Search Results - (Author, Cooperation:C. R. Gerfen)

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  1. 1
    N. Li ; T. W. Chen ; Z. V. Guo ; C. R. Gerfen ; K. Svoboda
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-03-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Behavior, Animal/physiology ; Brain Stem/cytology/physiology ; Electrophysiology ; Mice ; Motor Cortex/cytology/*physiology ; Movement/*physiology ; Neural Pathways/cytology/*physiology ; Pyramidal Cells/cytology/physiology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-04-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Atlases as Topic ; Axons/physiology ; Brain/*anatomy & histology/*cytology ; Cerebral Cortex/cytology ; *Connectome ; Corpus Striatum/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Models, Neurological ; Neuroanatomical Tract-Tracing Techniques ; Thalamus/cytology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2015-03-06
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Gerfen, C. R. ; O'Leary, D. D. M. ; Cowan, W. M.
    Springer
    Published 1982
    Staff View
    ISSN:
    1432-1106
    Keywords:
    Wheat germ agglutinin conjugated horse-radish peroxidase ; Transneuronal transport ; Chick visual system ; Visual cortex
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary While using horseradish peroxidase conjugated to the plant lectin wheat germ agglutinin (WGA-HRP) as an anterograde marker to label the developing retinofugal projection in the chick, we have found that a significant amount of the tracer can escape from the axons and axon terminals of retinal ganglion cells and be subsequently taken up and transported both anterogradely and retrogradely by neighboring neurons and/or axon terminals. The release and uptake of the tracer appears to be nonspecific, and is particularly striking at embryonic stages; at these stages there is also appreciable uptake of the WGA-HRP by ependymal cells and by radial glial processes. Subsequent experiments in rats have shown that as early as 2 days after an injection of WGA-HRP into an eye there is clear labeling of geniculo-cortical axons in the striate cortex. Since WGA-HRP is being used increasingly in neuroanatomical studies, it is now clear that when interpreting the results of experiments with this marker the possibility of transneuronal labeling must be borne in mind, and especially after relatively long post-labeling survival periods. At the same time the secondary transport of WGA-HRP may, in certain neural systems, provide a useful tool for analyzing second-order connections.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses