum/classification/*genetics ; Polymorphism, Single Nucleotide ; Principal Component Analysis
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Mendez, A. J. ; Roper, C. D. ; Dunham, J. D. ; Clegg, T. B.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    An atomic beam polarized ion source, used heavily since 1989 for producing polarized H± and D± beams for experiments between 25 keV and 20 MeV, has been modified to accept a Lamb shift, spin-filter polarimeter. In this source, polarized ground-state H or D atoms enter an electron cyclotron resonance ionizer where they are stripped to produce an outgoing positive polarized ion beam. When negative ions are desired, cesium vapor is introduced into a downstream charge-exchange canal. The polarimeter, based on an atomic physics concept first developed to produce nuclear-spin-polarized beams at Los Alamos, is designed to monitor the polarization of 2S1/2 metastable H or D atoms emerging from the cesium canal. Metastable 2S1/2 atoms created by electron pickup in a collision with cesium are "filtered'' by the polarimeter according to magnetic substate, as the magnetic field imposed on the polarimeter cavity is tuned between 53 and 61 mT. Photons produced by subsequent quenching of these filtered atoms to their ground state are monitored downstream by a phototube to reveal the magnetic substate population of the incident positive beam. To install the polarimeter cavity and phototube assembly, the existing polarized ion source was lengthened by 30 cm. Installation is complete, and comparisons with calibrated nuclear polarimeters have shown agreement to better than 0.023. Principles of operation, a description of the hardware, measurements for cross calibration, and impressions gained from its use are all presented. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1147432

    Articles: DFG German National Licenses
  3. 3
    Mendez, A. J. ; Roper, C. D. ; Dunham, J. D. ; Clegg, T. B.

    [S.l.] : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    An atomic beam polarized ion source, used heavily since 1989 for producing polarized H± and D± beams for experiments between 25 keV and 20 MeV, have been modified to accept a Lamb–shift, spin–filter polarimeter. In this source, polarized ground-state H or D atoms enter an electron cyclotron resonance ionizer where they are stripped to produce an outgoing positive polarized ion beam. When negative ions are desired, cesium vapor is introduced into a downstream charge-exchange canal. The polarimeter, based on an atomic physics concept first developed to produce nuclear–spin-polarized beams at Los Alamos, is designed to monitor the polarization of 2S1/2 metastable H or D atoms emerging from this cesium canal. Metastable 2S1/2 atoms created by electron pickup in a collision with cesium are "filtered'' by the polarimeter according to a magnetic substate, as the magnetic field imposed on the polarimeter cavity is tuned between 53 and 61 mT. Photons produced by subsequent quenching of these filtered atoms to their ground state are monitored downstream by a phototube to reveal the magnetic substate population of the incident positive beam. To install the polarimeter cavity and phototube assembly, the existing polarized ion source was lengthened by 30 cm. Installation is complete, its calibration has been checked, and initial impressions gained from its use are presented. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1146684

    Articles: DFG German National Licenses
  4. 4
    Arnot, D.E. ; Roper, C. ; Sultan, A.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0169-4758
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0169-4758(94)90090-6

    Articles: DFG German National Licenses
  5. 5
    Arnot, D.E. ; Roper, C. ; Bayoumi, R.A.L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0166-6851
    Keywords:
    DNA fingerprints ; Hypervariable sequence ; Plasmodium falciparum ; [abr] CS; circumsporozoite ; [abr] PCR; polymerase chain reaction
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0166-6851(93)90154-P

    Articles: DFG German National Licenses
  6. 6
    Young, R. E. ; Roper, C. F. E. ; Walters, J. F.
    Springer
    Published 1979
    Staff View
    ISSN:
    1432-1793
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The means of detecting downwelling light for counterillumination in several midwater animals has been examined. Eyes and extraocular photoreceptors (drosal photosensitive vesicles in the enoploteuthid squid Abraliopsis sp. B and pineal organs in the myctophid fish Myctophum spinosum) were alternately exposed to overhead light or covered by a small opaque shield above the animal and the bioluminescent response of the animal was monitored. Covering either the eyes or the extraocular photoreceptors resulted in a reduction in the intensity of counterillumination. Preliminary experiments examining the bioluminescent feedback mechanism for monitoring intensity of bioluminescence during counterillumination in the midwater squid Abralia trigonura indicated that the ventral photosensitive vesicles are responsible for bioluminescent feedback.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00389215

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1432-5411
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract High-accuracy differential cross-section data for neutron-deuteron elastic scattering at centre-of-mass backward angles in the range from 140° to 178° have been measured to accuracies better than ±3% for incident neutron energies of 8.0, 10.0, and 14.0 MeV. The measurements were made by detection of the recoil deuterons and protons from a mixed CD2-CH2 foil. The new data are compared to existing data and to three-nucleon calculations with the Bonn-B nucleon-nucleon potential. We conclude that the present measurements unambiguously resolve the discrepancies among previously reported data of the same type.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01355285

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1432-0738
    Keywords:
    Key words Flow through diffusion cell ; Static diffusion cell ; In vitro skin ; Dodecyl decaethoxylate ; Occlusion.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract  Percutaneous absorption of a lipophilic surfactant, dodecyl decaethoxylate, can be predicted using in vitro models. In vivo, dermal penetration of dodecyl decaethoxylate was found to be 22.9% in 48 h. All of the absorbed dodecyl decaethoxylate in the rat was metabolised and excreted in expired air as carbon dioxide, or in the urine and faeces. Using rat skin mounted in the unoccluded flow-through diffusion cell with MEM as receptor fluid, in vivo absorption was predicted by the percentage of the applied dose recovered in the stratum corneum, epidermis, dermis and receptor fluid at 24 h (25%). Conversely, the penetration of dodecyl decaethoxylate was over-predicted in the unoccluded static diffusion cell using aqueous ethanol (50% v/v) as the receptor fluid where 49.4% recovered in the receptor fluid at 24 h. In vitro models may be used to predict percutaneous absorption and reduce animal use, provided a suitable receptor fluid is used in which the penetrant is soluble. Dermal metabolism of dodecyl decaethoxylate was low and not considered to influence dermal absorption.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002040050227

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1432-1793
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract Several tissues (e.g. kidney, blood, digestive gland) in oceanic cephalopods which do not exhibit in vivo bioluminescence, luminesce when homogenized in the presence of air or when simply exposed to air in a vial (blood). The source of the luminescence appears to be a luciferin: treatment of kidney homogenates and blood with a photophore extract presumably containing luciferase resulted in a 20-fold increase in light production. Luminescence was also found in the renal fluid, which may be the source of luminescent clouds produced by squids. The variability in luminescence found in some tissues of cephalopods appeared to be related to feeding. Luminescence was also detected in the digestive glands of midwater octopods.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00386530

    Articles: DFG German National Licenses